Abstract：
:Hydrogels of crosslinked poly(2-vinylpyridine-1-oxide), PVNO, and poly(2-vinylpyridine-1-oxide)-poly(N-vinyl-pyrrolidone), PNVO-PVP, were synthesized. PVNO hydrogels were found to be degradable in a pseudo-biological medium and their stability could be increased by increasing the relative concentration of the crosslinking agent. PVNO-PVP hydrogels were also degradable and their stability could be increased by increasing the relative concentration of crosslinking agent and/or poly(N-vinylpyrrolidone). Swelling ratio and percent solvent content for both types of gels were determined. In addition, for PVNO-PVP gels, swelling properties in solvents with different dielectric constants, at different temperatures and ionic strengths were determined. Antibiotic releasing and water vapour behaviour were also investigated. From the data obtained, the free energy change involved in water vapour adsorption was calculated.
journal_name
Biomaterialsjournal_title
Biomaterialsauthors
Hasirci VNdoi
10.1016/0142-9612(81)90079-xsubject
Has Abstractpub_date
1981-01-01 00:00:00pages
3-8issue
1eissn
0142-9612issn
1878-5905pii
0142-9612(81)90079-Xjournal_volume
2pub_type
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