Abstract:
:The human antimicrobial peptide beta-defensin-2 (hBD2) shows broad antibacterial activity and infrequent bacterial resistance. Here mesoporous bioactive glass (MBG) was loaded with hBD2, forming hBD2-loaded MBG (BD-MBG). The antibacterial and osteogenic effects of BD-MBG were investigated in comparison with MBG and the blank control (BC). The result showed that BD-MBG yielded sustained hBD2 release for more than 7 weeks in vitro, and resulted in significantly lower amounts of viable bacteria and colony forming units, and significantly higher levels of bacterial protein release compared with those in the BC and MBG groups (all p<0.05). Compared with that in the BC group, significantly higher bone marrow stromal cell (BMSC) proliferation rates, alkaline phosphatase (ALP) activity, calcium nodule formation, and expression levels of early and late osteogenic makers were observed after MBG and BD-MBG treatments (p<0.05). Thus, BD-MBG inhibited bacterial growth, damaged their membrane, and promoted early and late osteogenic BMSC differentiation.
journal_name
Dent Mater Jjournal_title
Dental materials journalauthors
Ren L,Zhang Z,Deng C,Zhang N,Li Ddoi
10.4012/dmj.2020-105subject
Has Abstractpub_date
2020-12-24 00:00:00eissn
0287-4547issn
1881-1361pub_type
杂志文章abstract::The physical properties of experimental visible light-activated resins containing dyestuff, which could be quickly discolored by irradiation was, evaluated by analyzing light absorbance characteristics and measuring micro Vickers hardness. The experimental resin, which was prepared by mixing equivalent weights of Bis ...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.8.147
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abstract::The purpose of this study was to evaluate the effect of different polymerization cycles on the flexural strengths and microhardness of two denture base materials (Meliodent and Paladent). Heat-polymerized acrylic resin specimens (65.0 mm long×10.0 mm wide×2.5 mm in height) were prepared using different short and long ...
journal_title:Dental materials journal
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journal_title:Dental materials journal
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abstract::The corrosion behavior of three Ni-Ti alloys with compositions as commercial super-elastic orthodontic wires was investigated using polished plate specimens. Corrosion resistance was estimated by potentiodynamic polarization measurement in 0.9% NaCl and 1% lactic acid solutions and analysis of released metals by atomi...
journal_title:Dental materials journal
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doi:10.4012/dmj.17.31
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abstract::The aim of this study was to investigate and compare the radio-opacity of core materials for all-ceramic restorations, such as zirconia (NANOZR and Y-TZP) and alumina, against commercially pure titanium (cpTi) and aluminum. X-ray images were taken under general settings using an X-ray film. The X-ray film images were ...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2009-54
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abstract::The objective of this study is to develop a casting investment that prevents the blackening of the cast surface of noble metal alloys. The experimental investments were prepared using a gypsum-bonded investment in which the metallic powders such as boron (B), silicon (Si), aluminum (Al) and titanium (Ti) were added as...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.22.87
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abstract::The effect of warm air-blowing on the sealing ability of two one-bottle and one two-bottle silane-containing universal adhesives (UAs) applied to lithium disilicate ceramics (LDS) was evaluated. Tapered cavities prefabricated in LDS blocks (IPS e.max CAD) were treated by the adhesives, air-blown either with normal air...
journal_title:Dental materials journal
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doi:10.4012/dmj.2020-057
更新日期:2020-10-24 00:00:00
abstract::This study evaluated the influence of heat treatment (HT) of the silane on the microtensile bond strength of resin cement to a feldspathic ceramic. Ceramic (VITA VM7) and composite blocks (N=32) were divided into four groups (n=6 for bond test, n=2 for SEM) at random and subject to following sequence of conditioning: ...
journal_title:Dental materials journal
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2011-01-01 00:00:00
abstract::This study evaluated the irrigation extrusion and smear layer (SL) removal of continuous ultrasonic irrigation (CUI). Forty root canals were shaped, embedded in warm sterile saline agar colored with 1% acid red, and distributed into four groups; three groups had the final irrigation sequence of sodium hypochlorite and...
journal_title:Dental materials journal
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journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2016-303
更新日期:2017-07-26 00:00:00
abstract::The use of a single metal for all restorations would be necessary because it protects against metal corrosion caused by the contact of different metals. For this "one-metal rehabilitation" concept, non-alloyed commercially pure (CP) titanium should be used for all restorations. Titanium frameworks have been cast and u...
journal_title:Dental materials journal
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doi:10.4012/dmj.2017-137
更新日期:2017-09-26 00:00:00
abstract::Effects of functionally gradient calcium phosphate consisting of hydroxyapatite (HAP) and alpha-tricalcium phosphate (alpha-TCP) on proliferation and differentiation of osteoblasts were evaluated using MC3T3-E1 cells. There were no significant differences in the proliferation of MC3T3-E1 cells among HAP-alpha-TCP func...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.24.207
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abstract::Temperature dependencies of thermal expansion coefficients for the alloys of Pd-Ag, Pd-Cu and Pd-Co binary systems were measured at temperatures up to 900 degrees C, with heating and cooling rates of 5 degrees C/min. The coefficient of thermal expansion of alloys with no transformation in the temperature range of inte...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.9.47
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abstract::The influence of the number of cycles on shear fatigue strength to enamel and dentin using dental adhesives in self-etch mode was investigated. A two-step self-etch adhesive and two universal adhesives were used to bond to enamel and dentin in self-etch mode. Initial shear bond strength and shear fatigue strength to e...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2017-012
更新日期:2018-01-30 00:00:00
abstract::This study investigated hydrogen peroxide (H2O2) concentration of two home bleaching gels, in their dispensing syringes and their degradation in vivo in intraoral bleaching trays. Two bleaching gels were studied, 7.5% hydrogen peroxide (HP) and 20% carbamide peroxide (CP). The concentration of H2O2 was determined in d...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2012-317
更新日期:2013-01-01 00:00:00
abstract::This in vitro study aimed to investigate the effects of glass-ionomer and flowable composite liners on the fracture resistance of Class II amalgam and composite restorations. Group 1 cavities were restored with amalgam and Group 4 cavities with nanofill composite after the application of a dentin-bonding agent. For th...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2013-053
更新日期:2013-01-01 00:00:00
abstract::The study evaluated changes in total enzymatic activity and degradation of demineralized dentin following the application of universal or self-etch adhesives. The universal adhesives -Scotchbond Universal (SU) and All-Bond Universal (ABU) and self-etch adhesives -Adper Easy Bond (EB) and G-aenial Bond (GB) were used f...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2019-304
更新日期:2020-12-03 00:00:00
abstract::This study evaluated the effects of ceramic surface treatment agents on shear bond strengths to ceramic materials with and without thermocycling. Ceramic plates were prepared from feldspathic ceramic; AAA, lithium disilicate ceramic material; IPS e.max Press, zirconia ceramic; Lava. Ceramic surfaces were pretreated wi...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2016-383
更新日期:2017-11-29 00:00:00
abstract::This paper reviews the development of dental adhesives by collating information of related studies from original scientific papers, reviews, and patent literatures. Through our development, novel radical polymerization initiators, adhesive monomers, and microcapsules were synthesized, and their effects on adhesion wer...
journal_title:Dental materials journal
pub_type: 杂志文章,评审
doi:10.4012/dmj.2009-057
更新日期:2010-03-01 00:00:00
abstract::The anti-suck-back ability of five new high-speed air turbine handpiece models was evaluated in this study. First, suck-back pressure with water displacement within a glass tube was measured. Next, under three different conditions, how many on-off times it takes before fluorescent stains became visible on a piece of g...
journal_title:Dental materials journal
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abstract::In this study, effects of the degree of dissociation of acids on the hydrolysis rate of methoxy group in γ-methacryloxypropyltrimethoxysilane (γ-MPS) and the adsorption characteristics of γ-MPS on ceramic surfaces were studied using acetic, phosphoric, and hydrochloric acids. Hydrolytic stability of γ-MPS adsorption l...
journal_title:Dental materials journal
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journal_title:Dental materials journal
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journal_title:Dental materials journal
pub_type: 临床试验,杂志文章,随机对照试验
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abstract::The depths of cure and the distributions of degree of conversion (DC), polymerization conversion (PC) and percent pendant double bonds (PDB) of light-cured composite resins cured under various intensities of light were investigated. When the total amount of exposure, represented by the product of the light intensity a...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.13.198
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abstract::Multi-purpose bonding performance of three kinds of newly synthesized phosphonic acid monomers was investigated. Methacryloxyalkyl or acryloxyalkyl phosphonoacetates of 6-MHPA, 6-AHPA, 10-MDPA were synthesized in 42.8-51.9% yields with a light yellow viscous liquid, and identified as new compounds by 1H NMR, IR, and e...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.26.105
更新日期:2007-01-01 00:00:00
abstract::The reinforcement mechanism of dentin mechanical properties by intracanal medicaments was investigated. The dumbbell-shaped specimens were prepared from a collagen sheet, demineralized dentin and organic dissolved dentin. After immersing the specimens in intracanal medicaments (eugenol and formocresol), the tensile te...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.18.304
更新日期:1999-09-01 00:00:00
abstract::Initial attachment of human oral keratinocytes (HOKs) cultured on mirror-surfaced commercially pure titanium (Ti) or yttria-stabilized tetragonal zirconia polycrystals (TZP) was investigated. Numbers of viable attached HOKs, their mRNAs and proteins expression of laminin γ2 and integrin β4 were evaluated using the WST...
journal_title:Dental materials journal
pub_type: 杂志文章
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journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2018-102
更新日期:2019-03-31 00:00:00
abstract::This study aimed to evaluate the effect of sulfinic acid sodium salt interposition after acid and sodium hypochlorite treatment (NC treatment) on dentin bonding durability using a mild type one-step self-etching adhesive. Fifteen human third molars were randomly assigned into three experimental groups according to den...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2017-105
更新日期:2017-11-29 00:00:00
abstract::This study investigated the efficacies of adhesive resin cements (Clearfil SA Luting, Maxcem, G-CEM, RelyX Unicem Clicker, Vitremer Paste) for bonding to Ag-Pd-Cu-Au alloy not surface-pretreated with metal primer. For control, Panavia F 2.0 -developed for use with a proprietary metal primer, Alloy Primer- was tested w...
journal_title:Dental materials journal
pub_type: 杂志文章
doi:10.4012/dmj.2010-093
更新日期:2011-01-01 00:00:00