Preparation of poly(epsilon-caprolactone)/continuous bioglass fibre composite using monomer transfer moulding for bone implant.

Abstract:

:Poly(epsilon-caprolactone) (PCL)/continuous bioglass fibre composite was prepared using the monomer transfer moulding technique coupled with a surface initiated polymerisation. The bioglass fibres were surface treated with an amine ended silane in order to initiate polymerisation of epsilon-caprolactone from the fibre surface. Surface initiated polymerisation significantly improved the Young's modulus and flexural strength and water resistance of the composite. Initial in vitro biocompatibility assessment suggests that amine ended silane treatment of bioglass fibres before their inclusion in the composite does not have a negative effect on the biological responses in terms of macrophage activation as measured by IL-1beta release and craniofacial osteoblast attachment.

journal_name

Biomaterials

journal_title

Biomaterials

authors

Jiang G,Evans ME,Jones IA,Rudd CD,Scotchford CA,Walker GS

doi

10.1016/j.biomaterials.2004.07.042

keywords:

subject

Has Abstract

pub_date

2005-05-01 00:00:00

pages

2281-8

issue

15

eissn

0142-9612

issn

1878-5905

pii

S0142-9612(04)00695-7

journal_volume

26

pub_type

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