Plasmodium falciparum: naturally occurring rabbit immunoglobulins recognize human band 3 peptide motifs and malaria-infected red cells.


:The reactivity to overlapping decapeptides based on sequences of human band 3 protein was determined for 24 rabbit serum samples. A high percentage of the sera recognized sequences of amino acid 650-670, as well as several other sequences representing putative exofacial regions of the band 3 protein. When sera were used to stain immunofluorescently human erythrocytes, some of which were infected with P. falciparum, those samples that predominantly reacted with amino acids 650-670 stained P. falciparum-infected red cells, whereas those that reacted with other regions of band 3 stained all erythrocytes. A positive correlation was found between anti-band 3 reactivity and the capacity of a serum to inhibit the cytoadherence of P. falciparum-infected erythrocytes to C32 amelanotic melanoma cells. Also, some rabbit sera immunoprecipitated a high-molecular-weight protein from extracts of surface iodinated P. falciparum-infected red cells.


Exp Parasitol


Crandall I,Guthrie N,Sherman IW




Has Abstract


1996-01-01 00:00:00














  • Chryseobacterium indologenes and Chryseobacterium gleum interact and multiply intracellularly in Acanthamoeba castellanii.

    abstract::Chryseobacterium indologenes and Chryseobacterium gleum are Gram negative environmental bacteria that have been frequently reported to implicate in fatal nosocomial infections, such as bacteraemia and ventilator-associated pneumonia in immunocompromised individuals in the past decades. The interaction between Chryseob...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Lim WG,Tong T,Chew J

    更新日期:2020-02-19 00:00:00

  • Plasmodium berghei: partial purification and characterization of the mitochondrial cytochrome c oxidase.

    abstract::Mitochondria from a rodent malarial parasite (Plasmodium berghei) were successfully purified by differential centrifugation and 22% Percoll density gradient separation. The purified mitochondria from the erythrocytic stages of the parasite had a density of 1.05 and were found to be heterogeneous by transmission electr...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Krungkrai J,Krungkrai SR,Bhumiratana A

    更新日期:1993-09-01 00:00:00

  • Energy allocation patterns in Biomphalaria alexandrina snails in response to cadmium exposure and Schistosoma mansoni infection.

    abstract::This study was aimed to investigate the effects of both parasitism and environmental stress on the growth, reproduction, and survival of Biomphalaria alexandrina snails. Resource allocation strategies may be influenced by both biotic and abiotic factors. Using the planorbid snail B. alexandrina and Schistosoma mansoni...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Ibrahim MM

    更新日期:2006-01-01 00:00:00

  • Light and scanning electron microscopy study of in vitro effects of artesunate in newly excysted metacercariae of Echinostoma paraensei (Trematoda: Digenea).

    abstract::Chemotherapy of food-borne trematodes relies on two drugs, praziquantel and tricabendazole, and there is growing interest in finding alternative therapies. Plant oil extracts have long been used in traditional Chinese medicine as sources of bioactive compounds with antiparasitic activity. Species of the genus Echinost...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Souza JG,Lopes Torres EJ,Garcia JS,Gomes AP,Rodrigues-Silva R,Maldonado A Jr,Machado-Silva JR

    更新日期:2017-03-01 00:00:00

  • Neolignans from plants in northeastern Brazil (Lauraceae) with activity against Trypanosoma cruzi.

    abstract::Trypanosoma cruzi is the ethiological agent for Chagas disease in Latin America. This study aimed to test the trypanocidal effect of licarin A and burchellin isolated from plants in northeastern Brazil. These neolignans were tested on T. cruzi and on peritoneal macrophages, to evaluate drug toxicity. Epimastigote grow...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Cabral MM,Barbosa-Filho JM,Maia GL,Chaves MC,Braga MV,De Souza W,Soares RO

    更新日期:2010-03-01 00:00:00

  • Steinernema feltiae: ammonia triggers the emergence of their infective juveniles.

    abstract::Entomopathogenic nematodes complete their life cycles inside dead insects. The emergence of new infective juveniles from the cadaver has been attributed (but never demonstrated) to food depletion or to the accumulation of metabolites from the breakdown of the host's tissues. Here we give evidence that emergence is tri...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: San-Blas E,Gowen SR,Pembroke B

    更新日期:2008-05-01 00:00:00

  • Toxoplasma gondii: kinetics of lymphocyte subsets in blood and spleen of perorally infected mice.

    abstract::The blood and spleen lymphocyte subsets and parasite burdens in blood, lungs, and brain were determined serially in C57B1/6 mice infected with an avirulent strain of Toxoplasma gondii. Five mice were sacrificed at various time points after infection; Thy1-2+, Ly5+, CD4+, CD8+, and Ly6c+ lymphocyte subsets and macropha...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Carrof B,Levacher-Clergeot M,Chau F,Pocidalo JJ,Derouin F

    更新日期:1994-06-01 00:00:00

  • Identification and characterization of profilin antigen among Babesia species as a common vaccine candidate against babesiosis.

    abstract::We have characterized a member of the profilin (PROF) family protein as a common antigen in three pathogens-Babesia bovis (B. bovis), Babesia bigemina (B. bigemina), and Babesia microti (B. microti)-and evaluated its immunogenic and cross-protective properties against a challenge infection with B. microti in BALB/c mi...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Munkhjargal T,Aboge GO,Ueno A,Aboulaila M,Yokoyama N,Igarashi I

    更新日期:2016-07-01 00:00:00

  • Brachymeria lasus: effects of nutrient level on in vitro larval growth of a chalcid insect parasite.

    abstract::Exponential weight gain equations and growth rates were determined during larval development of Brachymeria lasus reared aseptically on chemically defined media with varying amino acid and glucose levels. The rate of weight gain increased from 0 to 2% dietary glucose and mean growth rate increased from 160 to 260 micr...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Thompson SN

    更新日期:1983-06-01 00:00:00

  • Effect of ensilation of potato on viability of Taenia hydatigena eggs.

    abstract::A Taenia hydatigena model was used to assess the effect 0, 7, 14, 21, and 28 days of ensilation of minced potato on viability of tapeworm eggs. For infection of lambs, 2,000 T. hydatigena eggs were ensiled for 0, 7, 14, 21 and 28 days in minced potato at 22°C and fed to recently weaned lambs (29.9±0.76 kg). At slaught...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Buttar BS,Nelson ML,Busboom JR,Hancock DD,Walsh DB,Jasmer DP

    更新日期:2013-04-01 00:00:00

  • Evaluating the GCN5b bromodomain as a novel therapeutic target against the parasite Toxoplasma gondii.

    abstract::Toxoplasma gondii is a protozoan parasite of great importance in human and veterinary health. The frontline treatment of antifolates suffers a variety of drawbacks, including toxicity and allergic reactions, underscoring the need to identify novel drug targets for new therapeutics to be developed. We previously showed...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Hanquier J,Gimeno T,Jeffers V,Sullivan WJ Jr

    更新日期:2020-02-28 00:00:00

  • Toxoplasma gondii: purification of zoites from peritoneal exudates by eight methods.

    abstract::Many methods have been proposed for removing contaminating host cells from mouse peritoneal exudates infected with Toxoplasma gondii tachyzoites. Of these, eight established methods were compared. They were density gradients, sonication and trypsin digestion, differential centrifugation, haemolysin digestion, filtrati...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Dempster RP

    更新日期:1984-04-01 00:00:00

  • Giardia lamblia: the effects of extracts and fractions from Mentha x piperita Lin. (Lamiaceae) on trophozoites.

    abstract::Giardia lamblia is a parasite that causes giardiasis in humans and other mammals. The common treatment includes different classes of drugs, which were described to produce unpleasant side effects. Mentha x piperita, popularly known as peppermint, is a plant that is frequently used in the popular medicine to treat gast...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Vidal F,Vidal JC,Gadelha AP,Lopes CS,Coelho MG,Monteiro-Leal LH

    更新日期:2007-01-01 00:00:00

  • Plasmodium berghei: diet and drug dosage regimens influencing selection of drug-resistant parasites in mice.

    abstract::Two different diets for the host and three drug dosage regimens were used to select lines resistant to sulfadoxine and pyrimethamine from the parent strain of the rodent malaria parasite Plasmodium berghei [the N (K173) strain]. A higher yield of resistance was obtained when a high parasitemia was present at the begin...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Merkli B,Richle R

    更新日期:1983-06-01 00:00:00

  • Strongyloides stercoralis: protective immunity to third-stage larvae inBALB/cByJ mice.

    abstract::A murine model system was developed to study the induction and mechanism of protective immunity to L3 of Strongyloides stercoralis. L3 were implanted in BALB/cByJ mice in diffusion chambers constructed with 0.1- or 2.0-microns-pore-size membranes. Parasites survived equally well regardless or membrane type for 7 days,...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Abraham D,Rotman HL,Haberstroh HF,Yutanawiboonchai W,Brigandi RA,Leon O,Nolan TJ,Schad GA

    更新日期:1995-03-01 00:00:00

  • Plasmodium falciparum: D260, an intraerythrocytic parasite protein, is a member of the glutamic acid dipeptide-repeat family of proteins.

    abstract::Members of a serologically cross-reacting family of proteins including Ag332 and Pf11.1, megadalton proteins of schizont-infected red blood cells, and gametocytes, respectively, and Pf155-RESA, a 155-kDa protein of ring-infected red blood cells, have been reported to share amino acid repeat sequences. These repeats ar...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Barnes DA,Wollish W,Nelson RG,Leech JH,Petersen C

    更新日期:1995-08-01 00:00:00

  • Molecular identification of Vermamoeba vermiformis from freshwater fish in lake Taal, Philippines.

    abstract::Free Living Amoebae (FLA) are considered ubiquitous. FLAs may infect various biological organisms which act as reservoir hosts. Infected freshwater fishes can pose a public health concern due to possible human consumption. This study aims to identify possible pathogenic FLAs present in freshwater fishes. Seventy five ...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Milanez GD,Masangkay FR,Thomas RC,Ordona MOGO,Bernales GQ,Corpuz VCM,Fortes HSV,Garcia CMS,Nicolas LC,Nissapatorn V

    更新日期:2017-12-01 00:00:00

  • Plasmodium: genus-conserved primers for species identification and quantitation.

    abstract::Stable RNAs have regions of primary sequence that are nearly identical in every member of the Plasmodium genus and not found in the host or in other common pathogens. Several "genus-conserved" sequences, which flank hypervariable regions, were identified within the small subunit ribosomal RNA of Plasmodium species. Pr...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Li J,Wirtz RA,McConkey GA,Sattabongkot J,Waters AP,Rogers MJ,McCutchan TF

    更新日期:1995-09-01 00:00:00

  • Nematospiroides dubius: influence of adjuvants on immunity in mice vaccinated with antigens isolated by affinity chromatography from adult worms.

    abstract::Five adjuvants were examined for their ability to potentiate the immune response of mice to soluble antigens from adult Nematospiroides dubius prepared by affinity chromatography against antibodies from repeatedly infected mice as ligands (IMIgAg). Immunized mice were better protected against N. dubius by IMIgAg injec...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Monroy FG,Adams JH,Dobson C,East IJ

    更新日期:1989-01-01 00:00:00

  • Trypanosoma cruzi: possible control of parasite transmission by blood transfusion using amphiphilic cationic drugs.

    abstract::About 200 clinically used amphiphilic cationic drugs have been shown to be active in vitro against Trypanosoma cruzi at concentrations of less than or equal to 1 mM. Activity against epimastigote and trypomastigote forms was similar, and in both cases the most potent drugs were litracene, maprotiline, thioproperazine,...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Hammond DJ,Hogg J,Gutteridge WE

    更新日期:1985-08-01 00:00:00

  • Toxoplasma gondii: a simple Real-time PCR assay to quantify the proliferation of the apicoplast.

    abstract::A Real-time quantitative PCR assay to quantify the Toxoplasma gondii apicoplast was studied. Primers were designed to amplify a 305bp product specific to T. gondii apicoplast. Standard curves were generated for both T. gondii apicoplast DNA and genomic DNA, and were used to compute the relative concentration of apicop...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Wu L,Chen SX,Jiang XG,Cao JP

    更新日期:2009-12-01 00:00:00

  • Ancylostoma caninum: calibration and comparison of diagnostic accuracy of flotation in tube, McMaster and FLOTAC in faecal samples of dogs.

    abstract::We performed a calibration of flotation in tube, McMaster and FLOTAC to determine the optimal flotation solution (FS) and the influence of faecal preservation for the diagnosis of Ancylostoma caninum in dogs, and compared the accuracy of the three copromicroscopic techniques. Among nine different FS, sodium chloride a...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Cringoli G,Rinaldi L,Maurelli MP,Morgoglione ME,Musella V,Utzinger J

    更新日期:2011-05-01 00:00:00

  • Molecular analyses reveal two geographic and genetic lineages for tapeworms, Taenia solium and Taenia saginata, from Ecuador using mitochondrial DNA.

    abstract::Tapeworms Taenia solium and Taenia saginata are the causative agents of taeniasis/cysticercosis. These are diseases with high medical and veterinary importance due to their impact on public health and rural economy in tropical countries. The re-emergence of T. solium as a result of human migration, the economic burden...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Solano D,Navarro JC,León-Reyes A,Benítez-Ortiz W,Rodríguez-Hidalgo R

    更新日期:2016-12-01 00:00:00

  • Plasmodium berghei and Plasmodium chabaudi: a neutral endopeptidase in parasite extracts and plasma of infected animals.

    abstract::By using a sensitive fluorometric method with Val-Leu-Gly-Arg-3-amino-9-ethylcarbazole (VLGR-AEC) as a substrate, two endopeptidase activities were identified in two fractions of Sephacryl S-200 gel filtration from soluble P. berghei and P. chabaudi extracts. Controls with normal mouse erythrocytes, with leukocytes, a...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Bernard F,Mayer R,Picard I,Deguercy A,Monsigny M,Schrevel J

    更新日期:1987-08-01 00:00:00

  • Entamoeba invadens: sphingolipids metabolic regulation is the main component of a PKC signaling pathway in controlling cell growth and proliferation.

    abstract::The sphingolipids biosynthesis pathway generates bioactive molecules crucial to the regulation of physiological processes. We have recently reported that DAG (diacylglycerol) generated during sphingomyelin synthesis, plays an important role in PKC (protein kinase C) activation, necessary for the transit through the ce...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Cerbon J,Olguin T,Alvarez-Grave PR,López-Sánchez RC

    更新日期:2009-06-01 00:00:00

  • Echinococcus granulosus: induction of T-independent antibody response against protoscolex glycoconjugates in early experimental infection.

    abstract::In this work CD4-knockout mice were used as a model to analyse the role of CD4+ T cells in the antibody response against Echinococcus granulosus immunization or experimental infection. Results obtained with mice immunized with protoscolex antigens indicated that these contain T-independent antigens. After infection, C...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Baz A,Carol H,Fernández V,Mourglia-Ettlin G,Nieto A,Orn A,Dematteis S

    更新日期:2008-08-01 00:00:00

  • Entamoeba histolytica: identification of EhGPCR-1, a novel putative G protein-coupled receptor that binds to EhRabB.

    abstract::EhRabB is an Entamoeba histolytica protein involved in phagocytosis. However, proteins that regulate the EhRabB activity are unknown. Here, we report the identification of a putative G protein-coupled receptor of E. histolytica (EhGPCR-1) that binds to EhRabB. By two-hybrid screening, we found a 372-bp cDNA fragment t...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Picazarri K,Luna-Arias JP,Carrillo E,Orozco E,Rodriguez MA

    更新日期:2005-07-01 00:00:00

  • Leishmania (Viannia): genetic analysis of cutaneous and mucosal strains isolated from the same patient.

    abstract::Ten pairs of Leishmania (Viannia) strains isolated from mucosal and cutaneous lesions of the same patient were analyzed genotypically in order to determine whether populations that had metastasized to mucosal sites differed from those in the cutaneous lesion. The strains were previously characterized by multi locus en...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Cuervo P,Cupolillo E,Nehme N,Hernandez V,Saravia N,Fernandes O

    更新日期:2004-09-01 00:00:00

  • Behavioral responses of Poecilia vivipara (Osteichthyies: Cyprinodontiformes) to experimental infections of Acanthocollaritrema umbilicatum (Digenea: Cryptogonimidae).

    abstract::The swimming behavior of Poecilia vivipara was evaluated using an image analysis system comparing laboratory-reared uninfected fish before and after experimental infection with different intensities of cercariae of the trematode Acanthocollaritrema umbilicatum. Two experiments were performed, each with 30 fish which w...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Santos EG,Cunha RA,Santos CP

    更新日期:2011-02-01 00:00:00

  • Characterization and cellular distribution of heat-shock proteins HSP70 and HSP60 in Trypanosoma cruzi.

    abstract::At least eight protein members of HSP70 and three of the HSP60 families have been identified in Trypanosoma cruzi; of these, five HSP70 isoforms and one HSP60 isoform were respectively induced by a 2-hr heat-shock treatment at 37 degrees C. Immunoelectronmicroscopy of epimastigote, spheromastigote, and metacyclic cell...

    journal_title:Experimental parasitology

    pub_type: 杂志文章


    authors: Giambiagi-deMarval M,Souto-Padrón T,Rondinelli E

    更新日期:1996-08-01 00:00:00