Preparation, characterization, and performance of magnetic iron-carbon composite microparticles for chemotherapy.

abstract：:Exploring the interactions between the immune system and nanomaterials (NMs) is critical for designing effective and safe NMs, but large knowledge gaps remain to be filled prior to clinical applications (e.g., immunotherapy). The lack of databases on interactions between the immune system and NMs affects the discovery...

journal_title：Biomaterials

authors： Feng R,Yu F,Xu J,Hu X

更新日期：2021-01-01 00:00:00

abstract：:By use of scanning electron microscopy (SEM), together with energy dispersive chemical analysis, a study has been made of the comparison of an in vitro method of assessing interface reactions between bone and ceramic implants with the naturally occurring changes seen in the rat ear model. Interface reactions between b...

journal_title：Biomaterials

authors： Williams KR,Blayney AW,Frootko NJ,Ashton BA

更新日期：1985-07-01 00:00:00

abstract：:Synthetic hydroxyapatite particles of two median sizes and different morphologies have been used to manufacture hydroxyapatite reinforced high density polyethylene composites (HAPEX) for medical applications. The effects of hydroxyapatite particle size on properties of the resultant composites were investigated using ...

journal_title：Biomaterials

authors： Wang M,Joseph R,Bonfield W

更新日期：1998-12-01 00:00:00

abstract：:Implantation of synthetic material, including vascular grafts, pacemakers, etc. results in the foreign body reaction and the formation of multinucleated giant cells (MGCs) at the exterior surface of the implant. Despite the long-standing premise that fusion of mononucleated macrophages results in the formation of MGCs...

journal_title：Biomaterials

authors： Faust JJ,Christenson W,Doudrick K,Ros R,Ugarova TP

更新日期：2017-06-01 00:00:00

abstract：:Surface plasmon resonance (SPR) sensing has long been used to study biomolecular binding events and their kinetics in a label-free way. This approach has recently been extended to SPR microscopy, which is an ideal tool for probing large microarrays of biomolecules for their binding interactions with various partners a...

journal_title：Biomaterials

authors： Campbell CT,Kim G

更新日期：2007-05-01 00:00:00

abstract：:The commercial availability of peptides and proteins and their advantages as therapeutic agents have been the basis for tremendous efforts in designing delivery systems for such agents. The protection of these agents from biological fluids and physiological interactions is crucial for the treatment efficacy. One such ...

journal_title：Biomaterials

authors： Torres-Lugo M,Peppas NA

更新日期：2000-06-01 00:00:00

abstract：:The limited intrinsic repair capacity of articular cartilage has stimulated continuing efforts to develop tissue engineered analogues. Matrices composed of type II collagen and chondroitin sulfate (CS), the major constituents of hyaline cartilage, may create an appropriate environment for the generation of cartilage-l...

journal_title：Biomaterials

authors： Pieper JS,van der Kraan PM,Hafmans T,Kamp J,Buma P,van Susante JL,van den Berg WB,Veerkamp JH,van Kuppevelt TH

更新日期：2002-08-01 00:00:00

abstract：:Poly(epsilon-caprolactone) (PCL)/continuous bioglass fibre composite was prepared using the monomer transfer moulding technique coupled with a surface initiated polymerisation. The bioglass fibres were surface treated with an amine ended silane in order to initiate polymerisation of epsilon-caprolactone from the fibre...

journal_title：Biomaterials

authors： Jiang G,Evans ME,Jones IA,Rudd CD,Scotchford CA,Walker GS

更新日期：2005-05-01 00:00:00

abstract：:Subtle changes on the surface of polymeric materials on autoclaving have been ignored so far. An increase in cyclic trimer content on the surface of polyethylene terephthalate on autoclaving is reported. This increase may affect the biocompatibility of polyethylene terephthalate. Quantification of the cyclic trimer wa...

journal_title：Biomaterials

authors： Nair PD,Sreenivasan K

更新日期：1984-09-01 00:00:00

abstract：:Primary stability and an optimized load transfer are assumed to account for an undisturbed osseointegration process of implants. Immediate loaded newly designed titanium dental implants inserted in the mandible of minipigs were used for the characterization of the interfacial area between the implant surface and the s...

journal_title：Biomaterials

authors： Meyer U,Joos U,Mythili J,Stamm T,Hohoff A,Fillies T,Stratmann U,Wiesmann HP

更新日期：2004-05-01 00:00:00

abstract：:It is well known that biomaterials play an important role in the regulation of adhesion and growth of a variety of cultured cell types. However, whether biomaterials are associated with the senescence of cultured cells is not known. The present work shows that the decrease of the hydrophobic property of poly (ethylene...

journal_title：Biomaterials

authors： Lou PJ,Chiu MY,Chou CC,Liao BW,Young TH

更新日期：2010-03-01 00:00:00

abstract：:Retinal degeneration impairs the vision of millions in all age groups worldwide. Increasing evidence suggests that the etiology of many retinal degenerative diseases is associated with impairment in biochemical reactions involved in the visual cycle, a metabolic pathway responsible for regeneration of the visual chrom...

journal_title：Biomaterials

authors： Puntel A,Maeda A,Golczak M,Gao SQ,Yu G,Palczewski K,Lu ZR

更新日期：2015-03-01 00:00:00

abstract：:Adipose-derived stem cells (ASCs) hold promise for bone regeneration but possess inferior osteogenesis potential. Allotransplantation of ASCs engineered with the BMP2/VEGF-expressing baculoviruses into rabbits healed critical-size segmental bone defects. To translate the technology to clinical applications, we aimed t...

journal_title：Biomaterials

authors： Lin CY,Wang YH,Li KC,Sung LY,Yeh CL,Lin KJ,Yen TC,Chang YH,Hu YC

更新日期：2015-05-01 00:00:00

abstract：:This article is a review of recent developments of polymer-related stents mainly employed in the coronary arteries, including polymer-coated stents, biostable stents and biodegradable stents. Polymer paving is covered as well. The problems with the stents currently investigated and the development of new stents are di...

journal_title：Biomaterials

authors： Peng T,Gibula P,Yao KD,Goosen MF

更新日期：1996-04-01 00:00:00

abstract：:Recent studies have shown that extracellular matrix (ECM) substitutes can have a dramatic impact on cell growth, differentiation and function. However, these ECMs are often applied generically and have yet to be developed for specific cell types. In this study, we developed tissue-specific ECM-based coating substrates...

journal_title：Biomaterials

authors： Zhang Y,He Y,Bharadwaj S,Hammam N,Carnagey K,Myers R,Atala A,Van Dyke M

更新日期：2009-08-01 00:00:00

abstract：:The present study investigated the ectopic osteoinduction and early degradation of recombinant human bone morphogenetic protein-2 (rhBMP-2)-loaded porous beta-tricalcium phosphate (beta-TCP) in mice. The porous beta-TCP with 50 microg of rhBMP-2 (n = 25) and porous beta-TCP (control group, n = 25) were implanted into ...

journal_title：Biomaterials

authors： Liang G,Yang Y,Oh S,Ong JL,Zheng C,Ran J,Yin G,Zhou D

更新日期：2005-07-01 00:00:00

abstract：:Driven by the clinical need for a strong tissue adhesive with elastomeric material properties, a departure from legacy crosslinking chemistries was sought as a multipurpose platform for tissue mending. A fresh approach to bonding wet substrates has yielded a synthetic biomaterial that overcomes the drawbacks of free-r...

journal_title：Biomaterials

authors： Djordjevic I,Pokholenko O,Shah AH,Wicaksono G,Blancafort L,Hanna JV,Page SJ,Nanda HS,Ong CB,Chung SR,Chin AYH,McGrouther D,Choudhury MM,Li F,Teo JS,Lee LS,Steele TWJ

更新日期：2020-11-01 00:00:00

abstract：:In spite of tremendous demand for the development and implementation of effective therapeutic strategies, limitations are still associated with doxorubicin-induced cardiotoxicity. Arjunolic acid (AA) has been shown to possess a multitude of biological functions. The purpose of the present study was to explore whether ...

journal_title：Biomaterials

authors： Ghosh J,Das J,Manna P,Sil PC

更新日期：2011-07-01 00:00:00

abstract：:Astroglial cell survival and ion channel activity are relevant molecular targets for the mechanistic study of neural cell interactions with biomaterials and/or electronic interfaces. Astrogliosis is the most typical reaction to in vivo brain implants and needs to be avoided by developing biomaterials that preserve ast...

journal_title：Biomaterials

authors： Benfenati V,Toffanin S,Capelli R,Camassa LM,Ferroni S,Kaplan DL,Omenetto FG,Muccini M,Zamboni R

更新日期：2010-11-01 00:00:00

abstract：:A major hindrance in islet transplantation as a feasible therapeutic approach for patients with type 1 diabetes is the insufficient oxygenation of the grafts, which results in cell death in portions of the implant. Here we address this limitation through the application of oxygen-generating microparticles (MP) and a f...

journal_title：Biomaterials

authors： Montazeri L,Hojjati-Emami S,Bonakdar S,Tahamtani Y,Hajizadeh-Saffar E,Noori-Keshtkar M,Najar-Asl M,Ashtiani MK,Baharvand H

更新日期：2016-05-01 00:00:00

abstract：:We previously reported that modification of GALA peptide on the surface of liposomes enhanced fusion with endosomal membrane, and cytoplasmic release of encapsulated macromolecules. We report herein that an additional coating of GALA-modified liposomes with 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer result...

journal_title：Biomaterials

authors： Ukawa M,Akita H,Masuda T,Hayashi Y,Konno T,Ishihara K,Harashima H

更新日期：2010-08-01 00:00:00

abstract：:Acute and chronic wounds affect millions and are associated with billions of dollars in healthcare costs. The use of healing markers, biochemical cues from biocompatible matrices and materials, and their correlation with wound healing has the potential to generate valuable diagnostic, prognostic, and therapeutic infor...

journal_title：Biomaterials

authors： Roussakis E,Ortines RV,Pinsker BL,Mooers CT,Evans CL,Miller LS,Calderón-Colón X

更新日期：2019-08-01 00:00:00

abstract：:Medical implants used in oral and orthopaedic surgery are mainly produced from titanium. Their biological behaviour, e.g. osseointegration, essentially depends on both the chemical composition and the morphology of the surface. Modifications achieved by excimer laser irradiation of titanium samples were investigated i...

journal_title：Biomaterials

authors： Bereznai M,Pelsöczi I,Tóth Z,Turzó K,Radnai M,Bor Z,Fazekas A

更新日期：2003-10-01 00:00:00

abstract：:Based on the hypothesis that bone cements cause changes in the production of transforming growth factor-beta 1 (TGF-beta1) by bone cells, the effects of four acrylic bone cements (Sulfix-60, CMW 1, CMW 2 and CMW 3) were examined using the osteoblast-like cell line MG63. The extracts in MEM of the cements were tested, ...

journal_title：Biomaterials

authors： Cenni E,Granchi D,Ciapetti G,Savarino L,Corradini A

更新日期：2002-01-01 00:00:00

abstract：:Facile assembly of intelligent DNA nanoobjects with the ability to exert in situ visualization of intracellular microRNAs (miRNAs) has long been concerned in the fields of DNA nanotechnology and basic medical study. Here, we present a driving primer (DP)-triggered polymerization-mediated metastable assembly (PMA) stra...

journal_title：Biomaterials

authors： Xu J,Wu ZS,Wang Z,Le J,Zheng T,Jia L

更新日期：2017-03-01 00:00:00

abstract：:Mesenchymal stromal cells (hMSCs) are advancing into the clinic but the therapeutic efficacy of hMSCs faces the problem of donor variability. In bone tissue engineering, no reliable markers have been identified which are able to predict the bone-forming capacity of hMSCs prior to implantation. To this end, we isolated...

journal_title：Biomaterials

authors： Mentink A,Hulsman M,Groen N,Licht R,Dechering KJ,van der Stok J,Alves HA,Dhert WJ,van Someren EP,Reinders MJ,van Blitterswijk CA,de Boer J

更新日期：2013-06-01 00:00:00

abstract：:Certain types of implanted medical devices depend on oxygen supplied from surrounding tissues for their function. However, there is a concern that the tissue associated with the foreign body response to implants may become impermeable to oxygen over the long term and render the implant nonfunctional. We report oxygen ...

journal_title：Biomaterials

authors： Kumosa LS,Routh TL,Lin JT,Lucisano JY,Gough DA

更新日期：2014-09-01 00:00:00

abstract：:Doxorubicin (DOX) is a well-known anticancer drug used for the treatment of a wide variety of cancers. However, undesired toxicity of DOX limits its uses. To address the issue of minimizing toxicity of DOX by making it targeted towards cancer cells, DOX was entrapped in self-assembled 6-O-(3-hexadecyloxy-2-hydroxyprop...

journal_title：Biomaterials

authors： Ray L,Kumar P,Gupta KC

更新日期：2013-04-01 00:00:00

abstract：:Scaffold design plays a crucial role in developing graft-based regenerative strategies, especially when intended to be used in a highly ordered nerve tissue. Here we describe a hybrid matrix approach, which combines the structural properties of collagen (type I) with the epitope-presenting ability of peptide amphiphil...

journal_title：Biomaterials

authors： Sur S,Pashuck ET,Guler MO,Ito M,Stupp SI,Launey T

更新日期：2012-01-01 00:00:00

abstract：:Nickel-titanium shape-memory alloys (NiTi-SMA) were coated with calcium phosphate by dipping in oversaturated calcium phosphate solution. The layer thickness (typically 5-20 micrometer) can be varied by choice of the immersion time. The porous nature of the layer of microcrystals makes it mechanically stable enough to...

journal_title：Biomaterials

authors： Choi J,Bogdanski D,Köller M,Esenwein SA,Müller D,Muhr G,Epple M

更新日期：2003-09-01 00:00:00