Abstract:
BACKGROUND:Research has shown that movement impairments following stroke are typically associated with the limb contralateral to the side of the stroke. Prior studies identified ipsilateral motor declines across a variety of tasks. OBJECTIVE:Two experiments were conducted to better understand the ipsilateral contributions to organization and execution of proximal upper extremity multisegment aiming movements in persons with right-hemispheric stroke. METHODS:Participants performed reciprocal aiming (Experiment 1) and 2-segment aiming movements (Experiment 2) on a digitizing tablet. In both experiments, target size and/or target orientation were manipulated to examine the influence of accuracy constraints on the planning and organization of movements. RESULTS:Kinematic measures, submovement analysis, and harmonicity measures were included in this study. Declines in organization and execution of multisegment movements were found to contribute to performance decrements and slowing in stroke patients. Furthermore, stroke patients were unable to efficiently plan multisegment movements as one functional unit, resulting in discrete movements. CONCLUSIONS:Results suggest the importance of considering ipsilateral contributions to the control and organization of targeted aiming movements as well as implications for rehabilitation and recovery.
journal_name
Neurorehabil Neural Repairjournal_title
Neurorehabilitation and neural repairauthors
Ketcham CJ,Rodriguez TM,Zihlman KAdoi
10.1177/1545968306297872subject
Has Abstractpub_date
2007-09-01 00:00:00pages
388-97issue
5eissn
1545-9683issn
1552-6844pii
1545968306297872journal_volume
21pub_type
杂志文章abstract:OBJECTIVE:To examine whether cerebral activity during passive movements decreases with time after stroke, and if reduced activity in the representation for the upper extremity can be reversed with training. METHODS:Brain activity was measured by functional magnetic resonance imaging (fMRI) during passive wrist flexion...
journal_title:Neurorehabilitation and neural repair
pub_type: 临床试验,杂志文章
doi:10.1177/1545968306296965
更新日期:2007-07-01 00:00:00
abstract:PURPOSE:Walking speed is a cardinal indicator of poststroke gait performance; however, no consensus exists regarding the optimal treatment method(s) for its enhancement. The most widely accepted criterion for establishing the contribution of treatment to walking speed is the gain in speed. The actual speed, however, at...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,评审
doi:10.1177/1545968308315997
更新日期:2008-11-01 00:00:00
abstract::The remarkable scientific and technological advances in the field of cell research have not been translated into viable restorative therapies for brain disorders. In this article, we examine the best available evidence for the clinical efficacy of reconstructive intracerebral transplantation in people with Parkinson's...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968316635277
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:High-intensity, variable stepping training can improve walking speed in individuals poststroke, although neuromuscular strategies used to achieve faster speeds are unclear. We evaluated changes in joint kinetics and neuromuscular coordination following such training; movement strategies consistent with intac...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968318817825
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Contradictory results have been reported for transcranial direct current stimulation (tDCS) as treatment for tinnitus. The recently developed high-definition tDCS (HD tDCS) uses smaller electrodes to limit the excitation to the desired brain areas. OBJECTIVE:The current study consisted of a retrospective pa...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968318787916
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Peripheral axon regeneration is improved when the nerve lesion under consideration has recently been preceded by another nerve injury. This is known as the conditioning lesion effect (CLE). While the CLE is one of the most robust and well characterized means to enhance motor axon regeneration in experimental...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968318790020
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Studies have demonstrated the efficacy of functional electrical stimulation in the management of foot drop after stroke. OBJECTIVE:To compare changes in walking performance with the WalkAide (WA) foot-drop stimulator and a conventional ankle-foot orthosis (AFO). METHODS:Individuals with stroke within the p...
journal_title:Neurorehabilitation and neural repair
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1177/1545968313481278
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Recovery of the sit-to-stand (StS) movement early after stroke could be improved by targeting physical therapy at the underlying movement deficits in those people likely to respond. AIM:To compare the movement characteristics of successful and failed StS movements in people early after stroke and identify w...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/1545968319846119
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:. Mental practice through motor imagery improves subsequent motor performance and thus mental training is considered to be a potential tool in neuromotor rehabilitation. OBJECTIVE:. The authors investigated whether a circadian fluctuation of the motor imagery process occurs, which could be relevant in sched...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968308321775
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:Low-frequency repetitive transcranial magnetic stimulation (rTMS) over the unaffected motor cortex may improve motor function of the paretic hand after stroke. However, low-frequency rTMS might adversely affect bimanual movement by decreasing transcallosal function. OBJECTIVE:The authors investigated whethe...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,随机对照试验
doi:10.1177/1545968311433295
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Retraining walking following spinal cord injury using visually guided tasks may be especially efficacious because it engages the motor cortex, whose input may facilitate improvements in functional walking. OBJECTIVES:To contrast 2 methods of retraining, one emphasizing precise, visually guided walking over ...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,随机对照试验
doi:10.1177/1545968313508473
更新日期:2014-05-01 00:00:00
abstract::Objectives. Memory training in combination with practice in semantic structuring and word fluency has been shown to improve memory performance. This study investigated the efficacy of a working memory training combined with exercises in semantic structuring and word fluency and examined whether training effects genera...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,随机对照试验
doi:10.1177/1545968314527352
更新日期:2015-01-01 00:00:00
abstract::The Motor Status Scale (MSS) measures shoulder, elbow (maximum score = 40), wrist, hand, and finger movements (maximum score = 42), and expands the measurement of upper extremity impairment and disability provided by the Fugl-Meyer (FM) score. This work examines the interrater reliability and criterion validity of the...
journal_title:Neurorehabilitation and neural repair
pub_type: 临床试验,杂志文章
doi:10.1177/154596830201600306
更新日期:2002-09-01 00:00:00
abstract::One in 2 Canadians is expected to acquire cancer in their lifetime. Many cancers, including breast, ovarian, and lung cancer, are treated using taxane chemotherapy with curative intent. A major adverse effect with the use of taxane chemotherapeutic agents is taxane-induced peripheral neuropathy (TIPN). Both positive (...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,评审
doi:10.1177/1545968319860486
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Autologous bone marrow mesenchymal cells that include stem cells (MSCs) are a clinically attractive cellular therapy option to try to treat severe spinal cord injury (SCI). OBJECTIVE:To study the possible value of MSCs injected intrathecally to enhance rehabilitation. METHODS:This case control, convenience...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968310369801
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:Conventional methods of rehabilitation in patients with chronic, severe motor impairments after stroke usually do not lessen paresis. OBJECTIVE:A novel therapeutic approach (assisted movement with enhanced sensation [AMES]) was employed in a medical device phase I clinical trial to reduce paresis and spasti...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968308317437
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:The slow rate of nerve regeneration following injury can cause extended muscle denervation, leading to irreversible muscle atrophy, fibrosis, and destruction of motor endplates. The immunosuppressant FK506 (tacrolimus) has been shown to accelerate the rate of nerve regeneration and functional recovery. Howev...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,随机对照试验
doi:10.1177/1545968311431965
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:Gait impairments after stroke arise from dysfunction of one or several features of the walking pattern. Traditional rehabilitation practice focuses on improving one component at a time, which may leave certain features unaddressed or prolong rehabilitation time. Recent work shows that neurologically intact a...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968318792623
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Upper limb function plays a significant role in enhancing independence for individuals with tetraplegia. However, there is limited knowledge about the specific input of sensorimotor deficits on upper limb function. Thus the theoretical framework designed to develop the Graded Redefined Assessment of Strength...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968313490998
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The question of the best therapeutic window in which noninvasive brain stimulation (NIBS) could potentiate the plastic changes for motor recovery after a stroke is still unresolved. Most of the previous NIBS studies included patients in the chronic phase of recovery and very few in the subacute...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968314565465
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Ambulating on stairs is an important aspect of daily activities for many individuals with incomplete spinal cord injury (SCI), and little is known about the effect of training for this specific task. OBJECTIVE:The goal of this study was to determine whether staircase ascent training enhances motor recovery ...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968310378510
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Surface electrical stimulation of the abdominal muscles, with electrodes placed in the posterolateral position, combined with a voluntary cough can assist clearance of airway secretions in individuals with high-level spinal cord injury (SCI). OBJECTIVE:To determine whether an increase in stimulus intensity ...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968314552527
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Suppression of activity in the contralesional motor cortex may promote recovery of function after stroke. Furthermore, the known depressant effects of low-frequency repetitive transcranial magnetic stimulation (rTMS) can be increased and prolonged by preceding it with 6-Hz priming stimulation. OBJECTIVE:The...
journal_title:Neurorehabilitation and neural repair
pub_type: 临床试验,杂志文章
doi:10.1177/1545968307305458
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The course of central and peripheral motor recovery after cervical spinal cord injury (SCI) may be investigated by electrophysiological measures. The goal of this study was to compare the 2 over the first year after injury in relation to motor gains. METHODS:Compound motor action potentials (C...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,多中心研究
doi:10.1177/1545968316688796
更新日期:2017-05-01 00:00:00
abstract:PURPOSE:Sarcopenia and increased fat infiltration in muscle may play a role in the functional impairment and high risk for diabetes in stroke. Our purpose was to compare muscle volume and muscle attenuation across 6 muscles of the paretic and nonparetic thigh and examine the relationships between intramuscular fat and ...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968311408920
更新日期:2011-11-01 00:00:00
abstract:STATEMENT OF PROBLEM:To develop and evaluate a self-administered health-related quality of life (HRQOL) measure for peripheral neuropathy. METHODS:A field test measure of 162 items was developed that included the RAND-36 Health Survey as a generic core and a neuropathy-targeted supplement whose content was driven by r...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/154596830001400202
更新日期:2000-01-01 00:00:00
abstract::Background. High-intensity repetitive training is challenging to provide poststroke. Robotic approaches can facilitate such training by unweighting the limb and/or by improving trajectory control, but the extent to which these types of assistance are necessary is not known. Objective. The purpose of this study was to ...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968319887685
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:There are indications that perilesional and remote peripheral motor axons may degenerate after spinal cord injury (SCI). The authors investigated the magnitude and dependence on severity of SCI of this degeneration as well as whether motor axons so affected can recover. METHODS:The function of the peripheral...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,多中心研究
doi:10.1177/1545968310368534
更新日期:2010-09-01 00:00:00
abstract::The first Stroke Recovery and Rehabilitation Roundtable established a game changing set of new standards for stroke recovery research. Common language and definitions were required to develop an agreed framework spanning the four working groups: translation of basic science, biomarkers of stroke recovery, measurement ...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章
doi:10.1177/1545968317732668
更新日期:2017-09-01 00:00:00
abstract::Background. Reorganization in motor areas have been suggested after motor imagery training (MIT). However, motor imagery involves a large-scale brain network, in which many regions, andnot only the motor areas, potentially constitute the neural substrate for MIT. Objective. This study aimed to identify the targets for...
journal_title:Neurorehabilitation and neural repair
pub_type: 杂志文章,随机对照试验
doi:10.1177/1545968319899919
更新日期:2020-04-01 00:00:00