Abstract:
:Membranes of 75% and 100% benzyl hyaluronate esters (percentage of total carboxylate groups esterified) were prepared and their water vapour, oxygen and carbon dioxide transmission rates determined. The values of these properties were compared with the values obtained for several commercial wound dressings under the same conditions. The benzyl hyaluronate membranes showed water vapour transmission rates (2157-2327 gm-2 per day) comparable to those from commercial skin dressings (426-2047 gm-2 per day). In the dry state, the benzyl hyaluronate membranes showed lower oxygen and carbon dioxide transmission rates. Taking into account the biocompatibility of the hyaluronic acid esters, and the possibility that therapeutic agents could be incorporated into these membranes, the results indicate that the benzyl hyaluronate membranes have potential wound dressing applications.
journal_name
Biomaterialsjournal_title
Biomaterialsauthors
Ruiz-Cardona L,Sanzgiri YD,Benedetti LM,Stella VJ,Topp EMdoi
10.1016/0142-9612(95)00324-xsubject
Has Abstractpub_date
1996-08-01 00:00:00pages
1639-43issue
16eissn
0142-9612issn
1878-5905pii
014296129500324Xjournal_volume
17pub_type
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