Calcium phosphate coating of nickel-titanium shape-memory alloys. Coating procedure and adherence of leukocytes and platelets.

Abstract:

:Nickel-titanium shape-memory alloys (NiTi-SMA) were coated with calcium phosphate by dipping in oversaturated calcium phosphate solution. The layer thickness (typically 5-20 micrometer) can be varied by choice of the immersion time. The porous nature of the layer of microcrystals makes it mechanically stable enough to withstand both the shape-memory transition upon cooling and heating and also strong bending of the material (superelastic effect). This layer may improve the biocompatibility of NiTi-SMA, particulary for osteosynthetic devices by creating a more physiological surface and by restricting a potential nickel release. The adherence of human leukocytes (peripheral blood mononuclear cells and polymorphonuclear neutrophil granulocytes) and platelets to the calcium phosphate layer was analyzed in vitro. In comparison to non-coated NiTi-SMA, leukocytes and platelets showed a significantly increased adhesion to the coated NiTi-SMA.

journal_name

Biomaterials

journal_title

Biomaterials

authors

Choi J,Bogdanski D,Köller M,Esenwein SA,Müller D,Muhr G,Epple M

doi

10.1016/s0142-9612(03)00241-2

keywords:

subject

Has Abstract

pub_date

2003-09-01 00:00:00

pages

3689-96

issue

21

eissn

0142-9612

issn

1878-5905

pii

S0142961203002412

journal_volume

24

pub_type

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