Abstract:
INTRODUCTION:The aim of our study was to determine the epidemiological profile and the antibiotics susceptibility of bacteria identified in blood culture in the intensive care unit, to improve empirical antibiotherapy. MATERIAL AND METHOD:A retrospective study was made over a four-year period (2002-2005) in the intensive care unit of the Mohammed-V Military Hospital. It included all the bacteria identified in blood culture. RESULTS:During this period, we collected 286 isolates, Gram-negative bacilli 49.3% and Gram-positive cocci 46.85%. The most frequently identified species were Acinetobacter baumannii (13.63%), Staphylococcus epidermidis (12.6%), Staphylococcus aureus (11.9%), and Pseudomonas aeruginosa (7%). Enterobacteriaceae accounted for 25.54%: Klebsiella pneumoniae 7%, and Enterobacter cloacae 7%. The rate of methicillin-resistant Staphylococcus aureus was 52.94 % and coagulase negative staphylococci 60.24%. No resistance to glycopeptides was observed. Enterobacteriaceae were resistant to third generation cephalosporins in 42.6 % and had a broad-spectrum betalactamase phenotype in 18%. The resistance rate of A. baumannii was 68.7% for ceftazidime and 31.4% for imipenem. The resistance rate of P. aeruginosa to the third generation cephalosporines and the imipenem were respectively 16.6% and 10.5%. CONCLUSION:A regular epidemiologic study of blood culture isolates and determination of susceptibility to antibiotics are necessary to improve empiric therapy.
journal_name
Med Mal Infectjournal_title
Medecine et maladies infectieusesauthors
Elouennass M,Sahnoun I,Zrara A,Bajjou T,Elhamzaoui Sdoi
10.1016/j.medmal.2007.10.006subject
Has Abstractpub_date
2008-01-01 00:00:00pages
18-24issue
1eissn
0399-077Xissn
1769-6690pii
S0399-077X(07)00333-2journal_volume
38pub_type
杂志文章abstract:INTRODUCTION:No therapy has yet proven effective in COVID-19. Tocilizumab (TCZ) in patients with severe COVID-19 could be an effective treatment. METHOD:We conducted a retrospective case-control study in the Nord Franche-Comté Hospital, France. We compared the outcome of patients treated with TCZ and patients without ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2020.05.001
更新日期:2020-08-01 00:00:00
abstract::Staphylococcus aureus nasal colonization is a well-known independent risk factor for infection caused by this bacterium. Screening and decolonization of carriers have been proven effective in reducing S. aureus infections in some populations. However, a gap remains between what has been proven effective and what is cu...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2016.10.005
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVES:Adults with hematological malignancies are at high-risk of Clostridium difficile infection (CDI), but no guidelines for CDI treatment are available in this population. Our primary objective was to evaluate the clinical outcomes in CDI patients with hematological malignancies. Our secondary objectives were to...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2017.07.002
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:Our objective was to estimate the case fatality rates of Zaire, Sudan, and Bundibugyo Ebola species, responsible for sometimes-lethal hemorrhagic fevers. METHODS:We performed a meta-analysis of World Health Organization data on outbreaks of infections due to theses species. RESULTS:Twenty outbreaks, includi...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,meta分析
doi:10.1016/j.medmal.2014.08.005
更新日期:2014-09-01 00:00:00
abstract::Lactobacilli rhamnosus infections are rare and occur in patients with severe conditions causing immunosuppression and/or in those who have received intense antibiotic treatment such as with teicoplanin and vancomycin. We report two cases which occurred within a period of 48 hours, during regression of pancreatitis in ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2007.10.005
更新日期:2008-01-01 00:00:00
abstract::The fight against multi-drug resistant Gram-negative bacilli (MDRGNB), especially extended-spectrum β-lactamase producing Enterobacteriaceae, is about to be lost in our country. The emergence of new resistance mechanisms to carbapenems in these Enterobacteriaceae exposes patients to a risk of treatment failure without...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2014.07.006
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:The increasing resistance of Helicobacter pylori to clarithromycin led to developing new eradication treatment regimens. The objective of our observational study was to determine the proportion of H. pylori strains resistant to clarithromycin in infected patients in Reunion Island and to suggest a first-line ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2016.06.004
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:This study was made to determine the incidence of nosocomial viral gastroenteritis in all children aged 0-4 years, admitted in the Pediatric Hospital over a 3-year period. METHODS:Astrovirus was detected by reverse transcriptase-PCR; routine diagnostic tests for Rotavirus, Adenovirus, and common bacterial pa...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2005.03.006
更新日期:2005-04-01 00:00:00
abstract::Treatment indications for tuberculosis-infection depend on each case, but also on public health policy in each country. This policy usually made at the national level depends on tuberculosis epidemiology of the population concerned and on the country's socio-economic level of development, and more especially of its he...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:
更新日期:2004-08-01 00:00:00
abstract::Over the past 20 years, some Enterobacteriaceae mainly Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis have demonstrated acquisition of plasmids secreting ESBL. CTX-M type ESBL have been isolated worldwide and their incidence has increased dramatically and is still increasing leading to a major therapeu...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2014.03.010
更新日期:2014-09-01 00:00:00
abstract:INTRODUCTION:Persistent high-risk HPV (HR-HPV) infection is associated with a greater risk of cervical cancer. PATIENTS AND METHODS:Statistical data on the prevalence of HR-HPV infections in the Algerian population is lacking. We conducted a prospective study of 300 women aged between 25 and 50 years, screened for cer...
journal_title:Medecine et maladies infectieuses
pub_type: 临床试验,杂志文章
doi:10.1016/j.medmal.2017.05.013
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:Assessing the vaccination coverage rate in Mayotte dispensaries. PATIENTS AND METHODS:Prospective study in three dispensaries from June to July 2019. RESULTS:Of the 162 patients included, 78% (126/162) were natives of the island and 19% (30/162) were from the Comoros Islands. Twenty-three percent (37/162) w...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2020.10.011
更新日期:2020-10-15 00:00:00
abstract:OBJECTIVES:The proper use of antibiotics is a public health priority to preserve their effectiveness. Little data is available on outpatient antibiotic prescriptions, especially in the emergency department. We aimed to assess the quality of outpatient antibiotic prescriptions in our hospital. PATIENTS AND METHODS:Retr...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2016.04.006
更新日期:2016-06-01 00:00:00
abstract:GOAL:This study had for aim to determine the mortality rate and the factors affecting mortality among 70 children admitted for septic shock secondary to a community acquired infection. PATIENTS AND METHODS:A retrospective analysis was made of patients admitted between January 1998 and August 2005, in a pediatric ICU f...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2008.11.002
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to estimate the frequency of methicillin-resistant Staphylococcus aureus (MRSA) strains in the French community and the proportion of Panton-Valentine (PVL)-MRSA. DESIGN:A cross-sectional study was made during a 3-month period in 2003 through a network of private-sector, community-b...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2009.03.007
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:To determine predictive factors of treatment interruption (TI) duration within a cohort of HIV-1 infected patients having stopped their treatment with CD4 above 350 cells per mm(3). DESIGN:Data were collected from computerized medical records. Patients were selected if they were HIV-1 positive, 18 years of a...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2006.01.009
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVE:Improving the use of antimicrobial drugs is a national objective. To this end an evaluation of clinical practice was implemented on prescribed antibiotics in elderly patients, in the Besançon Teaching Hospital. DESIGN:In 2005, a clinical audit compared the adequacy of antibiotic prescriptions to national gui...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2011.02.002
更新日期:2011-06-01 00:00:00
abstract:AIM:The aim of this study was to investigate the phenotypic and genotypic properties of clumping factor- and protein A- negative MRSA. METHODS:Two hundred ninety-four strains were studied. The production of protein A was determined by immunoblotting, clumping factor (CF) and coagulase by conventional tests with rabbit...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medmal.2006.07.006
更新日期:2006-09-01 00:00:00
abstract:UNLABELLED:In France, according to the National Epidemiology Observatory of Bacterial Resistance to Antibiotics, 15.3% of outpatient urinary Escherichia coli isolates were fluoroquinolone-resistant in 2010. This puts to question the relevance of empirical fluoroquinolone therapy for community-acquired acute pyelonephri...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medmal.2014.02.003
更新日期:2014-05-01 00:00:00
abstract::Cet article a du être retiré conformément à la ligne de conduite d'Elsevier concernant le retrait d'articles. Vous pouvez consulter le site (http://www.elsevier.com/locate/withdrawalpolicy) pour de plus amples renseignements. L'éditeur vous prie d'accepter ses excuses pour ce désagrément. ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2008.11.009
更新日期:2008-12-27 00:00:00
abstract:UNLABELLED:Vaccine coverage against hepatitis B virus (HBV) in France has decreased to one of the lowest levels among countries that recommend it, over the last decade. The probable cause was that the vaccine was suspected to induce demyelinating diseases. We studied the factors limiting the use of HBV vaccine amongst ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2011.07.002
更新日期:2011-10-01 00:00:00
abstract:INTRODUCTION:HIV patients have a high rate of infectious complications. Vaccination, though less efficient in case of severe immunosuppression, can prevent some of these infections. Since 2006, new vaccine recommendations have been elaborated in France. We studied the vaccine status of HIV+ patients for influenza, Stre...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medmal.2010.06.005
更新日期:2010-12-01 00:00:00
abstract:INTRODUCTION:Varicella occurring in healthy adults may extend to the lungs. Diagnosing this complication is sometimes difficult because of the discrepancy between imaging and clinical presentation usually reported in this affection. METHOD:The authors report the result of a retrospective study on 106 immunocompetent p...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2008.09.025
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:Our study dealt with antibiotic resistance and serotypes of Pseudomonas aeruginosa strains isolated from immunocompromised patients in the National Bone Marrow Transplant Center of Tunis as well as molecular typing of ceftazidime resistant strains (CAZ-R). DESIGN:We studied a total of 87 non-replicate P. aer...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2005.08.006
更新日期:2005-11-01 00:00:00
abstract::Lyme disease diagnosis is currently based on serology - an indirect diagnostic method - as laboratory cultures are fastidious. The only direct diagnostic method that can be useful with some specimens (cutaneous biopsies or aspiration fluid) is PCR. We aimed to detail the main limitations of serology and PCR testing in...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2018.12.004
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVES:Streptococcus agalactiae (Group B streptococcus) is a major cause of invasive diseases in non-pregnant adults, particularly in the elderly and those with underlying conditions. We describe these conditions and clinical characteristics of patients followed in our teaching hospital. METHODS:We retrospectively...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2007.04.003
更新日期:2007-12-01 00:00:00
abstract:UNLABELLED:Rabies is responsible for 50,000 deaths per year worldwide. Mainland France has been officially freed from rabies in non-flying animals since 2001. METHOD:We wanted to provide an update on the French situation, using published data, and describe possible options since official guidelines are lacking. RESUL...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2014.05.002
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:To assess the proportion of patients meeting the 2010 SPILF-AFSSAPS guiding criteria for Streptococcuspneumoniae in patients consulting at the emergency departments of four French university hospitals for acute community-acquired pneumonia (CAP) suspicion. PATIENTS AND METHODS:The PACSCAN study prospectively...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2020.09.004
更新日期:2020-09-17 00:00:00
abstract:OBJECTIVE:A preliminary analysis of data consistency on different types of bacterial resistance by infection site and causative agents was conducted using the French hospital discharge database (French acronym PMSI) to assess the use of the database in a national cartography tool. MATERIAL AND METHODS:Hospital stays i...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2018.03.007
更新日期:2018-10-01 00:00:00
abstract::Severe sepsis, which is related to a high mortality rate, requires a very specific antibiotic strategy, which must be adapted to each case. The appropriateness of empiric therapy is based on the delay before administration of the molecule, the bacterial resistance profile, and the kinetic and/or dynamic properties of ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2006.02.002
更新日期:2006-06-01 00:00:00