Ascaris suum: role of ecdysteroids in molting.

Abstract:

:Three studies were conducted to examine the function of ecdysteroids in the development of parasitic nematodes. Ecdysone and 20-hydroxyecdysone were extracted, separated chromatographically, and measured in the reproductive tracts of adult female Ascaris suum. Perienteric fluid and the body wall did not contain measurable levels of these steroids. Levels of 20-hydroxyecdysone were correlated with the third and fourth molts of larvae grown in vitro from the third stage. In a bioassay, addition of ecdysteroid extracted from the female reproductive tract or synthetic ecdysteroid increased the proportion of third-stage larvae that molted after 4 days in culture. This evidence supports the role of ecdysteroids in molting in A. suum, as well as suggesting a function in gametogenesis and embryogenesis.

journal_name

Exp Parasitol

authors

Fleming MW

doi

10.1016/0014-4894(85)90024-4

subject

Has Abstract

pub_date

1985-10-01 00:00:00

pages

207-10

issue

2

eissn

0014-4894

issn

1090-2449

pii

0014-4894(85)90024-4

journal_volume

60

pub_type

杂志文章
  • Molecular typing of the actin gene of Trichomonas vaginalis isolates by PCR-RFLP in Iran.

    abstract::Trichomonas vaginalis is a human urogenital pathogen that causes trichomoniasis, the most common nonviral, parasitic sexually transmitted infection in the world. At present, little is known regarding the degree of strain variability of T. vaginalis. A classification method for T. vaginalis strains would be a useful to...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2015.10.011

    authors: Momeni Z,Sadraei J,Kazemi B,Dalimi A

    更新日期:2015-12-01 00:00:00

  • Production of MMP-9 and inflammatory cytokines by Trypanosoma cruzi-infected macrophages.

    abstract::Matrix metalloproteinases (MMPs) constitute a large family of Zn(2+) and Ca(2+) dependent endopeptidases implicated in tissue remodeling and chronic inflammation. MMPs also play key roles in the activation of growth factors, chemokines and cytokines produced by many cell types, including lymphocytes, granulocytes, and...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2014.09.003

    authors: de Pinho RT,da Silva WS,de Castro Côrtes LM,da Silva Vasconcelos Sousa P,de Araujo Soares RO,Alves CR

    更新日期:2014-12-01 00:00:00

  • Plasmodium falciparum: D260, an intraerythrocytic parasite protein, is a member of the glutamic acid dipeptide-repeat family of proteins.

    abstract::Members of a serologically cross-reacting family of proteins including Ag332 and Pf11.1, megadalton proteins of schizont-infected red blood cells, and gametocytes, respectively, and Pf155-RESA, a 155-kDa protein of ring-infected red blood cells, have been reported to share amino acid repeat sequences. These repeats ar...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1995.1095

    authors: Barnes DA,Wollish W,Nelson RG,Leech JH,Petersen C

    更新日期:1995-08-01 00:00:00

  • Giardia lamblia: the effects of extracts and fractions from Mentha x piperita Lin. (Lamiaceae) on trophozoites.

    abstract::Giardia lamblia is a parasite that causes giardiasis in humans and other mammals. The common treatment includes different classes of drugs, which were described to produce unpleasant side effects. Mentha x piperita, popularly known as peppermint, is a plant that is frequently used in the popular medicine to treat gast...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2006.05.001

    authors: Vidal F,Vidal JC,Gadelha AP,Lopes CS,Coelho MG,Monteiro-Leal LH

    更新日期:2007-01-01 00:00:00

  • Targeting epimastigotes of Trypanosoma cruzi with a peptide isolated from a phage display random library.

    abstract::Chagas disease, also known as American trypanosomiasis, is a potentially life-threatening illness caused by the protozoan parasite Trypanosoma cruzi, which is transmitted by insects of the family Reduviidae. Since conventional treatments with nitroheterocyclic drugs show serious adverse reactions and have questionable...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2020.107830

    authors: Sáenz-Garcia JL,Yamanaka IB,Pacheco-Lugo LA,Miranda JS,Córneo ES,Machado-de-Ávila RA,De Moura JF,DaRocha WD

    更新日期:2020-03-01 00:00:00

  • Trypanosomatidae: a spliced-leader-derived probe specific for the genus Phytomonas.

    abstract::We probed DNA from all trypanosomatid genera by slot blot hybridization with an oligonucleotide (SL3') complementary to a sequence of the Phytomonas spliced-leader or mini-exon RNA. The 19-nucleotide probe target site was previously shown to be highly conserved among a limited number of Phytomonas isolates, but diverg...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1996.0119

    authors: Teixeira MM,Serrano MG,Nunes LR,Campaner M,Buck GA,Camargo EP

    更新日期:1996-12-01 00:00:00

  • A family of serine protease inhibitors (serpins) in the cattle tick Rhipicephalus (Boophilus) microplus.

    abstract::Proteins belonging to the serine protease inhibitor (serpin) superfamily play essential roles in many organisms. In arthropods these proteins are involved in innate immune system, morphogenesis and development. In mammals serpins regulate pathways that are essential to life such as blood coagulation, fibrinolysis, inf...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2013.12.001

    authors: Tirloni L,Seixas A,Mulenga A,Vaz Ida S Jr,Termignoni C

    更新日期:2014-02-01 00:00:00

  • Trypanosoma cruzi: Oxidative stress induces arginine kinase expression.

    abstract::Trypanosoma cruzi arginine kinase is a key enzyme in cell energy management and is also involved in pH and nutritional stress response mechanisms. T. cruzi epimastigotes treated with hydrogen peroxide presented a time-dependent increase in arginine kinase expression, up to 10-fold, when compared with untreated parasit...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2006.04.004

    authors: Miranda MR,Canepa GE,Bouvier LA,Pereira CA

    更新日期:2006-12-01 00:00:00

  • Fasciolosis in India: An overview.

    abstract::Fasciolosis in ruminants is a relentless constraint in the livestock industry across the world. Immuno-prophylactic vaccines against fasciolosis may not come up in near future, rendering the control of this scourge with chemotherapy and snail population control. With the alarming threats of anti-fasciolid drug resista...

    journal_title:Experimental parasitology

    pub_type: 杂志文章,评审

    doi:10.1016/j.exppara.2021.108066

    authors: Lalrinkima H,Lalchhandama C,Jacob SS,Raina OK,Lallianchhunga MC

    更新日期:2021-01-12 00:00:00

  • IFN-γ-induced macrophage antileishmanial mechanisms in mice: A role for immunity-related GTPases, Irgm1 and Irgm3, in Leishmania donovani infection in the liver.

    abstract::In C57BL/6 mice, Leishmania donovani infection in the liver provoked IFN-γ-induced expression of the immunity-related GTPases (IRG), Irgm1 and Irgm3. To gauge the antileishmanial effects of these macrophage factors in the liver, intracellular infection was analyzed in IRG-deficient mice. In early- (but not late-) stag...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2015.07.005

    authors: Murray HW,Mitchell-Flack M,Taylor GA,Ma X

    更新日期:2015-10-01 00:00:00

  • Energy allocation patterns in Biomphalaria alexandrina snails in response to cadmium exposure and Schistosoma mansoni infection.

    abstract::This study was aimed to investigate the effects of both parasitism and environmental stress on the growth, reproduction, and survival of Biomphalaria alexandrina snails. Resource allocation strategies may be influenced by both biotic and abiotic factors. Using the planorbid snail B. alexandrina and Schistosoma mansoni...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2005.08.012

    authors: Ibrahim MM

    更新日期:2006-01-01 00:00:00

  • Plasmodium falciparum: allelic variation in the merozoite surface protein 1 gene in wild isolates from southern Vietnam.

    abstract::Allelic variation in the Plasmodium falciparum merozoite surface protein 1 (MSP1) gene is expressed as an association of allelic types in variable blocks. In this study, a PCR strategy that can detect 24 different MSP1 association types was used to investigate allelic variation in the MSP1 gene. We identified 236 dist...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1997.4147

    authors: Kaneko O,Kimura M,Kawamoto F,Ferreira MU,Tanabe K

    更新日期:1997-05-01 00:00:00

  • Plasmodium falciparum: the effect of pH and Ca2+ concentration on the in vitro cytoadherence of infected erythrocytes to amelanotic melanoma cells.

    abstract::Cytoadherence of Plasmodium falciparum-infected erythrocytes to amelanotic melanoma cells was pH dependent; increased adherence was observed in the pH range of 6.1 to 6.8 and was greatest between pH 6.6 and 6.8 Ca2+ promoted cytoadherence, but at higher concentrations (40-50 mM) than is usually the case for cell-cell ...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/0014-4894(91)90108-9

    authors: Crandall I,Smith H,Sherman IW

    更新日期:1991-10-01 00:00:00

  • Selective pressure can influence the resistance of Trypanosoma congolense to normal human serum.

    abstract::Resistance and sensitivity to normal human serum (NHS) of Trypanosoma congolense, a parasite believed to cause disease in animals only, were investigated in vivo as well as in vitro. Our results indicate that like Trypanosoma brucei, T. congolense can be grouped into three different phenotypes according to its resista...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/s0014-4894(03)00032-8

    authors: Xong HV,De Baetselier P,Pays E,Magez S

    更新日期:2002-10-01 00:00:00

  • The cytostome of Trypanosoma cruzi epimastigotes is associated with the flagellar complex.

    abstract::Okuda, K., Esteva, M., Segura, E. L., and Bijovsky, A. T. 1999. The cytostome of Trypanosoma cruzi epimastigotes is associated with the flagellar complex. Experimental Parasitology 92, 223-231. Proliferative forms of Trypanosoma cruzi, amastigotes and epimastigotes, have a cytostome, a specialized structure formed by ...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1999.4419

    authors: Okuda K,Esteva M,Segura EL,Bijovsy AT

    更新日期:1999-08-01 00:00:00

  • Cellular and transcriptional changes during excystation of Giardia lamblia in vitro.

    abstract::Excystation of Giardia lamblia entails differentiation of dormant cysts into parasitic trophozoites. Despite its importance for infection, this transformation is not understood at the cellular or molecular levels. In these studies, we report that excystation entails detection of environmental stimuli across the tough ...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1998.4246

    authors: Hetsko ML,McCaffery JM,Svärd SG,Meng TC,Que X,Gillin FD

    更新日期:1998-03-01 00:00:00

  • Lentivirus-mediated over-expression of let-7b microRNA suppresses hepatic fibrosis in the mouse infected with Schistosoma japonicum.

    abstract::Transforming growth factor-β (TGF-β) signaling pathway is documented to participate in liver fibrosis via multifactorial mechanisms. microRNA Let-7b (Let-7b) has been proved to alleviate cell fibrosis through regulating TGF-β receptor I (TβRI), but whether it is involved in Schistosomiasis liver fibrosis (SLF) has not...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2017.09.024

    authors: Tang N,Wu Y,Cao W,Liang Y,Gao Y,Hu L,Yang Q,Zhou Y,Tang F,Xiao J

    更新日期:2017-11-01 00:00:00

  • Brugia pahangi: immunization with early L3 ES alters parasite migration, and reduces microfilaremia and lymphatic lesion formation in gerbils (Meriones unguiculatus).

    abstract::Previous studies have shown that intradermally (ID) injected Brugia pahangi L3 s migrate through various tissues and into the lymphatics of gerbils in a distinct pattern. Excretory/secretory products (ES) produced at the time of invasion of B. pahangi are likely to be important in this early migration phase of the par...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2013.08.007

    authors: Zipperer GR,Arumugam S,Chirgwin SR,Coleman SU,Shakya KP,Klei TR

    更新日期:2013-10-01 00:00:00

  • Toxoplasma gondii: characterization and localization of antigens secreted from tachyzoites.

    abstract::Since we had previously demonstrated the protective role played by Toxoplasma excreted-secreted antigens, the aim of the present work was to produce monoclonal antibodies directed against these antigens in order to determine if their localization in the parasite is compatible with a mechanism of excretion or secretion...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/0014-4894(90)90014-4

    authors: Charif H,Darcy F,Torpier G,Cesbron-Delauw MF,Capron A

    更新日期:1990-07-01 00:00:00

  • Vaccination of sheep with purified cysteine proteinases of Fasciola hepatica decreases worm fecundity.

    abstract::There has been some evidence from several parasite systems that proteinases might have potential as protective antigens against parasitic infection. A cysteine proteinase complex identified in the regurgitant of adult F. hepatica was examined in this context. The thiol-cathepsin-related proteinases of M(r) 28,000 were...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1994.1014

    authors: Wijffels GL,Salvatore L,Dosen M,Waddington J,Wilson L,Thompson C,Campbell N,Sexton J,Wicker J,Bowen F

    更新日期:1994-03-01 00:00:00

  • Trypanosoma brucei: a survey of pyrimidine transport activities.

    abstract::Purine uptake has been studied in many protozoan parasites in the last few years, and several of the purine transporters have been cloned. In contrast, very little is known about the salvage of preformed pyrimidines by protozoa, and no pyrimidine transporters have been cloned, yet chemotherapy based on pyrimidine nucl...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2006.02.018

    authors: Gudin S,Quashie NB,Candlish D,Al-Salabi MI,Jarvis SM,Ranford-Cartwright LC,de Koning HP

    更新日期:2006-10-01 00:00:00

  • Leishmania chagasi: a tetracycline-inducible cell line driven by T7 RNA polymerase.

    abstract::Trypanosomatid protozoa lack consensus promoters for RNA polymerase (RNAP) II. However, the artificial insertion of the T7 promoter (P(T7)) and the tetracycline repressor into Trypanosoma brucei cell lines expressing T7RNAP allows P(T7)-driven gene expression to be tetracycline-inducible. These cell lines provide a mo...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2007.01.001

    authors: Yao C,Luo J,Hsiao CH,Donelson JE,Wilson ME

    更新日期:2007-07-01 00:00:00

  • Toxoplasma gondii: chimeric Dr fimbriae as a recombinant vaccine against toxoplasmosis.

    abstract::Toxoplasma gondii is responsible for fetopathy in farm animals and humans and severe disease in immunocompromised individuals (i.e. AIDS patients). Effective vaccines, inducing protective and long-lasting immunity to this global parasite, are still desired. In the work, we evaluated the immunogenic and immunoprotectiv...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2007.07.003

    authors: Gatkowska J,Gasior A,Kur J,Dlugonska H

    更新日期:2008-02-01 00:00:00

  • Exploration of fluorescence-based real-time loop-mediated isothermal amplification (LAMP) assay for detection of Isospora suis oocysts.

    abstract::Isospora suis is an intestinal protozoan parasite in pigs. The 2-3 weeks old piglets are most often infected by I. suis because their immune system is not fully developed. The infection exhibits clinical features such as diarrhea and dehydration and seriously affects the economic interests of farmers. The traditional ...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2016.03.001

    authors: Huang C,Wen F,Yue L,Chen R,Zhou W,Hu L,Chen M,Wang S

    更新日期:2016-06-01 00:00:00

  • Behavioral changes in host foraging: Experiments with Clinostomum (Trematoda, Digenea) parasitizing Loricariichthys platymetopon (Loricariidae).

    abstract::Complex life cycle parasites can manipulate the behavior of intermediate hosts in order to reduce their fitness and increase the chance of completing life cycle. In order to understand the effects of the trematode parasites of the genus Clinostomum on host fish Loricariichthys platymetopon, a filmed experiment was car...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2020.107916

    authors: Nicola DN,Affonso IP,Takemoto RM

    更新日期:2020-09-01 00:00:00

  • Ancylostoma caninum: calibration and comparison of diagnostic accuracy of flotation in tube, McMaster and FLOTAC in faecal samples of dogs.

    abstract::We performed a calibration of flotation in tube, McMaster and FLOTAC to determine the optimal flotation solution (FS) and the influence of faecal preservation for the diagnosis of Ancylostoma caninum in dogs, and compared the accuracy of the three copromicroscopic techniques. Among nine different FS, sodium chloride a...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2011.01.014

    authors: Cringoli G,Rinaldi L,Maurelli MP,Morgoglione ME,Musella V,Utzinger J

    更新日期:2011-05-01 00:00:00

  • Steinernema carpocapsae DD136: metabolites limit the non-self adhesion responses of haemocytes of two lepidopteran larvae, Galleria mellonella (F. Pyralidae) and Malacosoma disstria (F. Lasiocampidae).

    abstract::Live adult and juvenile entomopathogenic Steinernema carpocapsae DD136 (P. Nematoda) were not subjected to adhesion by haemocytes of lepidopteran insect larvae of Galleria mellonella or Malacosoma disstriain vitro or in vivo. In vitro freeze-killed nematodes exhibited haemocyte attachment, the intensity increasing wit...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2008.07.001

    authors: Walter TN,Dunphy GB,Mandato CA

    更新日期:2008-10-01 00:00:00

  • Concordance of Giardia duodenalis assemblages determined by different PCR methodologies in three observational studies in Cuba.

    abstract::Giardia duodenalis is one of the most important intestinal parasites globally, especially in children, and in Cuba is the leading cause of chronic paediatric diarrhoea in this population. G. duodenalis is composed of eight genetic groups (or assemblages), two of which (A and B) are apparently zoonotic, occurring in bo...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2019.107814

    authors: Jerez Puebla LE,Núñez Fernández FA,Fraga J,Rivero LR,Millán IA,Valdés LA,Silva IM,Müller N,Robertson LJ

    更新日期:2020-02-01 00:00:00

  • Distinct characteristics of two intestinal protein compartments discriminated by using fenbendazole and a benzimidazole resistant isolate of Haemonchus contortus.

    abstract::The intestine of Haemonchus contortus is hypersensitive to the effects of the anthelmintic fenbendazole (FBZ). The effects are postulated to stem from disruption of microtubules and interference with apical secretory vesicle transport, followed by release of digestive enzymes into the intestinal cell cytoplasm. Here, ...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/s0014-4894(02)00135-2

    authors: Shompole S,Yao C,Cheng X,Knox D,Johnson S,Jasmer DP

    更新日期:2002-08-01 00:00:00

  • Schistosoma mansoni: long-term maintenance of clones by microsurgical transplantation of sporocysts.

    abstract::Schistosoma mansoni sporocysts originally derived from monomiracidially infected Biomphalaria glabrata snails were serially transplanted into the cephalopedal sinus of anesthetized snails by the microsurgical implantation of fragments of parasitized hepatopancreas and ovotestis. Three to six passages each of five male...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/0014-4894(84)90056-0

    authors: Cohen LM,Eveland LK

    更新日期:1984-02-01 00:00:00