Abstract：
:A substantial and still growing body of research tries to link different psychological models and chronic diseases, with special emphasis on cardiovascular disease. These efforts have established several conceptual bridges that connect psychological alterations and psychosocial factors to the risks, onset and prognosis of cardiovascular disease. However, several different models have been suggested. Depression and learned helplessness are two central psychological models that have been shown to have major explanatory power in the development of chronic diseases. In this respect the so called Central-Eastern European health paradox, that is the morbidity and mortality crisis in these transforming societies can be regarded as a special experimental model. In this review chronic stress is proposed as an integrating theory that can be applied to different psychological models. Chronic stress and allostatic load has been shown to lead to typical pathogenetic results in animal experiments. Chronic stress theory is applicable to the explanation of the suddenly changing patterns of premature mortality rates in transforming societies. Literature and the different models in the field of psychology, behavioural sciences, and epidemiology are reviewed in terms of the chronic stress theory. The applicability of these results are investigated for further research, clinical and policy implications.
journal_name
Brain Res Bulljournal_title
Brain research bulletinauthors
Kopp MS,Réthelyi Jdoi
10.1016/j.brainresbull.2003.12.001keywords:
subject
Has Abstractpub_date
2004-02-01 00:00:00pages
351-67issue
5eissn
0361-9230issn
1873-2747pii
S0361923003003228journal_volume
62pub_type
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pub_type： 杂志文章
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