Abstract：
OBJECTIVE:The aim of this study was to analyze the distribution of bacteria responsible for community-acquired meningitis and the pattern of resistance of common species. DESIGN:All bacteriologically confirmed cases of community-acquired meningitis were recorded between 1993 and 2001. RESULTS:Two hundred twenty-four cases of bacterial meningitis were recorded. The most frequent species were Haemophilus influenzae and Streptococcus pneumoniae followed by Neisseria meningitidis with respectively 37.1%, 32.1%, and 10.7% of cases. The yearly distribution of these bacteria did not show any epidemic peak. Enterobacteria and group B Streptococcus were the most frequently identified pathogens in neonatal meningitis. H. influenzae was the predominant microorganism in children between one month and five years of age, (66.4%) followed by S. pneumoniae (23.5%). S. pneumoniae was the predominant bacteria responsible fore more than half of the cases over five years of age. 28.8% of H. influenzae strains produced beta-lactamase. 27.2% of S. pneumoniae strains were less susceptible to penicillin. Resistance rates for amoxicillin and cefotaxime were respectively 10.6% and 7.5%. Only one strain of N. meningitidis (4.2%) presented with a decreased susceptibility to penicillin. CONCLUSIONS:In our study, H. influenzae and S. pneumoniae were the main microorganisms responsible for community-acquired meningitis. High resistance rates were found for these bacteria: 28.8% of H. influenzae to ampicillin and 27.2% of S. pneumoniae to penicillin.
journal_name
Med Mal Infectjournal_title
Medecine et maladies infectieusesauthors
Maalej SM,Kassis M,Rhimi FM,Damak J,Hammami Adoi
10.1016/j.medmal.2005.10.011keywords:
subject
Has Abstractpub_date
2006-02-01 00:00:00pages
105-10issue
2eissn
0399-077Xissn
1769-6690pii
S0399-077X(05)00353-7journal_volume
36pub_type
杂志文章abstract：INTRODUCTION:An increase of syphilis cases has been recorded in the past few decades, especially among HIV-infected patients. These patients often present with concomitant primary and secondary lesions or extensive presentations of syphilis. OBJECTIVE:Our goal was to compare alternative regimens to the recommended pen...
journal_title：Medecine et maladies infectieuses
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journal_title：Medecine et maladies infectieuses
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abstract：:The TORO 1 and TORO 2 clinical trials compared the efficacy and safety of enfuvirtide in combination with an optimized background antiretroviral regimen and optimized background regimen alone in HIV-1 infected patients. The patients had had previous treatment with each of the three classes of antiretroviral drugs and ...
journal_title：Medecine et maladies infectieuses
pub_type： 临床试验,杂志文章,随机对照试验
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abstract：:Among children, an epidemiologic shift has caused an increase in non-albicans Candida infections and invasive aspergillosis, as well as infections by pathogens that were previously uncommon. These infections are frequent causes of infectious morbidity in immunocompromised children. Treatment options are limited for ch...
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abstract：OBJECTIVE:Assessing the vaccination coverage rate in Mayotte dispensaries. PATIENTS AND METHODS:Prospective study in three dispensaries from June to July 2019. RESULTS:Of the 162 patients included, 78% (126/162) were natives of the island and 19% (30/162) were from the Comoros Islands. Twenty-three percent (37/162) w...
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更新日期：2020-10-15 00:00:00
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doi：10.1016/j.medmal.2016.03.003
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journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2008.12.002
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pub_type： 杂志文章,meta分析
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更新日期：2014-09-01 00:00:00
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abstract：:Leptospirosis is a zoonosis found worldwide, the main reservoir of which is the rat. Human infection generally results from exposure to contaminated river or lake water or animals. Around 600 cases are diagnosed per year in France. Half of these cases occur in French overseas territories, where the incidence can be mo...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2012.11.005
更新日期：2013-01-01 00:00:00
abstract：:We report a fatal case of Chromobacterium violaceum septicemia in a 42-year-old farm worker living in the French West Indies. The bacteria found in the muddy soil and the stagnant water of tropical and subtropical regions is rarely a source of human infection. ...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2006.08.004
更新日期：2007-09-01 00:00:00
abstract：:Anti-NMDA-receptor encephalitis has been described only recently among other causes of paraneoplastic and auto-immune limbic encephalitis. Its frequency is probably underestimated. The very characteristic clinical presentation, the severity of symptoms frequently leading to the intensive care unit, the therapeutic imp...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2009.10.013
更新日期：2010-01-01 00:00:00
abstract：INTRODUCTION:Pneumococcal infections are a major public health problem because of the virulence of this bacterium and its ability to develop resistance. MATERIAL AND METHOD:Two hundred and ninety-four strains of Streptococcus pneumoniae were isolated from sterile (56.8%) and non-sterile samples (43.2%), from January 2...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2011.12.001
更新日期：2012-02-01 00:00:00
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journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2010.04.006
更新日期：2010-11-01 00:00:00
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journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2008.11.002
更新日期：2009-12-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.medmal.2013.06.015
更新日期：2013-08-01 00:00:00
abstract：:We report a case of osteitis in a 46-year-old patient, caused by Pseudomonas stutzeri following an open fracture of the left femur. The patient was treated with 1g ceftazidime every 8 hours for two weeks combined with 160 mg/day of amikacin for 10 days. A second-line ofloxacin oral treatment at 400 mg/day was then giv...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2006.07.007
更新日期：2006-10-01 00:00:00
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journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2006.01.009
更新日期：2006-06-01 00:00:00
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journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2009.02.010
更新日期：2009-12-01 00:00:00
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journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2008.03.004
更新日期：2008-05-01 00:00:00
abstract：OBJECTIVES:This study had for aim to identify the clinical status and the level of immuno-deficiency of HIV-infected patients on their first visit. METHODS:One hundred and thirty-six HIV+ patients were prospectively evaluated from November 1, 2001 to May 31, 2002. RESULTS:One hundred and thirty-four were infected wit...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,多中心研究
doi：10.1016/j.medmal.2004.02.007
更新日期：2004-05-01 00:00:00
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journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2016.03.008
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVE:Pneumocystis pneumonia (PCP) is now predominantly observed in immunosuppressed non-HIV-infected patients. The sensitivity of the PCR is here higher than direct examination (DE) of respiratory secretions because the infection is caused by a lower inoculum of Pneumocystis jirovecii (P. jirovecii). The objective...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2018.04.396
更新日期：2018-10-01 00:00:00
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journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2007.03.006
更新日期：2007-11-01 00:00:00
abstract：OBJECTIVE:Improving the use of antimicrobial drugs is a national objective. To this end an evaluation of clinical practice was implemented on prescribed antibiotics in elderly patients, in the Besançon Teaching Hospital. DESIGN:In 2005, a clinical audit compared the adequacy of antibiotic prescriptions to national gui...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2011.02.002
更新日期：2011-06-01 00:00:00
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journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2020.09.004
更新日期：2020-09-17 00:00:00
abstract：UNLABELLED:In France, according to the National Epidemiology Observatory of Bacterial Resistance to Antibiotics, 15.3% of outpatient urinary Escherichia coli isolates were fluoroquinolone-resistant in 2010. This puts to question the relevance of empirical fluoroquinolone therapy for community-acquired acute pyelonephri...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,多中心研究
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更新日期：2014-05-01 00:00:00
abstract：OBJECTIVES:This descriptive study had for objective to describe the epidemiological, clinical, therapeutic, and evolutionary aspects of the association cholera and pregnancy during the cholera epidemic in Senegal in 2004 and 2005. MATERIAL AND METHOD:We analyzed the files of pregnant women admitted in the infectious d...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2007.05.010
更新日期：2007-12-01 00:00:00
