Association between poor nutritional status and severe depression in Korean cerebral infarction patients.

Abstract:

OBJECTIVE:The purpose of this study was to assess the association between cerebral infarction (CI), nutritional status, and depression. METHODS:Subjects with and without CI (n = 146; 73 CI vs. 73 non-CI) were recruited from Kyung Hee University Medical Center (Seoul, Korea) and were matched according to age and gender. The subjects' medical histories, health-related behavioral habits, food intake, nutritional assessment, and depression status were analyzed. RESULTS:The prevalence of hypertension or diabetes were much higher in subjects in the CI group than in the non-CI group (P < 0.001). Subjects with CI registered lower dietary intakes of potassium, dietary fiber, fish, fruits, and vegetables than non-CI subjects (P < 0.05). By the mini-nutritional assessment (MNA) classification, malnutrition affected 57.5% of subjects in the CI group, but none of the subjects in the non-CI group (P < 0.001). The average Beck depression inventory (BDI) score was 43.6 ± 7.7 points in the CI group and 20.6 ± 13.1 points in the non-CI group (P < 0.001). Higher MNA scores (well-nourished status) were inversely associated with CI prevalence (odds ratio (OR) = 0.23; 95% CI: 0.07, 0.79) after controlling for age, gender, medical history, and health-related factors, whereas BDI was not associated with CI prevalence (OR = 1.32; 95% CI: 0.90, 1.94). DISCUSSION:CI patients had several comorbidities, inappropriate health-related behavioral habits, malnourished status, and severe depression prior to CI onset. Indices of well-nourished status were inversely associated with CI. Accordingly, it would be desirable to develop a protocol for medical nutrition therapy in CI patients to improve nutritional status.

journal_name

Nutr Neurosci

journal_title

Nutritional neuroscience

authors

Lim HJ,Choue R

doi

10.1179/1476830511Y.0000000023

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

25-30

issue

1

eissn

1028-415X

issn

1476-8305

journal_volume

15

pub_type

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