The relationships between the unified Parkinson's disease rating scale and lower extremity functional performance in persons with early-stage Parkinson's disease.

Abstract:

BACKGROUND:The Unified Parkinson's Disease Rating Scale (UPDRS) is the "gold standard" assessment tool for characterizing impairments in persons with Parkinson's disease (PD); however, this scale's ability to predict functional capabilities across different functional tasks has not been adequately assessed in persons with early-stage PD. METHODS:Thirty persons with PD within 3 years of diagnosis and without motor fluctuation performed self-selected walking, fast walking, and sit-to-stand and stair-climbing tasks. Pearson's correlation coefficients were used to calculate correlations with a standard UPDRS examination (P<.05). Simple linear regression models were used to fit each functional performance outcome measure with the UPDRS total predictor scores. RESULTS:The correlations between the UPDRS motor (section III), UPDRS total scores, and all timed functional performance measures were fair to good (range, 0.45-0.57). Conversely, only greater self-selected time to walk 50 ft correlated with a higher UPDRS activities of daily living (II) score (r=.386; P<.05). CONCLUSIONS:The UPDRS motor (III) and total scores may be good predictors of overall lower extremity function in persons with early-stage PD. Understanding the relationships between UPDRS scores and functional capabilities may allow clinicians to better quantify early physical functioning, longitudinally assess disease progression, and assess the efficacy of interventions.

authors

Song J,Fisher BE,Petzinger G,Wu A,Gordon J,Salem GJ

doi

10.1177/1545968309332878

subject

Has Abstract

pub_date

2009-09-01 00:00:00

pages

657-61

issue

7

eissn

1545-9683

issn

1552-6844

pii

1545968309332878

journal_volume

23

pub_type

杂志文章
  • A Critical Evaluation of the Methodological Obstacles to Translating Cell-Based Research Into an Effective Treatment for People With Parkinson's Disease.

    abstract::The remarkable scientific and technological advances in the field of cell research have not been translated into viable restorative therapies for brain disorders. In this article, we examine the best available evidence for the clinical efficacy of reconstructive intracerebral transplantation in people with Parkinson's...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968316635277

    authors: Polgar S,Karimi L,Buultjens M,Morris ME

    更新日期:2016-10-01 00:00:00

  • Defining the role of sensation, strength, and prehension for upper limb function in cervical spinal cord injury.

    abstract:BACKGROUND:Upper limb function plays a significant role in enhancing independence for individuals with tetraplegia. However, there is limited knowledge about the specific input of sensorimotor deficits on upper limb function. Thus the theoretical framework designed to develop the Graded Redefined Assessment of Strength...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968313490998

    authors: Kalsi-Ryan S,Beaton D,Curt A,Duff S,Jiang D,Popovic MR,Rudhe C,Fehlings MG,Verrier MC

    更新日期:2014-01-01 00:00:00

  • Efficacy of short-term FK506 administration on accelerating nerve regeneration.

    abstract:BACKGROUND:The slow rate of nerve regeneration following injury can cause extended muscle denervation, leading to irreversible muscle atrophy, fibrosis, and destruction of motor endplates. The immunosuppressant FK506 (tacrolimus) has been shown to accelerate the rate of nerve regeneration and functional recovery. Howev...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/1545968311431965

    authors: Yan Y,Sun HH,Hunter DA,Mackinnon SE,Johnson PJ

    更新日期:2012-07-01 00:00:00

  • Rehabilitation of gait speed after stroke: a critical review of intervention approaches.

    abstract:PURPOSE:Walking speed is a cardinal indicator of poststroke gait performance; however, no consensus exists regarding the optimal treatment method(s) for its enhancement. The most widely accepted criterion for establishing the contribution of treatment to walking speed is the gain in speed. The actual speed, however, at...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,评审

    doi:10.1177/1545968308315997

    authors: Dickstein R

    更新日期:2008-11-01 00:00:00

  • The effects of treadmill exercise training on hip bone density and tibial bone geometry in stroke survivors: a pilot study.

    abstract:BACKGROUND:Individuals with stroke often sustain bone loss on the hemiparetic side and are prone to fragility fractures. Exercise training may be a viable way to promote bone mineral density (BMD) and geometry in this population. OBJECTIVE:This was a pilot study to evaluate the effects of a 6-month treadmill exercise ...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968309353326

    authors: Pang MY,Lau RW

    更新日期:2010-05-01 00:00:00

  • Motor and premotor cortices in subcortical stroke: proton magnetic resonance spectroscopy measures and arm motor impairment.

    abstract:BACKGROUND:Although functional imaging and neurophysiological approaches reveal alterations in motor and premotor areas after stroke, insights into neurobiological events underlying these alterations are limited in human studies. OBJECTIVE:We tested whether cerebral metabolites related to neuronal and glial compartmen...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968312469835

    authors: Craciunas SC,Brooks WM,Nudo RJ,Popescu EA,Choi IY,Lee P,Yeh HW,Savage CR,Cirstea CM

    更新日期:2013-06-01 00:00:00

  • Social Network Mapping and Functional Recovery Within 6 Months of Ischemic Stroke.

    abstract::Objective. Stroke recovery is a multidimensional process influenced by biological and psychosocial factors. To understand the latter, we mapped the social networks of stroke patients, analyzing their changes and effects on physical function at 3 and 6 months after stroke. Methods. We used a quantitative social network...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,多中心研究

    doi:10.1177/1545968319872994

    authors: Dhand A,Lang CE,Luke DA,Kim A,Li K,McCafferty L,Mu Y,Rosner B,Feske SK,Lee JM

    更新日期:2019-11-01 00:00:00

  • Differential Poststroke Motor Recovery in an Arm Versus Hand Muscle in the Absence of Motor Evoked Potentials.

    abstract::Background. After stroke, recovery of movement in proximal and distal upper extremity (UE) muscles appears to follow different time courses, suggesting differences in their neural substrates. Objective. We sought to determine if presence or absence of motor evoked potentials (MEPs) differentially influences recovery o...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968319850138

    authors: Schambra HM,Xu J,Branscheidt M,Lindquist M,Uddin J,Steiner L,Hertler B,Kim N,Berard J,Harran MD,Cortes JC,Kitago T,Luft A,Krakauer JW,Celnik PA

    更新日期:2019-07-01 00:00:00

  • Improving Accelerometry-Based Measurement of Functional Use of the Upper Extremity After Stroke: Machine Learning Versus Counts Threshold Method.

    abstract:BACKGROUND:Wrist-worn accelerometry provides objective monitoring of upper-extremity functional use, such as reaching tasks, but also detects nonfunctional movements, leading to ambiguity in monitoring results. OBJECTIVE:Compare machine learning algorithms with standard methods (counts ratio) to improve accuracy in de...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968320962483

    authors: Lum PS,Shu L,Bochniewicz EM,Tran T,Chang LC,Barth J,Dromerick AW

    更新日期:2020-12-01 00:00:00

  • Compensation or Recovery? Altered Kinetics and Neuromuscular Synergies Following High-Intensity Stepping Training Poststroke.

    abstract:BACKGROUND:High-intensity, variable stepping training can improve walking speed in individuals poststroke, although neuromuscular strategies used to achieve faster speeds are unclear. We evaluated changes in joint kinetics and neuromuscular coordination following such training; movement strategies consistent with intac...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968318817825

    authors: Ardestani MM,Kinnaird CR,Henderson CE,Hornby TG

    更新日期:2019-01-01 00:00:00

  • Prevalence of Walking-Related Motor Fatigue in Persons With Multiple Sclerosis: Decline in Walking Distance Induced by the 6-Minute Walk Test.

    abstract:OBJECTIVE:To investigate the individual occurrence of walking-related motor fatigue in persons with multiple sclerosis (PwMS), according to disability level and disease phenotype.Study design This was a cross-sectional, multinational study.Participants They were 208 PwMS from 11 centers with Expanded Disability Status ...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,多中心研究

    doi:10.1177/1545968315597070

    authors: Leone C,Severijns D,Doležalová V,Baert I,Dalgas U,Romberg A,Bethoux F,Gebara B,Santoyo Medina C,Maamâgi H,Rasova K,Maertens de Noordhout B,Knuts K,Skjerbaek A,Jensen E,Wagner JM,Feys P

    更新日期:2016-05-01 00:00:00

  • Physiological responses to two wheelchair-racing exercise protocols.

    abstract:OBJECTIVE:This study investigated the blood lactate accumulation during two wheelchair-racing protocols. During exercise, energy is required, which causes metabolism to increase and blood lactate to accumulate. Proper training can reduce the amount of blood lactate accumulation and increase tolerance to blood lactate a...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1177/154596830101500306

    authors: Cooper RA,Baldini FD,Boninger ML,Cooper R

    更新日期:2001-01-01 00:00:00

  • Spaced Noninvasive Brain Stimulation: Prospects for Inducing Long-Lasting Human Cortical Plasticity.

    abstract::Neuroplasticity is critical for learning, memory, and recovery of lost function following neurological damage. Noninvasive brain stimulation (NIBS) techniques can induce neuroplastic changes in the human cortex that are behaviorally relevant, raising the exciting possibility that these techniques might be therapeutica...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968314562649

    authors: Goldsworthy MR,Pitcher JB,Ridding MC

    更新日期:2015-09-01 00:00:00

  • Improvement of visual search after audiovisual exploration training in hemianopic patients.

    abstract:OBJECTIVE:A variety of rehabilitation strategies have been tried in patients with chronic hemianopia and quadrantanopia. The authors compared 2 approaches of blind field exploration in those with recent onset of disease. METHODS:A total of 20 patients with visual field defects were studied between 3 and 24 weeks prima...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/1545968310372774

    authors: Keller I,Lefin-Rank G

    更新日期:2010-09-01 00:00:00

  • Auditory, Phonological, and Semantic Factors in the Recovery From Wernicke's Aphasia Poststroke: Predictive Value and Implications for Rehabilitation.

    abstract::Background. Understanding the factors that influence language recovery in aphasia is important for improving prognosis and treatment. Chronic comprehension impairments in Wernicke's aphasia (WA) are associated with impairments in auditory and phonological processing, compounded by semantic and executive difficulties. ...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968319868709

    authors: Robson H,Griffiths TD,Grube M,Woollams AM

    更新日期:2019-10-01 00:00:00

  • Recovery rates after stroke and their impact on outcome prediction.

    abstract::Current assessments do not provide reliable factors predictive of outcome from stroke for stroke survivors of intermediate age and severity of deficit. We sought to investigate whether early rate of functional improvement can facilitate prediction of functional outcome, length of stay, and disposition beyond that affo...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/154596830001400309

    authors: Ween JE,Mernoff ST,Alexander MP

    更新日期:2000-01-01 00:00:00

  • Atrophy and intramuscular fat in specific muscles of the thigh: associated weakness and hyperinsulinemia in stroke survivors.

    abstract:PURPOSE:Sarcopenia and increased fat infiltration in muscle may play a role in the functional impairment and high risk for diabetes in stroke. Our purpose was to compare muscle volume and muscle attenuation across 6 muscles of the paretic and nonparetic thigh and examine the relationships between intramuscular fat and ...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968311408920

    authors: Ryan AS,Buscemi A,Forrester L,Hafer-Macko CE,Ivey FM

    更新日期:2011-11-01 00:00:00

  • Agreed Definitions and a Shared Vision for New Standards in Stroke Recovery Research: The Stroke Recovery and Rehabilitation Roundtable Taskforce.

    abstract::The first Stroke Recovery and Rehabilitation Roundtable established a game changing set of new standards for stroke recovery research. Common language and definitions were required to develop an agreed framework spanning the four working groups: translation of basic science, biomarkers of stroke recovery, measurement ...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968317732668

    authors: Bernhardt J,Hayward KS,Kwakkel G,Ward NS,Wolf SL,Borschmann K,Krakauer JW,Boyd LA,Carmichael ST,Corbett D,Cramer SC

    更新日期:2017-09-01 00:00:00

  • Neuromechanical Differences Between Successful and Failed Sit-to-Stand Movements and Response to Rehabilitation Early After Stroke.

    abstract:BACKGROUND:Recovery of the sit-to-stand (StS) movement early after stroke could be improved by targeting physical therapy at the underlying movement deficits in those people likely to respond. AIM:To compare the movement characteristics of successful and failed StS movements in people early after stroke and identify w...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1177/1545968319846119

    authors: Kerr A,Clark A,Pomeroy VM

    更新日期:2019-05-01 00:00:00

  • Minimal detectable change and clinically important difference of the Stroke Impact Scale in stroke patients.

    abstract:OBJECTIVES:The purpose of this study was to establish the minimal detectable change (MDC) and clinically important differences (CIDs) of the physical domains of the Stroke Impact Scale (SIS) and to assess the proportions of patients' change scores exceeding the MDC and CIDs after stroke rehabilitation. METHODS:Seventy...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/1545968309356295

    authors: Lin KC,Fu T,Wu CY,Wang YH,Liu JS,Hsieh CJ,Lin SF

    更新日期:2010-06-01 00:00:00

  • Potential predictors of motor and functional outcomes after distributed constraint-induced therapy for patients with stroke.

    abstract:BACKGROUND:Selection of patients who are most and least likely to benefit from constraint-induced therapy (CIT) for the upper extremity is uncertain. OBJECTIVE:This study investigated demographic and clinical characteristics that may predict outcomes for a distributed form of CIT. METHODS:A group of 57 patients were ...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968308321773

    authors: Lin KC,Huang YH,Hsieh YW,Wu CY

    更新日期:2009-05-01 00:00:00

  • Levodopa Facilitates Prefrontal Cortex Activation During Dual Task Walking in Parkinson Disease.

    abstract::Background. Although dopaminergic medication improves dual task walking in people with Parkinson disease (PD), the underlying neural mechanisms are not yet fully understood. As prefrontal cognitive resources are involved in dual task walking, evaluation of the prefrontal cortex (PFC) is required. Objective. To investi...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968320924430

    authors: Orcioli-Silva D,Vitório R,Nóbrega-Sousa P,da Conceição NR,Beretta VS,Lirani-Silva E,Gobbi LTB

    更新日期:2020-07-01 00:00:00

  • How long is the recovery of global aphasia? Twenty-five years of follow-up in a patient with left hemisphere stroke.

    abstract:BACKGROUND:Current knowledge regarding the time course of aphasia recovery is based on observations limited to the first years after stroke. OBJECTIVE:The authors studied long-term outcome (25 years) of language in a patient with global aphasia. METHODS:A 37-year-old man with global aphasia from a large ischemic lesi...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968310368962

    authors: Smania N,Gandolfi M,Aglioti SM,Girardi P,Fiaschi A,Girardi F

    更新日期:2010-11-01 00:00:00

  • Test-retest reliability of portable metabolic monitoring after disabling stroke.

    abstract:PURPOSE:Impaired economy of gait, prevalent in chronic stroke secondary to residual gait deficits, is associated with intolerance for performing activities of daily living. Gait economy/efficiency is traditionally assessed by determining the rate of oxygen consumption during submaximal treadmill walking. However, the m...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968313497103

    authors: Stookey AD,McCusker MG,Sorkin JD,Katzel LI,Shaughnessy M,Macko RF,Ivey FM

    更新日期:2013-11-01 00:00:00

  • Boosting Cognition With Music in Patients With Disorders of Consciousness.

    abstract:BACKGROUND:Music listening conveys beneficial effects on cognitive processes in both normal and pathologic cerebral functioning. Surprisingly, no quantitative study has evaluated the potential effects of music on cognition and consciousness in patients with disorders of consciousness. OBJECTIVE:The aim of the present ...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968314565464

    authors: Castro M,Tillmann B,Luauté J,Corneyllie A,Dailler F,André-Obadia N,Perrin F

    更新日期:2015-09-01 00:00:00

  • Assessing Proprioception: A Systematic Review of Possibilities.

    abstract::Proprioception is a vital aspect of motor control and when degraded or lost can have a profound impact on function in diverse clinical populations. This systematic review aimed to identify clinically related tools to measure proprioceptive acuity, to classify the construct(s) underpinning the tools, and to report on t...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,评审

    doi:10.1177/1545968315573055

    authors: Hillier S,Immink M,Thewlis D

    更新日期:2015-11-01 00:00:00

  • Spatial and Temporal Control Contribute to Step Length Asymmetry During Split-Belt Adaptation and Hemiparetic Gait.

    abstract:BACKGROUND:Step length asymmetry (SLA) is a common hallmark of gait poststroke. Though conventionally viewed as a spatial deficit, SLA can result from differences in where the feet are placed relative to the body (step position strategy), the timing between foot strikes (step time strategy), or the velocity of the body...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968314567149

    authors: Finley JM,Long A,Bastian AJ,Torres-Oviedo G

    更新日期:2015-09-01 00:00:00

  • Roles of Lesioned and Nonlesioned Hemispheres in Reaching Performance Poststroke.

    abstract::Background. Severe poststroke arm impairment is associated with greater activation of the nonlesioned hemisphere during movement of the affected arm. The circumstances under which this activation may be adaptive or maladaptive remain unclear. Objective. To identify the functional relevance of key lesioned and nonlesio...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968319876253

    authors: Harrington RM,Chan E,Rounds AK,Wutzke CJ,Dromerick AW,Turkeltaub PE,Harris-Love ML

    更新日期:2020-01-01 00:00:00

  • Effects of Electrical Stimulation in Tinnitus Patients: Conventional Versus High-Definition tDCS.

    abstract:BACKGROUND:Contradictory results have been reported for transcranial direct current stimulation (tDCS) as treatment for tinnitus. The recently developed high-definition tDCS (HD tDCS) uses smaller electrodes to limit the excitation to the desired brain areas. OBJECTIVE:The current study consisted of a retrospective pa...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章

    doi:10.1177/1545968318787916

    authors: Jacquemin L,Shekhawat GS,Van de Heyning P,Mertens G,Fransen E,Van Rompaey V,Topsakal V,Moyaert J,Beyers J,Gilles A

    更新日期:2018-08-01 00:00:00

  • Training memory self-efficacy in the chronic stage after stroke: a randomized controlled trial.

    abstract:BACKGROUND:Stroke patients with a low memory self-efficacy (MSE) report more memory complaints than patients with a high MSE. OBJECTIVE:The aim of this study was to examine the effect of a memory-training program on MSE in the chronic phase after stroke and to identify which patients benefit most from the MSE training...

    journal_title:Neurorehabilitation and neural repair

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/1545968312455222

    authors: Aben L,Heijenbrok-Kal MH,van Loon EM,Groet E,Ponds RW,Busschbach JJ,Ribbers GM

    更新日期:2013-02-01 00:00:00