Dietary choline during periadolescence attenuates cognitive damage caused by neonatal maternal separation in male rats.

Abstract:

OBJECTIVES:Choline (Ch) is an essential nutrient that acts as a cognitive facilitator when administered during perinatal periods, and it has been recognised as a 'pharmacological' agent that can ease cognitive dysfunctions provoked by exposure to damaging stimuli during early developmental stages. The aim of the present work is to determine whether providing a diet rich in Ch would reduce the severity of the memory deficit provoked by a neonatal stress episode in male adult rats. METHODS:The effect of Ch on memory was measured using memory tasks such as object and place recognition. Ontogenetic manipulations were conducted during two sensitive developmental periods. During the first post-natal (PN) 14 days, only the male rat pups were selected and half of them were separated from the mother, group maternal separation (MS). Subsequently, during periadolescence (PN 21-60), the rats were exposed to a deficient (DEF = 0 g/kg Ch chloride), sufficient (CON = 1.1 g/kg Ch chloride), or supplemented (SUP = 5 g/kg Ch chloride) diets for this nutrient. RESULTS:The results indicated that for group MS, only rats fed with the SUP diet were able to recognise the familiar object and place that had been experienced 24 hours before, unlike groups DEF and CON. In addition, whereas rats in the non-separated group (No-MS) recognised the object independently of the diet, only rats that received a DEF diet failed to recognise the place, showing that a Ch deficit affects spatial memory tasks. DISCUSSION:These results show that Ch supplementation during periadolescence can attenuate the memory deficit provoked by extended neonatal stress.

journal_name

Nutr Neurosci

journal_title

Nutritional neuroscience

authors

Moreno Gudiño H,Carías Picón D,de Brugada Sauras I

doi

10.1080/1028415X.2015.1126444

subject

Has Abstract

pub_date

2017-07-01 00:00:00

pages

327-335

issue

6

eissn

1028-415X

issn

1476-8305

journal_volume

20

pub_type

杂志文章
  • Lactobacillus helveticus-fermented milk improves learning and memory in mice.

    abstract:OBJECTIVES:To investigate the effects of Calpis sour milk whey, a Lactobacillus helveticus-fermented milk product, on learning and memory. METHODS:We evaluated improvement in scopolamine-induced memory impairment using the spontaneous alternation behaviour test, a measure of short-term memory. We also evaluated learni...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1179/1476830514Y.0000000122

    authors: Ohsawa K,Uchida N,Ohki K,Nakamura Y,Yokogoshi H

    更新日期:2015-07-01 00:00:00

  • Central L-ornithine, but not polyamines, induces a hypnotic effect in neonatal chicks under acute stress.

    abstract::To clarify whether L-ornithine and/or its metabolite involves sedative and hypnotic effects under social separation stress, the effects of intracerebroventricular (i.c.v.) injection of L-ornithine and polyamines (putrescine, spermidine and spermine) were compared in chicks. Birds were injected i.c.v. with 0.5 mumol of...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1179/147683010X12611460763481

    authors: Kurauchi I,Shigemi K,Kabuki Y,Hamasu K,Yamane H,Aoki M,Kawada Y,Morishita K,Denbow DM,Furuse M

    更新日期:2010-02-01 00:00:00

  • Perinatal supplementation with omega-3 fatty acids corrects the aberrant social and cognitive traits observed in a genetic model of autism based on FMR1 deletion in rats.

    abstract::Background and objective: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder for which no treatments exist. Fragile X syndrome (FXS) is the most common form of inherited mental retardation and the most frequent monogenic cause of ASD. Given the lack of pharmacological treatments for ASD, increasin...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2020.1819107

    authors: Schiavi S,Carbone E,Melancia F,Buzzelli V,Manduca A,Campolongo P,Pallottini V,Trezza V

    更新日期:2020-09-11 00:00:00

  • The effects of probiotics on mental health and hypothalamic-pituitary-adrenal axis: A randomized, double-blind, placebo-controlled trial in petrochemical workers.

    abstract:OBJECTIVE:The aim of this study was to determine effects of probiotic yogurt and multispecies probiotic capsule supplementation on mental health and hypothalamic-pituitary-adrenal axis in petrochemical workers. METHODS:The present randomized double-blind, placebo-controlled trial was conducted on 70 petrochemical work...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章,随机对照试验

    doi:10.1179/1476830515Y.0000000023

    authors: Mohammadi AA,Jazayeri S,Khosravi-Darani K,Solati Z,Mohammadpour N,Asemi Z,Adab Z,Djalali M,Tehrani-Doost M,Hosseini M,Eghtesadi S

    更新日期:2016-11-01 00:00:00

  • Mild experimental ketosis increases brain uptake of 11C-acetoacetate and 18F-fluorodeoxyglucose: a dual-tracer PET imaging study in rats.

    abstract::Brain glucose and ketone uptake was investigated in Fisher rats subjected to mild experimental ketonemia induced by a ketogenic diet (KD) or by 48 hours fasting (F). Two tracers were used, (11)C-acetoacetate ((11)C-AcAc) for ketones and (18)F-fluorodeoxyglucose for glucose, in a dual-tracer format for each animal. Thu...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1179/1476830510Y.0000000001

    authors: Pifferi F,Tremblay S,Croteau E,Fortier M,Tremblay-Mercier J,Lecomte R,Cunnane SC

    更新日期:2011-03-01 00:00:00

  • Protective role of curcumin against sulfite-induced structural changes in rats' medial prefrontal cortex.

    abstract:OBJECTIVES:Sodium metabisulfite as a food preservative can affect the central nervous system. Curcumin, the main ingredient of turmeric has neuroprotective activity. This study was designed to evaluate the effects of sulfite and curcumin on the medial prefrontal cortex (mPFC) using stereological methods. METHODS:Thirt...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1179/1476830514Y.0000000123

    authors: Noorafshan A,Asadi-Golshan R,Abdollahifar MA,Karbalay-Doust S

    更新日期:2015-08-01 00:00:00

  • Dietary patterns in relation with psychosomatic complaints profile: Results from SEPAHAN study among a large sample of general adults.

    abstract::Objective: Although dietary patterns have been evaluated in relation to psychological disorders, their associations with psychosomatic complaints are unclear. We investigated relations of dietary patterns with psychosomatic complaints profiles.Methods: In this cross-sectional study, a total of 3363 adults were include...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2018.1485611

    authors: Haghighatdoost F,Feizi A,Esmaillzadeh A,Hassanzadeh Keshteli A,Roohafza H,Afshar H,Adibi P

    更新日期:2020-03-01 00:00:00

  • The effects of dietary sulfur amino acid deficiency on rat brain glutathione concentration and neural damage in global hemispheric hypoxia-ischemia.

    abstract::Primary brain injury in stroke is followed by an excitotoxic cascade, oxidative stress and further neural damage. Glutathione is critical and depleted in oxidative stress. Since cysteine is limiting in glutathione synthesis, this study investigated the effect of dietary sulfur amino acid (SAA) deficiency on neural dam...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415021000055952

    authors: Bobyn PJ,Franklin JL,Wall CM,Thornhill JA,Juurlink BH,Paterson PG

    更新日期:2002-12-01 00:00:00

  • Understanding the role of nutrition in the brain and behavioral development of toddlers and preschool children: identifying and addressing methodological barriers.

    abstract::The preschool years (i.e. 1-5 years of age) is a time of rapid and dramatic postnatal brain development (i.e. neural plasticity), and of fundamental acquisition of cognitive development (i.e. working memory, attention and inhibitory control). Also, it is a time of transition from a direct maternal mediation/selection ...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章,评审

    doi:10.1179/147683009X423454

    authors: Rosales FJ,Reznick JS,Zeisel SH

    更新日期:2009-10-01 00:00:00

  • Depletion of dietary phytoestrogens reduces hippocampal plasticity and contextual fear memory stability in adult male mouse.

    abstract::Introduction: Phytoestrogens are non-steroidal estrogen analogues and are found primarily in soy products. They have received increasing attention as dietary supplements for estrogen deficiency and as modulators of endogenous estrogen functions, including cognition and emotion. In addition to modifying the levels of c...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2019.1698826

    authors: Çalışkan G,Raza SA,Demiray YE,Kul E,Sandhu KV,Stork O

    更新日期:2019-12-09 00:00:00

  • Association between poor nutritional status and severe depression in Korean cerebral infarction patients.

    abstract:OBJECTIVE:The purpose of this study was to assess the association between cerebral infarction (CI), nutritional status, and depression. METHODS:Subjects with and without CI (n = 146; 73 CI vs. 73 non-CI) were recruited from Kyung Hee University Medical Center (Seoul, Korea) and were matched according to age and gende...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1179/1476830511Y.0000000023

    authors: Lim HJ,Choue R

    更新日期:2012-01-01 00:00:00

  • Analysis of electrocorticographic patterns in rats fed standard or hyperlipidic diets in a normal state or during status epilepticus.

    abstract:OBJECTIVE:The consumption of hyperlipidic diets has grown markedly in recent decades, and several studies have linked this consumption with the development of neurodegenerative diseases. Conversely, hyperlipidic diets have been used as an alternative therapy for refractory epilepsy. The purpose of this study was to eva...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1179/1476830515Y.0000000033

    authors: Pessoa D,Cruz R,Machado B,Tenorio B,Nogueira R

    更新日期:2016-06-01 00:00:00

  • Differential Effects of Prenatal Protein Malnutrition and Prenatal Cocaine on Radial Arm Maze Performance in Adult Male Rats.

    abstract::The effects of prenatal cocaine and protein malnutrition were examined on acquisition of the radial arm maze in adult male Sprague-Dawley rats whose mothers were provided with a 6% casein, a 25% casein or a standard chow diet and cocaine (30mg/kg) or saline injections beginning 5 weeks prior to mating and continuing t...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.1999.11747269

    authors: Shumsky JS,Shultz PL,Galler JR,Tonkiss J

    更新日期:1999-01-01 00:00:00

  • Improved cognitive-cerebral function in older adults with chromium supplementation.

    abstract::Insulin resistance is implicated in the pathophysiological changes associated with Alzheimer's disease, and pharmaceutical treatments that overcome insulin resistance improve memory function in subjects with mild cognitive impairment (MCI) and early Alzheimer's disease. Chromium (Cr) supplementation improves glucose d...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章,随机对照试验

    doi:10.1179/147683010X12611460764084

    authors: Krikorian R,Eliassen JC,Boespflug EL,Nash TA,Shidler MD

    更新日期:2010-06-01 00:00:00

  • Low dietary protein is associated with an increase in food intake and a decrease in the in vitro release of radiolabeled glutamate and GABA from the lateral hypothalamus.

    abstract::Moderately low-protein diets lead to a rapid increase in food intake and body fat. The increase in feeding is associated with a decrease in the concentration of serum urea nitrogen, suggesting that the low-protein-induced increase in food intake may be related to the decreased metabolism of nitrogen from amino acids. ...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/10284150310001640365

    authors: White BD,Du F,Higginbotham DA

    更新日期:2003-12-01 00:00:00

  • Brain activity and connectivity changes in response to nutritive natural sugars, non-nutritive natural sugar replacements and artificial sweeteners.

    abstract::Introduction: The brain plays an important regulatory role in directing energy homeostasis and eating behavior. The increased ingestion of sugars and sweeteners over the last decades makes investigating the effects of these substances on the regulatory function of the brain of particular interest. We investigated whol...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2019.1639306

    authors: Van Opstal AM,Hafkemeijer A,van den Berg-Huysmans AA,Hoeksma M,Mulder TPJ,Pijl H,Rombouts SARB,van der Grond J

    更新日期:2019-07-10 00:00:00

  • Evaluation of the antidepressant- and anxiolytic-like effects of a hydrophilic extract from the green seaweed Ulva sp. in rats.

    abstract:OBJECTIVES:The green seaweed Ulva sp. contains a large amount of ulvans, a family of sulphated polysaccharides. The present study was designed to investigate in rats the antidepressant- and anxiolytic-like effects of a hydrophilic extract of Ulva sp. (MSP) containing about 45% of ulvans. METHODS:After a 14-day adminis...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2016.1276704

    authors: Violle N,Rozan P,Demais H,Nyvall Collen P,Bisson JF

    更新日期:2018-05-01 00:00:00

  • The natural xanthone alpha-mangostin reduces oxidative damage in rat brain tissue.

    abstract::The antiperoxidative properties of alpha-mangostin, a xanthone isolated from mangosteen fruit, were tested for the first time in nerve tissue exposed to different toxic insults. Two reliable biological preparations (rat brain homogenates and synaptosomal P2 fractions) were exposed to the toxic actions of a free radica...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1179/147683009X388850

    authors: Márquez-Valadez B,Lugo-Huitrón R,Valdivia-Cerda V,Miranda-Ramírez LR,Pérez-De La Cruz V,González-Cuahutencos O,Rivero-Cruz I,Mata R,Santamaría A,Pedraza-Chaverrí J

    更新日期:2009-02-01 00:00:00

  • Nutrition status survey of type 2 and 3 spinal muscular atrophy in Chinese population.

    abstract:OBJECTIVE:To evaluate the nutritional status of children with SMA types II and III in a Chinese population. METHODS:We performed a retrospective medical record review of prospectively collected data from children with SMA types II and III in a single centre. We analysed data including clinical parameters, anthropometr...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2020.1871212

    authors: Zhou Y,Chen J,Gong X,Lu Z,Hua H,Zhu X,Shi P,Li X,Zhou S,Wang Y,Qian T

    更新日期:2021-01-23 00:00:00

  • Response to Energy Dilution in the Short Term: Evidence of Nutritional Wisdom in Young Children?

    abstract::Young children respond to energy dilution achieved using fat or sugar substitutes by compensating for reduced energy within a single meal. The ability to respond to energy dilution in the short term may diminish with age, since adults do not reliably demonstrate accurate caloric compensation in the short term. Two exp...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2000.11747329

    authors: Hetherington MM,Wood C,Lyburn SC

    更新日期:2000-01-01 00:00:00

  • Green tea and vitamin C ameliorate some neuro-functional and biochemical signs of arsenic toxicity in rats.

    abstract:BACKGROUND/OBJECTIVES:Nervous system damage is one of the consequences of oral exposure to waterborne inorganic arsenic. In this work, the role of oxidative status in the neurotoxicity of arsenic and the possible role of two foodborne antioxidants in ameliorating arsenic-related oxidative stress were investigated. MET...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1179/1476830514Y.0000000151

    authors: Sárközi K,Papp A,Horváth E,Máté Z,Ferencz Á,Hermesz E,Krisch J,Paulik E,Szabó A

    更新日期:2016-01-01 00:00:00

  • Lactation in large litters influences anxiety, memory, and spreading depression in adult male rats that were chronically subjected to a non-convulsive pilocarpine dose.

    abstract::Objectives: Unfavorable lactation influences brain excitability and behavioral reactions in adults. Administration early in life of the cholinergic agonist, pilocarpine, even at non-convulsive doses, alters the brain excitability-related phenomenon known as cortical spreading depression (CSD), and produce anxiogenic-l...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2020.1819103

    authors: Benevides RDL,de-Lima SMV,Chagas CL,de Lima CF,Abadie-Guedes R,Guedes RCA

    更新日期:2020-09-11 00:00:00

  • Vitamin D metabolites, D3 and D2, and their independent associations with depression symptoms among adults in the United States.

    abstract::Background: The two metabolites of vitamin D; serum 25-hydroxyvitamin D3 (25(OH)D3) and D2 (25(OH)D2), and their independent roles in mood regulation are unexplored. This study aims to examine 25(OH)D3 and 25(OH)D2 and their interplay with depression symptoms. Materials and Methods: Utilizing data from the U.S. Nation...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2020.1794422

    authors: Bigman G

    更新日期:2020-07-20 00:00:00

  • Sulfur amino acid deficiency depresses brain glutathione concentration.

    abstract::Dietary sulfur amino acid content is a major determinant of glutathione concentration in some tissues. We examined whether brain glutathione (GSH), a key component of antioxidant defense important for minimizing ischemic injury, was also responsive to short-term sulfur amino acid deficiency. Female Long-Evans adult ra...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415x.2001.11747364

    authors: Paterson PG,Lyon AW,Kamencic H,Andersen LB,Juurlink BH

    更新日期:2001-01-01 00:00:00

  • Holothuria scabra extracts exhibit anti-Parkinson potential in C. elegans: A model for anti-Parkinson testing.

    abstract:OBJECTIVES:Parkinson's disease (PD) is associated with aggregation of α-synuclein and selective death of dopaminergic (DA) neurons in the substantia nigra, thereby leading to cognitive and motor impairments. Nowadays, the drugs commonly used for PD treatment, such as levodopa, provide only symptomatic relief. Therefore...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2017.1299437

    authors: Chalorak P,Jattujan P,Nobsathian S,Poomtong T,Sobhon P,Meemon K

    更新日期:2018-07-01 00:00:00

  • Inhibitory effect of apelin-12 on nocturnal food intake in the rat.

    abstract::Apelin, the endogenous peptide ligand of the APJ receptor, is expressed in brain regions implicated in food and water intake. This study reports for the first time, the effect of apelin-12, one of the most potent apelin peptides, on spontaneous (nocturnal) feeding. Randomised intracerebroventricular injection of 1, 3 ...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415031000111273

    authors: O'Shea M,Hansen MJ,Tatemoto K,Morris MJ

    更新日期:2003-06-01 00:00:00

  • Changes of growth hormone-releasing hormone and somatostatin neurons in the rat hypothalamus induced by genistein: a stereological study.

    abstract:OBJECTIVES:Genistein is a plant-derived estrogenic isoflavone commonly found in dietary and therapeutic supplements, due to its potential health benefits. Growth hormone-releasing hormone (GHRH) and somatostatin (SS) are neurosecretory peptides synthesized in neurons of the hypothalamus and regulate the growth hormone ...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1179/1476830514Y.0000000143

    authors: Trifunović S,Manojlović-Stojanoski M,Ristić N,Nestorović N,Medigović I,Živanović J,Milošević V

    更新日期:2016-12-01 00:00:00

  • Volume of the Sexually Dimorphic Nucleus of the Preoptic Area in Rats Exposed to a Maternal High Fat Diet.

    abstract::Mice and rats exposed to a maternal diet high in fat have an increased risk of reproductive system tumors later in life. To test whether a part of the hypothalamus associated with sex differentiation, the sexually dimorphic nucleus of the preoptic area (SDN-POA), might be involved, this nucleus was measured in the off...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.1999.11747258

    authors: Walker BE

    更新日期:1999-01-01 00:00:00

  • Malnutrition and REM-sleep deprivation modulate in rats the impairment of spreading depression by a single sub-convulsing dose of pilocarpine.

    abstract::This study aimed to investigate the effect of a single injection of pilocarpine upon the phenomenon of cortical spreading depression (SD), in adult rats submitted to early malnutrition and/or to REM-sleep deprivation for 72h prior to the SD-recordings. The SD was recorded continuously for 3-4h in 13 well-nourished (W)...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/10284150412331281031

    authors: De Vasconcelos CA,De Oliveira JA,De Oliveira Costat LA,Guedes RC

    更新日期:2004-06-01 00:00:00

  • Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis.

    abstract::Objective: The association between vitamin E supplementation and Alzheimer's disease (AD) was controversial because of conflicting data in the literature. This study was designed to systematically evaluate evidence about the efficacy of vitamin E supplementation not only on the risk but also on the progression of AD. ...

    journal_title:Nutritional neuroscience

    pub_type: 杂志文章

    doi:10.1080/1028415X.2019.1585506

    authors: Wang W,Li J,Zhang H,Wang X,Zhang X

    更新日期:2021-01-01 00:00:00