Abstract：
INTRODUCTION:Acinetobacter baumannii is a ubiquitous pathogen resistant to desiccation and responsible for healthcare-associated infections (HAI), especially in intensive care units (ICU) where it is responsible for 5-10% of HAIs. An A. baumannii outbreak occurred in the ICU of the University Hospital of Angers, France. OBJECTIVES:To describe the A. baumannii outbreak and to evaluate the control measures taken. The secondary objective was to evaluate the impact of the electronic alert system on the incidence of multidrug resistance to antibiotics. METHODS:We performed a descriptive study of A. baumannii carriers during the outbreak. Case contacts and carriers were described using the epidemic curve and a case synopsis table. RESULTS:From August 2011 to September 2013, 49 patients presenting with an extended-spectrum beta-lactamase-producing A. baumannii infection were identified: thirty-four were colonized and 15 were infected. No death was due to the outbreak. Measures taken were: geographical and technical isolation of patients, dedicated team implementation, contact precaution implementation including hand hygiene measures, appropriate use of gloves, and reinforcement of bio-cleaning procedures. CONCLUSION:Some patients were re-admitted to hospital while still being carriers; this could explain epidemic peaks. The immersion mission of the hygiene nurse contributed to answering healthcare workers' queries and led to a better cooperation between the ICU and the hygiene team.
journal_name
Med Mal Infectjournal_title
Medecine et maladies infectieusesauthors
Tanguy M,Kouatchet A,Tanguy B,Pichard É,Fanello S,Joly-Guillou MLdoi
10.1016/j.medmal.2017.06.003subject
Has Abstractpub_date
2017-10-01 00:00:00pages
409-414issue
6eissn
0399-077Xissn
1769-6690pii
S0399-077X(17)30684-4journal_volume
47pub_type
杂志文章abstract：INTRODUCTION:No therapy has yet proven effective in COVID-19. Tocilizumab (TCZ) in patients with severe COVID-19 could be an effective treatment. METHOD:We conducted a retrospective case-control study in the Nord Franche-Comté Hospital, France. We compared the outcome of patients treated with TCZ and patients without ...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2020.05.001
更新日期：2020-08-01 00:00:00
abstract：GOAL:This study had for aim to determine the mortality rate and the factors affecting mortality among 70 children admitted for septic shock secondary to a community acquired infection. PATIENTS AND METHODS:A retrospective analysis was made of patients admitted between January 1998 and August 2005, in a pediatric ICU f...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2008.11.002
更新日期：2009-12-01 00:00:00
abstract：OBJECTIVE:Assessing the vaccination coverage rate in Mayotte dispensaries. PATIENTS AND METHODS:Prospective study in three dispensaries from June to July 2019. RESULTS:Of the 162 patients included, 78% (126/162) were natives of the island and 19% (30/162) were from the Comoros Islands. Twenty-three percent (37/162) w...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2020.10.011
更新日期：2020-10-15 00:00:00
abstract：:HHV-8 belongs to the herpesviridae family, to the gammaherpesvirinae subfamily, and to the rhadinovirus genus. Whereas several viral homologues exist in non human primates, HHV-8 is the only rhadinovirus known in human. HHV-8 is mainly the etiological agent of the four clinico-epidemiological forms of Kaposi's sarcoma...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2005.02.009
更新日期：2005-05-01 00:00:00
abstract：INTRODUCTION:An increase of syphilis cases has been recorded in the past few decades, especially among HIV-infected patients. These patients often present with concomitant primary and secondary lesions or extensive presentations of syphilis. OBJECTIVE:Our goal was to compare alternative regimens to the recommended pen...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2011.10.003
更新日期：2012-01-01 00:00:00
abstract：:Urinary tract infections (UTIs) in patients with neurogenic bladder are a major public health issue due to their high incidence and major consequences. Despite their frequency and potential severity, their physiopathology and management are poorly known. We provide a narrative literature review on the epidemiology, ph...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2019.02.006
更新日期：2019-10-01 00:00:00
abstract：OBJECTIVES:This study had for aim to identify the clinical status and the level of immuno-deficiency of HIV-infected patients on their first visit. METHODS:One hundred and thirty-six HIV+ patients were prospectively evaluated from November 1, 2001 to May 31, 2002. RESULTS:One hundred and thirty-four were infected wit...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,多中心研究
doi：10.1016/j.medmal.2004.02.007
更新日期：2004-05-01 00:00:00
abstract：OBJECTIVE:This study was made to determine the incidence of nosocomial viral gastroenteritis in all children aged 0-4 years, admitted in the Pediatric Hospital over a 3-year period. METHODS:Astrovirus was detected by reverse transcriptase-PCR; routine diagnostic tests for Rotavirus, Adenovirus, and common bacterial pa...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2005.03.006
更新日期：2005-04-01 00:00:00
abstract：INTRODUCTION:Pneumococcal infections are a major public health problem because of the virulence of this bacterium and its ability to develop resistance. MATERIAL AND METHOD:Two hundred and ninety-four strains of Streptococcus pneumoniae were isolated from sterile (56.8%) and non-sterile samples (43.2%), from January 2...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2011.12.001
更新日期：2012-02-01 00:00:00
abstract：UNLABELLED:Self-medication with antibiotics is all the more disturbing in developing countries where this type of medication is easily available, and often without any prescription. OBJECTIVES:The authors wanted to assess and describe self-medication with antibiotics and identify the factors and public perception asso...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2009.10.002
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVES:We had for aim to assess antibiotic consumption and to better understand their use in nursing homes so as to target messages on relevant practice procedures sent to prescribers. DESIGN:The MedQual network asked nursing homes with in-house pharmacies to participate in a retrospective collection of yearly ant...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2015.05.006
更新日期：2015-08-01 00:00:00
abstract：:Any person travelling in countries where yellow fever (YF) is endemic and without presenting contra-indication for the vaccination against YF may be vaccinated. This vaccination can very rarely induce a potentially lethal neurotropic or viscerotropic disease. In severely immunodeficient patients, the vaccination is co...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2008.06.031
更新日期：2008-10-01 00:00:00
abstract：OBJECTIVE:Improving the use of antimicrobial drugs is a national objective. To this end an evaluation of clinical practice was implemented on prescribed antibiotics in elderly patients, in the Besançon Teaching Hospital. DESIGN:In 2005, a clinical audit compared the adequacy of antibiotic prescriptions to national gui...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2011.02.002
更新日期：2011-06-01 00:00:00
abstract：:This review concerning the major lower respiratory tract pathogens in France has for aim to describe the epidemiology of resistance to beta-lactams, macrolides, ketolides, and fluoroquinolones especially in Streptococcus pneumoniae and Haemophilus influenzae. It should also provide new insights on the mechanisms of ac...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2006.05.015
更新日期：2006-11-01 00:00:00
abstract：:The coronavirus disease 2019 (COVID-19) was first reported in the city of Wuhan, China. The disease rapidly spread to the rest of China, to Southern-East Asia, then to Europe, America, and on to the rest of the world. COVID-19 is associated with a betacoronavirus named SARS-CoV-2. The virus penetrates the organism thr...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2020.09.012
更新日期：2020-11-01 00:00:00
abstract：INTRODUCTION:Persistent high-risk HPV (HR-HPV) infection is associated with a greater risk of cervical cancer. PATIENTS AND METHODS:Statistical data on the prevalence of HR-HPV infections in the Algerian population is lacking. We conducted a prospective study of 300 women aged between 25 and 50 years, screened for cer...
journal_title：Medecine et maladies infectieuses
pub_type： 临床试验,杂志文章
doi：10.1016/j.medmal.2017.05.013
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVES:Temocillin was introduced in 2015 in the French guidelines for the treatment of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae urinary tract infections. Little susceptibility data is available. We investigated the in vitro activity of temocillin against ESBL-producing Enterobacteriaceae...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2018.10.007
更新日期：2019-02-01 00:00:00
abstract：OBJECTIVE:The authors had for aim to describe the epidemiological, clinical, and bacteriological aspects and outcome of pediatric Salmonella enterica, Salmonella septicemia, over the last 10 years. PATIENTS AND METHODS:We analyzed the case history of 132 patients hospitalized for Salmonellasepticemia (positive blood c...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2007.08.002
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVES:Errors are frequently made in the prescription of antiretroviral medication for hospitalized HIV-infected patients. We had for aim to evaluate the prescription of antiretroviral drug regimens at hospital admission and the impact of a strategy implemented to prevent errors. METHODS:HIV-infected patients mana...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2013.07.006
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVES:Streptococcus agalactiae (Group B streptococcus) is a major cause of invasive diseases in non-pregnant adults, particularly in the elderly and those with underlying conditions. We describe these conditions and clinical characteristics of patients followed in our teaching hospital. METHODS:We retrospectively...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2007.04.003
更新日期：2007-12-01 00:00:00
abstract：OBJECTIVES:The Antibiolor network assessed the good use of fluoroquinolones (FQ) in the French Lorraine region by a relevance review. METHODS:At the beginning of 2008, the experts in voluntary hospitals filled out a standard card mentioning the indication, FQ name, route, and duration according to prescriptions in the...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,多中心研究
doi：10.1016/j.medmal.2009.08.022
更新日期：2010-02-01 00:00:00
abstract：OBJECTIVE:To assess the proportion of patients meeting the 2010 SPILF-AFSSAPS guiding criteria for Streptococcuspneumoniae in patients consulting at the emergency departments of four French university hospitals for acute community-acquired pneumonia (CAP) suspicion. PATIENTS AND METHODS:The PACSCAN study prospectively...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2020.09.004
更新日期：2020-09-17 00:00:00
abstract：:The first successful culture of Tropheryma whipplei made 10 years ago opened the way for identification of the bacterium and the development of many diagnostic tools. Phylogenetic analyses made it possible to classify it among Gram positive bacilli in the family of Actinomycetes, close to other ubiquitous bacteria of ...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2009.10.017
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVE:Although urinary tract infections are the second leading cause of infections among patients aged above 65 years, data on bacterial epidemiology of urinary specimens in these patients is scarce. Our aim was to describe the main bacterial species found at significant levels in urine specimens of the elderly and...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2017.03.002
更新日期：2017-06-01 00:00:00
abstract：:The fight against multi-drug resistant Gram-negative bacilli (MDRGNB), especially extended-spectrum β-lactamase producing Enterobacteriaceae, is about to be lost in our country. The emergence of new resistance mechanisms to carbapenems in these Enterobacteriaceae exposes patients to a risk of treatment failure without...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,评审
doi：10.1016/j.medmal.2014.07.006
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVE:We performed a prospective multicenter study to assess dryness and irritation of hands of staff in care facilities, and to show that disinfection with alcohol-based hand rub is better tolerated than classic hand washing with mild soap. METHOD:Dryness and irritation were self-evaluated by volunteers and heter...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,多中心研究
doi：10.1016/j.medmal.2010.09.021
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVE:This retrospective study was undertaken to assess epidemiological and clinical aspects as well as outcome of tetanus cases in patients over 28 days of age, so as to issue recommendations. PATIENTS AND METHODS:This study included patients admitted to the Fann teaching hospital in Dakar from 2001 to 2003. Age,...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2004.11.003
更新日期：2005-01-01 00:00:00
abstract：AIM:The aim of this study was to investigate the phenotypic and genotypic properties of clumping factor- and protein A- negative MRSA. METHODS:Two hundred ninety-four strains were studied. The production of protein A was determined by immunoblotting, clumping factor (CF) and coagulase by conventional tests with rabbit...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章,多中心研究
doi：10.1016/j.medmal.2006.07.006
更新日期：2006-09-01 00:00:00
abstract：OBJECTIVE:To determine predictive factors of treatment interruption (TI) duration within a cohort of HIV-1 infected patients having stopped their treatment with CD4 above 350 cells per mm(3). DESIGN:Data were collected from computerized medical records. Patients were selected if they were HIV-1 positive, 18 years of a...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2006.01.009
更新日期：2006-06-01 00:00:00
abstract：OBJECTIVES:This descriptive study had for objective to describe the epidemiological, clinical, therapeutic, and evolutionary aspects of the association cholera and pregnancy during the cholera epidemic in Senegal in 2004 and 2005. MATERIAL AND METHOD:We analyzed the files of pregnant women admitted in the infectious d...
journal_title：Medecine et maladies infectieuses
pub_type： 杂志文章
doi：10.1016/j.medmal.2007.05.010
更新日期：2007-12-01 00:00:00
