Lesions of the lateral parabrachial area block the aversive component and induced-flavor preference for the delayed intragastric administration of nutrients in rats: effects on subsequent food and water intake.

Abstract:

:The aim of this study was to examine the function of the lateral parabrachial area (LPB) in relation to the intragastric administration of nutrients. The consumption of flavors associated with intragastric nutrient administration and the subsequent food and water intake were measured in rats with lesions in the LPB. The results showed that bilateral LPB lesions prevented development of aversions and induced flavor preference when there was a delay between the presentation of a flavor and the intragastric administration of nutrients. However, these lesions did not disrupt development of the aversive process when there was no delay between the presentations. Likewise, the LPB lesions increased subsequent food intake when there was a delay but not when there was no delay between the presentations. In contrast, the water intake was reduced in both situations. These results are interpreted in terms of a dual visceral system for processing the intragastric effects of foods.

journal_name

Nutr Neurosci

journal_title

Nutritional neuroscience

authors

Zafra MA,Simón MJ,Molina F,Puerto A

doi

10.1080/10284150600576655

subject

Has Abstract

pub_date

2005-10-01 00:00:00

pages

297-307

issue

5-6

eissn

1028-415X

issn

1476-8305

journal_volume

8

pub_type

杂志文章
  • A novel insight on chronic AlCl3 neurotoxicity through IL-6 and GFAP expressions: modulating effect of functional food fenugreek seeds.

    abstract:OBJECTIVE:This study was designed to review the effect of chronic aluminium exposure on interleukin-6 (IL-6) secretion in the posterior brain and test the putative modulating effect of fenugreek seeds. METHODS:Female Wistar rats were divided into four groups: control; AlCl3 during 5 months (500 mg/kg body weight, intr...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1179/1476830512Y.0000000048

    authors: Belaïd-Nouira Y,Bakhta H,Samoud S,Trimech M,Haouas Z,Ben Cheikh H

    更新日期:2013-09-01 00:00:00

  • Control diet in a high-fat diet study in mice: Regular chow and purified low-fat diet have similar effects on phenotypic, metabolic, and behavioral outcomes.

    abstract:BACKGROUND:Differences in the composition of control diets may confound outcomes in studies investigating dietary effects. OBJECTIVE:We compared the effects of two control diets commonly used in mice studies, chow (SD) and a purified low-fat diet (LFD), in relation to a chronic high-fat diet (HFD). We hypothesized tha...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2017.1349359

    authors: Almeida-Suhett CP,Scott JM,Graham A,Chen Y,Deuster PA

    更新日期:2019-01-01 00:00:00

  • Vitamin D metabolites, D3 and D2, and their independent associations with depression symptoms among adults in the United States.

    abstract::Background: The two metabolites of vitamin D; serum 25-hydroxyvitamin D3 (25(OH)D3) and D2 (25(OH)D2), and their independent roles in mood regulation are unexplored. This study aims to examine 25(OH)D3 and 25(OH)D2 and their interplay with depression symptoms. Materials and Methods: Utilizing data from the U.S. Nation...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2020.1794422

    authors: Bigman G

    更新日期:2020-07-20 00:00:00

  • Dietary choline during periadolescence attenuates cognitive damage caused by neonatal maternal separation in male rats.

    abstract:OBJECTIVES:Choline (Ch) is an essential nutrient that acts as a cognitive facilitator when administered during perinatal periods, and it has been recognised as a 'pharmacological' agent that can ease cognitive dysfunctions provoked by exposure to damaging stimuli during early developmental stages. The aim of the presen...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2015.1126444

    authors: Moreno Gudiño H,Carías Picón D,de Brugada Sauras I

    更新日期:2017-07-01 00:00:00

  • Beneficial effects of a protein free, high carbohydrate meal on rat coping behavior and neurotransmitter levels during heat stress.

    abstract::This study examined effects of a single protein-free (PROT-free), high carbohydrate meal (0% protein, 82% carbohydrate) or control meal (20% protein, 62% carbohydrate) on coping behavior and neurotransmitter levels of male Fischer 344 rats. Meals varying in protein/carbohydrate ratio differentially affect transport of...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/10284150400017330

    authors: Yeghiayan SK,Georgelis JH,Maher TJ,Lieberman HR

    更新日期:2004-10-01 00:00:00

  • Differential Effects of Prenatal Protein Malnutrition and Prenatal Cocaine on Radial Arm Maze Performance in Adult Male Rats.

    abstract::The effects of prenatal cocaine and protein malnutrition were examined on acquisition of the radial arm maze in adult male Sprague-Dawley rats whose mothers were provided with a 6% casein, a 25% casein or a standard chow diet and cocaine (30mg/kg) or saline injections beginning 5 weeks prior to mating and continuing t...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.1999.11747269

    authors: Shumsky JS,Shultz PL,Galler JR,Tonkiss J

    更新日期:1999-01-01 00:00:00

  • Malnutrition and REM-sleep deprivation modulate in rats the impairment of spreading depression by a single sub-convulsing dose of pilocarpine.

    abstract::This study aimed to investigate the effect of a single injection of pilocarpine upon the phenomenon of cortical spreading depression (SD), in adult rats submitted to early malnutrition and/or to REM-sleep deprivation for 72h prior to the SD-recordings. The SD was recorded continuously for 3-4h in 13 well-nourished (W)...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/10284150412331281031

    authors: De Vasconcelos CA,De Oliveira JA,De Oliveira Costat LA,Guedes RC

    更新日期:2004-06-01 00:00:00

  • The Effect of Centrally Administered Glibenclamide, Tolbutamide and Diazoxide on Feeding in Rats.

    abstract::While there are many theories on the control of feeding behavior that emphasize a role for energy substrates and their metabolism, the mechanism that couples changes in energy substrate supply and metabolism to alterations in food intake remains unclear. The purpose of the present project was to investigate the possib...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.1999.11747274

    authors: Bounds JK,Adloo AA,Harp PR,Olivier K,Roane DS

    更新日期:1999-01-01 00:00:00

  • Omega-3 PUFAs and vitamin D co-supplementation as a safe-effective therapeutic approach for core symptoms of autism spectrum disorder: case report and literature review.

    abstract::Introduction: Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by abnormal development of cognitive, social, and communicative skills. Although ASD aetiology and pathophysiology are still unclear, various nutritional factors have been investigated as potential risk factors for AS...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2018.1557385

    authors: Infante M,Sears B,Rizzo AM,Mariani Cerati D,Caprio M,Ricordi C,Fabbri A

    更新日期:2020-10-01 00:00:00

  • Improved cognitive-cerebral function in older adults with chromium supplementation.

    abstract::Insulin resistance is implicated in the pathophysiological changes associated with Alzheimer's disease, and pharmaceutical treatments that overcome insulin resistance improve memory function in subjects with mild cognitive impairment (MCI) and early Alzheimer's disease. Chromium (Cr) supplementation improves glucose d...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章,随机对照试验

    doi:10.1179/147683010X12611460764084

    authors: Krikorian R,Eliassen JC,Boespflug EL,Nash TA,Shidler MD

    更新日期:2010-06-01 00:00:00

  • The neuroprotective effects of an ethanolic turmeric (Curcuma longa L.) extract against trimethyltin-induced oxidative stress in rats.

    abstract::Introduction: Oxidative stress is known to contribute to the pathogenesis of neurodegenerative disorders. An ethanolic turmeric (Curcuma longa L.) extract containing curcumin has been reported to produce antioxidant effects. Objective: The present study aims to investigate the possible neuroprotective effects of the e...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2018.1447267

    authors: Yuliani S,Mustofa,Partadiredja G

    更新日期:2019-11-01 00:00:00

  • Brain activity and connectivity changes in response to nutritive natural sugars, non-nutritive natural sugar replacements and artificial sweeteners.

    abstract::Introduction: The brain plays an important regulatory role in directing energy homeostasis and eating behavior. The increased ingestion of sugars and sweeteners over the last decades makes investigating the effects of these substances on the regulatory function of the brain of particular interest. We investigated whol...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2019.1639306

    authors: Van Opstal AM,Hafkemeijer A,van den Berg-Huysmans AA,Hoeksma M,Mulder TPJ,Pijl H,Rombouts SARB,van der Grond J

    更新日期:2019-07-10 00:00:00

  • Oral solution of fructose promotes SREBP-1c high-expression in the hypothalamus of Wistar rats.

    abstract::Objective: We evaluate whether the consumption of fructose for 8 weeks affects enzymes and transcription factors of the lipogenic and inflammatory pathways in the hypothalamus of Wistar rats. Methods: At 30 days, the animals were divided into groups: Control (C) and Fructose (F) and maintained with free access to feed...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2018.1427659

    authors: Batista LO,Ramos VW,Rosas Fernández MA,Concha Vilca CM,Albuquerque KT

    更新日期:2019-09-01 00:00:00

  • Understanding the role of nutrition in the brain and behavioral development of toddlers and preschool children: identifying and addressing methodological barriers.

    abstract::The preschool years (i.e. 1-5 years of age) is a time of rapid and dramatic postnatal brain development (i.e. neural plasticity), and of fundamental acquisition of cognitive development (i.e. working memory, attention and inhibitory control). Also, it is a time of transition from a direct maternal mediation/selection ...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章,评审

    doi:10.1179/147683009X423454

    authors: Rosales FJ,Reznick JS,Zeisel SH

    更新日期:2009-10-01 00:00:00

  • Chronic Diazepam Administration Failed to Induce Tolerance and Withdrawal Syndrome in Perinatally Undernourished Female Rats as Measured in the Open Field Drink Test.

    abstract::Adult female rats, receiving a low protein diet at perinatal age and then recovered with balanced chow (D rats), were evaluated in the Open Field Drink Test (OFDT), after different acute and chronic treatments with benzodiazepines (BZD) ligands, as compared with control (C) female rats. Control and D rats showed simil...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.1998.11747253

    authors: Borghese CM,Córdoba NE,Arolfo MP,Orsingher OA

    更新日期:1998-01-01 00:00:00

  • Pseudotumor cerebri in pediatric age: role of obesity in the management of neurological impairments.

    abstract::Pseudotumor cerebri occurs quite rarely in the pediatric population and its clinical features differ from adults in many ways. Intracranial hypertension with papilledema should obviously be treated promptly to avoid permanent visual damage, but various more or less invasive options have been proposed over the years, f...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1179/147683008X301388

    authors: Marton E,Feletti A,Mazzucco GM,Longatti P

    更新日期:2008-02-01 00:00:00

  • Vitamin A and vitamin D deficiencies exacerbate symptoms in children with autism spectrum disorders.

    abstract::Objectives: This study was designed to investigate the vitamin A (VA) and vitamin D (VD) levels in children with autism spectrum disorders (ASD) and to determine whether co-deficiency of VA and VD exacerbates clinical symptoms in autistic children. Methods: The Autism Behavior Checklist, Childhood Autism Rating Scale ...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2017.1423268

    authors: Guo M,Zhu J,Yang T,Lai X,Lei Y,Chen J,Li T

    更新日期:2019-09-01 00:00:00

  • Ghrelin as a prominent endocrine factor in stress-induced obesity.

    abstract::Objectives: Ghrelin acts on a variety of central- and peripheral organs causing an orexigenic effect, conclusively followed by increased caloric intake. Recent studies have indicated that ghrelin's function as an orexigenic agent does not entirely reflect the full functional properties of the peptide. Specifically, gh...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2020.1863740

    authors: van Loenen MR,Geenen B,Arnoldussen IAC,Kiliaan AJ

    更新日期:2020-12-29 00:00:00

  • Spirulina and C-phycocyanin reduce cytotoxicity and inflammation-related genes expression of microglial cells.

    abstract:OBJECTIVE:Our aim was to investigate the effects of Spirulina on BV-2 microglial cell cytotoxicity and inflammatory genes expression. METHODS:BV-2 microglial cells were treated with lipopolysaccharide (LPS) (1 µg/ml) and various concentrations of Spirulina platensis water extract or its active component (C-phycocyanin...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1179/1476830512Y.0000000020

    authors: Chen JC,Liu KS,Yang TJ,Hwang JH,Chan YC,Lee IT

    更新日期:2012-11-01 00:00:00

  • Sulfur amino acid deficiency depresses brain glutathione concentration.

    abstract::Dietary sulfur amino acid content is a major determinant of glutathione concentration in some tissues. We examined whether brain glutathione (GSH), a key component of antioxidant defense important for minimizing ischemic injury, was also responsive to short-term sulfur amino acid deficiency. Female Long-Evans adult ra...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415x.2001.11747364

    authors: Paterson PG,Lyon AW,Kamencic H,Andersen LB,Juurlink BH

    更新日期:2001-01-01 00:00:00

  • Association between poor nutritional status and severe depression in Korean cerebral infarction patients.

    abstract:OBJECTIVE:The purpose of this study was to assess the association between cerebral infarction (CI), nutritional status, and depression. METHODS:Subjects with and without CI (n = 146; 73 CI vs. 73 non-CI) were recruited from Kyung Hee University Medical Center (Seoul, Korea) and were matched according to age and gende...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1179/1476830511Y.0000000023

    authors: Lim HJ,Choue R

    更新日期:2012-01-01 00:00:00

  • Perinatal supplementation with omega-3 fatty acids corrects the aberrant social and cognitive traits observed in a genetic model of autism based on FMR1 deletion in rats.

    abstract::Background and objective: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder for which no treatments exist. Fragile X syndrome (FXS) is the most common form of inherited mental retardation and the most frequent monogenic cause of ASD. Given the lack of pharmacological treatments for ASD, increasin...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2020.1819107

    authors: Schiavi S,Carbone E,Melancia F,Buzzelli V,Manduca A,Campolongo P,Pallottini V,Trezza V

    更新日期:2020-09-11 00:00:00

  • Naltrexone antagonism of morphine antinociception in sucrose- and chow-fed rats.

    abstract::Rats given long-term access to a palatable sucrose solution are more sensitive to (1) the analgesic potency of morphine and (2) the anorectic actions of naltrexone. In the present experiment, the ability of naltrexone to antagonize the antinociceptive properties of morphine was examined in sucrose- and chow-fed rats. ...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415042000198807

    authors: D'Anci KE,Kanarek RB

    更新日期:2004-02-01 00:00:00

  • Caffeine and energy drink use by combat arms soldiers in Afghanistan as a countermeasure for sleep loss and high operational demands.

    abstract:OBJECTIVES:Combat deployments are characterized by high operational demands with limited opportunities for sleep leading to fatigue and degraded cognitive and operational performance. Caffeine in moderate doses is recognized as an effective intervention for physical and cognitive decrements associated with sleep loss. ...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2018.1443996

    authors: McLellan TM,Riviere LA,Williams KW,McGurk D,Lieberman HR

    更新日期:2019-11-01 00:00:00

  • Iodine Deficiency and the Brain.

    abstract::The effects of iodine deficiency on growth and development are known as the iodine deficiency disorders (IDDs). Most common is goitre at all ages, but most significant are the effects on brain development during pregnancy. The major effect of iodine deficiency is the clinical syndrome of endemic cretinism characterise...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.1999.11747292

    authors: Hetzel BS

    更新日期:1999-01-01 00:00:00

  • Evaluation of the antidepressant- and anxiolytic-like effects of a hydrophilic extract from the green seaweed Ulva sp. in rats.

    abstract:OBJECTIVES:The green seaweed Ulva sp. contains a large amount of ulvans, a family of sulphated polysaccharides. The present study was designed to investigate in rats the antidepressant- and anxiolytic-like effects of a hydrophilic extract of Ulva sp. (MSP) containing about 45% of ulvans. METHODS:After a 14-day adminis...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2016.1276704

    authors: Violle N,Rozan P,Demais H,Nyvall Collen P,Bisson JF

    更新日期:2018-05-01 00:00:00

  • Advantageous effect of theanine intake on cognition.

    abstract::Theanine, γ-glutamylethylamide, is one of the major amino acid components in green tea. On the basis of the preventive effect of theanine intake after weaning on stress-induced impairment of recognition memory, the advantageous effect of theanine intake on recognition memory was examined in young rats, which were fed ...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1179/1476830513Y.0000000094

    authors: Tamano H,Fukura K,Suzuki M,Sakamoto K,Yokogoshi H,Takeda A

    更新日期:2014-11-01 00:00:00

  • Lifestyle factors, diet and attention-deficit/hyperactivity disorder in Spanish children - an observational study.

    abstract::Background: The aetiology of Attention Deficit Hyperactivity Disorder (ADHD) continues to be debated, although several contributing factors have been acknowledged. Objective: Assess the association between weight, birth attributes, exercise and sleep habits, dietary intake and adherence to a Mediterranean diet, and im...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2019.1660486

    authors: San Mauro Martin I,Sanz Rojo S,Garicano Vilar E,González Cosano L,Conty de la Campa R,Blumenfeld Olivares JA

    更新日期:2019-09-03 00:00:00

  • Feeding patterns and meal microstructure during development of a taste aversion to a threonine devoid diet.

    abstract::Food intake decreases and a conditioned taste aversion is induced when rats are fed a diet that is devoid of an indispensable amino acid. The purpose of this study was to characterize the meal patterns associated with (1) the onset of anorexia after the initial recognition of a threonine deficiency and (2) after the d...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/10284150290032003

    authors: Feurté S,Tomé D,Gietzen DW,Even PC,Nicolaïdis S,Fromentin G

    更新日期:2002-09-01 00:00:00

  • Diabetes modulates ethanol-induced increase in serotonin release from rat hippocampus: an in vivo microdialysis study.

    abstract::We examined whether diabetes mellitus (DM) affects the acute ethanol (EtOH)-induced increase in serotonin (5-HT) release from the rat hippocampus, and compared the findings with those obtained from non-DM rats. Hippocampal 5-HT was measured by using in vivo microdialysis. Rats were rendered diabetic by an injection of...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1179/1476830511Y.0000000006

    authors: Nagata T,Nishiyama A,Yamato T,Obata T,Aomine M

    更新日期:2011-05-01 00:00:00