Abstract:
BACKGROUND:Several pilot studies have evoked interest in robot-assisted therapy (RAT) in children with cerebral palsy (CP). OBJECTIVE:To assess the effectiveness of RAT in children with CP through a single-blind randomized controlled trial. PATIENTS AND METHODS:Sixteen children with CP were randomized into 2 groups. Eight children performed 5 conventional therapy sessions per week over 8 weeks (control group). Eight children completed 3 conventional therapy sessions and 2 robot-assisted sessions per week over 8 weeks (robotic group). For both groups, each therapy session lasted 45 minutes. Throughout each RAT session, the patient attempted to reach several targets consecutively with the REAPlan. The REAPlan is a distal effector robot that allows for displacements of the upper limb in the horizontal plane. A blinded assessment was performed before and after the intervention with respect to the International Classification of Functioning framework: body structure and function (upper limb kinematics, Box and Block test, Quality of Upper Extremity Skills Test, strength, and spasticity), activities (Abilhand-Kids, Pediatric Evaluation of Disability Inventory), and participation (Life Habits). RESULTS:During each RAT session, patients performed 744 movements on average with the REAPlan. Among the variables assessed, the smoothness of movement (P < .01) and manual dexterity assessed by the Box and Block test (P = .04) improved significantly more in the robotic group than in the control group. CONCLUSIONS:This single-blind randomized controlled trial provides the first evidence that RAT is effective in children with CP. Future studies should investigate the long-term effects of this therapy.
journal_name
Neurorehabil Neural Repairjournal_title
Neurorehabilitation and neural repairauthors
Gilliaux M,Renders A,Dispa D,Holvoet D,Sapin J,Dehez B,Detrembleur C,Lejeune TM,Stoquart Gdoi
10.1177/1545968314541172subject
Has Abstractpub_date
2015-02-01 00:00:00pages
183-92issue
2eissn
1545-9683issn
1552-6844pii
1545968314541172journal_volume
29pub_type
杂志文章,随机对照试验abstract::Current assessments do not provide reliable factors predictive of outcome from stroke for stroke survivors of intermediate age and severity of deficit. We sought to investigate whether early rate of functional improvement can facilitate prediction of functional outcome, length of stay, and disposition beyond that affo...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/154596830001400309
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Neuromuscular electrical stimulation (NMES) of the muscles underlying the pharynx and faucial pillars affects the excitability of corticobulbar projections in a frequency- and duration-specific manner. The anterior hyomandibular (submental) muscles are primary targets for the clinical application of NMES to ...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968309360417
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:Peripheral axon regeneration is improved when the nerve lesion under consideration has recently been preceded by another nerve injury. This is known as the conditioning lesion effect (CLE). While the CLE is one of the most robust and well characterized means to enhance motor axon regeneration in experimental...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968318790020
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:and purpose. Mental practice (MP), which involves cognitive rehearsal of physical movements, is a noninvasive, inexpensive method of enabling repetitive, task-specific practice (RTP). Recent, randomized controlled data suggest that MP, when combined with an RTP therapy program, increases affected arm use and...
journal_title:Neurorehabilitation and neural repair
pub_type: 临床试验,杂志文章
doi:10.1177/1545968308326427
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The question of the best therapeutic window in which noninvasive brain stimulation (NIBS) could potentiate the plastic changes for motor recovery after a stroke is still unresolved. Most of the previous NIBS studies included patients in the chronic phase of recovery and very few in the subacute...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968314565465
更新日期:2015-09-01 00:00:00
abstract:PURPOSE:Impaired economy of gait, prevalent in chronic stroke secondary to residual gait deficits, is associated with intolerance for performing activities of daily living. Gait economy/efficiency is traditionally assessed by determining the rate of oxygen consumption during submaximal treadmill walking. However, the m...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968313497103
更新日期:2013-11-01 00:00:00
abstract::One in 2 Canadians is expected to acquire cancer in their lifetime. Many cancers, including breast, ovarian, and lung cancer, are treated using taxane chemotherapy with curative intent. A major adverse effect with the use of taxane chemotherapeutic agents is taxane-induced peripheral neuropathy (TIPN). Both positive (...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,评审
doi:10.1177/1545968319860486
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:Recent reports have indicated that bone marrow stromal cells (BMSCs) have the potential to improve neurological function when transplanted into models of central nervous system (CNS) disorders, including traumatic spinal cord injury. In this study, the authors aimed to clarify the underlying mechanism through...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968308315596
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:Interfacing an amputee's upper-extremity stump nerves to control a robotic hand requires training of the individual and algorithms to process interactions between cortical and peripheral signals. OBJECTIVE:To evaluate for the first time whether EEG-driven analysis of peripheral neural signals as an amputee ...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968311408919
更新日期:2012-03-01 00:00:00
abstract::The Motor Status Scale (MSS) measures shoulder, elbow (maximum score = 40), wrist, hand, and finger movements (maximum score = 42), and expands the measurement of upper extremity impairment and disability provided by the Fugl-Meyer (FM) score. This work examines the interrater reliability and criterion validity of the...
journal_title:Neurorehabilitation and neural repair
pub_type: 临床试验,杂志文章
doi:10.1177/154596830201600306
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:Wrist-worn accelerometry provides objective monitoring of upper-extremity functional use, such as reaching tasks, but also detects nonfunctional movements, leading to ambiguity in monitoring results. OBJECTIVE:Compare machine learning algorithms with standard methods (counts ratio) to improve accuracy in de...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968320962483
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Environmental enrichment (EE) is a complex living milieu that has been shown to enhance functional recovery versus standard (STD) housing after experimental traumatic brain injury (TBI) and therefore may be considered a rodent correlate of rehabilitation. However, the typical EE paradigm consists of continuo...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968310390520
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:Walking speed is a cardinal indicator of poststroke gait performance; however, no consensus exists regarding the optimal treatment method(s) for its enhancement. The most widely accepted criterion for establishing the contribution of treatment to walking speed is the gain in speed. The actual speed, however, at...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,评审
doi:10.1177/1545968308315997
更新日期:2008-11-01 00:00:00
abstract:PURPOSE:Sarcopenia and increased fat infiltration in muscle may play a role in the functional impairment and high risk for diabetes in stroke. Our purpose was to compare muscle volume and muscle attenuation across 6 muscles of the paretic and nonparetic thigh and examine the relationships between intramuscular fat and ...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968311408920
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Although functional imaging and neurophysiological approaches reveal alterations in motor and premotor areas after stroke, insights into neurobiological events underlying these alterations are limited in human studies. OBJECTIVE:We tested whether cerebral metabolites related to neuronal and glial compartmen...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968312469835
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Objective measures of functional walking remain scarce for individuals with incomplete spinal cord injury (ISCI). Hence, the authors developed the Spinal Cord Injury Functional Ambulation Profile (SCI-FAP), which encompasses the timed performance of 7 tasks, such as walking and negotiating obstacles, doors, ...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968310381250
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Many physical interventions can improve locomotor function in individuals with motor incomplete spinal cord injury (iSCI), although the training parameters that maximize recovery are not clear. Previous studies in individuals with other neurologic injuries suggest the intensity of locomotor training (LT) may...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,随机对照试验
doi:10.1177/1545968317731538
更新日期:2017-10-01 00:00:00
abstract:STATEMENT OF PROBLEM:To develop and evaluate a self-administered health-related quality of life (HRQOL) measure for peripheral neuropathy. METHODS:A field test measure of 162 items was developed that included the RAND-36 Health Survey as a generic core and a neuropathy-targeted supplement whose content was driven by r...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/154596830001400202
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Somatosensory deficits are prevalent after stroke, but effective interventions are limited. Brain stimulation of the contralesional primary somatosensory cortex (S1) is a promising adjunct to peripherally administered rehabilitation therapies. OBJECTIVE:To assess short-term effects of repetitive transcrania...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968321989338
更新日期:2021-01-29 00:00:00
abstract:BACKGROUND:The slow rate of nerve regeneration following injury can cause extended muscle denervation, leading to irreversible muscle atrophy, fibrosis, and destruction of motor endplates. The immunosuppressant FK506 (tacrolimus) has been shown to accelerate the rate of nerve regeneration and functional recovery. Howev...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,随机对照试验
doi:10.1177/1545968311431965
更新日期:2012-07-01 00:00:00
abstract::Proprioception is a vital aspect of motor control and when degraded or lost can have a profound impact on function in diverse clinical populations. This systematic review aimed to identify clinically related tools to measure proprioceptive acuity, to classify the construct(s) underpinning the tools, and to report on t...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,评审
doi:10.1177/1545968315573055
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Robot-assisted therapy (RT) is a current promising intervention in stroke rehabilitation, but more research is warranted for examining its efficacy and the dose-benefit relation. The authors investigated the effects of higher intensity versus lower intensity RT on movements of forearm pronatio...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,随机对照试验
doi:10.1177/1545968310394871
更新日期:2011-07-01 00:00:00
abstract::The Wolf Motor Function Test (WMFT) has been used in rehabilitation studies of chronic stroke patients, but until now its psychometric properties have not been evaluated in patients with subacute stroke. Two hundred twenty-nine participants with subacute stroke (3-9 months postinjury) at 7 research sites met inclusion...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968305276663
更新日期:2005-09-01 00:00:00
abstract::Background. Although dopaminergic medication improves dual task walking in people with Parkinson disease (PD), the underlying neural mechanisms are not yet fully understood. As prefrontal cognitive resources are involved in dual task walking, evaluation of the prefrontal cortex (PFC) is required. Objective. To investi...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968320924430
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Some noninvasive brain-computer interface (BCI) systems are currently available for locked-in syndrome (LIS) but none have incorporated a statistical language model during text generation. OBJECTIVE:To begin to address the communication needs of individuals with LIS using a noninvasive BCI that involves rap...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968313516867
更新日期:2014-05-01 00:00:00
abstract::This article summarizes the proceedings of an NIH workshop on timing, intensity, and duration of rehabilitation for acute stroke and hip fracture. Participants concentrated on methodological issues facing investigators and suggested priorities for future research in this area. ...
journal_title:Neurorehabilitation and neural repair
pub_type: 共识发展会议,杂志文章,评审
doi:10.1177/0888439003262041
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:A variety of rehabilitation strategies have been tried in patients with chronic hemianopia and quadrantanopia. The authors compared 2 approaches of blind field exploration in those with recent onset of disease. METHODS:A total of 20 patients with visual field defects were studied between 3 and 24 weeks prima...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,随机对照试验
doi:10.1177/1545968310372774
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:. Mental practice through motor imagery improves subsequent motor performance and thus mental training is considered to be a potential tool in neuromotor rehabilitation. OBJECTIVE:. The authors investigated whether a circadian fluctuation of the motor imagery process occurs, which could be relevant in sched...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968308321775
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:Motor training alone or combined with transcranial direct current stimulation (tDCS) positioned over the motor cortex (M1) improves motor function in chronic stroke. Currently, understanding of how tDCS influences the process of motor skill learning after stroke is lacking. OBJECTIVE:To assess the effects o...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,随机对照试验
doi:10.1177/1545968318769164
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Selection of patients who are most and least likely to benefit from constraint-induced therapy (CIT) for the upper extremity is uncertain. OBJECTIVE:This study investigated demographic and clinical characteristics that may predict outcomes for a distributed form of CIT. METHODS:A group of 57 patients were ...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968308321773
更新日期:2009-05-01 00:00:00