[Mortality rates in pediatric septic shock secondary to community-acquired infection: about 70 cases].

Abstract:

GOAL:This study had for aim to determine the mortality rate and the factors affecting mortality among 70 children admitted for septic shock secondary to a community acquired infection. PATIENTS AND METHODS:A retrospective analysis was made of patients admitted between January 1998 and August 2005, in a pediatric ICU for septic shock secondary to a community-acquired infection. Neonates under 7 days of age were excluded from the study. RESULTS:Seventy cases were included and 32 (45.7 %) of them died. Their average age was 3.8+/-4.2 years and their PRISM during the first 24 hours was 19.2+/-8.4. Sixty-nine children (98.6 %) presented with multivisceral failure and 60 (85.7 %) with more than two deficient organs. The average time between the observation of first hemodynamic disorders and admission to ICU was 9.4+/-11.3 hours. Three independent mortality risk factors were identified: failure of more than two organs on admission (OR, 4.4; 95 % CI [2.1-9.4]), an infusion volume superior to 20ml/kg on the second day of resuscitation (OR, 3.4; 95 CI % [1.1-10.3]), and the use of more than two vasoactive drugs (OR, 3.3; 95 CI % [1.2-9]).

journal_name

Med Mal Infect

authors

Menif K,Khaldi A,Bouziri A,Kechaou W,Belhadj S,Hamdi A,Kazdaghli K,Benjaballah N

doi

10.1016/j.medmal.2008.11.002

subject

Has Abstract

pub_date

2009-12-01 00:00:00

pages

896-900

issue

12

eissn

0399-077X

issn

1769-6690

pii

S0399-077X(08)00418-6

journal_volume

39

pub_type

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