Abstract:
:A synthetic process for obtaining high-molecular-weight block copolymers containing poly(lactic-glycolic acid) and poly(ethylene glycol) segments has been established. This process involves the reaction of poly(ethylene glycols) with phosgene, followed by polycondensation of the resulting alpha, omega-bis(chloroformates) with poly(lactic-glycolic acid) oligomers. The copolymers have been characterized for their molecular weight, solubility properties, water absorption and preliminarily thermal behaviour. All evidence points to the conclusion that the process described is a general one, enabling biodegradable polymers to be obtained tailor-made according to specific requirements.
journal_name
Biomaterialsjournal_title
Biomaterialsauthors
Ferruti P,Penco M,D'Addato P,Ranucci E,Deghenghi Rdoi
10.1016/0142-9612(95)96879-5subject
Has Abstractpub_date
1995-12-01 00:00:00pages
1423-8issue
18eissn
0142-9612issn
1878-5905pii
0142-9612(95)96879-5journal_volume
16pub_type
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