Severe degeneration of peripheral motor axons after spinal cord injury: a European multicenter study in 345 patients.

abstract：OBJECTIVE:To investigate the individual occurrence of walking-related motor fatigue in persons with multiple sclerosis (PwMS), according to disability level and disease phenotype.Study design This was a cross-sectional, multinational study.Participants They were 208 PwMS from 11 centers with Expanded Disability Status ...

journal_title：Neurorehabilitation and neural repair

authors： Leone C,Severijns D,Doležalová V,Baert I,Dalgas U,Romberg A,Bethoux F,Gebara B,Santoyo Medina C,Maamâgi H,Rasova K,Maertens de Noordhout B,Knuts K,Skjerbaek A,Jensen E,Wagner JM,Feys P

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Selection of patients who are most and least likely to benefit from constraint-induced therapy (CIT) for the upper extremity is uncertain. OBJECTIVE:This study investigated demographic and clinical characteristics that may predict outcomes for a distributed form of CIT. METHODS:A group of 57 patients were ...

journal_title：Neurorehabilitation and neural repair

authors： Lin KC,Huang YH,Hsieh YW,Wu CY

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Functional connectivity is defined as the temporal correlation between spatially remote neurophysiological events. This method has become particularly useful for studying neuroplasticity to detect changes in the collaboration of brain areas during cortical reorganization. METHODS:In this article, the author...

journal_title：Neurorehabilitation and neural repair

authors： Klingner CM,Volk GF,Brodoehl S,Burmeister HP,Witte OW,Guntinas-Lichius O

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Resting brain activity can be modulated by motor tasks to adapt to function. In multiple sclerosis (MS) patients, altered resting-state functional connectivity (RS-FC) has been reported and associated with impaired function and disability; little is known on how RS-FC is modulated by a simple repetitive moto...

journal_title：Neurorehabilitation and neural repair

authors： Petsas N,Tomassini V,Filippini N,Sbardella E,Tona F,Piattella MC,Pozzilli C,Wise RG,Pantano P

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Interfacing an amputee's upper-extremity stump nerves to control a robotic hand requires training of the individual and algorithms to process interactions between cortical and peripheral signals. OBJECTIVE:To evaluate for the first time whether EEG-driven analysis of peripheral neural signals as an amputee ...

journal_title：Neurorehabilitation and neural repair

authors： Tombini M,Rigosa J,Zappasodi F,Porcaro C,Citi L,Carpaneto J,Rossini PM,Micera S

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Upper limb function plays a significant role in enhancing independence for individuals with tetraplegia. However, there is limited knowledge about the specific input of sensorimotor deficits on upper limb function. Thus the theoretical framework designed to develop the Graded Redefined Assessment of Strength...

journal_title：Neurorehabilitation and neural repair

authors： Kalsi-Ryan S,Beaton D,Curt A,Duff S,Jiang D,Popovic MR,Rudhe C,Fehlings MG,Verrier MC

更新日期：2014-01-01 00:00:00

abstract：:The Motor Status Scale (MSS) measures shoulder, elbow (maximum score = 40), wrist, hand, and finger movements (maximum score = 42), and expands the measurement of upper extremity impairment and disability provided by the Fugl-Meyer (FM) score. This work examines the interrater reliability and criterion validity of the...

journal_title：Neurorehabilitation and neural repair

authors： Ferraro M,Demaio JH,Krol J,Trudell C,Rannekleiv K,Edelstein L,Christos P,Aisen M,England J,Fasoli S,Krebs HI,Hogan N,Volpe BT

更新日期：2002-09-01 00:00:00

abstract：:Background. Severe poststroke arm impairment is associated with greater activation of the nonlesioned hemisphere during movement of the affected arm. The circumstances under which this activation may be adaptive or maladaptive remain unclear. Objective. To identify the functional relevance of key lesioned and nonlesio...

journal_title：Neurorehabilitation and neural repair

authors： Harrington RM,Chan E,Rounds AK,Wutzke CJ,Dromerick AW,Turkeltaub PE,Harris-Love ML

更新日期：2020-01-01 00:00:00

abstract：:Current assessments do not provide reliable factors predictive of outcome from stroke for stroke survivors of intermediate age and severity of deficit. We sought to investigate whether early rate of functional improvement can facilitate prediction of functional outcome, length of stay, and disposition beyond that affo...

journal_title：Neurorehabilitation and neural repair

authors： Ween JE,Mernoff ST,Alexander MP

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Recent studies have proposed a role for robotic gait training in participants with acquired brain injury, but the effects on the excitability of cortical and spinal neurons even in healthy participants are uncertain. OBJECTIVE:To investigate changes in corticospinal excitability in healthy participants afte...

journal_title：Neurorehabilitation and neural repair

authors： Blicher JU,Nielsen JF

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Ambulating on stairs is an important aspect of daily activities for many individuals with incomplete spinal cord injury (SCI), and little is known about the effect of training for this specific task. OBJECTIVE:The goal of this study was to determine whether staircase ascent training enhances motor recovery ...

journal_title：Neurorehabilitation and neural repair

authors： Singh A,Murray M,Houle JD

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:A recent review showed that no existing instrument measured the entire spectrum of health-related quality of life (HRQOL) in stroke patients. However, the HRQOL in stroke patients (HRQOLISP) questionnaire is valid and exceptionally comprehensive. Founded on a holistic model of human life, it comprises both p...

journal_title：Neurorehabilitation and neural repair

authors： Ojo Owolabi M

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The Unified Parkinson's Disease Rating Scale (UPDRS) is the "gold standard" assessment tool for characterizing impairments in persons with Parkinson's disease (PD); however, this scale's ability to predict functional capabilities across different functional tasks has not been adequately assessed in persons w...

journal_title：Neurorehabilitation and neural repair

authors： Song J,Fisher BE,Petzinger G,Wu A,Gordon J,Salem GJ

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Many physical interventions can improve locomotor function in individuals with motor incomplete spinal cord injury (iSCI), although the training parameters that maximize recovery are not clear. Previous studies in individuals with other neurologic injuries suggest the intensity of locomotor training (LT) may...

journal_title：Neurorehabilitation and neural repair

authors： Brazg G,Fahey M,Holleran CL,Connolly M,Woodward J,Hennessy PW,Schmit BD,Hornby TG

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Peripheral axon regeneration is improved when the nerve lesion under consideration has recently been preceded by another nerve injury. This is known as the conditioning lesion effect (CLE). While the CLE is one of the most robust and well characterized means to enhance motor axon regeneration in experimental...

journal_title：Neurorehabilitation and neural repair

authors： Franz CK,Puritz A,Jordan LA,Chow J,Ortega JA,Kiskinis E,Heckman CJ

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Confidence about balance may be an important factor affecting self-efficacy for daily activities after stroke. OBJECTIVE:The authors investigated whether confidence changes and the parameters that may predict changes in self-perceived balance within the first year of community reintegration. METHODS:In thi...

journal_title：Neurorehabilitation and neural repair

authors： Yiu J,Miller WC,Eng JJ,Liu Y

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:There is a need to identify reliable biomarkers of spinal cord injury recovery for clinical practice and clinical trials. OBJECTIVE:Our objective was to correlate serum albumin levels with spinal cord injury neurological outcomes. METHODS:We performed a secondary analysis of patients with traumatic spinal ...

journal_title：Neurorehabilitation and neural repair

authors： Tong B,Jutzeler CR,Cragg JJ,Grassner L,Schwab JM,Casha S,Geisler F,Kramer JLK

更新日期：2018-01-01 00:00:00

abstract：:The first Stroke Recovery and Rehabilitation Roundtable established a game changing set of new standards for stroke recovery research. Common language and definitions were required to develop an agreed framework spanning the four working groups: translation of basic science, biomarkers of stroke recovery, measurement ...

journal_title：Neurorehabilitation and neural repair

authors： Bernhardt J,Hayward KS,Kwakkel G,Ward NS,Wolf SL,Borschmann K,Krakauer JW,Boyd LA,Carmichael ST,Corbett D,Cramer SC

更新日期：2017-09-01 00:00:00

abstract：:Neuroplasticity is critical for learning, memory, and recovery of lost function following neurological damage. Noninvasive brain stimulation (NIBS) techniques can induce neuroplastic changes in the human cortex that are behaviorally relevant, raising the exciting possibility that these techniques might be therapeutica...

journal_title：Neurorehabilitation and neural repair

authors： Goldsworthy MR,Pitcher JB,Ridding MC

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Recovery from stroke is often said to have "plateaued" after 6 to 12 months. Yet training can still improve performance even in the chronic phase. Here we investigate the biomechanics of accuracy improvements during a reaching task and test whether they are affected by the speed at which movements are practi...

journal_title：Neurorehabilitation and neural repair

authors： Hammerbeck U,Yousif N,Hoad D,Greenwood R,Diedrichsen J,Rothwell JC

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Individuals with unilateral vestibular hypofunction (UVH) alter their movement and reduce mobility to try to stabilize their gaze and avoid symptoms of dizziness and vertigo. OBJECTIVE:To determine if individuals with UVH 6 weeks after surgery demonstrate altered head and trunk kinematics during community a...

journal_title：Neurorehabilitation and neural repair

authors： Paul SS,Dibble LE,Walther RG,Shelton C,Gurgel RK,Lester ME

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:In hemiplegic gait, step length typically differs in magnitude between paretic and nonparetic sides. However, the direction of step-length asymmetry varies across stroke patients. OBJECTIVE:The study sought to understand directional variations in step-length asymmetry in terms of asymmetries in forward foot...

journal_title：Neurorehabilitation and neural repair

authors： Roerdink M,Beek PJ

更新日期：2011-03-01 00:00:00

abstract：:Despite negative association in cognition and memory, mice harboring Val66Met BDNF SNP (BDNFM/M) exhibit enhanced motor recovery accompanied by elevated excitatory synaptic markers VGLUT1 and VGLUT2 in striatum contralateral to unilateral ischemic stroke. The cortico-striatal pathway is a critical gateway for plastici...

journal_title：Neurorehabilitation and neural repair

authors： Qin L,Actor-Engel HS,Woo MS,Shakil F,Chen YW,Cho S,Aoki C

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Cortical networks underlying motor imagery are functionally close to motor performance networks and can be activated by patients with severe motor disabilities. OBJECTIVE:The aim of the study was to examine the longitudinal effect of progressive motoneuron degeneration on cortical representation of motor im...

journal_title：Neurorehabilitation and neural repair

authors： Lulé D,Diekmann V,Kassubek J,Kurt A,Birbaumer N,Ludolph AC,Kraft E

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Perception of sound in the absence of an external auditory source is called tinnitus, which may negatively affect quality of life. Anodal transcranial direct current stimulation (tDCS) of the left temporoparietal area (LTA) was explored for tinnitus relief. OBJECTIVE:This pilot study examined tDCS dose (cur...

journal_title：Neurorehabilitation and neural repair

authors： Shekhawat GS,Stinear CM,Searchfield GD

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Current available therapies for Parkinson disease (PD) have strong limitations, and patients usually present with refractory symptoms despite all efforts. Deep brain stimulation (DBS), which has been used in PD patients for decades (since 1987), has best indications for symptoms like tremor, motor fluctuatio...

journal_title：Neurorehabilitation and neural repair

authors： Garcia BB,Junior ER,Araújo MFP,Simplício H

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:High-intensity, variable stepping training can improve walking speed in individuals poststroke, although neuromuscular strategies used to achieve faster speeds are unclear. We evaluated changes in joint kinetics and neuromuscular coordination following such training; movement strategies consistent with intac...

journal_title：Neurorehabilitation and neural repair

authors： Ardestani MM,Kinnaird CR,Henderson CE,Hornby TG

更新日期：2019-01-01 00:00:00

abstract：:Background. Stroke is one of the most common causes of physical disability worldwide. The majority of survivors experience impairment of movement, often with lasting deficits affecting hand dexterity. To date, conventional rehabilitation primarily focuses on training compensatory maneuvers emphasizing goal completion ...

journal_title：Neurorehabilitation and neural repair

authors： Mawase F,Cherry-Allen K,Xu J,Anaya M,Uehara S,Celnik P

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Contradictory results have been reported for transcranial direct current stimulation (tDCS) as treatment for tinnitus. The recently developed high-definition tDCS (HD tDCS) uses smaller electrodes to limit the excitation to the desired brain areas. OBJECTIVE:The current study consisted of a retrospective pa...

journal_title：Neurorehabilitation and neural repair

authors： Jacquemin L,Shekhawat GS,Van de Heyning P,Mertens G,Fransen E,Van Rompaey V,Topsakal V,Moyaert J,Beyers J,Gilles A

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Alterations in the function of spinal neuronal circuits underlying locomotion after a spinal cord injury (SCI) are associated with changes in the behavior of spinal reflexes (SRs) in both rats and humans. In healthy subjects, the SR consists of a dominant early reflex component, whereas in chronic, severely ...

journal_title：Neurorehabilitation and neural repair

authors： Hubli M,Dietz V,Bolliger M

更新日期：2012-02-01 00:00:00