Abstract:
GOAL:This study had for aim to determine the mortality rate and the factors affecting mortality among 70 children admitted for septic shock secondary to a community acquired infection. PATIENTS AND METHODS:A retrospective analysis was made of patients admitted between January 1998 and August 2005, in a pediatric ICU for septic shock secondary to a community-acquired infection. Neonates under 7 days of age were excluded from the study. RESULTS:Seventy cases were included and 32 (45.7 %) of them died. Their average age was 3.8+/-4.2 years and their PRISM during the first 24 hours was 19.2+/-8.4. Sixty-nine children (98.6 %) presented with multivisceral failure and 60 (85.7 %) with more than two deficient organs. The average time between the observation of first hemodynamic disorders and admission to ICU was 9.4+/-11.3 hours. Three independent mortality risk factors were identified: failure of more than two organs on admission (OR, 4.4; 95 % CI [2.1-9.4]), an infusion volume superior to 20ml/kg on the second day of resuscitation (OR, 3.4; 95 CI % [1.1-10.3]), and the use of more than two vasoactive drugs (OR, 3.3; 95 CI % [1.2-9]).
journal_name
Med Mal Infectjournal_title
Medecine et maladies infectieusesauthors
Menif K,Khaldi A,Bouziri A,Kechaou W,Belhadj S,Hamdi A,Kazdaghli K,Benjaballah Ndoi
10.1016/j.medmal.2008.11.002subject
Has Abstractpub_date
2009-12-01 00:00:00pages
896-900issue
12eissn
0399-077Xissn
1769-6690pii
S0399-077X(08)00418-6journal_volume
39pub_type
杂志文章abstract:OBJECTIVES:French reference centers for bone and joint infections (BJI) were implemented from 2009 onwards to improve the management of complex BJIs. This study compared BJI burden before and after the implementation of these reference centers. PATIENTS AND METHODS:BJI hospital stays were selected from the 2008 and 20...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2018.02.004
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVE:Improving the use of antimicrobial drugs is a national objective. To this end an evaluation of clinical practice was implemented on prescribed antibiotics in elderly patients, in the Besançon Teaching Hospital. DESIGN:In 2005, a clinical audit compared the adequacy of antibiotic prescriptions to national gui...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2011.02.002
更新日期:2011-06-01 00:00:00
abstract::The TORO 1 and TORO 2 clinical trials compared the efficacy and safety of enfuvirtide in combination with an optimized background antiretroviral regimen and optimized background regimen alone in HIV-1 infected patients. The patients had had previous treatment with each of the three classes of antiretroviral drugs and ...
journal_title:Medecine et maladies infectieuses
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2004-09-01 00:00:00
abstract::Travellers' diarrhoea represents the most frequent health problem when travelling in developing countries. In most cases it is a self-limited disease. Nonetheless it can cause incapacitation and significant morbidity. It can become persistent in up to 3% of travellers who have suffered from acute diarrhoea in regions ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2007.09.003
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVES:Errors are frequently made in the prescription of antiretroviral medication for hospitalized HIV-infected patients. We had for aim to evaluate the prescription of antiretroviral drug regimens at hospital admission and the impact of a strategy implemented to prevent errors. METHODS:HIV-infected patients mana...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2013.07.006
更新日期:2013-09-01 00:00:00
abstract::Among children, an epidemiologic shift has caused an increase in non-albicans Candida infections and invasive aspergillosis, as well as infections by pathogens that were previously uncommon. These infections are frequent causes of infectious morbidity in immunocompromised children. Treatment options are limited for ch...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/s0399-077x(07)80054-0
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:The long-term impact of treatment strategies proposed by the IDSA guidelines for patients presenting with methicillin-susceptible S. aureus (MSSA) prosthetic joint infection (PJI) is not well-known. PATIENTS AND METHODS:Retrospective (2000-2010) cohort study including patients presenting with MSSA hip or kne...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2017.09.016
更新日期:2018-05-01 00:00:00
abstract::Anti-NMDA-receptor encephalitis has been described only recently among other causes of paraneoplastic and auto-immune limbic encephalitis. Its frequency is probably underestimated. The very characteristic clinical presentation, the severity of symptoms frequently leading to the intensive care unit, the therapeutic imp...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2009.10.013
更新日期:2010-01-01 00:00:00
abstract::For the next decade, COPD will become the third cause of mortality in the world. COPD is mainly due to cigarette smoking and presents different levels of severity according to people, probably linked to environmental and genetic factors, which are not well documented. Recent publications pointed out bacterial bronchia...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2005.12.006
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVES:The Antibiolor network assessed the good use of fluoroquinolones (FQ) in the French Lorraine region by a relevance review. METHODS:At the beginning of 2008, the experts in voluntary hospitals filled out a standard card mentioning the indication, FQ name, route, and duration according to prescriptions in the...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medmal.2009.08.022
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVES:One-stage replacement arthroplasty for treatment of periprosthetic joint infection (PJI) results in similar cure rate than two-stage (around 85-92%), but antibiotic therapy duration is not well established. The aim of this study was to evaluate the efficacy of a short six-week antibiotic course in periprosth...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2020.03.003
更新日期:2020-10-01 00:00:00
abstract::This review concerning the major lower respiratory tract pathogens in France has for aim to describe the epidemiology of resistance to beta-lactams, macrolides, ketolides, and fluoroquinolones especially in Streptococcus pneumoniae and Haemophilus influenzae. It should also provide new insights on the mechanisms of ac...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2006.05.015
更新日期:2006-11-01 00:00:00
abstract:INTRODUCTION:Varicella occurring in healthy adults may extend to the lungs. Diagnosing this complication is sometimes difficult because of the discrepancy between imaging and clinical presentation usually reported in this affection. METHOD:The authors report the result of a retrospective study on 106 immunocompetent p...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2008.09.025
更新日期:2009-02-01 00:00:00
abstract:UNLABELLED:Self-medication with antibiotics is all the more disturbing in developing countries where this type of medication is easily available, and often without any prescription. OBJECTIVES:The authors wanted to assess and describe self-medication with antibiotics and identify the factors and public perception asso...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2009.10.002
更新日期:2010-06-01 00:00:00
abstract::Cet article a du être retiré conformément à la ligne de conduite d'Elsevier concernant le retrait d'articles. Vous pouvez consulter le site (http://www.elsevier.com/locate/withdrawalpolicy) pour de plus amples renseignements. L'éditeur vous prie d'accepter ses excuses pour ce désagrément. ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2008.11.009
更新日期:2008-12-27 00:00:00
abstract:OBJECTIVE:Increasing antimicrobial resistance in bacteria is a major health problem and requires the implementation of stringent policies to optimize the use of antibiotics. DESIGN:In 2003 the authors conducted a study in southwestern French hospitals, using a questionnaire to assess the implementation of antibiotic p...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2005.09.004
更新日期:2005-11-01 00:00:00
abstract::The first successful culture of Tropheryma whipplei made 10 years ago opened the way for identification of the bacterium and the development of many diagnostic tools. Phylogenetic analyses made it possible to classify it among Gram positive bacilli in the family of Actinomycetes, close to other ubiquitous bacteria of ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2009.10.017
更新日期:2010-07-01 00:00:00
abstract::Bartonella henselae is the etiologic agent of the cat scratch disease and in immunocompromised patients, of bacillary angiomatosis and peliosis hepatis. Less often, ocular complications associated with B. henselae infection have been reported in immunocompetent patients and five times in HIV-infected patients. We repo...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2008.06.006
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVES:Temocillin was introduced in 2015 in the French guidelines for the treatment of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae urinary tract infections. Little susceptibility data is available. We investigated the in vitro activity of temocillin against ESBL-producing Enterobacteriaceae...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2018.10.007
更新日期:2019-02-01 00:00:00
abstract::Leptospirosis is a zoonosis found worldwide, the main reservoir of which is the rat. Human infection generally results from exposure to contaminated river or lake water or animals. Around 600 cases are diagnosed per year in France. Half of these cases occur in French overseas territories, where the incidence can be mo...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2012.11.005
更新日期:2013-01-01 00:00:00
abstract::Severe sepsis, which is related to a high mortality rate, requires a very specific antibiotic strategy, which must be adapted to each case. The appropriateness of empiric therapy is based on the delay before administration of the molecule, the bacterial resistance profile, and the kinetic and/or dynamic properties of ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2006.02.002
更新日期:2006-06-01 00:00:00
abstract::Cholera is a bacterial infection, which causes digestive symptoms and massive diarrhoea. It may lead to dehydration and death if appropriate medical management is not rapidly initiated. Most cases of infection by choleric vibrio, however, remain symptom-free or may mimic common gastroenteritis. A review of two cases o...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2006.01.012
更新日期:2006-06-01 00:00:00
abstract:INTRODUCTION:The etiological diagnosis of infectious encephalitis is often not established 48hours after onset. We aimed to review existing literature data before providing management guidelines. METHOD:We performed a literature search on PubMed using filters such as "since 01/01/2000", "human", "adults", "English or ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2017.02.004
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:Assessing the vaccination coverage rate in Mayotte dispensaries. PATIENTS AND METHODS:Prospective study in three dispensaries from June to July 2019. RESULTS:Of the 162 patients included, 78% (126/162) were natives of the island and 19% (30/162) were from the Comoros Islands. Twenty-three percent (37/162) w...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2020.10.011
更新日期:2020-10-15 00:00:00
abstract:OBJECTIVES:The authors had for aim to evaluate the efficacy and tolerance of oral levofloxacin (500 mg once a day during ten days), as a treatment for acute bacterial sinusitis at risk for complications in adult patients. PATIENTS AND METHODS:This was a prospective, multicenter, open, non-comparative, efficacy and tol...
journal_title:Medecine et maladies infectieuses
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.medmal.2005.06.001
更新日期:2005-06-01 00:00:00
abstract::Lyme disease diagnosis is currently based on serology - an indirect diagnostic method - as laboratory cultures are fastidious. The only direct diagnostic method that can be useful with some specimens (cutaneous biopsies or aspiration fluid) is PCR. We aimed to detail the main limitations of serology and PCR testing in...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2018.12.004
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:The increasing resistance of Helicobacter pylori to clarithromycin led to developing new eradication treatment regimens. The objective of our observational study was to determine the proportion of H. pylori strains resistant to clarithromycin in infected patients in Reunion Island and to suggest a first-line ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2016.06.004
更新日期:2016-10-01 00:00:00
abstract::Lactobacilli rhamnosus infections are rare and occur in patients with severe conditions causing immunosuppression and/or in those who have received intense antibiotic treatment such as with teicoplanin and vancomycin. We report two cases which occurred within a period of 48 hours, during regression of pancreatitis in ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2007.10.005
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:This retrospective study was undertaken to assess epidemiological and clinical aspects as well as outcome of tetanus cases in patients over 28 days of age, so as to issue recommendations. PATIENTS AND METHODS:This study included patients admitted to the Fann teaching hospital in Dakar from 2001 to 2003. Age,...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2004.11.003
更新日期:2005-01-01 00:00:00
abstract::Climatic factors (temperature, wind, humidity) and their changes play a major role in the epidemiology of infectious diseases, mainly those vector borne or water-borne. In terms of respiratory tract infections, the role of cold remains controversial, although evident in popular belief: the winter peak is multifactoria...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2008.12.002
更新日期:2009-03-01 00:00:00