当前位置： SCI文献检索 > EXPERIMENTAL PARASITOLOGY期刊下所有文献 > Comparison of pathology in susceptible A/J and resistant C57BL/6J mice after infection with different sub-strains of Plasmodium chabaudi.

Comparison of pathology in susceptible A/J and resistant C57BL/6J mice after infection with different sub-strains of Plasmodium chabaudi.

Abstract：

:Susceptible A/J and more resistant C57BL/6J mice were infected with Plasmodium chabaudi chabaudi 54X, P.c. chabaudi AS and Plasmodium chabaudi adami 408XZ. As expected, most C57BL/6J mice survived the infections with the different isolates. But in contrast to previous observations, not all A/J mice succumbed to infection: just over 50% of A/J mice survived infections with P.c. chabaudi 54X, while 80% survived P.c. chabaudi AS. The more virulent parasite, P.c. adami 408XZ, was able to kill all A/J mice and 20% of C57BL/6J mice after an intravenous infection with 10(5) pRBC. A detailed study of four parameters of pathology (body weight, body temperature, blood glucose and RBC counts) in both mouse strains after a P.c. adami 408XZ infection showed similar patterns to those previously reported after infection with P.c. chabaudi AS. These data suggest that environmental factors as well as parasite polymorphisms might influence the severity of malaria between susceptible and resistant mice.

journal_name

Exp Parasitol

journal_title

Experimental parasitology

authors

Hernandez-Valladares M,Naessens J,Nagda S,Musoke AJ,Rihet P,Ole-Moiyoi OK,Iraqi FA

doi

10.1016/j.exppara.2004.07.011

keywords:

subject

Has Abstract

pub_date

2004-11-01 00:00:00

pages

134-41

issue

3-4

eissn

0014-4894

issn

1090-2449

pii

S0014-4894(04)00126-2

journal_volume

108

pub_type

杂志文章

相关文献

EXPERIMENTAL PARASITOLOGY文献大全
  • Small animal in vivo imaging of parasitic infections: A systematic review.

    abstract：:Non-invasive small animal in vivo imaging is an essential tool in a broad variety of biomedical sciences and enables continuous monitoring of disease progression in order to develop and improve diagnostic, therapeutic and preventive measures. Imaging parasites non-invasively in live animals allows efficient parasite d...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2020.107905

    authors： Novobilský A,Höglund J

    更新日期：2020-07-01 00:00:00

  • Oxidative stress associated with pathological lesions in the liver of rats experimentally infected by Fasciola hepatica.

    abstract：:The aim of this study was to analyze the antioxidant status and oxidative profile in serum and liver of rats experimentally infected with Fasciola hepatica and its relationship with pathological findings. Twenty-four rats were divided into two groups: group A consisted of 12 healthy rats and group B of 12 rats infecte...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2015.08.008

    authors： Bottari NB,Mendes RE,Lucca NJ,Schwertz CI,Henker LC,Olsson DC,Piva MM,Sangoi M,Campos LP,Moresco RN,Jaques JA,Da silva AS

    更新日期：2015-12-01 00:00:00

  • Schistosoma mansoni: cercarial eicosanoid production and penetration response inhibited by esculetin and ibuprofen.

    abstract：:Cercariae of Schistosoma mansoni produce a wide variety of eicosanoids when stimulated by 3.3 mM linoleate. High-performance liquid chromatography indicated that 10(-5) M esculetin dramatically decreased eicosanoid production by cercariae. Ibuprofen (10(-4) M) also decreased eicosanoid production, but to a lesser exte...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/s0014-4894(85)80024-2

    authors： Salafsky B,Fusco AC

    更新日期：1985-08-01 00:00:00

  • Validation of cell-free culture using scanning electron microscopy (SEM) and gene expression studies.

    abstract：:A cell-free culture system for Cryptosporidium parvum was analysed using scanning electron microscopy (SEM) to characterise life cycle stages and compare gene expression in cell-free culture and cell culture using HCT-8 cells. Cryptosporidium parvum samples were harvested at 2 h, 8 h, 14 h, 26 h, 50 h, 74 h, 98 h, 122...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2015.03.002

    authors： Yang R,Elankumaran Y,Hijjawi N,Ryan U

    更新日期：2015-06-01 00:00:00

  • Caenorhabditis elegans and Panagrellus redivivus: enzyme-mediated modification of chemotaxis.

    abstract：:Treatment with mannosidase or sialidase completely inhibited chemotactic responses of Caenorhabditis elegans wild type, C. elegans mutants CB1377 (daf-6)X and CB1379 (che-3)I, and Panagrellus redivivus to a source of attractants. Trypsin (EC3.4.21.4) caused a partial reduction in the level of chemoresponse. Normal che...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/0014-4894(84)90044-4

    authors： Jansson HB,Jeyaprakash A,Damon RA Jr,Zuckerman BM

    更新日期：1984-12-01 00:00:00

  • Effects of Allium sativum on IFN-γ and IL4 concentrations in mice with cystic echinococcosis.

    abstract：:The aim of the current investigation was to assess the impacts of methanolic extract of Allium sativum (MEAS) on IL-4 (a cytokine derived from Th2 cells) and IFN-ɣ (a cytokine derived from Th1 cells) levels in mice infected with Echinococcus granulosus. Sixty healthy BALB/c female mice were used in this study. Each an...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2020.108042

    authors： Shirgholami Z,Borji H,Mohebalian H,Heidarpour M

    更新日期：2021-01-01 00:00:00

  • Regulation of immunity in Trypanosoma cruzi infection.

    abstract：:Immunity to T. cruzi is complex, involving among other components, antibody production, CD4+ helper cells, CD8+ T cells as both regulators and effectors of immunity, and possibly, double-negative T cells. In addition, several of these components have been implicated in pathogenesis in the chronic infection. Although t...

    journal_title：Experimental parasitology

    pub_type： 杂志文章,评审

    doi：10.1016/0014-4894(91)90013-m

    authors： Tarleton RL

    更新日期：1991-07-01 00:00:00

  • Expression profile and subcellular localization of HslV, the proteasome related protease from Trypanosoma cruzi.

    abstract：:Trypanosoma cruzi is a rare example of an eukaryote that has genes for two threonine proteases: HslVU complex and 20S proteasome. HslVU is an ATP-dependent protease consisting of two multimeric components: the HslU ATPase and the HslV peptidase. In this study, we expressed and obtained specific antibodies to HslU and ...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2011.10.011

    authors： Barboza NR,Cardoso J,de Paula Lima CV,Soares MJ,Gradia DF,Hangai NS,Bahia MT,de Lana M,Krieger MA,Guerra de Sá R

    更新日期：2012-02-01 00:00:00

  • Trypanosoma cruzi: peripheral blood monocytes and heart macrophages in the resistance to acute experimental infection in rats.

    abstract：:The contribution of mononuclear phagocytes to host resistance against acute Chagas disease has been studied in vivo in a rat model inoculated with Trypanosoma cruzi, Y strain. Acute T. cruzi infection triggered a dramatic increase (937%) in peripheral blood monocyte number at day 12 of infection. At this point, histol...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1006/expr.2000.4576

    authors： Melo RC,Machado CR

    更新日期：2001-01-01 00:00:00

  • Echinostoma caproni (Trematoda): differential in vivo cytokine responses in high and low compatible hosts.

    abstract：:In order to investigate the factors determining the expulsion of intestinal trematodes, we have analyzed the in vivo cytokine responses at several levels and the local responses against Echinostoma caproni (Trematoda) in two host species displaying different compatibility with the parasite. The response of the high co...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2010.09.004

    authors： Trelis M,Sotillo J,Monteagudo C,Fried B,Marcilla A,Esteban JG,Toledo R

    更新日期：2011-02-01 00:00:00

  • Toxoplasma gondii: evidence for interleukin-12-dependent and-independent pathways of interferon-gamma production induced by an attenuated parasite strain.

    abstract：:Immunity in mice infected with Toxoplasma gondii is dependent upon the ability to generate protective levels of the cytokine IFN-gamma. In this report, we present evidence that the attenuated vaccine strain, ts-4, induces the latter cytokine by both IL-12-dependent and -independent pathways. In contrast, strain ME49 a...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1006/expr.1996.0096

    authors： Scharton-Kersten T,Caspar P,Sher A,Denkers EY

    更新日期：1996-11-01 00:00:00

  • Plasmodium yoelii: contribution of oocysts melanization to natural refractoriness in Anopheles dirus.

    abstract：:It is well known that Anopheles dirus is naturally refractory to rodent malaria parasite, Plasmodium yoelii, but the mechanism is still largely unknown. Here, we found that some P. yoelii taken into An. dirus could develop into oocysts, but oocysts were partially melanized at 7 days and completely melanized at 15 days...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2007.02.013

    authors： Wen-Yue X,Jian Z,Tao-Li Z,Fu-Sheng H,Jian-Hua D,Ying W,Zhong-Wen Q,Li-Sha X

    更新日期：2007-08-01 00:00:00

  • Arg-265: a critical residue of L.donovani cytosolic SHMT in maintaining the binding of THF and catalysis.

    abstract：:Serine hydroxymethyltransferase belongs to the class of pyridoxal-5-phosphate enzymes along with aspartate aminotransferase. To explore the function of residue(s) involved in binding of the carboxylate group of Tetrahydrofolic acid (THF) to L. donovani cytosolic serine hydroxymethyltransferase (LdcSHMT), the gene was ...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2014.12.004

    authors： Gandhi S,Gaur N,Krishna S,Siddiqi MI,Saxena JK

    更新日期：2015-02-01 00:00:00

  • Haemonchus contortus: evaluation of two signal sequence trapping systems for detection of secreted molecules.

    abstract：:Given that signal sequences between secreted proteins of different species can be interchanged, it is reasonable to expect that both mammalian and yeast signal sequence trapping (SST) systems would secrete Haemonchus contortus proteins with similar efficiency and quality. To determine if H. contortus cDNAs that contai...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2007.12.017

    authors： Donald D,Chen Y,Hartman D,Zawadzki JL

    更新日期：2008-05-01 00:00:00

  • In vitro culture of the mosquito stages of Plasmodium falciparum.

    abstract：:The sporogonic cycle of Plasmodium falciparum was obtained in vitro. Mature gametocytes, from blood-stage cultures, produced gametes that underwent fertilization at elevated pH and ambient temperatures. Wheat germ agglutinin stimulated transformation of zygotes into retorts and ookinetes. Twenty-four hours thereafter,...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1006/expr.1993.1014

    authors： Warburg A,Schneider I

    更新日期：1993-03-01 00:00:00

  • Leishmania infantum: mixed T-helper-1/T-helper-2 immune response in experimentally infected BALB/c mice.

    abstract：:The main goal of the present study was to characterise the course of infection and immunological responses developed by Leishmania infantum infected BALB/c mice. Parasite load was determined by Real-time TaqMan PCR while cytokine and Immunoglobulin G (IgG) production were assessed by ELISA. Leishmania DNA was detected...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2006.09.013

    authors： Rolão N,Cortes S,Gomes-Pereira S,Campino L

    更新日期：2007-03-01 00:00:00

  • Schistosoma mansoni: peritoneal plasmacytogenesis and polypoid transformation of mesenteric milky spots in infected mice.

    abstract：:We have studied inflammatory reactions in the mesenteric tissue of mice infected with Schistosoma mansoni. Perivascular tissue contained diffuse infiltrates of macrophages, eosinophilic granulocytes and lymphocytes. Angiogenesis in the perivascular adipose tissue was associated with superficial plasmacytogenic foci. P...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/0014-4894(92)90203-m

    authors： Weinberg DF,Baldo-Correa E,Lenzi HL,Borojevic R

    更新日期：1992-06-01 00:00:00

  • Neospora caninum: comparative gene expression profiling of Neospora caninum wild type and a temperature sensitive clone.

    abstract：:To understand the genetic basis of virulence, gene expression profiles of a temperature-sensitive clone (NCts-8, relatively avirulent) and its wild type (NC-1) of Neospora caninum were characterized and compared using a high-density microarray with approximately 63,000 distinct oligonucleotides. This microarray consis...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2011.09.007

    authors： Li RW,Tuo W

    更新日期：2011-12-01 00:00:00

  • Plasmodium falciparum: the effect of pH and Ca2+ concentration on the in vitro cytoadherence of infected erythrocytes to amelanotic melanoma cells.

    abstract：:Cytoadherence of Plasmodium falciparum-infected erythrocytes to amelanotic melanoma cells was pH dependent; increased adherence was observed in the pH range of 6.1 to 6.8 and was greatest between pH 6.6 and 6.8 Ca2+ promoted cytoadherence, but at higher concentrations (40-50 mM) than is usually the case for cell-cell ...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/0014-4894(91)90108-9

    authors： Crandall I,Smith H,Sherman IW

    更新日期：1991-10-01 00:00:00

  • Peptidases of pinworms Syphacia muris and Passalurus ambiguus.

    abstract：:In this first report about pinworms peptidases we primarily characterize peptidases released during in vitro maintenance of two common pinworms of laboratory animals -Syphacia muris and Passalurus ambiguus. The peptidase activity obtained using sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) showe...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2010.04.018

    authors： Vadlejch J,Lytvynets A,Jankovská I,Langrová I

    更新日期：2010-10-01 00:00:00

  • Scanning electron microscopy of Haemonchus contortus exposed to tannin-rich plants under in vivo and in vitro conditions.

    abstract：:The structural changes induced in adult Haemonchus contortus after in vitro and in vivo contact with a tannin-rich (TR) plant, either tzalam (Lysiloma latisiliquum) or sainfoin (Onobrychis viciifolia), were assessed using scanning electron microscopy (SEM). All the worms used in the study were adult females. The Haemo...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2012.11.024

    authors： Martínez-Ortíz-de-Montellano C,Arroyo-López C,Fourquaux I,Torres-Acosta JF,Sandoval-Castro CA,Hoste H

    更新日期：2013-03-01 00:00:00

  • Trypanosoma brucei: two-dimensional gel analysis of the major glycosomal proteins during the life cycle.

    abstract：:Kinetoplastid organisms possess a unique organelle, the glycosome, which compartmentalizes the Embden-Meyerhof segment of glycolysis and several other metabolic pathways. In Trypanosoma brucei many of the enzyme activities localized to the glycosome are stage regulated. Two-dimensional gel analysis was used to examine...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/0014-4894(90)90109-p

    authors： Parsons M,Nielsen B

    更新日期：1990-04-01 00:00:00

  • Biochemical, immunological, and biological characterization of Trypanosoma cruzi populations of the Andean north of Chile.

    abstract：:Twenty-one Trypanosoma cruzi stocks isolated from Triatoma infestans and humans of the Chilean Andean highlands were studied at the genotypic level by schizodeme and molecular karyotype analyses, which allowed a clear distinction of the parasites from those hosts. A phenotypical characterization was performed by prote...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1006/expr.1995.1100

    authors： Gonzalez J,Muñoz S,Ortiz S,Anacona D,Salgado S,Galleguillos M,Neira I,Sagua H,Solari A

    更新日期：1995-08-01 00:00:00

  • Balamuthia and Acanthamoeba-binding antibodies in West African human sera.

    abstract：:Little is known about the prevalence of Balamuthia mandrillaris amoebae and Balamuthia amoebic encephalitis in Africa. As an approach, relative concentrations of amoebae-binding serum antibodies (Ab) were assessed by flow cytometry using formaldehyde-fixed B. mandrillaris, Acanthamoeba lenticulata 72-2 and Acanthamoeb...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2009.10.015

    authors： Kiderlen AF,Radam E,Schuster FL,Adjogoua EV,Akoua-Koffi C,Leendertz FH

    更新日期：2010-09-01 00:00:00

  • Molecular detection of Leishmania infection in sand flies in border line of Iran-Turkmenistan: restricted and permissive vectors.

    abstract：:A molecular study was carried out to incriminate sand fly vectors of cutaneous leishmaniasis (CL) in rural areas of Sarakhs district, Khorassane-Razavi Province, northeastern Iran, in 2011. Sand flies of Sergentomyia with three species and Phlebotomus with six species respectively comprised 73.3% and 26.7% of the spec...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2013.07.020

    authors： Bakhshi H,Oshaghi MA,Abai MR,Rassi Y,Akhavan AA,Sheikh Z,Mohtarami F,Saidi Z,Mirzajani H,Anjomruz M

    更新日期：2013-10-01 00:00:00

  • Nitazoxanide induces in vitro metabolic acidosis in Taenia crassiceps cysticerci.

    abstract：:Nitazoxanide (NTZ) is a broad-spectrum anti-parasitic drug used against a wide variety of protozoans and helminthes. Albendazole, its active metabolite albendazole sulfoxide (ABZSO), is one of the drugs of choice to treat both intestinal and tissue helminth and protozoan infections. However little is known regarding t...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2016.10.012

    authors： Isac E,de A Picanço G,da Costa TL,de Lima NF,de S M M Alves D,Fraga CM,de S Lino Junior R,Vinaud MC

    更新日期：2016-12-01 00:00:00

  • Anti-tick monoclonal antibody applied by artificial capillary feeding in Rhipicephalus (Boophilus) microplus females.

    abstract：:The tick Rhipicephalus microplus is an ectoparasite harmful to livestock, a vector of disease agents that affects meat and milk production. However, resistance to acaricides reflects the need for alternative tick control methods, among which vaccines have gained increasing relevance. In this scenario, monoclonal antib...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2012.02.006

    authors： Gonsioroski AV,Bezerra IA,Utiumi KU,Driemeier D,Farias SE,da Silva Vaz I Jr,Masuda A

    更新日期：2012-04-01 00:00:00

  • Synthesis, antimalarial activity and molecular docking of hybrid 4-aminoquinoline-1,3,5-triazine derivatives.

    abstract：:A series of novel hybrid 4-aminoquinoline 1,3,5-triazine derivatives was synthesized in a five-steps reaction and evaluated for their in vitro antimalarial activity against chloroquine-sensitive (3D7) and chloroquine-resistant (RKL-2) strains of Plasmodium falciparum. Entire synthetic derivatives showed higher antimal...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2015.06.016

    authors： Bhat HR,Singh UP,Thakur A,Kumar Ghosh S,Gogoi K,Prakash A,Singh RK

    更新日期：2015-10-01 00:00:00

  • Toxoplasma gondii: cloning, expression and immunoreactivity of recombinant ROP5 and ROP18 antigens.

    abstract：:Early diagnosis and determining the infective stage are critical for effective therapy of toxoplasmosis. Owing to the progress in biotechnology, commonly used native, non-standardized diagnostic antigens should be replaced by genetically engineered antigens. The recombinant proteins are also promising components of su...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2015.01.006

    authors： Grzybowski MM,Dziadek B,Dziadek J,Gatkowska J,Dzitko K,Długońska H

    更新日期：2015-03-01 00:00:00

  • Sex dichotomy in the course of experimental latent toxoplasmosis.

    abstract：:Toxoplasma gondii is an opportunistic zoonotic protozoan that exceeds neurological and congenital impact sequence to reactivating latent toxoplasmosis especially under immunosuppression. Sex-associated hormones influence the severity of Toxoplasma infection. Thus, our study aimed to compare toxoplasmosis associated mo...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2019.05.003

    authors： Hegazy MM,Elmehankar MS,Azab MS,El-Tantawy NL,Abdel-Aziz A

    更新日期：2019-07-01 00:00:00