当前位置： SCI文献检索 > MEDECINE ET MALADIES INFECTIEUSES期刊下所有文献 > Non-compliance with IDSA guidelines for patients presenting with methicillin-susceptible Staphylococcus aureus prosthetic joint infection is a risk factor for treatment failure.

Non-compliance with IDSA guidelines for patients presenting with methicillin-susceptible Staphylococcus aureus prosthetic joint infection is a risk factor for treatment failure.

Abstract：

OBJECTIVE:The long-term impact of treatment strategies proposed by the IDSA guidelines for patients presenting with methicillin-susceptible S. aureus (MSSA) prosthetic joint infection (PJI) is not well-known. PATIENTS AND METHODS:Retrospective (2000-2010) cohort study including patients presenting with MSSA hip or knee PJI. A univariate Cox analysis was performed to determine if the non-compliance with IDSA surgical guidelines was a risk factor for treatment failure. RESULTS:Eighty-nine patients with a mean follow-up of 2.8 years were included. Non-compliance with IDSA surgical guidelines was associated with treatment failure (hazard ratio 2.157; 95% CI [1.022-4.7]). The American Society of Anesthesiologists score, inadequate antimicrobial therapy, and a rifampicin-based regimen did not significantly influence patient outcome. CONCLUSION:Based on the IDSA guidelines, if a patient presenting with MSSA PJI is not eligible for implant retention, complete implant removal is needed to limit treatment failure.

journal_name

Med Mal Infect

journal_title

Medecine et maladies infectieuses

authors

Bouaziz A,Uçkay I,Lustig S,Boibieux A,Lew D,Hoffmeyer P,Neyret P,Chidiac C,Ferry T

doi

10.1016/j.medmal.2017.09.016

subject

Has Abstract

pub_date

2018-05-01 00:00:00

pages

207-211

issue

3

eissn

0399-077X

issn

1769-6690

pii

S0399-077X(16)30664-3

journal_volume

48

pub_type

杂志文章

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