Toxoplasma gondii aspartic protease 1 is not essential in tachyzoites.

abstract：:Experiments were carried out to determine whether there are stage-specific antigens on microfilariae of Brugia pahangi, using sera from Mongolian jirds infected with B. pahangi and monoclonal antibodies against microfilariae of B. pahangi. These studies showed that microfilariae have both stage-specific and nonspecifi...

journal_title：Experimental parasitology

authors： Tomisato M,Nariuchi H,Ueno J,Nogami S,Tanaka H,Aoki Y,Nakajima Y

更新日期：1986-02-01 00:00:00

abstract：:The present work evaluates the anti-Giardia activity of Syzygium aromaticum and its major compound eugenol. The effects were evaluated on parasite growth, adherence, viability and ultrastructure. S. aromaticum essential oil (IC(50)=134 μg/ml) and eugenol (IC(50)=101 μg/ml) inhibited the growth of G. lamblia. The essen...

journal_title：Experimental parasitology

authors： Machado M,Dinis AM,Salgueiro L,Custódio JB,Cavaleiro C,Sousa MC

更新日期：2011-04-01 00:00:00

abstract：:This study was aimed to investigate the effects of both parasitism and environmental stress on the growth, reproduction, and survival of Biomphalaria alexandrina snails. Resource allocation strategies may be influenced by both biotic and abiotic factors. Using the planorbid snail B. alexandrina and Schistosoma mansoni...

journal_title：Experimental parasitology

authors： Ibrahim MM

更新日期：2006-01-01 00:00:00

abstract：:Branchial bopyrids infesting porcellanid crabs from the Philippines were investigated based on intertidal collections made in 1999-2000. Crabs of the genus Petrolisthes collected from sites in the northern Philippines were examined and two parasite species were found. One new pseudionine species found infesting Petrol...

journal_title：Experimental parasitology

authors： Williams JD,Madad AZ

更新日期：2010-05-01 00:00:00

abstract：:Acanthamoeba are free-living amoebae found in most environments that can cause brain and corneal infections. To infect humans, these pathogens must interact with host cells and the extracellular matrix (ECM). In order to define the mode by which amoebae recognize ECM components and process this recognition, we analyze...

journal_title：Experimental parasitology

authors： Rocha-Azevedo Bd,Jamerson M,Cabral GA,Marciano-Cabral F

更新日期：2010-09-01 00:00:00

abstract：:Acanthamoeba is a free-living amoeba genus that causes several diseases namely, amoebic keratitis which is a painful sight threatening eyes disease. Its treatment is difficult and the exploration for new drugs is very important. The main objective of the present study was to evaluate the chemical composition of the Es...

journal_title：Experimental parasitology

authors： Souhaiel N,Sifaoui I,Ben Hassine D,Bleton J,Bonose M,Moussa F,Piñero JE,Lorenzo-Morales J,Abderrabba M

更新日期：2017-12-01 00:00:00

abstract：:Toxoplasma gondii invades any nucleated cell, but different replication speed and effects on survival/apoptosis processes have been found depending on cell type. There are scarce and controversial results regarding the effect of this parasite on host cell apoptosis within the brain. The invasion and replication of T. ...

journal_title：Experimental parasitology

authors： Contreras-Ochoa CO,Lagunas-Martínez A,Belkind-Gerson J,Díaz-Chávez J,Correa D

更新日期：2013-06-01 00:00:00

abstract：:Inbred strains of mice differ in their susceptibility and resistance to challenge infections with Nematospiroides dubius. In our studies, F1 hybrid mice from resistant SJL and susceptible CBA parents were resistant to N. dubius challenge infections. Only 22% of backcrosses to SJL were susceptible while backcrosses to ...

journal_title：Experimental parasitology

authors： Enriquez FJ,Zidian JL,Cypess RH

更新日期：1988-10-01 00:00:00

abstract：:Complement activation by protoscoleces of Echinococcus granulosus was studied by analyzing the damage to their tegumental membrane produced by incubation in both normal and hydatid human sera. The state of the apical tegumental membrane was evaluated by measuring the electric potential difference with microelectrodes....

journal_title：Experimental parasitology

authors： Ferreira AM,Trecu T,Reisin I

更新日期：1992-11-01 00:00:00

abstract：:Serine hydroxymethyltransferase belongs to the class of pyridoxal-5-phosphate enzymes along with aspartate aminotransferase. To explore the function of residue(s) involved in binding of the carboxylate group of Tetrahydrofolic acid (THF) to L. donovani cytosolic serine hydroxymethyltransferase (LdcSHMT), the gene was ...

journal_title：Experimental parasitology

authors： Gandhi S,Gaur N,Krishna S,Siddiqi MI,Saxena JK

更新日期：2015-02-01 00:00:00

abstract：:The anthelmintic effects of plumbagin (PB, 5-hydroxy-2-methyl-1,4-naphthoquinone) and praziquantel (PZQ) against adult Schistosoma mansoni in vitro were compared by estimating the relative motility (RM) values, survival indices (SI) and alterations of the tegument of flukes incubated in M-199 medium containing 1, 10 a...

journal_title：Experimental parasitology

authors： Lorsuwannarat N,Saowakon N,Ramasoota P,Wanichanon C,Sobhon P

更新日期：2013-01-01 00:00:00

abstract：:We have identified congenic mouse strains that differ dramatically in resistance to infection with the murine malaria parasite Plasmodium yoelii 17X. After infection, BALB/c mice develop severe anemia and a high degree of parasitemia which sometimes results in death. The mtv-7 congenic strain BALB.D2.mlsa, however, de...

journal_title：Experimental parasitology

authors： Swardson CJ,Wassom DL,Avery AC

更新日期：1997-06-01 00:00:00

abstract：:The oocysts of Eimeria tenella, one of the most pathogenic of several species causing chicken coccidiosis, are difficult to distinguish microscopically from several other infective Eimeria species. One copy of a gene coding for 5S ribosomal RNA has been cloned from E. tenella and sequenced. A coding region of 120 nucl...

journal_title：Experimental parasitology

authors： Stucki U,Braun R,Roditi I

更新日期：1993-02-01 00:00:00

abstract：:In this work we demonstrated that promastigotes of Leishmania amazonensis exhibit an Mg-dependent ecto-ATPase activity, which is stimulated by heat shock. The Mg-dependent ATPase activity of cells grown at 22 and 28 degrees C was 41.0+/-5.2 nmol Pi/h x 10(7)cells and 184.2+/-21.0 nmol Pi/h x 10(7)cells, respectively. ...

journal_title：Experimental parasitology

authors： Peres-Sampaio CE,de Almeida-Amaral EE,Giarola NL,Meyer-Fernandes JR

更新日期：2008-05-01 00:00:00

abstract：:In mice concurrently infected with Hymenolepis citelli and Nematospiroides dubius, survival of the tapeworm was prolonged, and there was an impairment of the efferent arm of the response to the cestode. The immunological rejection of a six cysticercoid primary H. citelli infection was delayed by the N. dubius infectio...

journal_title：Experimental parasitology

authors： Alghali ST,Hagan P,Robinson M

更新日期：1985-12-01 00:00:00

abstract：:Triosephosphate isomerase (TIM) is a major enzyme in the glycolytic pathway, which catalyzes the interconversion of glyceraldehyde 3-phosphate to dihydroxyacetone phosphate. Here, we report cloning, expression and purification of a catalytically active recombinant TIM of Leishmania donovani (LdTIM). The recombinant Ld...

journal_title：Experimental parasitology

authors： Kumar K,Bhargava P,Roy U

更新日期：2012-04-01 00:00:00

abstract：:Isospora suis is an intestinal protozoan parasite in pigs. The 2-3 weeks old piglets are most often infected by I. suis because their immune system is not fully developed. The infection exhibits clinical features such as diarrhea and dehydration and seriously affects the economic interests of farmers. The traditional ...

journal_title：Experimental parasitology

authors： Huang C,Wen F,Yue L,Chen R,Zhou W,Hu L,Chen M,Wang S

更新日期：2016-06-01 00:00:00

abstract：:Members of the zinc-regulated transporter/iron-regulated transporter-like protein (ZIP) family of proteins transport metal ions across cell membranes. Genes encoding ZIPs are present in the genomes of schistosomes. Here, we describe molecular characterisation of six ZIPs (SjZIPA-F) from Schistosoma japonicum. Quantita...

journal_title：Experimental parasitology

authors： Schulte L,Glanfield A,Nawaratna S,Gobert GN,McManus DP,Jones MK

更新日期：2011-04-01 00:00:00

abstract：:Certain model inhibitors exerted selective action against the catalytic activity of nuclear DNA topoisomerase II (TOPII) of Leishmania panamensis promastigotes. The second-generation fluoroquinolones enoxacin and ciprofloxacin exhibited extraordinarily high anti-parasite selectivity displaying 582- and 40-fold greater...

journal_title：Experimental parasitology

authors： Cortázar TM,Coombs GH,Walker J

更新日期：2007-08-01 00:00:00

abstract：:Only two drugs are currently available for the treatment of Chagas disease and their effectiveness are unsatisfactory. Photorhabdus luminescens and Xenorhabdus nematophila, two enteric bacteria highly pathogenic to a broad range of insects, have been studied as potential source for bioactive metabolites against protoz...

journal_title：Experimental parasitology

authors： Antonello AM,Sartori T,Silva MB,Prophiro JS,Pinge-Filho P,Heermann R,da Silva OS,Romão PRT

更新日期：2019-09-01 00:00:00

abstract：:Previously generated two auxotrophic genes knockout Edwardsiella tarda (Δalr Δasd E. tarda) was used as a delivery vehicle for CpG 1668 motif-enriched plasmids (pL-CpG30), and potential of the Δalr Δasd E. tarda-mediated delivery of CpG motifs in both prevention and therapeutic treatment of scuticociliatosis caused by...

journal_title：Experimental parasitology

authors： Kang YJ,Choi SH,Kim KH

更新日期：2014-09-01 00:00:00

abstract：:The glycosomes of trypanosomatids are essential organelles that are evolutionarily related to peroxisomes of other eukaryotes. The peroxisomal RING proteins-PEX2, PEX10 and PEX12-comprise a network of integral membrane proteins that function in the matrix protein import cycle. Here, we describe PEX10 and PEX12 in Tryp...

journal_title：Experimental parasitology

authors： Saveria T,Kessler P,Jensen BC,Parsons M

更新日期：2007-05-01 00:00:00

abstract：:Clonorchis sinensis is a fish-borne trematode endemic to East Asia, which infects over 35 million people globally. In the study described here, we developed a nested polymerase chain reaction (PCR) method for the specific and reliable detection of C. sinensis. The primers designed from the nucleotide sequence data der...

journal_title：Experimental parasitology

authors： Parvathi A,Sanath Kumar H,Kenchanna Prakasha B,Lu J,Xu X,Hu W,Feng Z,Karunasagar I,Karunasagar I

更新日期：2007-03-01 00:00:00

abstract：:The yellow fever mosquito, Aedes aegypti, expresses a gene, Apyrase (Apy), that encodes an ATP-diphosphohydrolase. The product of this gene is a secreted enzyme that facilitates hematophagy by preventing platelet aggregation in the host. Apy gene expression is limited to the cells of the distal-lateral and medial lobe...

journal_title：Experimental parasitology

authors： Smartt CT,Kim AP,Grossman GL,James AA

更新日期：1995-11-01 00:00:00

abstract：:Nitric oxide (NO) has diverse biological functions. Numerous studies have documented NO's biosynthetic pathway in a wide variety of organisms. Little is known, however, about NO production in intraerythrocytic Plasmodium falciparum. Using diaminorhodamine-4-methyl acetoxymethylester (DAR-4M AM), a fluorescent indicato...

journal_title：Experimental parasitology

authors： Ostera G,Tokumasu F,Oliveira F,Sa J,Furuya T,Teixeira C,Dvorak J

更新日期：2008-09-01 00:00:00

abstract：:Monoclonal antibodies (mAb) directed against Schistosoma mansoni tropomyosin isoform, SMTM (Xu et al. Experimental Parasitology 69, 373-392, 1989), were used to test for cross-reactivity with Biomphalaria glabrata antigens. One mAb (1F10) recognized antigens of 39, 41, and 80 kDa in a snail head/foot antigen preparati...

journal_title：Experimental parasitology

authors： Weston D,Allen B,Thakur A,LoVerde PT,Kemp WM

更新日期：1994-05-01 00:00:00

abstract：:The anthelmintic fenbendazole (FBZ) induces nuclear DNA fragmentation (DF) in intestinal cells of Haemonchus contortus. The DNA fragments had 3'-OH, which suggests involvement of a neutral DNase. To identify candidate DNase(s) involved, DNase activity in H. contortus intestine and other worm fractions was characterize...

journal_title：Experimental parasitology

authors： Kwak D,Jasmer DP

更新日期：2003-07-01 00:00:00

abstract：:We report here the pre-mRNA 3' end processing machinery in Entamoeba histolytica. Comparative analysis of the putative sequences participating in the pre-mRNA 3' end processing of E. histolytica genes shows similitude and differences to those described for yeast and human transcripts. By a genomic survey, we identifie...

journal_title：Experimental parasitology

authors： López-Camarillo C,Orozco E,Marchat LA

更新日期：2005-07-01 00:00:00

abstract：:The diagnostic potential of recombinant E/S antigens of the lymphatic filaria Brugia malayi was investigated by Western blot. A cDNA expression library was constructed using B. malayi male adult worm mRNA, and E/S recombinants were identified with a rabbit antiserum raised against E/S products collected in vitro from ...

journal_title：Experimental parasitology

authors： Kumari S,Lillibridge CD,Bakeer M,Lowrie RC Jr,Jayaraman K,Philipp MT

更新日期：1994-12-01 00:00:00

abstract：:Previous results from our laboratory using pharmacological approaches suggested a role for nitric oxide (NO) in the host defense against the human filarial parasite, Brugia malayi. We sought to determine whether a complementary genetic approach, using mice homozygous for a targeted mutation in the gene encoding induci...

journal_title：Experimental parasitology

authors： Ganley L,Babu S,Rajan TV

更新日期：2001-05-01 00:00:00