Phagocytosis of latex particles by leucocytes. I. Dependence of phagocytosis on the size and surface potential of particles.

abstract：:IR-780 iodide is a near-infrared (NIR) fluorescence dye with higher and more stable fluorescence intensity than clinically applied dye indocyanine green (ICG). Meanwhile, IR-780 can be utilized in photothermal therapy with laser irradiation. IR-780 is an important theranostic agent but its lipophilicity limited its ap...

journal_title：Biomaterials

authors： Yue C,Liu P,Zheng M,Zhao P,Wang Y,Ma Y,Cai L

更新日期：2013-09-01 00:00:00

abstract：:Measurements were made of the extremes in temperature which occur at different sites in the oral cavity during fluid intake. The results indicate that temperatures noted at the tooth surface, within the mouth, during fluid intake were less than the temperatures of the fluid imbibed. Variations in temperature were note...

journal_title：Biomaterials

authors： Longman CM,Pearson GJ

更新日期：1987-09-01 00:00:00

abstract：:Immune checkpoint blocking (ICB) antibodies have shown great success in the clinic, but their low response rate in patients with immunosuppressive cold tumors remains a huge challenge. Inspired by the capability of immunogenic cell death (ICD) to convert tumors from cold to hot, we developed a corn-like Au/Ag nanorod ...

journal_title：Biomaterials

authors： Jin L,Shen S,Huang Y,Li D,Yang X

更新日期：2021-01-01 00:00:00

abstract：:A number of phase separation pHEMA sponge hydrogels have been prepared based on variations in monomer contents, concentration of cross-linking agent, solvent mixture and temperature of polymerization. The loading levels and release profiles of the anti-inflammatory drug prednisolone were examined for each of the pHEMA...

journal_title：Biomaterials

authors： Lou X,Munro S,Wang S

更新日期：2004-09-01 00:00:00

abstract：:Neurotrophic factors therapy requires their precise delivery to the targeted neuronal population. For this purpose, a wide range of strategies have been developed, and among them the stereotaxic implantation of biodegradable microparticles. To assess the in vivo activity of NGF-releasing PLGA microspheres, unloaded an...

journal_title：Biomaterials

authors： Péan JM,Menei P,Morel O,Montero-Menei CN,Benoit JP

更新日期：2000-10-01 00:00:00

abstract：:Hydrogels are commonly used as artificial extracellular matrices for 3D cell culture and for tissue engineering. Viscoelastic hydrogels with tunable stress relaxation have recently been developed, and stress relaxation in the hydrogels has been found to play a key role in regulating cell behaviors such as differentiat...

journal_title：Biomaterials

authors： Nam S,Stowers R,Lou J,Xia Y,Chaudhuri O

更新日期：2019-04-01 00:00:00

abstract：:The use of a composite graft of bovine trabecular demineralized bone matrix (DBM) and perichondrium has been found a reliable method for in vivo generation of cartilage. In the present study, the mechanism whereby this commercially available matrix increases cartilage formation was investigated. First, the time course...

journal_title：Biomaterials

authors： van Osch GJ,ten Koppel PG,van der Veen SW,Poppe P,Burger EH,Verwoerd-Verhoef HL

更新日期：1999-02-01 00:00:00

abstract：:We investigated the feasibility and efficacy of target thrombolysis with recombinant tissue plasminogen activator (rtPA) covalently bound to magnetic nanoparticle (MNP) and retained to the target site in vivo by an external magnet. Polyacrylic acid-coated magnetite (PAA-MNP, 246 nm) was synthesized and characterized; ...

journal_title：Biomaterials

authors： Ma YH,Wu SY,Wu T,Chang YJ,Hua MY,Chen JP

更新日期：2009-07-01 00:00:00

abstract：:The design of peptide-based subunit vaccine formulations for the direct delivery of tumor antigen peptides (Aps) to dendritic cells (DCs) localized within draining lymph nodes (DLNs) is challenging. Mature DCs (mDCs) are abundantly distributed within DLNs but have dramatically reduced endocytic uptake and antigen-proc...

journal_title：Biomaterials

authors： Qian Y,Jin H,Qiao S,Dai Y,Huang C,Lu L,Luo Q,Zhang Z

更新日期：2016-08-01 00:00:00

abstract：:Magnetic microcarrier particles useful for delivering chemotherapeutic drug molecules are described. The particles are formed by joint deformation of iron and carbon in a ball mill. Physical, chemical, and functional characterization has been carried out on the particles. Physical characteristics include microscopy, p...

journal_title：Biomaterials

authors： Rudge SR,Kurtz TL,Vessely CR,Catterall LG,Williamson DL

更新日期：2000-07-01 00:00:00

abstract：:Levels of corrosion products released from dental alloys in natural or synthetic saliva, i.e. from amalgams, cobalt, gold, nickel, iron, or titanium based alloys have been surveyed. The amounts of Ag, Au, Cd, Co, Cr, Cu, Hg, Mo, Ti or Ni released from such alloys, either in vitro or in vivo during animal tests or duri...

journal_title：Biomaterials

authors： Brune D

更新日期：1986-05-01 00:00:00

abstract：:In this paper we report a method for biomaterial surface modification that utilizes the self-assembly of block copolymers of poly(styrene-block-ethylene oxide) (PS-PEO) to generate micro-phase separated surfaces with varying density PEO domains. These PS-PEO self-assembled surfaces showed a significant reduction in pr...

journal_title：Biomaterials

authors： George PA,Donose BC,Cooper-White JJ

更新日期：2009-05-01 00:00:00

abstract：:This study investigated a strategy by which antibodies are displayed to engage T cells. A peptide composite containing binding sites was characterized in vitro and explored as an injectable system in vivo. The composite consists of two amphiphilic peptides, AEAEAKAKAEAEAKAK (referred to as "EAK") and EAK appended with...

journal_title：Biomaterials

authors： Zheng Y,Wen Y,George AM,Steinbach AM,Phillips BE,Giannoukakis N,Gawalt ES,Meng WS

更新日期：2011-01-01 00:00:00

abstract：:Calcium phosphate (CaP) based approaches remain an attractive option for delivering plasmid DNA (pDNA) into cultured cells. However, despite their appeal, current synthesis methodologies typically yield lower, less consistent transfection efficiencies when compared to viral approaches. Therefore, we report here a nove...

journal_title：Biomaterials

authors： Olton D,Li J,Wilson ME,Rogers T,Close J,Huang L,Kumta PN,Sfeir C

更新日期：2007-02-01 00:00:00

abstract：:Targeted tumor imaging and efficient specific gene delivery in vivo has been one of the main challenges in gene-based cancer diagnosis and therapy. Herein, we engineered a citric acid-based polymer with intrinsical photoluminescence and gene loading capacity to achieve targeted delivery of siRNA and tumor imaging in v...

journal_title：Biomaterials

authors： Wang M,Guo Y,Xue Y,Niu W,Chen M,Ma PX,Lei B

更新日期：2019-04-01 00:00:00

abstract：:mRNA-based vaccines have the benefit of triggering robust anti-cancer immunity without the potential danger of genome integration from DNA vaccines or the limitation of antigen selection from peptide vaccines. Yet, a conventional mRNA vaccine comprising of condensed mRNA molecules in a positively charged protein core ...

journal_title：Biomaterials

authors： Persano S,Guevara ML,Li Z,Mai J,Ferrari M,Pompa PP,Shen H

更新日期：2017-05-01 00:00:00

abstract：:Ferroptosis, a newfound non-apoptotic cell death pathway, results from the accumulation of iron-dependent lipid peroxide (LPO). Recently, emerging iron-based nanomaterials have been extensively developed to induce Fenton reaction-dependent ferroptosis for cancer therapy. However, insufficient amount of H2O2 and limite...

journal_title：Biomaterials

authors： He YJ,Liu XY,Xing L,Wan X,Chang X,Jiang HL

更新日期：2020-05-01 00:00:00

abstract：:The production profile of interleukin 1 (IL-1) from mouse peritoneal macrophages (M phi) was determined following their incubation with poly(DL-lactic acid) (PDLLA) granules containing ovalbumin (OVA). Upon incubation, M phi produced IL-1 at a significantly high rate compared with those incubated with OVA in the free ...

journal_title：Biomaterials

authors： Nakaoka R,Tabata Y,Ikada Y

更新日期：1996-12-01 00:00:00

abstract：UNLABELLED:Scarcity of donor tissue to treat corneal blindness and the need to deliver stem cells or pharmacologic agents to ensure corneal graft survival are major challenges. Here, new composite collagen-based hydrogels are developed as implants to restore corneal transparency while serving as a possible reservoir fo...

journal_title：Biomaterials

authors： Rafat M,Xeroudaki M,Koulikovska M,Sherrell P,Groth F,Fagerholm P,Lagali N

更新日期：2016-03-01 00:00:00

abstract：:The dynamic regulation of integrin-binding peptides is crucial for chondrogenic differentiation. Here, we revealed the feasibility for flexible modification of RGD by embedding a large molecular weight and slightly charged (isoelectric point, 6-6.25) RGD-chimeric protein (CBD-RGD) with cellulose-binding domain (CBD) i...

journal_title：Biomaterials

authors： Chang JC,Hsu SH,Chen DC

更新日期：2009-10-01 00:00:00

abstract：:Aim of the study was to examine if the addition of buffering sodiumhydrogenphosphate to poly(D,L)lactide(PDLLA) would stabilize the pH-value in the in vivo environment of implanted material and whether this improves its biocompatibility. The material was predegraded just to the point of viscous disintegration to test ...

journal_title：Biomaterials

authors： Heidemann W,Jeschkeit-Schubbert S,Ruffieux K,Fischer JH,Jung H,Krueger G,Wintermantel E,Gerlach KL

更新日期：2002-09-01 00:00:00

abstract：:Two types of cells--human platelets and spore cells--were encapsulated in polymer shells by adsorbing polyanions and polycations in a stepwise fashion. The encapsulated cells were attached to gold and silicon surfaces and their morphological and adhesion properties were studied in air using tapping mode atomic force m...

journal_title：Biomaterials

authors： Yu M,Ivanisevic A

更新日期：2004-08-01 00:00:00

abstract：:Nanobubbles, as a kind of new ultrasound contrast agent (UCAs), have shown promise to penetrate tumor vasculature to allow for targeted imaging. However, their inherent physical instability is an ongoing concern that could weaken their imaging ability with ultrasound. Gas vesicles (GVs), which are genetically encoded,...

journal_title：Biomaterials

authors： Wang G,Song L,Hou X,Kala S,Wong KF,Tang L,Dai Y,Sun L

更新日期：2020-04-01 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) play an important role in regulating osteoblastic differentiation and bone formation. But the diffuse of BMPs into muscle tissues around bone injury sites often leads to heterotopic ossification, which has been regarded as one of major side-effects of BMP implementation in bone defec...

journal_title：Biomaterials

authors： Zhang J,Zhao Y,Hou X,Chen B,Xiao Z,Han J,Shi C,Liu J,Miao Q,Dai J

更新日期：2014-11-01 00:00:00

abstract：:It is estimated that 4 to 5 million people are currently co-infected with Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV). HIV/HCV co-infection is associated with unique health risks including increased hepatotoxicity of antiretrovirals, accelerated progression of HCV and liver diseases. The standard in...

journal_title：Biomaterials

authors： Zhang J,Mulvenon A,Makarov E,Wagoner J,Knibbe J,Kim JO,Osna N,Bronich TK,Poluektova LY

更新日期：2013-05-01 00:00:00

abstract：:The phenomenon of light-induced cell detachment is reported. Mouse calvaria-derived, pre-osteoblastic (MC3T3-E1) cells were cultured on a TiO(2) nanodot-coated quartz substrate. After 20 min of UV365 illumination, over 90% of the cells would detach from the surface. Moreover, intact cell sheets could be obtained in th...

journal_title：Biomaterials

authors： Hong Y,Yu M,Weng W,Cheng K,Wang H,Lin J

更新日期：2013-01-01 00:00:00

abstract：:Knee arthroplasty has reached a high degree of reliability. Many of the remaining long-term loosening cases are due to the polyethylene wear debris. The introduction of the alumina ceramic to polyethylene bearing couple had been a promising means for its reduction. The discussion of its applications in total knee repl...

journal_title：Biomaterials

authors： Heimke G,Leyen S,Willmann G

更新日期：2002-04-01 00:00:00

abstract：:A series of in vitro screening assays for the preliminary selection of biomaterials for use in the fabrication of artificial corneas (keratoprostheses) (KPros) have been investigated. These screening assays assessed the initial binding of inflammatory and cell adhesive proteins, activation of inflammatory proteins, ad...

journal_title：Biomaterials

authors： Sandeman SR,Lloyd AW,Tighe BJ,Franklin V,Li J,Lydon F,Liu CS,Mann DJ,James SE,Martin R

更新日期：2003-11-01 00:00:00

abstract：:In situ gelating dextran-tyramine (Dex-TA) injectable hydrogels have previously shown promising features for cartilage repair. Yet, despite suitable mechanical properties, this system lacks intrinsic biological signals. In contrast, platelet lysate-derived hydrogels are rich in growth factors and anti-inflammatory cyt...

journal_title：Biomaterials

authors： Moreira Teixeira LS,Leijten JC,Wennink JW,Chatterjea AG,Feijen J,van Blitterswijk CA,Dijkstra PJ,Karperien M

更新日期：2012-05-01 00:00:00

abstract：:Poly(epsilon-caprolactone) (PCL)/continuous bioglass fibre composite was prepared using the monomer transfer moulding technique coupled with a surface initiated polymerisation. The bioglass fibres were surface treated with an amine ended silane in order to initiate polymerisation of epsilon-caprolactone from the fibre...

journal_title：Biomaterials

authors： Jiang G,Evans ME,Jones IA,Rudd CD,Scotchford CA,Walker GS

更新日期：2005-05-01 00:00:00