Abstract:
BACKGROUND:Dysphagia diagnosis is limited by our inability to evaluate the underlying neuromuscular pathology of swallowing. A novel approach using pharyngeal surface electromyography (PsEMG) has been reported in the literature. OBJECTIVE:Three exploratory projects were undertaken to provide data toward the validation of PsEMG as a clinical measure of pharyngeal physiology. The first evaluates laterality of electrode placement in the pharynx. The second and third evaluate PsEMG using a circumferential and unidirectional electrode, respectively, during swallowing maneuvers. METHODS:In experiment 1, a catheter housing 3 manometric sensors and 1 bipolar PsEMG electrode was randomly inserted in each nares of 10 participants. Moving jaw radiographs were taken, and the PsEMG electrode was measured in millimeters from midline. In experiments 2 and 3, the catheter was placed in 22 and 40 research participants, respectively. Waveform characteristics were collected during swallowing maneuvers. The 2 experiments differed by type of electrode (circumferential, unidirectional) and swallowing maneuver (noneffortful and effortful swallow; noneffortful, effortful, and tongue-hold swallow). RESULTS:Midline electrode placement occurred on 20% of trials with deviation of up to 14.7 mm on all other trials. Maneuver-specific differences in amplitude were not detected with PsEMG; unacceptable levels of intrasubject and intersubject variability were identified. Temporal relationships of PsEMG and pharyngeal manometric pressure appeared appropriate. The unidirectional electrode revealed a unique bimodal PsEMG pattern that may reflect sequential contraction of muscles of the posterior pharyngeal wall. CONCLUSIONS:The current PsEMG design and procedures do not validly measure pharyngeal muscle activity. Recommendations for improved methods are provided.
journal_name
Neurorehabil Neural Repairjournal_title
Neurorehabilitation and neural repairauthors
Doeltgen SH,Hofmayer A,Gumbley F,Witte U,Moran C,Carroll G,Huckabee MLdoi
10.1177/1545968306293448subject
Has Abstractpub_date
2007-05-01 00:00:00pages
250-62issue
3eissn
1545-9683issn
1552-6844pii
1545968306293448journal_volume
21pub_type
杂志文章abstract::Neuroplasticity is critical for learning, memory, and recovery of lost function following neurological damage. Noninvasive brain stimulation (NIBS) techniques can induce neuroplastic changes in the human cortex that are behaviorally relevant, raising the exciting possibility that these techniques might be therapeutica...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968314562649
更新日期:2015-09-01 00:00:00
abstract::Background. Understanding the factors that influence language recovery in aphasia is important for improving prognosis and treatment. Chronic comprehension impairments in Wernicke's aphasia (WA) are associated with impairments in auditory and phonological processing, compounded by semantic and executive difficulties. ...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968319868709
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:The assessment of rehabilitation efficacy in spinal cord injury (SCI) should be based on a combination of neurological and functional outcome measures. The Spinal Cord Independence Measure II (SCIM II) is an independence scale that was specifically developed for subjects with SCI. However, little is known ab...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,多中心研究
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更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Individuals with unilateral vestibular hypofunction (UVH) alter their movement and reduce mobility to try to stabilize their gaze and avoid symptoms of dizziness and vertigo. OBJECTIVE:To determine if individuals with UVH 6 weeks after surgery demonstrate altered head and trunk kinematics during community a...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968318770271
更新日期:2018-04-01 00:00:00
abstract::Partnered tango dance can improve balance and gait in individuals with Parkinson's disease (PD). Partnered dance may allow these individuals to challenge balance more than nonpartnered dance. Alternatively, partnered practice could reduce balance gains because the participant may rely on the partner as a balance aid w...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,随机对照试验
doi:10.1177/1545968309353329
更新日期:2010-05-01 00:00:00
abstract::Implementation is the use of strategies to adopt and integrate evidence-based health interventions and to change practice patterns. In their article, "Implementation-the missing link in the research translation pipeline," Lynch et al1 report that only a small fraction of published stroke rehabilitation research in lea...
journal_title:Neurorehabilitation and neural repair
pub_type: 评论,杂志文章
doi:10.1177/1545968318794904
更新日期:2018-09-01 00:00:00
abstract:PURPOSE:Walking speed is a cardinal indicator of poststroke gait performance; however, no consensus exists regarding the optimal treatment method(s) for its enhancement. The most widely accepted criterion for establishing the contribution of treatment to walking speed is the gain in speed. The actual speed, however, at...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,评审
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更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:This study investigated the course and relationship between investigator-determined and patient-reported level of independence within the first year after spinal cord injury (SCI). The authors examined variables that contributed to these scores. METHODS:In this observational cohort study, 73 patients with tr...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
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更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Selection of patients who are most and least likely to benefit from constraint-induced therapy (CIT) for the upper extremity is uncertain. OBJECTIVE:This study investigated demographic and clinical characteristics that may predict outcomes for a distributed form of CIT. METHODS:A group of 57 patients were ...
journal_title:Neurorehabilitation and neural repair
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abstract:BACKGROUND:Somatosensory deficits are prevalent after stroke, but effective interventions are limited. Brain stimulation of the contralesional primary somatosensory cortex (S1) is a promising adjunct to peripherally administered rehabilitation therapies. OBJECTIVE:To assess short-term effects of repetitive transcrania...
journal_title:Neurorehabilitation and neural repair
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更新日期:2021-01-29 00:00:00
abstract::Background. Although dopaminergic medication improves dual task walking in people with Parkinson disease (PD), the underlying neural mechanisms are not yet fully understood. As prefrontal cognitive resources are involved in dual task walking, evaluation of the prefrontal cortex (PFC) is required. Objective. To investi...
journal_title:Neurorehabilitation and neural repair
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journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,随机对照试验
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更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:Step length asymmetry (SLA) is a common hallmark of gait poststroke. Though conventionally viewed as a spatial deficit, SLA can result from differences in where the feet are placed relative to the body (step position strategy), the timing between foot strikes (step time strategy), or the velocity of the body...
journal_title:Neurorehabilitation and neural repair
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abstract:BACKGROUND:Current knowledge regarding the time course of aphasia recovery is based on observations limited to the first years after stroke. OBJECTIVE:The authors studied long-term outcome (25 years) of language in a patient with global aphasia. METHODS:A 37-year-old man with global aphasia from a large ischemic lesi...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968310368962
更新日期:2010-11-01 00:00:00
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更新日期:2006-12-01 00:00:00
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journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,随机对照试验
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更新日期:2011-07-01 00:00:00
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journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,随机对照试验
doi:10.1177/1545968314541172
更新日期:2015-02-01 00:00:00
abstract::Stroke recovery research involves distinct biological and clinical targets compared to the study of acute stroke. Guidelines are proposed for the pre-clinical modeling of stroke recovery and for the alignment of pre-clinical studies to clinical trials in stroke recovery. ...
journal_title:Neurorehabilitation and neural repair
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更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Individuals with stroke often sustain bone loss on the hemiparetic side and are prone to fragility fractures. Exercise training may be a viable way to promote bone mineral density (BMD) and geometry in this population. OBJECTIVE:This was a pilot study to evaluate the effects of a 6-month treadmill exercise ...
journal_title:Neurorehabilitation and neural repair
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abstract:BACKGROUND:Autologous bone marrow mesenchymal cells that include stem cells (MSCs) are a clinically attractive cellular therapy option to try to treat severe spinal cord injury (SCI). OBJECTIVE:To study the possible value of MSCs injected intrathecally to enhance rehabilitation. METHODS:This case control, convenience...
journal_title:Neurorehabilitation and neural repair
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更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:Motor training alone or combined with transcranial direct current stimulation (tDCS) positioned over the motor cortex (M1) improves motor function in chronic stroke. Currently, understanding of how tDCS influences the process of motor skill learning after stroke is lacking. OBJECTIVE:To assess the effects o...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,随机对照试验
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更新日期:2018-04-01 00:00:00
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journal_title:Neurorehabilitation and neural repair
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journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968309348508
更新日期:2010-05-01 00:00:00
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journal_title:Neurorehabilitation and neural repair
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更新日期:2019-02-01 00:00:00
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更新日期:2009-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The question of the best therapeutic window in which noninvasive brain stimulation (NIBS) could potentiate the plastic changes for motor recovery after a stroke is still unresolved. Most of the previous NIBS studies included patients in the chronic phase of recovery and very few in the subacute...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
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更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Research has shown that movement impairments following stroke are typically associated with the limb contralateral to the side of the stroke. Prior studies identified ipsilateral motor declines across a variety of tasks. OBJECTIVE:Two experiments were conducted to better understand the ipsilateral contribut...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
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更新日期:2007-09-01 00:00:00