Influence of soluble suture factors on in vitro macrophage function.

abstract：:The in vitro labelling of cultured cells with iron oxide nanoparticles (NPs) is a frequent practice in biomedical research. To date, the potential cytotoxicity of these particles remains an issue of debate. In the present study, 4 different NP types (dextran-coated Endorem, carboxydextran-coated Resovist, lipid-coated...

journal_title：Biomaterials

authors： Soenen SJ,Himmelreich U,Nuytten N,De Cuyper M

更新日期：2011-01-01 00:00:00

abstract：:In-stent restenosis is one of the most serious modes of failure of cardiovascular stent implant. Although drug-eluting stents have been proven to reduce in-stent restenosis, the nonspecific inhibitory effects of anti-proliferative drugs, such as rapamycin, result in delayed re-endothelialization and fatal late stent t...

journal_title：Biomaterials

authors： Zhang H,Ren KF,Chang H,Wang JL,Ji J

更新日期：2017-02-01 00:00:00

abstract：:Biomaterials can potentially influence stem and progenitor cell proliferation and differentiation in both a positive and a negative way. Herein, we report on the expansion and differentiation of rat embryonic (E17) liver (RLC-18) cells on new bioactive membrane made of PEEK-WC-PU, whose surface was grafted with nitrog...

journal_title：Biomaterials

authors： Pavlica S,Piscioneri A,Peinemann F,Keller M,Milosevic J,Staeudte A,Heilmann A,Schulz-Siegmund M,Laera S,Favia P,De Bartolo L,Bader A

更新日期：2009-11-01 00:00:00

abstract：:Fluorapatite (FA)-collagen composites were synthesized via a biomimetic coprecipitation method in order to improve the structural stability and cellular responses. Different amounts of ammonium fluoride (NH4F), acting as a fluorine source for FA, were added to the precipitation of the composites. The precipitated comp...

journal_title：Biomaterials

authors： Yoon BH,Kim HW,Lee SH,Bae CJ,Koh YH,Kong YM,Kim HE

更新日期：2005-06-01 00:00:00

abstract：:In the design of parenteral delivery systems the modulation of the biodegradation of a polymer matrix represents a promising strategy to control drug release. We have investigated the degradation of ABA triblock copolymers, consisting of poly(lactide-co-glycolide) A-blocks and poly(oxyethylene) B-blocks, and PLG, poly...

journal_title：Biomaterials

authors： Witt C,Mäder K,Kissel T

更新日期：2000-05-01 00:00:00

abstract：:Non-invasive approaches to assess tissue function could improve significantly current methods to diagnose diseases and optimize engineered tissues. In this study, we describe a two-photon excited fluorescence microscopy approach that relies entirely on endogenous fluorophores to dynamically quantify functional metabol...

journal_title：Biomaterials

authors： Quinn KP,Bellas E,Fourligas N,Lee K,Kaplan DL,Georgakoudi I

更新日期：2012-07-01 00:00:00

abstract：:The currently available surgical options to repair the diaphragm are associated with significant risks of defect recurrence, lack of growth potential and restored functionality. A tissue engineered diaphragm has the potential to improve surgical outcomes for patients with congenital or acquired disorders. Here we show...

journal_title：Biomaterials

authors： Gubareva EA,Sjöqvist S,Gilevich IV,Sotnichenko AS,Kuevda EV,Lim ML,Feliu N,Lemon G,Danilenko KA,Nakokhov RZ,Gumenyuk IS,Grigoriev TE,Krasheninnikov SV,Pokhotko AG,Basov AA,Dzhimak SS,Gustafsson Y,Bautista G,Beltrán Ro

更新日期：2016-01-01 00:00:00

abstract：:Biomimetic materials that target the immune system and generate an anti-tumor responses hold promise in augmenting cancer immunotherapy. These synthetic materials can be engineered and optimized for their biodegradability, physical parameters such as shape and size, and controlled release of immune-modulators. As thes...

journal_title：Biomaterials

authors： Kosmides AK,Meyer RA,Hickey JW,Aje K,Cheung KN,Green JJ,Schneck JP

更新日期：2017-02-01 00:00:00

abstract：:High-density mesenchymal stem cell (MSC) aggregates can be guided to form bone-like tissue via endochondral ossification in vitro when culture media is supplemented with proteins, such as growth factors (GFs), to first guide the formation of a cartilage template, followed by culture with hypertrophic factors. Recent r...

journal_title：Biomaterials

authors： McMillan A,Nguyen MK,Gonzalez-Fernandez T,Ge P,Yu X,Murphy WL,Kelly DJ,Alsberg E

更新日期：2018-04-01 00:00:00

abstract：:The influence of processing-introduced flaws and heat treatment on the strength degradation of the dental core material has recently been observed. However, there are insufficient studies which investigate the role of grinding, grinding orientation, sandblasting, polishing and heat treatment on the strength of In-Cera...

journal_title：Biomaterials

authors： Guazzato M,Albakry M,Quach L,Swain MV

更新日期：2004-05-01 00:00:00

abstract：:Platelet concentrates (PCs) constitute new biological mediators used in osseous reconstructive surgery. In this study, we assessed (i) the effects of various concentrations of calcium and thrombin on the kinetics of platelet-derived growth factor (PDGF-BB), transforming growth factor-beta1(TGF-beta 1), basic fibroblas...

journal_title：Biomaterials

authors： Martineau I,Lacoste E,Gagnon G

更新日期：2004-08-01 00:00:00

abstract：:A surface graft polymer with one or two phosphorylcholine (PC) polarheads at the terminus of the growing chain end was prepared by sequential reactions on a glass substrate. The dithiocarbamate group covalently bound to glass surfaces was derivatized with one or two PC groups and then irradiated with ultraviolet light...

journal_title：Biomaterials

authors： Matsuda T,Kaneko M,Ge S

更新日期：2003-11-01 00:00:00

abstract：:Hydroxyapatite (HA) in 25%, 50% and 75% w/w fractions was incorporated into chitin solutions and processed into air- and freeze-dried materials. These HA-chitin materials were exposed to cell cultures and implanted into the intramusculature of a rat model. The HA-chitin materials were found to be non-cytotoxic and deg...

journal_title：Biomaterials

authors： Ge Z,Baguenard S,Lim LY,Wee A,Khor E

更新日期：2004-03-01 00:00:00

abstract：:Alzheimer's disease (AD) is characterized by the loss of neurogenesis and excessive induction of apoptosis. The induction of neurogenesis and inhibition of apoptosis may be a promising therapeutic approach to combating the disease. Celecoxib (CB), a cyclooxygenase-2 specific inhibitor, could offer neuroprotection. Spe...

journal_title：Biomaterials

authors： Guo JW,Guan PP,Ding WY,Wang SL,Huang XS,Wang ZY,Wang P

更新日期：2017-11-01 00:00:00

abstract：:The development of topical microbicides is a valid approach to protect the genital mucosa from sexually transmitted infections that cannot be contained with effective vaccination, like HSV and HIV infections. A suitable target of microbicides is the interaction between viral proteins and cell surface heparan sulfate p...

journal_title：Biomaterials

authors： Donalisio M,Quaranta P,Chiuppesi F,Pistello M,Cagno V,Cavalli R,Volante M,Bugatti A,Rusnati M,Ranucci E,Ferruti P,Lembo D

更新日期：2016-04-01 00:00:00

abstract：:Great efforts have been made to develop suitable bioactive constructs that release growth factors (GFs) in a controlled manner for tissue-regeneration applications. Platelet lysates (PLs) are an affordable source of multiple GFs and other proteins, and show great potential in the wound-healing process. Herein, poly-l-...

journal_title：Biomaterials

authors： Tang Q,Lim T,Wei XJ,Wang QY,Xu JC,Shen LY,Zhu ZZ,Zhang CQ

更新日期：2020-10-01 00:00:00

abstract：:The iron-containing fluoridated hydroxyapatites Fe-FeFAp and FeF-FeAp were synthesized heterogeneously in the presence of ferrous ions at 80 degrees C and pH 7.4 in two different types of solution, i.e. fluoride-free solution during the initial half of the experimental period and fluoride-containing solution during th...

journal_title：Biomaterials

authors： Okazaki M,Takahashi J

更新日期：1997-01-01 00:00:00

abstract：:Achieving and maintaining safe and reliable lineage specific differentiation of stem cells is important for clinical translation of tissue engineering strategies. In an effort to circumvent the multitude of problems arising from the usage of growth factors and growth factor delivery systems, we have explored the use o...

journal_title：Biomaterials

authors： Huang CC,Narayanan R,Alapati S,Ravindran S

更新日期：2016-12-01 00:00:00

abstract：:Microvessels of the blood-brain barrier (BBB) regulate transport into the brain. The highly specialized brain microvascular endothelial cells, a major component of the BBB, express tight junctions and efflux transporters which regulate paracellular and transcellular permeability. However, most existing models of BBB m...

journal_title：Biomaterials

authors： Linville RM,DeStefano JG,Sklar MB,Xu Z,Farrell AM,Bogorad MI,Chu C,Walczak P,Cheng L,Mahairaki V,Whartenby KA,Calabresi PA,Searson PC

更新日期：2019-01-01 00:00:00

abstract：:High-molecular-weight polyethylenimine (25 kDa, PEI25k) is one of the most common cationic polymers utilized in non-viral gene therapy. However, its methylene backbone (-CH(2)CH(2)N(x)-) and high charge density can result in poor biodegradability and high toxicity to cells. We hypothesize that optimizing the polymer l...

journal_title：Biomaterials

authors： Xiong MP,Forrest ML,Ton G,Zhao A,Davies NM,Kwon GS

更新日期：2007-11-01 00:00:00

abstract：:The long-term behaviour of cellulose sponge implants, 10 x 10 x 5 mm in size, and tissue reactions in and around them were examined in the subcutaneous tissue of the rat from 1 to 60 weeks after implantation. The cellulose sponge used was filled up with connective tissue 4 to 8 weeks after implantation. Histologically...

journal_title：Biomaterials

authors： Märtson M,Viljanto J,Hurme T,Laippala P,Saukko P

更新日期：1999-11-01 00:00:00

abstract：:The aim of this study was to determine the biocompatibility and osteoconductive potential of a high-strength canasite glass ceramic. Glass-ceramic rods were produced using the lost-wax casting technique and implanted in the mid-shafts rabbit femurs. Implants were harvested at 4, 13 and 22 weeks and prepared for light ...

journal_title：Biomaterials

authors： da Rocha Barros VM,Salata LA,Sverzut CE,Xavier SP,van Noort R,Johnson A,Hatton PV

更新日期：2002-07-01 00:00:00

abstract：:Stimuli-responsive nanoparticles hold great promise for drug delivery to improve the safety and efficacy of cancer therapy. One of the most investigated stimuli-responsive strategies is to induce drug release by heating with laser, ultrasound, or electromagnetic field. More recently, cryosurgery (also called cryothera...

journal_title：Biomaterials

authors： Wang H,Agarwal P,Liang Y,Xu J,Zhao G,Tkaczuk KHR,Lu X,He X

更新日期：2018-10-01 00:00:00

abstract：:Polyphosphazenes have been synthesized with tris(hydroxymethyl)amino methane (THAM) side groups and with co-substituents glycine ethyl ester and alanine ethyl ester. The THAM side group was linked to the polyphosphazene backbone via the amino function. The three pendent hydroxyl functions on each THAM side group were ...

journal_title：Biomaterials

authors： Krogman NR,Weikel AL,Kristhart KA,Nukavarapu SP,Deng M,Nair LS,Laurencin CT,Allcock HR

更新日期：2009-06-01 00:00:00

abstract：:The sintering behavior of calcium pyrophosphate (CPP, Ca2P2O7)-doped beta-tricalcium phosphate [TCP, Ca3(PO4)2], prepared by solid state reaction, was investigated in-situ, using dilatometry. Pure beta-TCP undergoes phase transition to alpha-TCP at about 1200 degrees C; hence pure beta-TCP ceramics should be sintered ...

journal_title：Biomaterials

authors： Ryu HS,Youn HJ,Hong KS,Chang BS,Lee CK,Chung SS

更新日期：2002-02-01 00:00:00

abstract：:Ultra-high molecular-weight polyethylene (UHMWPE) has been used in total joint replacement for the last three decades. Despite the recent advancements in prosthesis design, the wear of UHMWPE remains a serious clinical problem; the release of wear debris may induce osteolysis and implant loosening. Controlling the qua...

journal_title：Biomaterials

authors： Affatato S,Bersaglia G,Emiliani D,Foltran I,Taddei P,Reggiani M,Ferrieri P,Toni A

更新日期：2003-10-01 00:00:00

abstract：:We report the stimulation of neurogenesis and myogenesis of human mesenchymal stem cells (hMSCs) on the surfaces of biodegradable hydrogels with different stiffness. The hydrogels were composed of gelatin-hydroxyphenylpropionic acid (Gtn-HPA) conjugate were formed using the oxidative coupling of phenol moieties cataly...

journal_title：Biomaterials

authors： Wang LS,Boulaire J,Chan PP,Chung JE,Kurisawa M

更新日期：2010-11-01 00:00:00

abstract：:A limitation with the use of polymers as stent matrices is their inherent mechanical weakness. In this study, a polymeric stent, made from chitosan-based films fixed by genipin which has a cyclic molecular structure, was developed (the genipin stent). The mechanical properties of the genipin stent were investigated; i...

journal_title：Biomaterials

authors： Chen MC,Liu CT,Tsai HW,Lai WY,Chang Y,Sung HW

更新日期：2009-10-01 00:00:00

abstract：:Keratins are a family of structural proteins that can be isolated from a variety of tissues. "Soft" keratins are cytoskeletal elements found in epithelial tissues while protective tissues such as nails, hooves, and hair are composed of "hard" keratins. Hard keratins have been the subject of biomaterials investigations...

journal_title：Biomaterials

authors： Hill P,Brantley H,Van Dyke M

更新日期：2010-02-01 00:00:00

abstract：:Material features proved to exert a potent influence on cell behaviour in terms of adhesion, migration and differentiation. In particular, biophysical and biochemical signals on material surfaces are able to affect focal adhesion distribution and cytoskeletal assemblies, which are known to regulate signalling pathways...

journal_title：Biomaterials

authors： Natale CF,Ventre M,Netti PA

更新日期：2014-03-01 00:00:00