Reducing mitochondrial decay with mitochondrial nutrients to delay and treat cognitive dysfunction, Alzheimer's disease, and Parkinson's disease.

abstract：OBJECTIVES:Stress in known to alter hormonal systems. Pharmacological doses of tryptophan, the essential amino acid precursor of serotonin, increase circulating leptin and decrease ghrelin in normal healthy adults. Because systemically injected leptin inhibits stress-induced behavioral deficits and systemically injecte...

journal_title：Nutritional neuroscience

authors： Gul S,Saleem D,Haleem MA,Haleem DJ

更新日期：2019-06-01 00:00:00

abstract：:We examined Dohan's hypothesis that schizophrenia is associated with the absorption of "exorphins" contained in gluten and casein. In addition, because of the work of Reichelt et al. (Reichelt, K.L., Saelid, G., Lindback, J. and Orbeck, H. (1986) Biological Psychiatry 21:1279-1290) and Rodriguez et al. (Rodriguez, Tra...

journal_title：Nutritional neuroscience

authors： Cade R,Privette M,Fregly M,Rowland N,Sun Z,Zele V,Wagemaker H,Edelstein C

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVES:To investigate the effects of Calpis sour milk whey, a Lactobacillus helveticus-fermented milk product, on learning and memory. METHODS:We evaluated improvement in scopolamine-induced memory impairment using the spontaneous alternation behaviour test, a measure of short-term memory. We also evaluated learni...

journal_title：Nutritional neuroscience

authors： Ohsawa K,Uchida N,Ohki K,Nakamura Y,Yokogoshi H

更新日期：2015-07-01 00:00:00

abstract：:Food intake decreases and a conditioned taste aversion is induced when rats are fed a diet that is devoid of an indispensable amino acid. The purpose of this study was to characterize the meal patterns associated with (1) the onset of anorexia after the initial recognition of a threonine deficiency and (2) after the d...

journal_title：Nutritional neuroscience

authors： Feurté S,Tomé D,Gietzen DW,Even PC,Nicolaïdis S,Fromentin G

更新日期：2002-09-01 00:00:00

abstract：:Background/aim: Vitamin D has been hypothesized to be main regulator of the aging rate, alongside evidences support its role in neuroprotection. However, data about the protective role of vitamin D against neurophysiologic alterations associated with brain aging is limited. This study investigated the possible protect...

journal_title：Nutritional neuroscience

authors： Khairy EY,Attia MM

更新日期：2019-09-16 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine the influence of dietary macronutrient composition on central NPY's orexigenic effect in chicks. METHODS:Day-of-hatch chicks were fed one of three diets (3000 kcal ME/kg) ad libitum from hatch: high carbohydrate (HC), high fat (HF; 30% ME derived from soybean oil)...

journal_title：Nutritional neuroscience

authors： McConn BR,Cline MA,Gilbert ER

更新日期：2018-07-01 00:00:00

abstract：:Background: The two metabolites of vitamin D; serum 25-hydroxyvitamin D3 (25(OH)D3) and D2 (25(OH)D2), and their independent roles in mood regulation are unexplored. This study aims to examine 25(OH)D3 and 25(OH)D2 and their interplay with depression symptoms. Materials and Methods: Utilizing data from the U.S. Nation...

journal_title：Nutritional neuroscience

authors： Bigman G

更新日期：2020-07-20 00:00:00

abstract：OBJECTIVE:This study was designed to review the effect of chronic aluminium exposure on interleukin-6 (IL-6) secretion in the posterior brain and test the putative modulating effect of fenugreek seeds. METHODS:Female Wistar rats were divided into four groups: control; AlCl3 during 5 months (500 mg/kg body weight, intr...

journal_title：Nutritional neuroscience

authors： Belaïd-Nouira Y,Bakhta H,Samoud S,Trimech M,Haouas Z,Ben Cheikh H

更新日期：2013-09-01 00:00:00

abstract：:Introduction: The brain plays an important regulatory role in directing energy homeostasis and eating behavior. The increased ingestion of sugars and sweeteners over the last decades makes investigating the effects of these substances on the regulatory function of the brain of particular interest. We investigated whol...

journal_title：Nutritional neuroscience

authors： Van Opstal AM,Hafkemeijer A,van den Berg-Huysmans AA,Hoeksma M,Mulder TPJ,Pijl H,Rombouts SARB,van der Grond J

更新日期：2019-07-10 00:00:00

abstract：BACKGROUND/OBJECTIVES:Nervous system damage is one of the consequences of oral exposure to waterborne inorganic arsenic. In this work, the role of oxidative status in the neurotoxicity of arsenic and the possible role of two foodborne antioxidants in ameliorating arsenic-related oxidative stress were investigated. MET...

journal_title：Nutritional neuroscience

authors： Sárközi K,Papp A,Horváth E,Máté Z,Ferencz Á,Hermesz E,Krisch J,Paulik E,Szabó A

更新日期：2016-01-01 00:00:00

abstract：:Objectives: A strong rise of the fructose content in the human diet occurred in the last decade, as corn syrup is widely used as a sweetener for beverages and processed food. Since young people make a widespread consumption of added sugars, we evaluated the effects of a two weeks fructose-rich diet on brain redox home...

journal_title：Nutritional neuroscience

authors： Spagnuolo MS,Bergamo P,Crescenzo R,Iannotta L,Treppiccione L,Iossa S,Cigliano L

更新日期：2020-04-01 00:00:00

abstract：:This study aimed to investigate the effect of a single injection of pilocarpine upon the phenomenon of cortical spreading depression (SD), in adult rats submitted to early malnutrition and/or to REM-sleep deprivation for 72h prior to the SD-recordings. The SD was recorded continuously for 3-4h in 13 well-nourished (W)...

journal_title：Nutritional neuroscience

authors： De Vasconcelos CA,De Oliveira JA,De Oliveira Costat LA,Guedes RC

更新日期：2004-06-01 00:00:00

abstract：:To clarify whether L-ornithine and/or its metabolite involves sedative and hypnotic effects under social separation stress, the effects of intracerebroventricular (i.c.v.) injection of L-ornithine and polyamines (putrescine, spermidine and spermine) were compared in chicks. Birds were injected i.c.v. with 0.5 mumol of...

journal_title：Nutritional neuroscience

authors： Kurauchi I,Shigemi K,Kabuki Y,Hamasu K,Yamane H,Aoki M,Kawada Y,Morishita K,Denbow DM,Furuse M

更新日期：2010-02-01 00:00:00

abstract：:Background: The aetiology of Attention Deficit Hyperactivity Disorder (ADHD) continues to be debated, although several contributing factors have been acknowledged. Objective: Assess the association between weight, birth attributes, exercise and sleep habits, dietary intake and adherence to a Mediterranean diet, and im...

journal_title：Nutritional neuroscience

authors： San Mauro Martin I,Sanz Rojo S,Garicano Vilar E,González Cosano L,Conty de la Campa R,Blumenfeld Olivares JA

更新日期：2019-09-03 00:00:00

abstract：:Objectives: This study was designed to investigate the vitamin A (VA) and vitamin D (VD) levels in children with autism spectrum disorders (ASD) and to determine whether co-deficiency of VA and VD exacerbates clinical symptoms in autistic children. Methods: The Autism Behavior Checklist, Childhood Autism Rating Scale ...

journal_title：Nutritional neuroscience

authors： Guo M,Zhu J,Yang T,Lai X,Lei Y,Chen J,Li T

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVES:Genistein is a plant-derived estrogenic isoflavone commonly found in dietary and therapeutic supplements, due to its potential health benefits. Growth hormone-releasing hormone (GHRH) and somatostatin (SS) are neurosecretory peptides synthesized in neurons of the hypothalamus and regulate the growth hormone ...

journal_title：Nutritional neuroscience

authors： Trifunović S,Manojlović-Stojanoski M,Ristić N,Nestorović N,Medigović I,Živanović J,Milošević V

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:Western-style diets high in saturated fat and refined carbohydrate have been shown to alter gut microbiota as well as being associated with altered behaviour and learning ability. The objective of this study was to determine the effects of short-term intake of a Western-style diet on intestinal cytokine expr...

journal_title：Nutritional neuroscience

authors： Ohland CL,Pankiv E,Baker G,Madsen KL

更新日期：2016-10-01 00:00:00

abstract：:Objectives: Unfavorable lactation influences brain excitability and behavioral reactions in adults. Administration early in life of the cholinergic agonist, pilocarpine, even at non-convulsive doses, alters the brain excitability-related phenomenon known as cortical spreading depression (CSD), and produce anxiogenic-l...

journal_title：Nutritional neuroscience

authors： Benevides RDL,de-Lima SMV,Chagas CL,de Lima CF,Abadie-Guedes R,Guedes RCA

更新日期：2020-09-11 00:00:00

abstract：:The antiperoxidative properties of alpha-mangostin, a xanthone isolated from mangosteen fruit, were tested for the first time in nerve tissue exposed to different toxic insults. Two reliable biological preparations (rat brain homogenates and synaptosomal P2 fractions) were exposed to the toxic actions of a free radica...

journal_title：Nutritional neuroscience

authors： Márquez-Valadez B,Lugo-Huitrón R,Valdivia-Cerda V,Miranda-Ramírez LR,Pérez-De La Cruz V,González-Cuahutencos O,Rivero-Cruz I,Mata R,Santamaría A,Pedraza-Chaverrí J

更新日期：2009-02-01 00:00:00

abstract：:Adult female rats, receiving a low protein diet at perinatal age and then recovered with balanced chow (D rats), were evaluated in the Open Field Drink Test (OFDT), after different acute and chronic treatments with benzodiazepines (BZD) ligands, as compared with control (C) female rats. Control and D rats showed simil...

journal_title：Nutritional neuroscience

authors： Borghese CM,Córdoba NE,Arolfo MP,Orsingher OA

更新日期：1998-01-01 00:00:00

abstract：:Newborn rats maintain mother-litter bonds by using olfactory signals. At birth, units in the olfactory glomeruli (OG) are immature and vulnerable to noxious epigenetic factors like undernutrition. Because little is known about the effects of neonatal undernutrition upon the OG morphological organization, different OG ...

journal_title：Nutritional neuroscience

authors： Frias C,Torrero C,Regalado M,Salas M

更新日期：2006-02-01 00:00:00

abstract：:A high-fat diet (HFD) during pregnancy influences the neurodevelopment of progeny, particularly in the hippocampus, a brain region involved in cognitive processes. The hippocampus has high levels of leptin receptors (Ob-R) that participate in synaptic plasticity. This study examined the effect of maternal HFD during g...

journal_title：Nutritional neuroscience

authors： Cortés-Álvarez NY,Vuelvas-Olmos CR,Pinto-González MF,Guzmán-Muñiz J,Gonzalez-Perez O,Moy-López NA

更新日期：2020-02-19 00:00:00

abstract：BACKGROUND:Differences in the composition of control diets may confound outcomes in studies investigating dietary effects. OBJECTIVE:We compared the effects of two control diets commonly used in mice studies, chow (SD) and a purified low-fat diet (LFD), in relation to a chronic high-fat diet (HFD). We hypothesized tha...

journal_title：Nutritional neuroscience

authors： Almeida-Suhett CP,Scott JM,Graham A,Chen Y,Deuster PA

更新日期：2019-01-01 00:00:00

abstract：:Objective: Possible effects of the vagus inhibition and stimulation on the hypothalamic nuclei, myenteric plexes and the vagus nerve were investigated. Methods: The female rats divided to the inhibition (INH), stimulation (STI) and, sham (SHAM) groups were fed with high fat diet (including 40% of energy from animal fa...

journal_title：Nutritional neuroscience

authors： Alkan I,Altunkaynak BZ,Kivrak EG,Kaplan AA,Arslan G

更新日期：2020-10-09 00:00:00

abstract：PURPOSE:The aim of this study was investigating the effect of omega-3 fatty acids (ω-3 FAs) on brain-derived neurotrophic factor (BDNF) gene expression, using in vivo and in vitro models, to unravel the potential mechanisms of polyunsaturated fatty acids use in obesity. MATERIALS AND METHODS:Twenty-nine Sprague-Dawley...

journal_title：Nutritional neuroscience

authors： Abdel-Maksoud SM,Hassanein SI,Gohar NA,Attia SMM,Gad MZ

更新日期：2017-10-01 00:00:00

abstract：:This symposium examined current trends in neuroscience and developmental psychology as they apply to assessing the effects of nutrients on brain and behavioral development of 0-6-year-olds. Although the spectrum of nutrients with brain effects has not changed much in the last 25 years, there has been an explosion in n...

journal_title：Nutritional neuroscience

authors： Rosales FJ,Zeisel SH

更新日期：2008-06-01 00:00:00

abstract：:Cognitive and motor performance are critical in many circumstances and are impaired by sleep deprivation. We administered placebo, tyrosine 150 mg/kg, caffeine 300 mg/70 kg, phentermine 37.5 mg and D-amphetamine 20 mg at 15.30 h following overnight sleep deprivation and compare their effects on cognitive and motor per...

journal_title：Nutritional neuroscience

authors： Magill RA,Waters WF,Bray GA,Volaufova J,Smith SR,Lieberman HR,McNevin N,Ryan DH

更新日期：2003-08-01 00:00:00

abstract：:Organophosphorus compounds are widely used in agriculture. Epidemiological studies propose that pesticide exposure is a risk factor for Alzheimer's disease (AD), but the mechanisms are unclear. Here, we investigated the impact of malathion exposure on the cognitive ability and the underlying mechanisms in rats. Moreov...

journal_title：Nutritional neuroscience

authors： Mohammadzadeh L,Abnous K,Razavi BM,Hosseinzadeh H

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the association between cerebral infarction (CI), nutritional status, and depression. METHODS:Subjects with and without CI (n = 146; 73 CI vs. 73 non-CI) were recruited from Kyung Hee University Medical Center (Seoul, Korea) and were matched according to age and gende...

journal_title：Nutritional neuroscience

authors： Lim HJ,Choue R

更新日期：2012-01-01 00:00:00

abstract：:Studies using traditional treatment strategies for mild traumatic brain injury (TBI) have produced limited clinical success. Interest in treatment for mild TBI is at an all time high due to its association with the development of chronic traumatic encephalopathy and other neurodegenerative diseases, yet therapeutic op...

journal_title：Nutritional neuroscience

authors： Lucke-Wold BP,Logsdon AF,Nguyen L,Eltanahay A,Turner RC,Bonasso P,Knotts C,Moeck A,Maroon JC,Bailes JE,Rosen CL

更新日期：2018-02-01 00:00:00