Abstract：
OBJECTIVES:Streptococcus agalactiae (Group B streptococcus) is a major cause of invasive diseases in non-pregnant adults, particularly in the elderly and those with underlying conditions. We describe these conditions and clinical characteristics of patients followed in our teaching hospital. METHODS:We retrospectively reviewed clinical records of 64 patients with S. agalactiae-related invasive infection, hospitalized between January 1997 and January 2006. RESULTS:The mean age of patients was 59 (+/-17 years). The H:F sex ratio was 1.06. At least one underlying condition was found in 90.6%. Diabetes mellitus (43.7%), peripheral vascular disease (34.4%), myocardial ischemia (20.3%) and malignant neoplasms (20.3%) were among the most frequent conditions. The mean index of comorbidity (Charlson) was 2.5 (+/-2). Common clinical manifestations included infection of the urinary tract (32.8%), skin and soft-tissue (25%), and osteoarthritis (21.9%). Bacteremia occurred in 31.2% with no identified source in 2 patients. During the first month, 2 cases of endocarditis, 1 case of meningitis, and 4 deaths occurred. CONCLUSION:We confirm the importance of underlying diseases in the emergence of S. agalactiae infections.
journal_name
Med Mal Infectjournal_title
Medecine et maladies infectieusesauthors
Lefebvre N,Forestier E,Mohseni-Zadeh M,Remy V,Lesens O,Kuhnert C,Poindron V,Riegel P,Piémont Y,Christmann D,Hansmann Ydoi
10.1016/j.medmal.2007.04.003subject
Has Abstractpub_date
2007-12-01 00:00:00pages
796-801issue
12eissn
0399-077Xissn
1769-6690pii
S0399-077X(07)00190-4journal_volume
37pub_type
杂志文章abstract：INTRODUCTION:Nosocomial infections are a matter of concern in surgical wards. Their incidence is constantly increasing, especially among immunocompromised patients who are vulnerable to colonization by opportunistic pathogens such as Staphylococcus aureus. The bacterium accumulates resistance mechanisms against antibio...
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