The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles.

abstract：:A silicone-based prepolymer was used as the major component for the fabrication of novel ocular devices. Gentamicin sulphate was used as a probe drug, due to its high aqueous solubility and widespread application. Mechanical properties of films containing the drug before and after gamma sterilization and exposure to h...

journal_title：Biomaterials

authors： Bawa R,Nandu M

更新日期：1990-11-01 00:00:00

abstract：:Hydroxy-fluorapatites (OH-FAps) occur biologically in teeth and form the basis for application as biomaterials. This work aims to synthesize a series of fluoride substituted calcium hydroxyapatites (OHAps) to determine how fluoride influences the synthesis and the resulting characteristics of solid solutions. OH-FAPs ...

journal_title：Biomaterials

authors： Rodríguez-Lorenzo LM,Hart JN,Gross KA

更新日期：2003-09-01 00:00:00

abstract：:Cationic nanoparticles are a promising class of transfection agents for oligonucleotide and gene delivery, but vary greatly in their effectiveness and cytotoxicity. Recently, we developed a new class of cationic transfection agents based on cationic shell-crosslinked knedel-like nanoparticles (cSCKs) that efficiently ...

journal_title：Biomaterials

authors： Zhang K,Fang H,Wang Z,Li Z,Taylor JS,Wooley KL

更新日期：2010-03-01 00:00:00

abstract：:Semiconductor quantum dots and upconversion nanoparticles have been broadly used for live cell imaging due to their color tunability and photostability etc. However, these inorganic materials often contain heavy metals and potentially have metabolism problems. To overcome these issues, herein, we report a type of orga...

journal_title：Biomaterials

authors： Xu R,Huang L,Wei W,Chen X,Zhang X,Zhang X

更新日期：2016-07-01 00:00:00

abstract：:Three types of bioactive polymethylmethacrylate (PMMA)-based bone cement containing nano-sized titania (TiO2) particles were prepared, and their mechanical properties and osteoconductivity are evaluated. The three types of bioactive bone cement were T50c, ST50c, and ST60c, which contained 50 wt% TiO2, and 50 and 60 wt...

journal_title：Biomaterials

authors： Goto K,Tamura J,Shinzato S,Fujibayashi S,Hashimoto M,Kawashita M,Kokubo T,Nakamura T

更新日期：2005-11-01 00:00:00

abstract：:We hypothesized that reduced stem stiffness of orthopaedic implants contributes to a high risk of loosening, since interface stresses and relative motions may exceed a tolerable range. To study this hypothesis, three types of load-bearing implant with different stiffnesses were inserted into the tibia of the goat. His...

journal_title：Biomaterials

authors： Buma P,van Loon PJ,Versleyen H,Weinans H,Slooff TJ,de Groot K,Huiskes R

更新日期：1997-09-01 00:00:00

abstract：:The aim of this study was to evaluate the physical-chemical properties, in vivo biocompatibility and antimicrobial activity of bioactive glasses (BG) used as a controlled release device for tetracycline hydrochloride and an inclusion complex formed by tetracycline and beta-cyclodextrin at 1:1 molar ratio. The BG as we...

journal_title：Biomaterials

authors： Domingues ZR,Cortés ME,Gomes TA,Diniz HF,Freitas CS,Gomes JB,Faria AM,Sinisterra RD

更新日期：2004-01-01 00:00:00

abstract：:Novel biological adhesives made from chitin derivatives were prepared and evaluated for their adhesive properties and biocompatibility. Chitin derivatives with acrylic groups, such as 2-hydroxy-3-methacryloyloxypropylated carboxymethyl chitin (HMA-CM-chitin), were synthesized and cured by the addition of an aqueous hy...

journal_title：Biomaterials

authors： Azuma K,Nishihara M,Shimizu H,Itoh Y,Takashima O,Osaki T,Itoh N,Imagawa T,Murahata Y,Tsuka T,Izawa H,Ifuku S,Minami S,Saimoto H,Okamoto Y,Morimoto M

更新日期：2015-02-01 00:00:00

abstract：:Primary canine oral mucosal epithelial cells were cultured on temperature-responsive dishes and cell culture inserts to fabricate transplantable epithelial cell sheets. When 3T3 feeder layers and fetal bovine serum were eliminated from dish culture, the harvested cell sheets became significantly more fragile. In contr...

journal_title：Biomaterials

authors： Murakami D,Yamato M,Nishida K,Ohki T,Takagi R,Yang J,Namiki H,Okano T

更新日期：2006-11-01 00:00:00

abstract：:Retinal pigment epithelial (RPE) cellular morphology and function are vital to the health of the retina. In age-related macular degeneration, RPE dysfunction and changes in Bruch's membrane occur. Thus, a potential cure is a dual-layer biomimetic transplant consisting of a layer of healthy RPE cells cultured on a supp...

journal_title：Biomaterials

authors： Lee CJ,Fishman HA,Bent SF

更新日期：2007-04-01 00:00:00

abstract：:Procoagulant (activated) platelets provide a site for assembly of the prothrombinase complex which can rapidly convert prothrombin into thrombin (a potent inducer of clot formation). Previously, we reported that adhesion of platelets to surfaces preadsorbed with blood plasma caused them to become procoagulant. In the ...

journal_title：Biomaterials

authors： Grunkemeier JM,Tsai WB,McFarland CD,Horbett TA

更新日期：2000-11-01 00:00:00

abstract：:Mesoporous silica nanoshell (MSN) coating has been demonstrated as a versatile surface modification strategy for various kinds of inorganic functional nanoparticles, such as gold nanorods (GNRs), to achieve not only improved nanoparticle stability but also concomitant drug loading capability. However, limited drug loa...

journal_title：Biomaterials

authors： Xu C,Chen F,Valdovinos HF,Jiang D,Goel S,Yu B,Sun H,Barnhart TE,Moon JJ,Cai W

更新日期：2018-05-01 00:00:00

abstract：:A simple approach to the mechanical modulation of layer-by-layer (LbL) films is through manipulation of the film assembly. Here, we report results based on altering the salt concentration during film assembly and its effect on film rigidity. Based on changes in film rigidity, cell adhesion characteristics and transfec...

journal_title：Biomaterials

authors： Blacklock J,Vetter A,Lankenau A,Oupický D,Möhwald H

更新日期：2010-09-01 00:00:00

abstract：:Protein therapeutics targeting inflammatory mediators have shown great promise for the treatment of autoimmunities such as rheumatoid arthritis (RA). However, a significant challenge in this area has been their low in vivo stability and consequently their severely compromised therapeutic efficacy. One such therapeutic...

journal_title：Biomaterials

authors： Pasi S,Kant R,Gupta S,Surolia A

更新日期：2015-02-01 00:00:00

abstract：:Despite being increasingly used as artificial enzymes, little has been known for the origin of the pH-switchable peroxidase-like and catalase-like activities of metals. Using calculations and experiments, we report the mechanisms for both activities and their pH-switchability for metals Au, Ag, Pd and Pt. The calculat...

journal_title：Biomaterials

authors： Li J,Liu W,Wu X,Gao X

更新日期：2015-04-01 00:00:00

abstract：:Combinations of an alkali-containing calcium phosphate-like rhenanite, sodium whitlockite or calcium potassium phosphate and a chloride-containing calcium phosphate-like spodiosite or chloroapatite with or without additions of other calcium phosphates like monocalcium phosphate monohydrate, dicalcium phosphate or dica...

journal_title：Biomaterials

authors： Bermúdez O,Boltong MG,Driessens FC,Ginebra MP,Fernández E,Planell JA

更新日期：1994-10-01 00:00:00

abstract：:In the present study, the effects of implant design and surface properties on peri-implant bone response were evaluated with both conventional histomorphometry and micro-computed tomography (micro-CT), using two geometrically different dental implants (Screw type, St; Push-in, Pi) either or not surface-modified (non-c...

journal_title：Biomaterials

authors： Schouten C,Meijer GJ,van den Beucken JJ,Spauwen PH,Jansen JA

更新日期：2009-09-01 00:00:00

abstract：:The use of non-viral nanoparticulate systems for the delivery of therapeutic agents is receiving considerable attention for medical and pharmaceutical applications. This increasing interest results from the fact that these systems can be designed to meet specific physicochemical requirements, and they display low toxi...

journal_title：Biomaterials

authors： Chellat F,Merhi Y,Moreau A,Yahia L

更新日期：2005-12-01 00:00:00

abstract：:A new system of single piece electrodes was applied to in vivo and in vitro measurements of anodic polarization of several alloys used in orthopaedic implants. The tested surface was scrutinized with a stereomicroscope after each experiment. This confirmed pit formation and excluded the possibility of other sudden inc...

journal_title：Biomaterials

authors： Nakayama Y,Yamamuro T,Kotoura Y,Oka M

更新日期：1989-08-01 00:00:00

abstract：:The formation of a confluent endothelium on expanded polytetrafluoroethylene (PTFE) vascular prostheses has never been observed. This lack of endothelialization is known to be one of the main reasons leading to the development of thromboses and/or intimal hyperplasia. In this context, several efforts were put forward ...

journal_title：Biomaterials

authors： Crombez M,Chevallier P,-Gaudreault RC,Petitclerc E,Mantovani D,Laroche G

更新日期：2005-12-01 00:00:00

abstract：:A synthetic process for obtaining high-molecular-weight block copolymers containing poly(lactic-glycolic acid) and poly(ethylene glycol) segments has been established. This process involves the reaction of poly(ethylene glycols) with phosgene, followed by polycondensation of the resulting alpha, omega-bis(chloroformat...

journal_title：Biomaterials

authors： Ferruti P,Penco M,D'Addato P,Ranucci E,Deghenghi R

更新日期：1995-12-01 00:00:00

abstract：:Space experimentation of cardiomyocyte differentiation from human induced pluripotent stem cells offers an exciting opportunity to explore the potential of these cells for disease modeling, drug discovery and regenerative medicine. Previous studies on the International Space Station were done with 2D non-cryopreserved...

journal_title：Biomaterials

authors： Rampoldi A,Jha R,Fite J,Boland G,Xu C

更新日期：2021-01-11 00:00:00

abstract：:Decellularized native extracellular matrix (ECM) biomaterials are widely used in tissue engineering and have reached clinical application as biomesh implants. To enhance their regenerative properties and postimplantation performance, ECM biomaterials could be functionalized via immobilization of bioactive molecules. T...

journal_title：Biomaterials

authors： Ren X,Evangelista-Leite D,Wu T,Rajab TK,Moser PT,Kitano K,Economopoulos KP,Gorman DE,Bloom JP,Tan JJ,Gilpin SE,Zhou H,Mathisen DJ,Ott HC

更新日期：2018-11-01 00:00:00

abstract：:Topical therapy is the most favored form of treatment for whitening against hyperpigmentation and sunburn because it lends itself to self-administration, patient compliance, and absence of systemic adverse effects. However, transdermal delivery of hydrophilic chemicals is difficult. The main purpose of this study is t...

journal_title：Biomaterials

authors： Candan G,Michiue H,Ishikawa S,Fujimura A,Hayashi K,Uneda A,Mori A,Ohmori I,Nishiki T,Matsui H,Tomizawa K

更新日期：2012-09-01 00:00:00

abstract：:The ligand-tethered poly(ethylene oxide-propylene oxide-ethylene oxide) (PEO-PPO-PEO) triblock copolymer was explored to engineer poly(DL-lactic acid) (PDL-LA) material to promote cell attachment and growth. The PEO-PPO-PEO was activated by methyl sulfonyl chloride and the amino acid, and peptide were attached. By ble...

journal_title：Biomaterials

authors： Ji J,Zhu H,Shen J

更新日期：2004-05-01 00:00:00

abstract：:We present here an easy method to modify the surface chemistry of polymeric microcapsules of perfluorooctyl bromide used as ultrasound contrast agents (UCAs). Capsules were obtained by a solvent emulsification-evaporation process with phospholipids incorporated in the organic phase before emulsification. Several phosp...

journal_title：Biomaterials

authors： Díaz-López R,Tsapis N,Libong D,Chaminade P,Connan C,Chehimi MM,Berti R,Taulier N,Urbach W,Nicolas V,Fattal E

更新日期：2009-03-01 00:00:00

abstract：:pH-sensitive degradable chimaeric polymersomes were developed based on asymmetric poly(ethylene glycol)-b-poly(2,4,6-trimethoxybenzylidene-1,1,1-tris(hydroxymethyl)ethane methacrylate)-b-poly(acrylic acid) (PEG-PTTMA-PAA) triblock copolymers for active loading as well as triggered intracellular release of hydrophilic ...

journal_title：Biomaterials

authors： Du Y,Chen W,Zheng M,Meng F,Zhong Z

更新日期：2012-10-01 00:00:00

abstract：:The authors have evaluated adhesive protein expression and cytokine production by human umbilical vein endothelial cells cultured in contact with polyethylene terephthalate (PET). ELAM-1, ICAM-1 and VCAM-1 expression was determined by flow cytometry; the concentration of interleukin-1 alpha (IL-1 alpha), interleukin-6...

journal_title：Biomaterials

authors： Cenni E,Granchi D,Ciapetti G,Verri E,Cavedagna D,Gamberini S,Di Leo A,Pizzoferrato A

更新日期：1996-11-01 00:00:00

abstract：:Stem cell culture is typically based on batch-type culture, which is laborious and expensive. Here, we propose a continuous harvest method for stem cells cultured on thermoresponsive nanobrush surfaces. In this method, stem cells are partially detached from the nanobrush surface by reducing the temperature of the cult...

journal_title：Biomaterials

authors： Peng IC,Yeh CC,Lu YT,Muduli S,Ling QD,Alarfaj AA,Munusamy MA,Kumar SS,Murugan K,Lee HC,Chang Y,Higuchi A

更新日期：2016-01-01 00:00:00

abstract：:Tissue-engineered skin substitutes provided a feasibility to overcome the shortage of skin autograft by culturing keratinocytes and dermal fibroblasts in vitro. In this study, we applied bi-layer gelatin-chondrointin-6-sulfate-hyaluronic acid (gelatin-C6S-HA) biomatrices onto the severe combined immunodeficiency (SCID...

journal_title：Biomaterials

authors： Wang TW,Sun JS,Wu HC,Tsuang YH,Wang WH,Lin FH

更新日期：2006-11-01 00:00:00