Abstract:
:Leptospirosis is a zoonosis found worldwide, the main reservoir of which is the rat. Human infection generally results from exposure to contaminated river or lake water or animals. Around 600 cases are diagnosed per year in France. Half of these cases occur in French overseas territories, where the incidence can be more than 100 times higher than in mainland France. Leptospirosis has been under-diagnosed because of non-specific symptoms, inadequate surveillance system, and lack of readily available quick and simple diagnostic tests. Most cases of leptospirosis are currently detected by PCR amplification of bacterial DNA from the blood during the first week after the onset of symptoms, or by detection of antibodies during the second week of the disease. More than 300 serovars have been identified among leptospires, including serovar Icterohaemorrhagiae, the most frequent in human infections. Leptospirosis remains a major public health issue in many developing countries, one century after discovering the causative agent. Leptospirosis is expected to become more important due to a rapid urbanization in developing countries (slums), global warming, and extreme climatic events (floods).
journal_name
Med Mal Infectjournal_title
Medecine et maladies infectieusesauthors
Picardeau Mdoi
10.1016/j.medmal.2012.11.005subject
Has Abstractpub_date
2013-01-01 00:00:00pages
1-9issue
1eissn
0399-077Xissn
1769-6690pii
S0399-077X(12)00319-8journal_volume
43pub_type
杂志文章,评审abstract:OBJECTIVE:To assess the proportion of patients meeting the 2010 SPILF-AFSSAPS guiding criteria for Streptococcuspneumoniae in patients consulting at the emergency departments of four French university hospitals for acute community-acquired pneumonia (CAP) suspicion. PATIENTS AND METHODS:The PACSCAN study prospectively...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2020.09.004
更新日期:2020-09-17 00:00:00
abstract:OBJECTIVE:We aimed to investigate the prevalence of low bone mineral density (BMD) and associated factors in antiretroviral therapy (ART)-naive HIV-infected young men. METHODS:In this cross-sectional study, dual-energy X-ray absorptiometry (DXA) was used to measure BMD. BMD at the lumbar spine, total hip and femoral n...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2018.02.009
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:Our objective was to estimate the case fatality rates of Zaire, Sudan, and Bundibugyo Ebola species, responsible for sometimes-lethal hemorrhagic fevers. METHODS:We performed a meta-analysis of World Health Organization data on outbreaks of infections due to theses species. RESULTS:Twenty outbreaks, includi...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,meta分析
doi:10.1016/j.medmal.2014.08.005
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:The authors had for objective to assess systemic antifungal treatment for candidemia in non-neutropenic patients, in intensive care units (ICU), and compare the results with French 2004 recommendations. STUDY DESIGN:A retrospective multicenter study (nine ICU in two teaching hospitals) was made. PATIENTS AN...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medmal.2010.06.007
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:Septic arthritis of the facet joint is a rare clinical entity. We report 11 cases of facet joint infections diagnosed in our institution. PATIENTS AND METHOD:Patients were identified via the computerized patients record (PMSI). Their features were collected and compared with published data. RESULTS:The clin...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2015.04.001
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:We aimed to describe the challenge faced by the national reference laboratory to support the national HIV/AIDS response in Madagascar. METHODS:Collaboration between the National Reference Laboratory of Madagascar (NRLM) and foreign partners (a laboratory and an international organization) on the basis of a t...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2016.03.003
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVES:Errors are frequently made in the prescription of antiretroviral medication for hospitalized HIV-infected patients. We had for aim to evaluate the prescription of antiretroviral drug regimens at hospital admission and the impact of a strategy implemented to prevent errors. METHODS:HIV-infected patients mana...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2013.07.006
更新日期:2013-09-01 00:00:00
abstract:INTRODUCTION:Vancomycin is still the cornerstone of antibiotic therapy for patients with suspected or proven invasive methicillin resistant Staphylococcus aureus infections. However, clinical and pharmacodynamic studies underline that appropriate doses depend on the infection site, the patient's weight, his renal funct...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2009.10.004
更新日期:2010-05-01 00:00:00
abstract:INTRODUCTION:The increased risk of a new influenza pandemic has raised awareness of the need for high influenza vaccination rates. OBJECTIVES:This study aims at assessing trends in influenza vaccination coverage from 2001 to 2006 in France, at understanding the drivers and barriers, and to identify vaccination intenti...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2007.11.014
更新日期:2008-03-01 00:00:00
abstract::Cet article a du être retiré conformément à la ligne de conduite d'Elsevier concernant le retrait d'articles. Vous pouvez consulter le site (http://www.elsevier.com/locate/withdrawalpolicy) pour de plus amples renseignements. L'éditeur vous prie d'accepter ses excuses pour ce désagrément. ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2008.11.009
更新日期:2008-12-27 00:00:00
abstract:UNLABELLED:Vaccine coverage against hepatitis B virus (HBV) in France has decreased to one of the lowest levels among countries that recommend it, over the last decade. The probable cause was that the vaccine was suspected to induce demyelinating diseases. We studied the factors limiting the use of HBV vaccine amongst ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2011.07.002
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate the adequacy and the conformity of prescriptions of new systemic antifungal drugs to guidelines and scientific data. PATIENTS AND METHODS:Each prescription of liposomal amphotericin B (lip Amb), voriconazole, and caspofungin made between May 2003 and May 2004 in a teach...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2007.05.009
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVES:Protection of French young infants against pertussis only relies on their relatives' vaccination. The alternative is vaccination of pregnant women against pertussis (cocooning strategy), but this strategy is not yet recommended in France. We assessed the acceptance of this strategy among French postpartum wo...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medmal.2019.09.001
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:Overdiagnosis of lyme borreliosis leads to unnecessary and increasingly common antimicrobial treatments. We aimed to evaluate patients receiving long-term antimicrobial treatment for lyme borreliosis. METHODS:We included patients referred to a Parisian teaching hospital between January 1st, 2014 and June 30...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2020.10.018
更新日期:2020-10-21 00:00:00
abstract:OBJECTIVE:The aim of this study was to analyze the distribution of bacteria responsible for community-acquired meningitis and the pattern of resistance of common species. DESIGN:All bacteriologically confirmed cases of community-acquired meningitis were recorded between 1993 and 2001. RESULTS:Two hundred twenty-four ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2005.10.011
更新日期:2006-02-01 00:00:00
abstract::Lactobacilli rhamnosus infections are rare and occur in patients with severe conditions causing immunosuppression and/or in those who have received intense antibiotic treatment such as with teicoplanin and vancomycin. We report two cases which occurred within a period of 48 hours, during regression of pancreatitis in ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2007.10.005
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:The authors had for aim to assess the conformity of antibiotic prescription with guidelines, for the management of community-acquired pneumonia, in a French University Hospital. DESIGN:This prospective study included adults patients hospitalized for pneumonia over a period of six months. The attending physic...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2010.01.009
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVES:To assess the clinical experience of tigecycline-based salvage therapy in patients presenting with Bone and Joint Infections (BJI). PATIENTS AND METHODS:Multicenter retrospective cohort study in France and Turkey (2007-2014). RESULTS:Thirty-six patients (age 58.2±17.8 years; 21 men) were included. The most...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medmal.2017.09.001
更新日期:2018-02-01 00:00:00
abstract::In children, pneumococcus became the predominant infectious agent, after the routine use of the Hib conjugate vaccine dramatically decreased Haemophilus Influenzae type b prevalence. The incidence of invasive pneumococcal infections (IPI) and of non-invasive infections due to vaccine serotypes (VS) decreased by 80% in...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2013.04.006
更新日期:2013-08-01 00:00:00
abstract::Between 1986 and 2005, 54 patients were hospitalized for rabies in the infectious diseases clinic, with an average of 3 cases a year. The patients came from almost all regions of Senegal, Dakar (11 cases), Thiès (9 cases), and Fatick (9 cases). They were native of rural and suburban zones. The median age was 19 years ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2007.01.010
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVES:French reference centers for bone and joint infections (BJI) were implemented from 2009 onwards to improve the management of complex BJIs. This study compared BJI burden before and after the implementation of these reference centers. PATIENTS AND METHODS:BJI hospital stays were selected from the 2008 and 20...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2018.02.004
更新日期:2018-06-01 00:00:00
abstract:INTRODUCTION:Persistent high-risk HPV (HR-HPV) infection is associated with a greater risk of cervical cancer. PATIENTS AND METHODS:Statistical data on the prevalence of HR-HPV infections in the Algerian population is lacking. We conducted a prospective study of 300 women aged between 25 and 50 years, screened for cer...
journal_title:Medecine et maladies infectieuses
pub_type: 临床试验,杂志文章
doi:10.1016/j.medmal.2017.05.013
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:The proper use of antibiotics is a public health priority to preserve their effectiveness. Little data is available on outpatient antibiotic prescriptions, especially in the emergency department. We aimed to assess the quality of outpatient antibiotic prescriptions in our hospital. PATIENTS AND METHODS:Retr...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2016.04.006
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:The authors had for objective to describe patients with confirmed influenza A(H1N1)pdm09 admitted to an intensive care unit (ICU) in a university hospital and to identify risk factors correlated with the severity of the disease. DESIGN:A prospective study was conducted in an university hospital during the A(...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2013.01.016
更新日期:2013-02-01 00:00:00
abstract::Twenty people died of rabies in France between 1970 and 2003 (compared to 55,000 yearly worldwide), 80% on returning from Africa. Dogs were the contaminating animals in 90% of the cases and children were the most common victims. The last instance of rabies in a native French animal was reported in 1998. However the il...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2004.07.031
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to estimate the frequency of methicillin-resistant Staphylococcus aureus (MRSA) strains in the French community and the proportion of Panton-Valentine (PVL)-MRSA. DESIGN:A cross-sectional study was made during a 3-month period in 2003 through a network of private-sector, community-b...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2009.03.007
更新日期:2009-05-01 00:00:00
abstract:INTRODUCTION:The etiological diagnosis of infectious encephalitis is often not established 48hours after onset. We aimed to review existing literature data before providing management guidelines. METHOD:We performed a literature search on PubMed using filters such as "since 01/01/2000", "human", "adults", "English or ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2017.02.004
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVES:Temocillin was introduced in 2015 in the French guidelines for the treatment of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae urinary tract infections. Little susceptibility data is available. We investigated the in vitro activity of temocillin against ESBL-producing Enterobacteriaceae...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2018.10.007
更新日期:2019-02-01 00:00:00
abstract:INTRODUCTION:Nosocomial infections are a matter of concern in surgical wards. Their incidence is constantly increasing, especially among immunocompromised patients who are vulnerable to colonization by opportunistic pathogens such as Staphylococcus aureus. The bacterium accumulates resistance mechanisms against antibio...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2011.09.010
更新日期:2011-12-01 00:00:00
abstract::Cholera is a bacterial infection, which causes digestive symptoms and massive diarrhoea. It may lead to dehydration and death if appropriate medical management is not rapidly initiated. Most cases of infection by choleric vibrio, however, remain symptom-free or may mimic common gastroenteritis. A review of two cases o...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2006.01.012
更新日期:2006-06-01 00:00:00