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Schistosoma mansoni: peritoneal plasmacytogenesis and polypoid transformation of mesenteric milky spots in infected mice.

Abstract：

:We have studied inflammatory reactions in the mesenteric tissue of mice infected with Schistosoma mansoni. Perivascular tissue contained diffuse infiltrates of macrophages, eosinophilic granulocytes and lymphocytes. Angiogenesis in the perivascular adipose tissue was associated with superficial plasmacytogenic foci. Polypoid structures were occasionally formed adjacent to inflammatory foci in the adipose tissue, organized around loops of capillaries, with terminal formation of a glomerular capillary network embedded in connective tissue, covered by plasmacytes. We conclude that these structures are specialized milky spots dedicated to active plasmacytogenesis and antibody secretion into the peritoneal cavity of schistosome-infected mice.

journal_name

Exp Parasitol

journal_title

Experimental parasitology

authors

Weinberg DF,Baldo-Correa E,Lenzi HL,Borojevic R

doi

10.1016/0014-4894(92)90203-m

keywords:

subject

Has Abstract

pub_date

1992-06-01 00:00:00

pages

408-16

issue

4

eissn

0014-4894

issn

1090-2449

journal_volume

74

pub_type

杂志文章

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