Abstract：
:Among children, an epidemiologic shift has caused an increase in non-albicans Candida infections and invasive aspergillosis, as well as infections by pathogens that were previously uncommon. These infections are frequent causes of infectious morbidity in immunocompromised children. Treatment options are limited for children. When choosing a therapy, it is important to consider pivotal clinical trial data, available pediatric pharmacokinetic profiles, safety and drug interactions profiles, and species-dependent susceptibilities. For most infections, the best initial treatment is still unassessed. Caspofungin is not yet approved for pediatric use, but an ongoing clinical program on this field gives promising results.
journal_name
Med Mal Infectjournal_title
Medecine et maladies infectieusesauthors
Groll Adoi
10.1016/s0399-077x(07)80054-0subject
Has Abstractpub_date
2007-01-01 00:00:00pages
12-3eissn
0399-077Xissn
1769-6690pii
S0399-077X(07)80054-0journal_volume
37 Suppl 2pub_type
杂志文章,评审abstract：:Lyme borreliosis is transmitted en France by the tick Ixodes ricinus, endemic in metropolitan France. In the absence of vaccine licensed for use in humans, primary prevention mostly relies on mechanical protection (clothes covering most parts of the body) that may be completed by chemical protection (repulsives). Seco...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,实务指引,评审
doi：10.1016/j.medmal.2019.04.381
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVES:The proper use of antibiotics is a public health priority to preserve their effectiveness. Little data is available on outpatient antibiotic prescriptions, especially in the emergency department. We aimed to assess the quality of outpatient antibiotic prescriptions in our hospital. PATIENTS AND METHODS:Retr...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2016.04.006
更新日期：2016-06-01 00:00:00
abstract：INTRODUCTION:No therapy has yet proven effective in COVID-19. Tocilizumab (TCZ) in patients with severe COVID-19 could be an effective treatment. METHOD:We conducted a retrospective case-control study in the Nord Franche-Comté Hospital, France. We compared the outcome of patients treated with TCZ and patients without ...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2020.05.001
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVES:Enterobacter cloacae prosthetic joint infections (PJI) are rare and poorly documented. PATIENTS AND METHODS:We conducted a retrospective and monocentric study in an orthopedic unit supporting complex bone and joint infections. Between 2012 and 2016 we collected background, clinical, biological, and microbio...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2018.12.002
更新日期：2019-10-01 00:00:00
abstract：:Tuberculous arthritis is rare and the diagnosis may be confused with inflammatory arthritis. Only few cases, explored by MRI, have been reported in the literature. We report 3 cases of tuberculous arthritis of the knee revealed by insidious pain. The abnormalities revealed by MRI suggested tuberculosis. Diagnosis was ...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2006.10.006
更新日期：2007-09-01 00:00:00
abstract：OBJECTIVE:Chlamydophila pneumoniae is a common agent of respiratory infections. Severe acute neurological infections are very infrequently linked to this bacterium. We report such a case and give a rapid overview of published cases of acute encephalitis occurring after a respiratory infection due to C. pneumoniae. PAT...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2013.06.015
更新日期：2013-08-01 00:00:00
abstract：OBJECTIVES:To report a case of septic arthritis due to H. parainfluenzae and to review the clinical and microbiological characteristics of published case patients. PATIENTS AND METHODS:Data was collected on age, sex, infection localization, underlying risk factors, symptom onset-diagnosis interval, analytical findings...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2017.08.002
更新日期：2017-12-01 00:00:00
abstract：:The variola virus was the first biological agent to be used as a military weapon. It is considered as one of the main agents that could potentially be used in the context of bioterrorism. Smallpox was declared eradicated in 1980. So, in case of a confirmed or suspected case of smallpox, a deliberate, intentional origi...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2003.09.009
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVES:This study had for aim to identify the clinical status and the level of immuno-deficiency of HIV-infected patients on their first visit. METHODS:One hundred and thirty-six HIV+ patients were prospectively evaluated from November 1, 2001 to May 31, 2002. RESULTS:One hundred and thirty-four were infected wit...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,多中心研究
doi：10.1016/j.medmal.2004.02.007
更新日期：2004-05-01 00:00:00
abstract：OBJECTIVE:Vaccine hesitancy is a growing and threatening trend, increasing the risk of disease outbreaks and potentially defeating health authorities' strategies. We aimed to describe the significant role of social networks and the Internet on vaccine hesitancy, and more generally on vaccine attitudes and behaviors. M...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2016.02.002
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVES:The authors had for aim to assess the inter- and intra-individual variability of teicoplanin pharmacokinetic parameters in geriatric patients. METHODS:A cohort of 90 geriatric patients, treated with teicoplanin, was used to build two models describing the pharmacokinetics of teicoplanin, at the beginning an...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2013.05.008
更新日期：2013-07-01 00:00:00
abstract：OBJECTIVES:One-stage replacement arthroplasty for treatment of periprosthetic joint infection (PJI) results in similar cure rate than two-stage (around 85-92%), but antibiotic therapy duration is not well established. The aim of this study was to evaluate the efficacy of a short six-week antibiotic course in periprosth...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2020.03.003
更新日期：2020-10-01 00:00:00
abstract：INTRODUCTION:The etiological diagnosis of infectious encephalitis is often not established 48hours after onset. We aimed to review existing literature data before providing management guidelines. METHOD:We performed a literature search on PubMed using filters such as "since 01/01/2000", "human", "adults", "English or ...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2017.02.004
更新日期：2017-05-01 00:00:00
abstract：:Anti-NMDA-receptor encephalitis has been described only recently among other causes of paraneoplastic and auto-immune limbic encephalitis. Its frequency is probably underestimated. The very characteristic clinical presentation, the severity of symptoms frequently leading to the intensive care unit, the therapeutic imp...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2009.10.013
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVES:This prospective study had for aim to determine the frequency and characteristics of cardiovascular events in the course of tetanus. PATIENTS AND METHODS:From September to December 2002, we studied all patients over 4 years of age presenting with tetanus without any documented underlying disease. RESULTS:T...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2005.09.005
更新日期：2005-09-01 00:00:00
abstract：OBJECTIVES:Temocillin was introduced in 2015 in the French guidelines for the treatment of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae urinary tract infections. Little susceptibility data is available. We investigated the in vitro activity of temocillin against ESBL-producing Enterobacteriaceae...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2018.10.007
更新日期：2019-02-01 00:00:00
abstract：:Clostridium difficile is an anaerobic spore-forming Gram-positive bacillus recognized as an evolving international health problem. Metronidazole and vancomycin were - until recently - the only drugs available to treat C. difficile infection (CDI). Better knowledge of the pathophysiology and the development of new drug...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2017.10.009
更新日期：2018-02-01 00:00:00
abstract：INTRODUCTION:Acinetobacter baumannii is a ubiquitous pathogen resistant to desiccation and responsible for healthcare-associated infections (HAI), especially in intensive care units (ICU) where it is responsible for 5-10% of HAIs. An A. baumannii outbreak occurred in the ICU of the University Hospital of Angers, France...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2017.06.003
更新日期：2017-10-01 00:00:00
abstract：GOAL:This study had for aim to determine the mortality rate and the factors affecting mortality among 70 children admitted for septic shock secondary to a community acquired infection. PATIENTS AND METHODS:A retrospective analysis was made of patients admitted between January 1998 and August 2005, in a pediatric ICU f...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2008.11.002
更新日期：2009-12-01 00:00:00
abstract：:Twenty people died of rabies in France between 1970 and 2003 (compared to 55,000 yearly worldwide), 80% on returning from Africa. Dogs were the contaminating animals in 90% of the cases and children were the most common victims. The last instance of rabies in a native French animal was reported in 1998. However the il...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2004.07.031
更新日期：2004-12-01 00:00:00
abstract：OBJECTIVE:To study the efficacy and safety of micafungin for prophylaxis of invasive fungal infections in patients undergoing induction chemotherapy for acute myeloid leukemia. PATIENTS AND METHODS:A prospective observational single-center study of 41 patients from the hematology department between May 2012 and April ...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2016.03.008
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVE:This study was made to determine the incidence of nosocomial viral gastroenteritis in all children aged 0-4 years, admitted in the Pediatric Hospital over a 3-year period. METHODS:Astrovirus was detected by reverse transcriptase-PCR; routine diagnostic tests for Rotavirus, Adenovirus, and common bacterial pa...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2005.03.006
更新日期：2005-04-01 00:00:00
abstract：:The aim of this review was to describe the current knowledge of Legionnaires' disease (LD) illustrated by the epidemiological situation in France in 2013. LD is a severe pneumonia commonly caused by Legionella pneumophila serogroup 1. The diagnosis is usually based on the urinary antigen test. This rapid method reduce...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2015.01.015
更新日期：2015-03-01 00:00:00
abstract：:For the next decade, COPD will become the third cause of mortality in the world. COPD is mainly due to cigarette smoking and presents different levels of severity according to people, probably linked to environmental and genetic factors, which are not well documented. Recent publications pointed out bacterial bronchia...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2005.12.006
更新日期：2006-05-01 00:00:00
abstract：OBJECTIVE:Pneumocystis pneumonia (PCP) is now predominantly observed in immunosuppressed non-HIV-infected patients. The sensitivity of the PCR is here higher than direct examination (DE) of respiratory secretions because the infection is caused by a lower inoculum of Pneumocystis jirovecii (P. jirovecii). The objective...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2018.04.396
更新日期：2018-10-01 00:00:00
abstract：OBJECTIVES:French reference centers for bone and joint infections (BJI) were implemented from 2009 onwards to improve the management of complex BJIs. This study compared BJI burden before and after the implementation of these reference centers. PATIENTS AND METHODS:BJI hospital stays were selected from the 2008 and 20...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2018.02.004
更新日期：2018-06-01 00:00:00
abstract：:Urinary tract infections (UTIs) in patients with neurogenic bladder are a major public health issue due to their high incidence and major consequences. Despite their frequency and potential severity, their physiopathology and management are poorly known. We provide a narrative literature review on the epidemiology, ph...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2019.02.006
更新日期：2019-10-01 00:00:00
abstract：OBJECTIVES:Adults with hematological malignancies are at high-risk of Clostridium difficile infection (CDI), but no guidelines for CDI treatment are available in this population. Our primary objective was to evaluate the clinical outcomes in CDI patients with hematological malignancies. Our secondary objectives were to...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2017.07.002
更新日期：2017-12-01 00:00:00
abstract：:This review concerning the major lower respiratory tract pathogens in France has for aim to describe the epidemiology of resistance to beta-lactams, macrolides, ketolides, and fluoroquinolones especially in Streptococcus pneumoniae and Haemophilus influenzae. It should also provide new insights on the mechanisms of ac...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2006.05.015
更新日期：2006-11-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to analyze the distribution of bacteria responsible for community-acquired meningitis and the pattern of resistance of common species. DESIGN:All bacteriologically confirmed cases of community-acquired meningitis were recorded between 1993 and 2001. RESULTS:Two hundred twenty-four ...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2005.10.011
更新日期：2006-02-01 00:00:00
