Rehabilitation and functional neuroimaging dose-response trajectories for clinical trials.

abstract：PURPOSE:Sarcopenia and increased fat infiltration in muscle may play a role in the functional impairment and high risk for diabetes in stroke. Our purpose was to compare muscle volume and muscle attenuation across 6 muscles of the paretic and nonparetic thigh and examine the relationships between intramuscular fat and ...

journal_title：Neurorehabilitation and neural repair

authors： Ryan AS,Buscemi A,Forrester L,Hafer-Macko CE,Ivey FM

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Somatosensory deficits are prevalent after stroke, but effective interventions are limited. Brain stimulation of the contralesional primary somatosensory cortex (S1) is a promising adjunct to peripherally administered rehabilitation therapies. OBJECTIVE:To assess short-term effects of repetitive transcrania...

journal_title：Neurorehabilitation and neural repair

authors： Pundik S,Skelly M,McCabe J,Akbari H,Tatsuoka C,Plow EB

更新日期：2021-01-29 00:00:00

abstract：BACKGROUND:Our ability to sense movement is essential for motor control; however, the impact of kinesthesia deficits on functional recovery is not well monitored in the spinal cord injury (SCI) population. One problem is the lack of accurate and reliable tools to measure kinesthesia. OBJECTIVE:The purpose of this stud...

journal_title：Neurorehabilitation and neural repair

authors： Chisholm AE,Domingo A,Jeyasurya J,Lam T

更新日期：2016-03-01 00:00:00

abstract：:Background The reliable stratification of homogeneous subgroups and the prediction of future clinical outcomes within heterogeneous neurological disorders is a particularly challenging task. Nonetheless, it is essential for the implementation of targeted care and effective therapeutic interventions. Objective This stu...

journal_title：Neurorehabilitation and neural repair

authors： Tanadini LG,Steeves JD,Hothorn T,Abel R,Maier D,Schubert M,Weidner N,Rupp R,Curt A

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Functional electrical stimulation therapy (FET) has a potential to improve voluntary grasping among individuals with tetraplegia secondary to traumatic spinal cord injury (SCI). OBJECTIVE:This single-site, randomized controlled trial examined the efficacy of 40 hours of FET with conventional occupational th...

journal_title：Neurorehabilitation and neural repair

authors： Popovic MR,Kapadia N,Zivanovic V,Furlan JC,Craven BC,McGillivray C

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Dysphagia diagnosis is limited by our inability to evaluate the underlying neuromuscular pathology of swallowing. A novel approach using pharyngeal surface electromyography (PsEMG) has been reported in the literature. OBJECTIVE:Three exploratory projects were undertaken to provide data toward the validation...

journal_title：Neurorehabilitation and neural repair

authors： Doeltgen SH,Hofmayer A,Gumbley F,Witte U,Moran C,Carroll G,Huckabee ML

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Music listening conveys beneficial effects on cognitive processes in both normal and pathologic cerebral functioning. Surprisingly, no quantitative study has evaluated the potential effects of music on cognition and consciousness in patients with disorders of consciousness. OBJECTIVE:The aim of the present ...

journal_title：Neurorehabilitation and neural repair

authors： Castro M,Tillmann B,Luauté J,Corneyllie A,Dailler F,André-Obadia N,Perrin F

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Peripheral axon regeneration is improved when the nerve lesion under consideration has recently been preceded by another nerve injury. This is known as the conditioning lesion effect (CLE). While the CLE is one of the most robust and well characterized means to enhance motor axon regeneration in experimental...

journal_title：Neurorehabilitation and neural repair

authors： Franz CK,Puritz A,Jordan LA,Chow J,Ortega JA,Kiskinis E,Heckman CJ

更新日期：2018-08-01 00:00:00

abstract：:The goal of the present study was to examine factors affecting motor impairment and recovery in a primate model of cortical infarction. Microelectrode stimulation techniques were used to delineate the hand representation in the primary motor cortex (M1). Microinfarcts affecting approximately 30% of the hand representa...

journal_title：Neurorehabilitation and neural repair

authors： Heddings AA,Friel KM,Plautz EJ,Barbay S,Nudo RJ

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Objective measures of functional walking remain scarce for individuals with incomplete spinal cord injury (ISCI). Hence, the authors developed the Spinal Cord Injury Functional Ambulation Profile (SCI-FAP), which encompasses the timed performance of 7 tasks, such as walking and negotiating obstacles, doors, ...

journal_title：Neurorehabilitation and neural repair

authors： Musselman K,Brunton K,Lam T,Yang J

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:A randomized clinical has shown the effectiveness of intramuscular electrical stimulation for the treatment of poststroke shoulder pain. OBJECTIVE:Identify predictors of treatment success and assess the impact of the strongest predictor on outcomes. METHOD:This is a secondary analysis of a multisite random...

journal_title：Neurorehabilitation and neural repair

authors： Chae J,Ng A,Yu DT,Kirsteins A,Elovic EP,Flanagan SR,Harvey RL,Zorowitz RD,Fang ZP

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Fatigue is a debilitating symptom in multiple sclerosis (MS). Previous studies showed no association between fatigue as perceived by the patient and physiological measures of fatigability. OBJECTIVE:The authors investigated associations between perceived fatigue and measures of fatigability after correction...

journal_title：Neurorehabilitation and neural repair

authors： Steens A,de Vries A,Hemmen J,Heersema T,Heerings M,Maurits N,Zijdewind I

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:This study investigated the course and relationship between investigator-determined and patient-reported level of independence within the first year after spinal cord injury (SCI). The authors examined variables that contributed to these scores. METHODS:In this observational cohort study, 73 patients with tr...

journal_title：Neurorehabilitation and neural repair

authors： van Hedel HJ,Dokladal P,Hotz-Boendermaker S,EM-SCI Study Group.

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Dual tasking can interfere with activity after stroke. OBJECTIVE:The authors examined the interactions between 3 different cognitive tasks and the swing and double-limb support (DLS) components of the gait cycle in community-dwelling individuals poststroke. METHODS:Acquisition of cognitive and gait data we...

journal_title：Neurorehabilitation and neural repair

authors： Plummer-D'Amato P,Altmann LJ,Behrman AL,Marsiske M

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The neural correlates of training-induced improvements of cognitive functions after brain damage remain still scarcely understood. In the specific case of aphasia, although several investigations have addressed the issue of the neural substrates of functional recovery, only a few studies have attempted to as...

journal_title：Neurorehabilitation and neural repair

authors： Vitali P,Abutalebi J,Tettamanti M,Danna M,Ansaldo AI,Perani D,Joanette Y,Cappa SF

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to establish the minimal detectable change (MDC) and clinically important differences (CIDs) of the physical domains of the Stroke Impact Scale (SIS) and to assess the proportions of patients' change scores exceeding the MDC and CIDs after stroke rehabilitation. METHODS:Seventy...

journal_title：Neurorehabilitation and neural repair

authors： Lin KC,Fu T,Wu CY,Wang YH,Liu JS,Hsieh CJ,Lin SF

更新日期：2010-06-01 00:00:00

abstract：:Proprioception is a vital aspect of motor control and when degraded or lost can have a profound impact on function in diverse clinical populations. This systematic review aimed to identify clinically related tools to measure proprioceptive acuity, to classify the construct(s) underpinning the tools, and to report on t...

journal_title：Neurorehabilitation and neural repair

authors： Hillier S,Immink M,Thewlis D

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Limited data are available about the effectiveness of early rehabilitation after stroke. OBJECTIVE:This is the 1st randomized controlled trial of constraint-induced movement therapy (CIMT) in subacute stroke to investigate neurophysiologic mechanisms and long-term outcome. METHODS:Within 2 weeks after stro...

journal_title：Neurorehabilitation and neural repair

authors： Boake C,Noser EA,Ro T,Baraniuk S,Gaber M,Johnson R,Salmeron ET,Tran TM,Lai JM,Taub E,Moye LA,Grotta JC,Levin HS

更新日期：2007-01-01 00:00:00

abstract：:A major problem in neurorehabilitation is the lack of objective outcomes to measure movement quality. Movement quality features, such as coordination and stability, are essential for everyday motor actions. These features allow reacting to continuously changing environment or to resist external perturbations. Neurolog...

journal_title：Neurorehabilitation and neural repair

authors： Solnik S,Furmanek MP,Piscitelli D

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Current available therapies for Parkinson disease (PD) have strong limitations, and patients usually present with refractory symptoms despite all efforts. Deep brain stimulation (DBS), which has been used in PD patients for decades (since 1987), has best indications for symptoms like tremor, motor fluctuatio...

journal_title：Neurorehabilitation and neural repair

authors： Garcia BB,Junior ER,Araújo MFP,Simplício H

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:The use of exercise in amyotrophic lateral sclerosis (ALS) is controversial. Although moderate exercise appears to be beneficial for limb muscles in ALS, the effects of exercise on bulbar muscles such as the tongue have not been studied. OBJECTIVE:To determine the effects of tongue force training on bulbar ...

journal_title：Neurorehabilitation and neural repair

authors： Ma D,Shuler JM,Kumar A,Stanford QR,Tungtur S,Nishimune H,Stanford JA

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Hemiparetic gait following stroke requires substantial energy consumption, which would promote deconditioning and disability. Optimal modalities for decreasing this energy cost remain challenging. Excessive energy consumption, however, seems to be mainly due to extra positive muscle work to substantially lif...

journal_title：Neurorehabilitation and neural repair

authors： Massaad F,Lejeune TM,Detrembleur C

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:The assessment of rehabilitation efficacy in spinal cord injury (SCI) should be based on a combination of neurological and functional outcome measures. The Spinal Cord Independence Measure II (SCIM II) is an independence scale that was specifically developed for subjects with SCI. However, little is known ab...

journal_title：Neurorehabilitation and neural repair

authors： Wirth B,van Hedel HJ,Kometer B,Dietz V,Curt A

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Cortical networks underlying motor imagery are functionally close to motor performance networks and can be activated by patients with severe motor disabilities. OBJECTIVE:The aim of the study was to examine the longitudinal effect of progressive motoneuron degeneration on cortical representation of motor im...

journal_title：Neurorehabilitation and neural repair

authors： Lulé D,Diekmann V,Kassubek J,Kurt A,Birbaumer N,Ludolph AC,Kraft E

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Stroke patients with a low memory self-efficacy (MSE) report more memory complaints than patients with a high MSE. OBJECTIVE:The aim of this study was to examine the effect of a memory-training program on MSE in the chronic phase after stroke and to identify which patients benefit most from the MSE training...

journal_title：Neurorehabilitation and neural repair

authors： Aben L,Heijenbrok-Kal MH,van Loon EM,Groet E,Ponds RW,Busschbach JJ,Ribbers GM

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This study investigated the relative effects of distributed constraint-induced therapy (CIT) and bilateral arm training (BAT) on motor performance, daily function, functional use of the affected arm, and quality of life in patients with hemiparetic stroke. METHODS:A total of 60 patients were r...

journal_title：Neurorehabilitation and neural repair

authors： Lin KC,Chang YF,Wu CY,Chen YA

更新日期：2009-06-01 00:00:00

abstract：:Implementation is the use of strategies to adopt and integrate evidence-based health interventions and to change practice patterns. In their article, "Implementation-the missing link in the research translation pipeline," Lynch et al1 report that only a small fraction of published stroke rehabilitation research in lea...

journal_title：Neurorehabilitation and neural repair

authors： Morrato EH

更新日期：2018-09-01 00:00:00

abstract：:Background. High-intensity repetitive training is challenging to provide poststroke. Robotic approaches can facilitate such training by unweighting the limb and/or by improving trajectory control, but the extent to which these types of assistance are necessary is not known. Objective. The purpose of this study was to ...

journal_title：Neurorehabilitation and neural repair

authors： Raghavan P,Bilaloglu S,Ali SZ,Jin X,Aluru V,Buckley MC,Tang A,Yousefi A,Stone J,Agrawal SK,Lu Y

更新日期：2020-02-01 00:00:00

abstract：:The remarkable scientific and technological advances in the field of cell research have not been translated into viable restorative therapies for brain disorders. In this article, we examine the best available evidence for the clinical efficacy of reconstructive intracerebral transplantation in people with Parkinson's...

journal_title：Neurorehabilitation and neural repair

authors： Polgar S,Karimi L,Buultjens M,Morris ME

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:and purpose. Mental practice (MP), which involves cognitive rehearsal of physical movements, is a noninvasive, inexpensive method of enabling repetitive, task-specific practice (RTP). Recent, randomized controlled data suggest that MP, when combined with an RTP therapy program, increases affected arm use and...

journal_title：Neurorehabilitation and neural repair

authors： Page SJ,Szaflarski JP,Eliassen JC,Pan H,Cramer SC

更新日期：2009-05-01 00:00:00