Abstract:
:To clarify whether L-ornithine and/or its metabolite involves sedative and hypnotic effects under social separation stress, the effects of intracerebroventricular (i.c.v.) injection of L-ornithine and polyamines (putrescine, spermidine and spermine) were compared in chicks. Birds were injected i.c.v. with 0.5 mumol of L-ornithine, putrescine, spermidine, spermine or saline (control). After injection, chicks were immediately separated from the flock and monitored for the number of distress vocalizations and various postures. L-Ornithine greatly attenuated the stress response and caused sedative and hypnotic effects. Among the polyamines, only putrescine attenuated distress vocalizations but did not induce sleep. In conclusion, the sedative and hypnotic effect of L-ornithine was mainly induced by L-ornithine itself, while the polyamines contributed to the sedative, but not hypnotic, effect under social separation stress.
journal_name
Nutr Neuroscijournal_title
Nutritional neuroscienceauthors
Kurauchi I,Shigemi K,Kabuki Y,Hamasu K,Yamane H,Aoki M,Kawada Y,Morishita K,Denbow DM,Furuse Mdoi
10.1179/147683010X12611460763481subject
Has Abstractpub_date
2010-02-01 00:00:00pages
17-20issue
1eissn
1028-415Xissn
1476-8305journal_volume
13pub_type
杂志文章abstract::While there are many theories on the control of feeding behavior that emphasize a role for energy substrates and their metabolism, the mechanism that couples changes in energy substrate supply and metabolism to alterations in food intake remains unclear. The purpose of the present project was to investigate the possib...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.1999.11747274
更新日期:1999-01-01 00:00:00
abstract::Objective: The aim of the current study was to examine the unique and joint contributions of iron deficiency, iron supplementation, and psychosocial stress in infancy and stress in adolescence to neurocognitive functioning in adolescence. Methods: The current study (N = 796; Mage = 14.4y) involved a prospective cohort...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2019.1651105
更新日期:2019-08-09 00:00:00
abstract::Organophosphorus compounds are widely used in agriculture. Epidemiological studies propose that pesticide exposure is a risk factor for Alzheimer's disease (AD), but the mechanisms are unclear. Here, we investigated the impact of malathion exposure on the cognitive ability and the underlying mechanisms in rats. Moreov...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2018.1492772
更新日期:2020-03-01 00:00:00
abstract::We compared the maturation of the monosynaptic stretch reflex in control rats and in rats submitted to neonatal malnutrition. Electrical stimulations of the sciatic nerve were applied in wakeful rats of different ages (21-90 days) to record, by surface electrodes, the maximal direct motor response (M(max)) or the maxi...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1179/147683008X344138
更新日期:2008-10-01 00:00:00
abstract::The effects of prenatal cocaine and protein malnutrition were examined on acquisition of the radial arm maze in adult male Sprague-Dawley rats whose mothers were provided with a 6% casein, a 25% casein or a standard chow diet and cocaine (30mg/kg) or saline injections beginning 5 weeks prior to mating and continuing t...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.1999.11747269
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVES:Ethanol consumption induces neurological disorders including cognitive dysfunction. Oxidative damage is considered a likely cause of cognitive deficits. We aimed to investigate the effects of rosmarinic acid (RA) in different doses for 30 days on chronic ethanol-induced cognitive dysfunction using the passiv...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2016.1203125
更新日期:2017-11-01 00:00:00
abstract::A high-fat diet (HFD) during pregnancy influences the neurodevelopment of progeny, particularly in the hippocampus, a brain region involved in cognitive processes. The hippocampus has high levels of leptin receptors (Ob-R) that participate in synaptic plasticity. This study examined the effect of maternal HFD during g...
journal_title:Nutritional neuroscience
pub_type: 信件
doi:10.1080/1028415X.2020.1728473
更新日期:2020-02-19 00:00:00
abstract:OBJECTIVES:The green seaweed Ulva sp. contains a large amount of ulvans, a family of sulphated polysaccharides. The present study was designed to investigate in rats the antidepressant- and anxiolytic-like effects of a hydrophilic extract of Ulva sp. (MSP) containing about 45% of ulvans. METHODS:After a 14-day adminis...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2016.1276704
更新日期:2018-05-01 00:00:00
abstract::Objectives: This study was designed to investigate the vitamin A (VA) and vitamin D (VD) levels in children with autism spectrum disorders (ASD) and to determine whether co-deficiency of VA and VD exacerbates clinical symptoms in autistic children. Methods: The Autism Behavior Checklist, Childhood Autism Rating Scale ...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2017.1423268
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine effects of probiotic yogurt and multispecies probiotic capsule supplementation on mental health and hypothalamic-pituitary-adrenal axis in petrochemical workers. METHODS:The present randomized double-blind, placebo-controlled trial was conducted on 70 petrochemical work...
journal_title:Nutritional neuroscience
pub_type: 杂志文章,随机对照试验
doi:10.1179/1476830515Y.0000000023
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:Our aim was to investigate the effects of Spirulina on BV-2 microglial cell cytotoxicity and inflammatory genes expression. METHODS:BV-2 microglial cells were treated with lipopolysaccharide (LPS) (1 µg/ml) and various concentrations of Spirulina platensis water extract or its active component (C-phycocyanin...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1179/1476830512Y.0000000020
更新日期:2012-11-01 00:00:00
abstract::Background: Essential fatty acids (EFAs) and non-essential fatty acids (nEFAs) exert experimental and clinical neuroprotection in neurodegenerative diseases. The main EFAs, eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), nEFAs, and oleic acid (OA) contained in olive and fish oils are inserted into the cell me...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2019.1584692
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVES:Western-style diets high in saturated fat and refined carbohydrate have been shown to alter gut microbiota as well as being associated with altered behaviour and learning ability. The objective of this study was to determine the effects of short-term intake of a Western-style diet on intestinal cytokine expr...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1179/1476830515Y.0000000034
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVES:Coenzyme Q10 (CoQ10, ubiquinone) stands among the safest supplements in the elderly to protect against cardiovascular disorders. Noteworthy, CoQ10 deficiency is common in many surviving stroke patients as they are mostly prescribed statins for the secondary prevention of stroke incidence lifelong. Accordingl...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2017.1376928
更新日期:2019-04-01 00:00:00
abstract:RATIONALE:Recent research suggests that chewing gum may increase alertness and lead to changes in cognitive performance. The present study examined effects of chewing gum on these functions within the context of a single study. OBJECTIVES:This study had four main aims. The first was to examine whether chewing gum impr...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1179/147683009X423247
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:To evaluate cognitive functions and behavioral changes in the patients with vitamin B12 deficiency neurological syndromes (VBDNS) using detailed clinical psychometric and P3 studies and their response to treatment. METHODS:The patients with VBDNS were included and their detailed medical history was recorded...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1179/1476830512Y.0000000028
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:A low antioxidants status has been shown to result in oxidative stress and cognitive impairment. Because antioxidants can protect the nervous system, it is expected that a better blood antioxidant status might be related to sustained attention. However, the relationship between the blood antioxidant status an...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1179/1476830515Y.0000000032
更新日期:2015-01-01 00:00:00
abstract::Depression is a major public health problem affecting about 12% of the world population. Drugs exist but they have many side effects. In the last few years, natural substances (e.g. flavonoids) have been tested to cure such disorders. Cocoa polyphenolic extract is a complex compound prepared from non-roasted cocoa bea...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1179/147683008X344165
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVES:Genistein is a plant-derived estrogenic isoflavone commonly found in dietary and therapeutic supplements, due to its potential health benefits. Growth hormone-releasing hormone (GHRH) and somatostatin (SS) are neurosecretory peptides synthesized in neurons of the hypothalamus and regulate the growth hormone ...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1179/1476830514Y.0000000143
更新日期:2016-12-01 00:00:00
abstract::Objective: The association between vitamin E supplementation and Alzheimer's disease (AD) was controversial because of conflicting data in the literature. This study was designed to systematically evaluate evidence about the efficacy of vitamin E supplementation not only on the risk but also on the progression of AD. ...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2019.1585506
更新日期:2021-01-01 00:00:00
abstract::Objectives: Ghrelin acts on a variety of central- and peripheral organs causing an orexigenic effect, conclusively followed by increased caloric intake. Recent studies have indicated that ghrelin's function as an orexigenic agent does not entirely reflect the full functional properties of the peptide. Specifically, gh...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2020.1863740
更新日期:2020-12-29 00:00:00
abstract::Background: This study aimed to analyse the impact of des-acyl and acyl ghrelin (AG) on a wide range of muscular and metabolic markers and in order to discover the possible relationships and interactions of des-acylated ghrelin (DAG) on eating disorders.Materials & Methods: A total of 88 subjects (64 women and 24 men,...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2020.1752997
更新日期:2020-04-15 00:00:00
abstract:BACKGROUND:Differences in the composition of control diets may confound outcomes in studies investigating dietary effects. OBJECTIVE:We compared the effects of two control diets commonly used in mice studies, chow (SD) and a purified low-fat diet (LFD), in relation to a chronic high-fat diet (HFD). We hypothesized tha...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2017.1349359
更新日期:2019-01-01 00:00:00
abstract::This study examined effects of a single protein-free (PROT-free), high carbohydrate meal (0% protein, 82% carbohydrate) or control meal (20% protein, 62% carbohydrate) on coping behavior and neurotransmitter levels of male Fischer 344 rats. Meals varying in protein/carbohydrate ratio differentially affect transport of...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/10284150400017330
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to determine the influence of dietary macronutrient composition on central NPY's orexigenic effect in chicks. METHODS:Day-of-hatch chicks were fed one of three diets (3000 kcal ME/kg) ad libitum from hatch: high carbohydrate (HC), high fat (HF; 30% ME derived from soybean oil)...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2017.1296606
更新日期:2018-07-01 00:00:00
abstract::Background: Adherence to a Mediterranean diet is associated with higher cognitive function and reduced risk of dementia in Mediterranean populations. However, few studies have investigated the association between Mediterranean diet adherence and cognition in populations outside of the Mediterranean basin. Furthermore,...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2019.1655201
更新日期:2019-08-21 00:00:00
abstract:OBJECTIVES:Choline (Ch) is an essential nutrient that acts as a cognitive facilitator when administered during perinatal periods, and it has been recognised as a 'pharmacological' agent that can ease cognitive dysfunctions provoked by exposure to damaging stimuli during early developmental stages. The aim of the presen...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2015.1126444
更新日期:2017-07-01 00:00:00
abstract::Young children respond to energy dilution achieved using fat or sugar substitutes by compensating for reduced energy within a single meal. The ability to respond to energy dilution in the short term may diminish with age, since adults do not reliably demonstrate accurate caloric compensation in the short term. Two exp...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2000.11747329
更新日期:2000-01-01 00:00:00
abstract::We examined whether diabetes mellitus (DM) affects the acute ethanol (EtOH)-induced increase in serotonin (5-HT) release from the rat hippocampus, and compared the findings with those obtained from non-DM rats. Hippocampal 5-HT was measured by using in vivo microdialysis. Rats were rendered diabetic by an injection of...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1179/1476830511Y.0000000006
更新日期:2011-05-01 00:00:00
abstract::Adult female rats, receiving a low protein diet at perinatal age and then recovered with balanced chow (D rats), were evaluated in the Open Field Drink Test (OFDT), after different acute and chronic treatments with benzodiazepines (BZD) ligands, as compared with control (C) female rats. Control and D rats showed simil...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.1998.11747253
更新日期:1998-01-01 00:00:00