Abstract:
:The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse resources that are optimized to study the actions of isolated genetic loci on a fixed background are less effective for studying intact polygenic networks and interactions among genes, environments, pathogens and other factors. The Collaborative Cross will provide a common reference panel specifically designed for the integrative analysis of complex systems and will change the way we approach human health and disease.
journal_name
Nat Genetjournal_title
Nature geneticsauthors
Churchill GA,Airey DC,Allayee H,Angel JM,Attie AD,Beatty J,Beavis WD,Belknap JK,Bennett B,Berrettini W,Bleich A,Bogue M,Broman KW,Buck KJ,Buckler E,Burmeister M,Chesler EJ,Cheverud JM,Clapcote S,Cook MN,Cox RD,Cdoi
10.1038/ng1104-1133keywords:
subject
Has Abstractpub_date
2004-11-01 00:00:00pages
1133-7issue
11eissn
1061-4036issn
1546-1718pii
ng1104-1133journal_volume
36pub_type
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