Leishmania: genus identification based on a specific sequence of the 18S ribosomal RNA sequence.

abstract：:Giardia lamblia is a parasite that causes giardiasis in humans and other mammals. The common treatment includes different classes of drugs, which were described to produce unpleasant side effects. Mentha x piperita, popularly known as peppermint, is a plant that is frequently used in the popular medicine to treat gast...

journal_title：Experimental parasitology

authors： Vidal F,Vidal JC,Gadelha AP,Lopes CS,Coelho MG,Monteiro-Leal LH

更新日期：2007-01-01 00:00:00

abstract：:A mode of action of the inducible treatment with trypsin for the development of Mesocestoides lineatus tetrathyridium to adult was analyzed by administering various agents effective on Ca2+-dependent metabolic pathways in the cells: protein kinase C activators such as a synthetic diacylglycerol, 1-oleoyl-2-acetylglyce...

journal_title：Experimental parasitology

authors： Kawamoto F,Fujioka H,Kumada N,Kojima K

更新日期：1986-12-01 00:00:00

abstract：:The expression and activity of topoisomerase I (PfTopoI) has been examined during the intraerythrocytic stages of the Plasmodium falciparum life cycle. The promoter is inactive during the early ring stage and becomes active only during the later trophozoite and schizont stages. The PfTOP1 transcript starts to accumula...

journal_title：Experimental parasitology

authors： Tosh K,Cheesman S,Horrocks P,Kilbey B

更新日期：1999-02-01 00:00:00

abstract：:An NADP-linked glutamate dehydrogenase (EC 1.4.1.4) was found in the soluble fraction of Trichomonas vaginalis. Its molecular weight was about 230,000 (gel filtration). The enzyme, partially purified by diafiltration and hydroxyapatite column chromatography, was heat stable (1 hr at 57 C). It catalyzed both the aminat...

journal_title：Experimental parasitology

authors： Turner AC,Lushbaugh WB

更新日期：1988-10-01 00:00:00

abstract：:Giardia lamblia is a protozoan pathogen with distinct cytoskeletal structures, including median bodies and eight flagella. In this study, we examined components comprising G. lamblia flagella. Crude flagellar extracts were prepared from G. lamblia trophozoites, and analyzed by two-dimensional (2-D) gel electrophoresis...

journal_title：Experimental parasitology

authors： Kim J,Lee HY,Lee MA,Yong TS,Lee KH,Park SJ

更新日期：2013-10-01 00:00:00

abstract：:In murine Schistosoma mansoni infections, fewer adult worms develop in male than in female mice infected with the same number of cercariae. To evaluate a potential role for testosterone in this phenomenon, testosterone levels were manipulated in groups of CBA/J mice that were then infected and monitored for survival r...

journal_title：Experimental parasitology

authors： Nakazawa M,Fantappie MR,Freeman GL Jr,Eloi-Santos S,Olsen NJ,Kovacs WJ,Secor WE,Colley DG

更新日期：1997-03-01 00:00:00

abstract：:An efficient technique was developed for separating early and late stages of embryonic development in eggs of Heterodera glycines. This technique takes advantage of density changes that occur during embryogenesis in the developing embryo and egg to partition the egg within a sucrose step gradient. Sorted samples of eg...

journal_title：Experimental parasitology

authors： Burgwyn B,Cook RL,Bolla RI

更新日期：2003-11-01 00:00:00

abstract：:Toxoplasma gondii is an ubiquitous intracellular parasite, causative agent of toxoplasmosis, and a worldwide zoonosis for which an effective vaccine is needed. A group of proteins secreted by tachyzoites during host-cell invasion was isolated from the interaction medium. It induced the permeability of the cells as ass...

journal_title：Experimental parasitology

authors： Azzouz S,Maache M,Osuna A,Lawton P,Pétavy AF

更新日期：2012-01-01 00:00:00

abstract：:Trypanosoma musculi is a hemoflagellate parasite producing a characteristic course of infection in the mouse, terminating in elimination of the parasite from the vascular system with permanent immunity to reinfection. While this elimination is known to require functional T lymphocytes, the role of these cells has rema...

journal_title：Experimental parasitology

authors： House RV,Dean JH

更新日期：1988-10-01 00:00:00

abstract：:The tegumental alterations in adult Fasciola hepatica induced by the experimental fasciolide OZ78 were investigated utilizing scanning electron microscopy (SEM). Twelve weeks post-infection with F. hepatica, rats were treated with a single 100mg/kg oral dose of OZ78 and flukes were recovered from the bile ducts after ...

journal_title：Experimental parasitology

authors： Keiser J,Morson G

更新日期：2008-05-01 00:00:00

abstract：:Experimental infections of chimpanzees with Onchocerca volvulus and cattle with Onchocerca ochengi provide model systems for research in human onchocerciasis. These infections share many similarities from the standpoint of parasite biology, but little is known about the comparability of immune responses in the two sys...

journal_title：Experimental parasitology

authors： Graham SP,Lustigman S,Trees AJ,Bianco AE

更新日期：2000-03-01 00:00:00

abstract：:A drug-resistant Trypanosoma congolense strain with predetermined curative doses (CD50 and CD90) of samorin at 13.9 +/- 1.02 and 20.3 +/- 1.13 mg/kg body weight, respectively, was cyclically transmitted through tsetse flies and by syringe passages in mice in the absence of drug pressure. The changing levels of drug se...

journal_title：Experimental parasitology

authors： Nyeko JH,Golder TK,Otieno LH,Ssenyonga GS

更新日期：1989-11-01 00:00:00

abstract：:Leishmaniasis, a neglected tropical disease (NTD) causes major health problems in the tropical and subtropical world. Most of the antileishmanial modern therapies with different formulations of pentavalent antimonials, Miltefosine, Amphotericin B etc. are not satisfactory in recent times due to high toxicity to the ho...

journal_title：Experimental parasitology

authors： Paik D,Das P,De T,Chakraborti T

更新日期：2014-11-01 00:00:00

abstract：:Aspartic proteases are important virulence factors for pathogens and are recognized as attractive drug targets. Seven aspartic proteases (ASPs) have been identified in Toxoplasma gondii genome. Bioinformatics and phylogenetic analyses regroup them into five monophyletic groups. Among them, TgASP1, a coccidian specific...

journal_title：Experimental parasitology

authors： Polonais V,Shea M,Soldati-Favre D

更新日期：2011-08-01 00:00:00

abstract：:Here we describe the cloning and characterization of the Schistosoma mansoni Alkaline Phosphatase (SmAP), previously identified in the tegument of adult worms. SmAP encodes a complete sequence composed of 536 amino acids containing an N-terminal signal peptide, five N-glycosylation sites, and a GPI anchor signal, simi...

journal_title：Experimental parasitology

authors： Araujo-Montoya BO,Rofatto HK,Tararam CA,Farias LP,Oliveira KC,Verjovski-Almeida S,Wilson RA,Leite LC

更新日期：2011-11-01 00:00:00

abstract：:This is the first report establishing the existence of glycolipids synthesized by plasmodia, in particular Plasmodium falciparum. Trophozoites, schizonts, gametocytes, and gametes were metabolically labeled in vitro with [3H]glucosamine, [3H]galactose, [3H]glucose, [3H]mannose, [3H]fucose, [32P]inorganic phosphate, or...

journal_title：Experimental parasitology

authors： Sherwood JA,Spitalnik SL,Aley SB,Quakyi IA,Howard RJ

更新日期：1986-08-01 00:00:00

abstract：:There is no evidence that Hymenolepis diminuta can carry out sulphoconjugation reactions. Neither whole worms nor worm extracts were able to sulphate 4-methylumbelliferone. No sulphotransferase activity could be demonstrated in H. diminuta using a variety of substrates, nor was H. diminuta capable of synthesising the ...

journal_title：Experimental parasitology

authors： Raines PS,Barrett J

更新日期：1988-04-01 00:00:00

abstract：:In this report, an immunodominant antigen called BgIRA from Babesia gibsoni is identified and described. A highly repetitive antigen was screened from a cDNA library. The genomic BgIRA gene exists as single cope gene and contains 10 introns. BgIRA plays a dominant role in the immune response in dogs infected with B. g...

journal_title：Experimental parasitology

authors： Jia H,Terkawi MA,Aboge GO,Goo YK,Zhou J,Lee EG,Nishikawa Y,Igarashi I,Fujisaki K,Xuan X

更新日期：2008-01-01 00:00:00

abstract：:Genetic cross is a powerful tool for studying malaria genes contributing to drug resistance, parasite development, and pathogenesis. Cloning and identification of recombinant progeny (RP) is laborious and expensive, especially when a large proportion of progeny derived from self-fertilization are present in the unclon...

journal_title：Experimental parasitology

authors： Qi Y,Zhu F,Li J,Fu Y,Pattaradilokrat S,Hong L,Liu S,Huang F,Xu W,Su XZ

更新日期：2013-01-01 00:00:00

abstract：:Three studies were conducted to examine the function of ecdysteroids in the development of parasitic nematodes. Ecdysone and 20-hydroxyecdysone were extracted, separated chromatographically, and measured in the reproductive tracts of adult female Ascaris suum. Perienteric fluid and the body wall did not contain measur...

journal_title：Experimental parasitology

authors： Fleming MW

更新日期：1985-10-01 00:00:00

abstract：:In this work CD4-knockout mice were used as a model to analyse the role of CD4+ T cells in the antibody response against Echinococcus granulosus immunization or experimental infection. Results obtained with mice immunized with protoscolex antigens indicated that these contain T-independent antigens. After infection, C...

journal_title：Experimental parasitology

authors： Baz A,Carol H,Fernández V,Mourglia-Ettlin G,Nieto A,Orn A,Dematteis S

更新日期：2008-08-01 00:00:00

abstract：:The in vitro growth of Plasmodium falciparum was reduced by 35 and 43% through high concentrations (5 mmole/liter) of magnesium in RPMI medium and magnesium-free medium, respectively, after 48 hr, whereas no significant inhibition could be observed under these conditions after 24 hr cultivation in the respective mediu...

journal_title：Experimental parasitology

authors： Hess FI,Kilian A,Söllner W,Nothdurft HD,Pröll S,Löscher T

更新日期：1995-03-01 00:00:00

abstract：:Living Leishmania amazonensis amastigotes were incubated with radioiodinated N-benzyloxycarbonyl-L-tyrosyl-L-alanyl diazomethane (Z-Tyr-AlaCHN2), an irreversible inhibitor of mammalian cathepsins B and L. Parasite lysates were subjected to electrophoresis in gelatin-containing sodium dodecyl sulfate-acrylamide gels to...

journal_title：Experimental parasitology

authors： Alfieri SC,Pral EM,Shaw E,Ramazeilles C,Rabinovitch M

更新日期：1991-11-01 00:00:00

abstract：:Three-day-old specific-pathogen-free chickens were subcutaneously immunized with Eimeria tenella recombinant 5401 antigen (100 microg per chicken) with (0.25, 0.5 or 1.0mg per dose) or without ginsenosides, and boosted with the same dosage 14 days later. The chickens were challenged with 6 x 10(4) homologous sporulate...

journal_title：Experimental parasitology

authors： Du A,Hu S,Wang S

更新日期：2005-11-01 00:00:00

abstract：:Parasitic castration in the snail-trematode relationship can be understood as any change in the reproductive function of the snail that is due to interference by the developing larvae inside the snail that leads to the reduction or complete disruption of egg-laying activity. This study was designed to observe the para...

journal_title：Experimental parasitology

authors： Faro MJ,Perazzini M,Corrêa Ldos R,Mello-Silva CC,Pinheiro J,Mota EM,de Souza S,de Andrade Z,Júnior AM

更新日期：2013-06-01 00:00:00

abstract：:Fasciola hepatica is a digenean trematode which infects a wide variety of domestic animals and also humans. Previous studies have demonstrated that four monoclonal antibodies (Mabs) against the total extract of F. hepatica redia (named as 1E4, 6G11, 4E5 and 4G11) also recognized the excretion - secretion antigens (ES ...

journal_title：Experimental parasitology

authors： Alba A,Sánchez J,Hernández H,Mosqueda M,Rodríguez SY,Capó V,Otero O,Alfonso C,Marcet R,Sarracent J

更新日期：2016-09-01 00:00:00

abstract：:A Real-time quantitative PCR assay to quantify the Toxoplasma gondii apicoplast was studied. Primers were designed to amplify a 305bp product specific to T. gondii apicoplast. Standard curves were generated for both T. gondii apicoplast DNA and genomic DNA, and were used to compute the relative concentration of apicop...

journal_title：Experimental parasitology

authors： Wu L,Chen SX,Jiang XG,Cao JP

更新日期：2009-12-01 00:00:00

abstract：:Antimony unresponsiveness in mucocutaneous and visceral leishmaniasis is a serious clinical problem. Information on the mechanisms and characteristics of drug resistance in parasites that suggest chemotherapeutic strategies to overcome resistance is of practical importance. We developed nine lines of Leishmania resist...

journal_title：Experimental parasitology

authors： Grögl M,Oduola AM,Cordero LD,Kyle DE

更新日期：1989-07-01 00:00:00

abstract：:Toxoplasma gondii is the etiologic agent of toxoplasmosis. Although the combination of sulfadiazine and pyrimethamine is used as therapy for this disease, these drugs can have serious side effects and its use is limited in pregnancy. Therefore there is a need for new anti-T. gondii drugs in the clinic. Some systems fo...

journal_title：Experimental parasitology

authors： Jin C,Kaewintajuk K,Jiang J,Jeong W,Kamata M,Kim HS,Wataya Y,Park H

更新日期：2009-02-01 00:00:00

abstract：:This study investigated the genetic characteristics of Toxoplasma gondii samples collected from 62 patients with toxoplasmosis in Sao Paulo State, Brazil. DNA samples were isolated from blood, cerebrospinal fluid and amniotic fluids of 25 patients with cerebral toxoplasmosis and AIDS, two patients with acute toxoplasm...

journal_title：Experimental parasitology

authors： Ferreira IM,Vidal JE,de Mattos Cde C,de Mattos LC,Qu D,Su C,Pereira-Chioccola VL

更新日期：2011-10-01 00:00:00