Abstract:
:This study was designed to examine the effects of dose of recombinant human BMP-2 (rhBMP-2) on bone formation at palatal sites in 10-week-old (10w) and 70-week-old (70w) rats, when combined with a polylactate-polyglycolate copolymer/gelatine sponge (PGS). New bone formation was observed at six weeks after implantation. In the 10w rats, thickness of new bone (TNB) increased as the dosage increased from 0 microg to 4 microg, and decreased significantly as the dosage increased from 8 microg to 24 microg. In contrast, in the 70w rats, TNB increased as the dosage increased from 0 microg to 16 microg, and did not significantly change as the dosage increased from 16 microg to 24 microg. These results suggest that the most effective dosage of rhBMP-2 for induction of bone formation varies according to age.
journal_name
Dent Mater Jjournal_title
Dental materials journalauthors
Yamaji K,Kawanami M,Matsumoto A,Odajima T,Nishitani Y,Iwasaka K,Yoshimitsu K,Yoshiyama Mdoi
10.4012/dmj.26.481subject
Has Abstractpub_date
2007-07-01 00:00:00pages
481-6issue
4eissn
0287-4547issn
1881-1361journal_volume
26pub_type
杂志文章abstract::To improve the bioactivity of titanium surfaces, glow discharge was used to facilitate collagen grafting on titanium disks. Titanium test specimens were pre-treated by glow discharge fed with a mixture of argon and allylamine (AA) gases. Treated titanium disks were then grafted with type I collagen using glutaraldehyd...
journal_title:Dental materials journal
pub_type: 杂志文章
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更新日期:2008-05-01 00:00:00
abstract::Miniplates have been used during the last decade to facilitate stability between bony fragments in the maxillofacial region and are currently the preferred surgical method for the fixation of fractures and osteotomies. The aim of this study was to evaluate and compare the biomechanical behaviors of six different types...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2013-315
更新日期:2014-01-01 00:00:00
abstract::Though zirconia has been used in dental implant fixtures, the biocompatibility of the zirconia surface is not optimal for the surrounding tissue, and many surface modifications have been attempted. We have developed a novel method for improving the biocompatibility of zirconia by incorporating Ca ions. Elemental analy...
journal_title:Dental materials journal
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doi:10.4012/dmj.2014-199
更新日期:2015-01-01 00:00:00
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journal_title:Dental materials journal
pub_type: 杂志文章
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更新日期:2007-03-01 00:00:00
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journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.21.83
更新日期:2002-06-01 00:00:00
abstract::The purpose of this study was to investigate the effect of modifying aluminum oxide slips with magnesium oxide (MgO) to create a jointing material for In-Ceram Alumina. Jointed In-Ceram Alumina bars with In-Ceram Alumina slips containing 0-1.0 mass% MgO were examined by a three-point bending test. Joint-free bars were...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.27.251
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abstract::We evaluated the effect of different curing strategies for universal adhesives on micro-tensile bond strength (μTBS) between resin cement and dentin and/or between resin cement and indirect resin composite. Flat coronal dentin surfaces and composite resin disks were pretreated with silane-containing universal adhesive...
journal_title:Dental materials journal
pub_type: 杂志文章
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更新日期:2018-06-08 00:00:00
abstract::The human antimicrobial peptide beta-defensin-2 (hBD2) shows broad antibacterial activity and infrequent bacterial resistance. Here mesoporous bioactive glass (MBG) was loaded with hBD2, forming hBD2-loaded MBG (BD-MBG). The antibacterial and osteogenic effects of BD-MBG were investigated in comparison with MBG and th...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2020-105
更新日期:2020-12-24 00:00:00
abstract::This study determined the discoloration of five CAD/CAM resins, four manually polymerized resins, and glass-ceramic as control group. Specimens were divided into three groups (N=300, n=30) to be stored in coffee, black tea and red wine (n=10). The discoloration was measured using a spectrophotometer after 1, 7, 29, 90...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2011-238
更新日期:2012-01-01 00:00:00
abstract::This study aimed to introduce a procedure for determining the bilinear elastic moduli (E1 and E2) of the periodontal ligament for a mathematical tooth model to analyse stress in the mandible. The bone and tooth morphology were scanned from a dry skull and an extracted intact tooth, respectively, and reconstructed in a...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2010-170
更新日期:2011-01-01 00:00:00
abstract::This study evaluated the effect of resin coating (COA) on dentin bond strength (BS) of five resin cements (RC). Ten groups were tested, according to RC and COA combinations. RCs were applied onto prepolymerized resin discs, which were bonded to dentin surfaces. Teeth were stored in water for 24 h, subjected to 5,000 t...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2015-099
更新日期:2015-01-01 00:00:00
abstract::Application of a light-cured porcelain margin is a technique which has been developed recently. In this study, we compared the porcelain margin properties of the porcelain-light-cured resin matrix system and the traditional porcelain-water system, in terms of volumetric shrinkage, density, compressive strength, surfac...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.14.1
更新日期:1995-06-01 00:00:00
abstract::The effectiveness of a barbituric acid/copper (II) chloride initiator system in dentin was examined in terms of the effects of barbituric acid structures and dentin conditioners on bond strength. Curing times and tensile bond strengths to bovine dentin were measured for PMMA/MMA resins in conjunction with initiators c...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.14.221
更新日期:1995-12-01 00:00:00
abstract::To evaluate the cytotoxicity of resin cements on dental pulp-derived cells (bDPCs), Bifix QM (BQM), Choice 2(C2), RelyX U200(RU200), Maxcem Elite(ME), and Multilink Automix(MA) were tested. The materials were incubated in DMEM for 72 h. A real-time cell analyzer was used to evaluate cell survival. The statistical anal...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2014-167
更新日期:2015-01-01 00:00:00
abstract::The objective of this work was to determine the antimicrobial and antibiofilm properties of mineral trioxide aggregate (MTA) supplemented with bismuth lipophilic nanoparticles (BisBAL NPs). The antimicrobial activity of the composite MTA-BisBAL NPs was determined by the disk diffusion assay, while antibiofilm activity...
journal_title:Dental materials journal
pub_type: 杂志文章
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更新日期:2017-07-26 00:00:00
abstract::This study evaluated the effects of combining enamel microabrasion and dental bleaching on the physical properties of enamel, using in vitro and in situ conditions and evaluating surface roughness, enamel microhardness and scanning electron microscopy images. One hundred sound bovine teeth were sectioned and cut into ...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2014-334
更新日期:2016-01-01 00:00:00
abstract::The objective was to compare bond strengths of adhesives with/without thermocycling and to analyze the micromorphology of resindentin interfaces. Flat dentin surfaces were prepared and divided into eight groups to bond with four etch-and-rinse adhesives (Optibond FL, Adper Scotchbond Multi-Purpose, Optibond Solo Plus,...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2015-253
更新日期:2016-01-01 00:00:00
abstract::The three-dimensional dynamic movement of the abutment tooth was successfully analyzed on a simulation model utilizing the mandibular kinesiography. When the unilateral free-end denture retained by the RPA, RPI or Aker's clasp was subjected to various directions of loads, the abutment tooth was inclined mainly by the ...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.8.56
更新日期:1989-06-01 00:00:00
abstract::A new tensile fatigue test using a stainless steel screw was introduced. A transparent PMMA rod was selected as the test material. A hole was drilled and tapped into the rod; a screw was put into the rod with dental cement or without cementation. Three types of cyclic loads were applied to the test piece; the number o...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.11.141
更新日期:1992-12-01 00:00:00
abstract::This in vitro study aimed to investigate the effects of glass-ionomer and flowable composite liners on the fracture resistance of Class II amalgam and composite restorations. Group 1 cavities were restored with amalgam and Group 4 cavities with nanofill composite after the application of a dentin-bonding agent. For th...
journal_title:Dental materials journal
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doi:10.4012/dmj.2013-053
更新日期:2013-01-01 00:00:00
abstract::A new method of all-ceramic production using alumina coping has been developed. The present study investigates the influence of secondary firing (glass infiltration firing) conditions. Samples of porcelain build-up without secondary firing were also assessed. The suitability of coping that included secondary firing wa...
journal_title:Dental materials journal
pub_type: 杂志文章
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更新日期:2016-01-01 00:00:00
abstract::The aim of this in vitro study was to evaluate the effects of desensitizer pre-treatment on in-office bleaching using an artificial discoloration tooth model. The stained specimens were divided into four groups (n=10); without application (Control group), Shield Force plus (SF group), UltraEz (UE group) and Teeth Mate...
journal_title:Dental materials journal
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doi:10.4012/dmj.2018-129
更新日期:2019-10-02 00:00:00
abstract::The purpose of this study was to examine the antibacterial activity of composite resin with glass-ionomer filler particles versus that of contemporary commercial composite resins. Three composite resins were used: Beautifil II (containing S-PRG filler), Clearfil AP-X, and Filtek Z250. Resin blocks were bonded to maxil...
journal_title:Dental materials journal
pub_type: 杂志文章,随机对照试验
doi:10.4012/dmj.2009-050
更新日期:2010-03-01 00:00:00
abstract::This study evaluated and compared the influence of different supporting abutment models on the fracture loads of three-unit fixed dental prostheses (FDPs) fabricated from the following materials (n=24/material): (i) IPS e.max CAD-on, (ii) IPS e.max ZirCAD, and (iii) Telio CAD. Twelve FDPs of each group were adhesively...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2013-344
更新日期:2014-01-01 00:00:00
abstract::Three commercially available porcelains bonded to titanium were evaluated to determine the weakest zone of the titanium-porcelain bonding structures. Tensile bond tests were performed for these specimens (NO, DU, and VI) and for Ni-Cr alloy-porcelain bonding samples that served as controls. The maximum bond strengths ...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2013-263
更新日期:2014-01-01 00:00:00
abstract::The clinical feasibility of a novel device called a Cariotester was investigated by measuring the Knoop hardness (KHN) of white spot lesions diagnosed as ICDAS code 1, 2 or 3. To obtain an equation for converting the Cariotester indentation depth into the KHN, a regression analysis was performed between the depth and ...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2014-282
更新日期:2015-01-01 00:00:00
abstract::This study evaluated the influence of filling technique and curing mode on the microtensile bond strengths (MTBS) of composite cores to pulpal floor dentin. Access cavities of human molars with pulpal floor dentin were restored with a two-step self-etch adhesive system, Clearfil Liner Bond 2V and a composite core, Cle...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2009-104
更新日期:2010-10-01 00:00:00
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journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2013-319
更新日期:2014-01-01 00:00:00
abstract::This study aimed to evaluate the effect of an acidic-adjusted pH of solvent in silanization on the amount of fluoride released and mechanical properties of heat-cured acrylic resin containing a silanized fluoride-releasing filler. The experimental groups were divided into 4 groups; non-silanized, acidic-adjusted pH, n...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2015-403
更新日期:2016-01-01 00:00:00
abstract::The objective of this study was to evaluate, using methylene blue (MB), the effects of various light sources on the bleaching action of hydrogen peroxide (H(2)O(2)) with two titanium dioxide (TiO(2)) photocatalysts - an ultraviolet light-activated TiO(2) photocatalyst (UVTiO(2)) versus a visible light-activated TiO(2)...
journal_title:Dental materials journal
pub_type: 杂志文章
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更新日期:2009-11-01 00:00:00