Peptidases of pinworms Syphacia muris and Passalurus ambiguus.

Abstract:

:In this first report about pinworms peptidases we primarily characterize peptidases released during in vitro maintenance of two common pinworms of laboratory animals -Syphacia muris and Passalurus ambiguus. The peptidase activity obtained using sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) showed the presence of peptidases from S. muris with a wide range of molecular size (25-110 kDa), which degrades gelatin and mucin at alkaline pH levels. P. ambiguus released serine and aspartyl peptidases degrading gelatin at all tested pH (3, 5, 7, and 9) and at acidic pH Passalurus released aspartyl and cysteine peptidases which are active against mucin.

journal_name

Exp Parasitol

authors

Vadlejch J,Lytvynets A,Jankovská I,Langrová I

doi

10.1016/j.exppara.2010.04.018

subject

Has Abstract

pub_date

2010-10-01 00:00:00

pages

156-60

issue

2

eissn

0014-4894

issn

1090-2449

pii

S0014-4894(10)00135-9

journal_volume

126

pub_type

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