Nippostrongylus brasiliensis: infection decreases plasma butyrylcholinesterase activity in rats.

Abstract:

:Plasma butyrylcholinesterase (BChE) hydrolyzes ester-containing compounds such as succinylcholine, as well as acting as a scavenger against neurotoxic organophosphates (OPs). We previously found that Nippostrongylus brasiliensis infection makes rats more susceptible to OP toxicity by decreasing serum paraoxonase-1 (PON1) activity. In the present study, we examined the effects of N.brasiliensis infection on acetylcholinesterase (AChE) activity in plasma, red blood cells (RBCs), brain and diaphragm, as well as serum PON1 activity, in rats at day 7 after infection. N.brasiliensis infection significantly decreased plasma BChE and PON1 activities without significantly altering AChE activity in RBCs, brain and diaphragm. These results provide further insight into the unusual deleterious effects of intestinal nematode infections on body homeostasis.

journal_name

Exp Parasitol

authors

Farid AS,Horii Y

doi

10.1016/j.exppara.2009.02.009

subject

Has Abstract

pub_date

2009-06-01 00:00:00

pages

162-4

issue

2

eissn

0014-4894

issn

1090-2449

pii

S0014-4894(09)00044-7

journal_volume

122

pub_type

杂志文章
  • Caenorhabditis elegans and Panagrellus redivivus: enzyme-mediated modification of chemotaxis.

    abstract::Treatment with mannosidase or sialidase completely inhibited chemotactic responses of Caenorhabditis elegans wild type, C. elegans mutants CB1377 (daf-6)X and CB1379 (che-3)I, and Panagrellus redivivus to a source of attractants. Trypsin (EC3.4.21.4) caused a partial reduction in the level of chemoresponse. Normal che...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/0014-4894(84)90044-4

    authors: Jansson HB,Jeyaprakash A,Damon RA Jr,Zuckerman BM

    更新日期:1984-12-01 00:00:00

  • The potential therapeutic effect of adipose-derived mesenchymal stem cells in the treatment of cutaneous leishmaniasis caused by L. major in BALB/c mice.

    abstract::Leishmaniasis is one of the most neglected tropical infectious diseases in the world. The emergence of drug resistance and toxicity and the high cost of the available drugs with a lack of new anti-leishmanial drugs highlight the need to search for newer therapies with anti-leishmanial activities. Due to the mesenchyma...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2020.108063

    authors: Bahrami S,Safari M,Razi Jalali MH,Ghorbanpoor M,Tabandeh MR,Rezaie A

    更新日期:2021-01-04 00:00:00

  • Molecular cloning and characterization of leucine aminopeptidase from Fasciola gigantica.

    abstract::M17 leucine aminopeptidase (LAP) is one of a family of metalloexopeptidases, of which short peptide fragments are cleaved from the N-terminals. In this study, the full length of cDNA encoding Fasciola gigantica LAP (FgLAP) was cloned from adult parasites. The amino acid sequences of FgLAP showed a high degree of ident...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2012.04.008

    authors: Changklungmoa N,Chaithirayanon K,Kueakhai P,Meemon K,Riengrojpitak S,Sobhon P

    更新日期:2012-07-01 00:00:00

  • Schistosoma mansoni: cholesterol uptake by paired and unpaired worms.

    abstract::Mature males and females of Schistosoma mansoni were incubated for 24 hr in medium containing [3H]cholesterol. Worms thus labeled were paired for 24 hr with unlabeled partners, in vitro or in vivo by surgical implantation into hamsters. Controls consisted of additional unlabeled worms that did not pair. Scintillation ...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/0014-4894(86)90189-x

    authors: Popiel I,Basch PF

    更新日期:1986-06-01 00:00:00

  • Amblyomma americanum: physiochemical isolation of a protein derived from the tick salivary gland that is capable of inducing immune resistance in guinea pigs.

    abstract::Crude salivary gland derived proteins from Amblyomma americanum ticks were analyzed by physiochemical (gel filtration and ion exchange chromatography) and immunochemical guinea pig IgG1 (anti-tick immunoaffinity column) techniques for the presence of antigens responsible for the induction of host immune resistance res...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/0014-4894(86)90006-8

    authors: Brown SJ,Askenase PW

    更新日期:1986-08-01 00:00:00

  • Intranasal immunization with recombinant Trichinella spiralis serine protease elicits protective immunity in BALB/c mice.

    abstract::The aim of this study was to observe the intestinal mucosal/systemic responses triggered by intranasal vaccination using recombinant Trichinella spiralis serine protease (rTsSP) and its capacity to elicit immune protection against larva challenge in a murine model. rTsSP coupled with cholera toxin B subunit (CTB) was ...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2019.04.006

    authors: Sun GG,Lei JJ,Ren HN,Zhang Y,Guo KX,Long SR,Liu RD,Jiang P,Wang ZQ,Cui J

    更新日期:2019-06-01 00:00:00

  • Plasmodium falciparum: allelic variation in the merozoite surface protein 1 gene in wild isolates from southern Vietnam.

    abstract::Allelic variation in the Plasmodium falciparum merozoite surface protein 1 (MSP1) gene is expressed as an association of allelic types in variable blocks. In this study, a PCR strategy that can detect 24 different MSP1 association types was used to investigate allelic variation in the MSP1 gene. We identified 236 dist...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1997.4147

    authors: Kaneko O,Kimura M,Kawamoto F,Ferreira MU,Tanabe K

    更新日期:1997-05-01 00:00:00

  • Flow cytometric screening for anti-leishmanials in a human macrophage cell line.

    abstract::High-throughput drug screening methods against the intracellular stage of Leishmania have been facilitated by the development of in vitro models of infection. The use of cell lines rather than primary cells facilitates these methods. Peripheral blood mononuclear cell (PBMC) derived macrophages and THP-1 cells were inf...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2010.06.007

    authors: Mehta SR,Zhang XQ,Badaro R,Spina C,Day J,Chang KP,Schooley RT

    更新日期:2010-12-01 00:00:00

  • Screening and characterization of apical membrane antigen 1 interacting proteins in Eimeria tenella.

    abstract::Avian coccidiosis is a widespread and economically significant disease of poultry. It is an enteric disease caused by several protozoan Eimeria species. Eimeria belongs to the phylum Apicomplexa, which exhibits an unusual mechanism of host cell invasion. During invasion of host cells, the protein apical membrane antig...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2016.09.014

    authors: Han H,Xue P,Dong H,Zhu S,Zhao Q,Huang B

    更新日期:2016-11-01 00:00:00

  • Giardia lamblia: evaluation of the in vitro effects of nocodazole and colchicine on trophozoites.

    abstract::Giardia lamblia is the most commonly detected parasite in the intestinal tract of humans and other mammals causing giardiasis. Giardia presents several cytoskeletal structures with microtubules as major components such as the ventral adhesive disk, eight flagella axonemes, the median body and funis. Many drugs have al...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2005.01.007

    authors: Mariante RM,Vancini RG,Melo AL,Benchimol M

    更新日期:2005-05-01 00:00:00

  • Brugia pahangi: production of a monoclonal antibody reactive with the surface of infective larvae.

    abstract::Monoclonal antibodies against infective third-stage larvae (L3) of Brugia pahangi were generated from mice immunized with L3 antigens. The monoclonal antibodies were L3 stage-specific or stage-nonspecific. A BpG1 monoclonal antibody (IgG1 subclass) showing L3 stage-specificity was examined in detail. BpG1 recognized t...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/0014-4894(92)90130-3

    authors: Oikawa Y,Ikeda T,Horii Y,Fujita K,Tsukidate S

    更新日期:1992-08-01 00:00:00

  • Schistosoma mansoni: modulation of hemocyte surface polypeptides detected in individual snails, Biomphalaria glabrata, following larval exposure.

    abstract::As an approach to better understand the molecular mechanisms underlying the differential cellular response to larval Schistosoma mansoni observed in Biomphalaria glabrata, we have analyzed hemocyte membrane-associated polypeptides from inbred susceptible and resistant strains of B. glabrata. A combination of technique...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1994.1053

    authors: Coustau C,Yoshino TP

    更新日期:1994-08-01 00:00:00

  • The effect of viroid infection of citrus trees on the amoebicidal activity of 'Maltese half-blood' (Citrus sinensis) against trophozoite stage of Acanthamoeba castellanii Neff.

    abstract::In order to promote a local Tunisian product, this study was designed to examine, for the first time, the anti-Acanthamoeba activity (Acanthamoeba castellanii Neff) of the essential oils of Tunisian Citrus sinensis peels (Maltese half-blood) and the effect of viroid plant infection on this activity. To do so, three sa...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2017.09.006

    authors: Zouaghi G,Najar A,Chiboub O,Sifaoui I,Abderrabba M,Lorenzo Morales J

    更新日期:2017-12-01 00:00:00

  • Trypanosoma brucei brucei, T. brucei gambiense, and T. brucei rhodesiense: common glycoproteins and glycoprotein oligosaccharide heterogeneity identified by lectin affinity blotting and endoglycosidase H treatment.

    abstract::Whole cell extracts of 10 clones of bloodstream forms of African trypanosomes representing two strains of Trypanosoma brucei gambiense, one strain of T. b. rhodesiense and one strain of T. b. brucei were fractionated on sodium dodecyl sulfate-polyacrylamide gels, electrophoretically transferred to nitrocellulose paper...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/0014-4894(87)90075-0

    authors: Frommel TO,Balber AE

    更新日期:1987-02-01 00:00:00

  • Giardia lamblia: the roles of bile, lactic acid, and pH in the completion of the life cycle in vitro.

    abstract::Large numbers (10(4) to greater than 10(5)/ml) of Type I water-resistant Giardia lamblia cysts were produced in vitro under conditions that are characteristic of the human intestinal lumen. We define Type I cyst morphology as oval shaped, smooth, and refractile, with cyst wall, axostyle, and median body visible in rel...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/0014-4894(89)90185-9

    authors: Gillin FD,Boucher SE,Rossi SS,Reiner DS

    更新日期:1989-08-01 00:00:00

  • Persistent production of inflammatory and anti-inflammatory cytokines and associated MHC and adhesion molecule expression at the site of infection and disease in experimental Trypanosoma cruzi infections.

    abstract::Trypanosoma cruzi infection in humans and experimental animals often results in a chronic heart and gut inflammation and a dysfunction known as Chagas' disease. Previous studies have shown that the cellular infiltrate in the hearts of animals with chronic Chagas' disease consists mainly of CD8+ T cells. In this study,...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1996.0106

    authors: Zhang L,Tarleton RL

    更新日期:1996-11-01 00:00:00

  • Leishmania braziliensis: localization of glycoproteins in promastigotes.

    abstract::Two species of glycoproteins from Leishmania braziliensis promastigotes of apparent molecular weights of 53,000 (glycoprotein 53) and 47,000 (glycoprotein 47) were localized. Four lectins with different sugar specificities bound to the blotting sheet to which the electrophoretically separated materials were transferre...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/0014-4894(86)90188-8

    authors: Nagakura K,Tachibana H,Kaneda Y,Nakae T

    更新日期:1986-06-01 00:00:00

  • Plasmodium berghei: partial purification and characterization of the mitochondrial cytochrome c oxidase.

    abstract::Mitochondria from a rodent malarial parasite (Plasmodium berghei) were successfully purified by differential centrifugation and 22% Percoll density gradient separation. The purified mitochondria from the erythrocytic stages of the parasite had a density of 1.05 and were found to be heterogeneous by transmission electr...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1993.1070

    authors: Krungkrai J,Krungkrai SR,Bhumiratana A

    更新日期:1993-09-01 00:00:00

  • Entamoeba histolytica: biochemical and molecular insights into the activities within microsomal fractions.

    abstract::One of the most fascinating aspects of the Entamoeba histolytica trophozoite ultrastructure is the lack of a typical secretory pathway, particularly of rough endoplasmic reticulum and Golgi system, in a cell with such a high secretory activity. Here, we describe the isolation of amoeba cell structures containing ER-ty...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2005.04.002

    authors: Salgado M,Villagómez-Castro JC,Rocha-Rodríguez R,Sabanero-López M,Ramos MA,Alagón A,López-Romero E,Sánchez-López R

    更新日期:2005-08-01 00:00:00

  • Effects of age and splenectomy on heavy infection of Angiostrongylus cantonensis in rats.

    abstract::This study was designed to determine the effects of age and the role of spleen in rats with heavy Angiostrongylus cantonensis infection. Young rats (8 weeks) infected with 100 larvae were found to have significantly higher worm recovery rate (75.0±6.6%) than the adult (6 months) (55.7±1.5%) and the aging ones (13 mont...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2012.04.004

    authors: Wang LC,Yen CM,Liu CL,Chen ER,Chao D

    更新日期:2012-06-01 00:00:00

  • Plasmodium falciparum: naturally occurring rabbit immunoglobulins recognize human band 3 peptide motifs and malaria-infected red cells.

    abstract::The reactivity to overlapping decapeptides based on sequences of human band 3 protein was determined for 24 rabbit serum samples. A high percentage of the sera recognized sequences of amino acid 650-670, as well as several other sequences representing putative exofacial regions of the band 3 protein. When sera were us...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1996.0006

    authors: Crandall I,Guthrie N,Sherman IW

    更新日期:1996-01-01 00:00:00

  • Prodigiosin is not a determinant factor in lysis of Leishmania (Viannia) braziliensis after interaction with Serratia marcescens D-mannose sensitive fimbriae.

    abstract::In this paper, the lytic activity of two variants of Serratia marcescens against promastigotes of Leishmania braziliensis was studied. In vitro assays showed that S. marcescens variant SM365 lyses L. braziliensis promastigotes, while the variant DB11 did not. Scanning electron microscopy (SEM) revealed that S. marcesc...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2009.03.004

    authors: Moraes CS,Seabra SH,Albuquerque-Cunha JM,Castro DP,Genta FA,de Souza W,Brazil RP,Garcia ES,Azambuja P

    更新日期:2009-06-01 00:00:00

  • The influence of natural rubber/Au nanoparticle membranes on the physiology of Leishmania brasiliensis.

    abstract::The development of nanotechnology has generated new means of disease diagnosis and treatment. Infectious diseases, including leishmaniasis, malaria, etc., have benefited from the advent of new nanomaterials and/or nanodevices capable of detecting specific antigens and antibodies with high specificity and low cost. In ...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2011.10.015

    authors: Barboza-Filho CG,Cabrera FC,Dos Santos RJ,De Saja Saez JA,Job AE

    更新日期:2012-02-01 00:00:00

  • Trypanosoma cruzi: parasite-induced release of lysosomal enzymes by human polymorphonuclear leukocytes.

    abstract::The release of beta-glucuronidase and lysozyme from human polymorphonuclear leukocytes (PMN) engaged in phagocytosis and lysis of Trypanosoma cruzi epimastigotes was studied in the presence or absence of chagasic serum. Lysosomal enzyme release was enhanced when parasites were sensitized with serum from a chronic Chag...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/0014-4894(83)90069-3

    authors: de Titto EH,Cardoni RL

    更新日期:1983-10-01 00:00:00

  • Schistosoma: rate of glucose import is altered by acetylcholine interaction with tegumental acetylcholine receptors and acetylcholinesterase.

    abstract::The blood dwelling stages of schistosomes have acetylcholinesterase (AChE) and nicotinic-like acetylcholine receptors (nAChR) on their teguments. Both AChE and nAChR are concentrated on the dorsal surface of the adult male, a major surface for nutrient uptake for the worm pair. Exposure of tegumental AChE and nAChR to...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1995.1152

    authors: Camacho M,Agnew A

    更新日期:1995-12-01 00:00:00

  • Schistosoma mansoni: control of extramedullar eosinophil myelopoiesis in chronically infected mice by inflammatory macrophages.

    abstract::Extramedullar proliferation of eosinophil granulocytes can be induced in mice chronically infected with Schistosoma mansoni, by intraperitoneal implants of glass coverslips. Immature eosinophils are located in discrete foci on glass implants; they are not correlated with the eosinophil population of the peritoneal cav...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/0014-4894(86)90041-x

    authors: Borojevic R,Cury El-Cheikh MC,Nicola MH

    更新日期:1986-12-01 00:00:00

  • Hymenolepis citelli (Cestoda) and Nematospiroides dubius (Nematoda): interspecific interaction in mice.

    abstract::In mice concurrently infected with Hymenolepis citelli and Nematospiroides dubius, survival of the tapeworm was prolonged, and there was an impairment of the efferent arm of the response to the cestode. The immunological rejection of a six cysticercoid primary H. citelli infection was delayed by the N. dubius infectio...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/0014-4894(85)90043-8

    authors: Alghali ST,Hagan P,Robinson M

    更新日期:1985-12-01 00:00:00

  • Toxoplasma gondii: the role of IFN-gamma, TNFRp55 and iNOS in inflammatory changes during infection.

    abstract::In order to examine the role of IFN-gamma, TNFRp55 and iNOS in inflammatory reaction during toxoplasmosis, IFN-gamma(-/-), TNFRp55(-/-) and iNOS(-/-) mice were experimentally infected with Toxoplasma gondii ME-49 strain. The organs of the mice were evaluated for histology and immunohistochemistry in detection of tissu...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2009.05.011

    authors: Silva NM,Vieira JC,Carneiro CM,Tafuri WL

    更新日期:2009-09-01 00:00:00

  • Leishmania major and Leishmania tropica: II. Effect of an immunomodulator, S(2) complex on the enzymes of the parasites.

    abstract::S(2) complex has been reported to have a direct antileishmanial effect. The possibility that the direct antileishmanial effect may be due to inhibition of key enzymes involved in glucose metabolism and/ or enzymes associated with virulence was investigated. Cell pellets were prepared from cultures of both axenic amast...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2005.09.006

    authors: Al-Mulla Hummadi YM,Al-Bashir NM,Najim RA

    更新日期:2006-02-01 00:00:00

  • Hymenolepis diminuta: analysis of the expression of Toll-like receptor genes (TLR2 and TLR4) in the small and large intestines of rats.

    abstract::Toll receptors play a critical role in the rapid activation of innate immune responses to a variety of pathogens. In mammals, Toll-like receptors (TLR) have been found in both immune related cells and other cells. At present little is known about the participation of TLR in host defense mechanisms during parasitic inf...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2011.12.002

    authors: Kosik-Bogacka DI,Wojtkowiak-Giera A,Kolasa A,Salamatin R,Jagodzinski PP,Wandurska-Nowak E

    更新日期:2012-03-01 00:00:00