Interleukin-33 reduces neuronal damage and white matter injury via selective microglia M2 polarization after intracerebral hemorrhage in rats.

abstract：:In vitro and in vivo studies have demonstrated that lithium treatment can protect neurons against excitotoxic and ischemic damage. Yet the possible beneficial effect of chronic low dose lithium on a model of traumatic brain injury (TBI) has not been intensively investigated. In this study, lithium (1 mmol/kg) was give...

journal_title：Brain research bulletin

authors： Zhu ZF,Wang QG,Han BJ,William CP

更新日期：2010-10-30 00:00:00

abstract：:Since the second decade of this century it has been known that opiates can influence ingestive behaviors. Generally, opioid agents enhance feeding and opioid antagonists decrease feeding. The present paper reviews the responsiveness of different animal species to opiates in relation to ingestive behaviors, the opioid ...

journal_title：Brain research bulletin

authors： Levine AS,Morley JE,Gosnell BA,Billington CJ,Bartness TJ

更新日期：1985-06-01 00:00:00

abstract：:Changes in dietary habits, including the increased consumption of processed foods, rich in trans fatty acids (TFA), have profound effects on offspring health in later life. Thus, this study aimed to assess the influence of maternal trans fat intake during pregnancy or lactation on anxiety behavior, as well as markers ...

journal_title：Brain research bulletin

authors： Pase CS,Metz VG,Roversi K,Roversi K,Vey LT,Dias VT,Schons CF,de David Antoniazzi CT,Duarte T,Duarte M,Burger ME

更新日期：2021-01-01 00:00:00

abstract：:Groups of male Sprague-Dawley rats were predominantly fed either a high-fat or a high-carbohydrate (CHO) diet. For designated 2-day periods, their diets were switched. After baseline measurements of food and water intake, the rats were made diabetic by injections of either 40 or 46-50 mg/kg streptozotocin. Food and wa...

journal_title：Brain research bulletin

authors： Koopmans HS,Xavier Pi-Sunyer F

更新日期：1986-12-01 00:00:00

abstract：:Comparison of detailed physiological and morphological data shows that the hypothalamic aggression region in the rat largely coincides with the intermediate hypothalamic area. This region has a neuronal density of about 35.10(3) neurons per mm3, a synaptic density of about 300.10(6) per mm3, and a synapse to neuron ra...

journal_title：Brain research bulletin

authors： Aalders TT,Meek J

更新日期：1993-01-01 00:00:00

abstract：:Intracerebral hemorrhage (ICH) is a devastating form of stroke leading to a high rate of death and disability worldwide. Although it has been hypothesized that much of the IHC insult occurs in the subacute period mediated via a series of complex pathophysiological cascades, the molecular mechanisms involved in ICH hav...

journal_title：Brain research bulletin

authors： Ren C,Guingab-Cagmat J,Kobeissy F,Zoltewicz S,Mondello S,Gao M,Hafeez A,Li N,Geng X,Larner SF,Anagli J,Hayes RL,Ji X,Ding Y

更新日期：2014-03-01 00:00:00

abstract：:We report results of chromatographic, pH titration and nuclear magnetic resonance (NMR) spectroscopy studies demonstrating that the bovine pineal antireproductive tripeptide, Thr-Ser-Lys (BPART), binds to luteinizing hormone-releasing hormone (LHRH) at a site comprised of LHRH 2-5 (His-Trp-Ser-Tyr). BPART and LHRH hav...

journal_title：Brain research bulletin

authors： Root-Bernstein RS,Westall FC

更新日期：1986-10-01 00:00:00

abstract：:Spinocerebellar ataxia type 2 is caused by a polyglutamine stretch in the protein ataxin-2 that is due to an expansion of a CAG repeat in the spinocerebellar ataxia-2 gene. The function of wild-type ataxin-2 has not been clarified. A widespread distribution of this protein throughout the brain has been reported. We ex...

journal_title：Brain research bulletin

authors： Fusco FR,Viscomi MT,Bernardi G,Molinari M

更新日期：2001-10-01 00:00:00

abstract：:Neurochemical analysis of norepinephrine and serotonin with high performance liquid chromatography with electrochemical detection (LCEC) in several microdissected central autonomic nuclei of 4 week old and 16 week old spontaneously hypertensive rats (SHR), normotensive Wistar-Kyoto rats (WKY), and control normotensive...

journal_title：Brain research bulletin

authors： Felten SY,Weyhenmeyer JA,Felten DL

更新日期：1984-09-01 00:00:00

abstract：:The aim of this magnetic resonance imaging study was to find a geometrical characterization of the deeper part of the corpus callosum. Its shape was studied in 12 middle-aged persons free of white matter pathology. Profiles of curvatures were measured showing that this surface was close to a minimal one, especially at...

journal_title：Brain research bulletin

authors： Stievenart JL,Iba-Zizen MT,Tourbah A,Lopez A,Thibierge M,Abanou A,Cabanis EA

更新日期：1997-01-01 00:00:00

abstract：:Bone marrow mesenchymal stem cells (BMSCs) are involved in cancer initiation and metastasis, and sometimes mediate cell communication by releasing exosomes and delivering microRNAs (miRNAs). The study aims to investigate the effects of exosomal hsa-miR-23b-3p derived from human BMSCs on intracranial aneurysm (IA). Fir...

journal_title：Brain research bulletin

authors： Sun X,Zheng X,Zhang X,Zhang Y,Luo G

更新日期：2020-12-01 00:00:00

abstract：:Simultaneous blood and cerebrospinal fluid (CSF) samples were taken from conscious sheep before, during and after parturition. Concentrations of plasma and CSF oxytocin were significantly elevated during contractions and particularly at birth. Mean prepartum CSF concentrations of oxytocin were around 55% of those foun...

journal_title：Brain research bulletin

authors： Kendrick KM,Keverne EB,Hinton MR,Goode JA

更新日期：1991-05-01 00:00:00

abstract：:The changes of characteristics of dopamine (D1 and D2) and muscarinic receptors after acute and subacute administration of bicuculline were examined in rat brain. The results demonstrated that in striatal region, the Bmax of D2 receptor was significantly increased with no change of affinity after subacute administrati...

journal_title：Brain research bulletin

authors： Lim DK,Ito Y,Hoskins B,Ho IK

更新日期：1988-07-01 00:00:00

abstract：:Hoe 065 is a compound structurally related to the angiotensin converting enzyme inhibitors and capable of increasing central cholinergic activity. The effects of this compound were studied on alcohol intake and on the reduction in alcohol intake produced by abutapril, an angiotensin converting enzyme inhibitor. Hoe 06...

journal_title：Brain research bulletin

authors： Grupp LA,Chow SY

更新日期：1991-04-01 00:00:00

abstract：:A simple low-cost modification to a conventional horizontal two-stage micropipette puller is described. It allows the production of pipettes suitable for patch-clamp studies. It requires that the hard-pull stage of the fabrication process be disabled and two heating cycles, each with a different heating filament tempe...

journal_title：Brain research bulletin

authors： Mealing GA,Schwartz JL

更新日期：1989-05-01 00:00:00

abstract：:A high correlation between alcohol use and smoking has long been suggested by epidemiological data. We examined the potential behavioral interactions between ethanol and nicotine using ethanol-induced motor incoordination as the test response in mice. Effect of pretreatment of various doses of (-)-nicotine, (-)-cotini...

journal_title：Brain research bulletin

authors： Dar MS,Li C,Bowman ER

更新日期：1993-01-01 00:00:00

abstract：:The acute effects of 2-deoxy-D-glucose (2-DG)-induced glucoprivic feeding on the anorectic drug recognition site and Na+K(+)-ATPase in the brain were examined in adult rats and in lean and genetically obese mice. The marked hyperglycemia and the induction of feeding caused by the administration of 2-DG to satiated rat...

journal_title：Brain research bulletin

authors： Angel I,Hauger RL,Giblin BA,Paul SM

更新日期：1992-02-01 00:00:00

abstract：:It has been shown that during physiological stimuli, such as dehydration, supraoptic nucleus (SON) neurons undergo profound morphological changes. However, little is known about how much each type of cell, oxytocin (OT) or vasopressin (VP), contributes to this plasticity during dehydration. Using postembedding immunog...

journal_title：Brain research bulletin

authors： Marzban F,Tweedle CD,Hatton GI

更新日期：1992-05-01 00:00:00

abstract：:Serotonergic modulation of acetylcholine (ACh) release after neuron-specific increase of the expression of 5-HT(1B) receptors by gene transfer was studied in vitro and in vivo. The increased expression of the 5-HT(1B) receptor in vitro was induced by treating rat primary fetal septal cell cultures for 3 days with a vi...

journal_title：Brain research bulletin

authors： Riegert C,Rothmaier AK,Leemhuis J,Sexton TJ,Neumaier JF,Cassel JC,Jackisch R

更新日期：2008-07-01 00:00:00

abstract：:Three sets of experiments have been conducted that suggest that adrenal glucocorticoids play a role in the long-term control of intake and in dietary preferences. First, obesity is dependent upon glucocorticoid-modulated metabolic pathways. Surgical or pharmacological manipulations in obese animals that eliminate or d...

journal_title：Brain research bulletin

authors： Castonguay TW

更新日期：1991-09-01 00:00:00

abstract：:Our previous in vivo structure-activity studies suggested that the putative receptors mediating the effects of NPY and NPY2-36 on food intake and body temperature are pharmacologically different [17]. In the present study, we examined and compared dose-related effects of NPY and NPY2-36 on ad lib food intake and recta...

journal_title：Brain research bulletin

authors： Bouali SM,Fournier A,St-Pierre S,Jolicoeur FB

更新日期：1995-01-01 00:00:00

abstract：:A classical approach to the control of food consumption has been to assume separate mechanisms for the arousal to eat, on the one hand, and the satiation of feeding responses, on the other. The present paper is concerned with a single, and a comparatively simple, neuronal mechanism which is endowed with properties to ...

journal_title：Brain research bulletin

authors： Cooper SJ

更新日期：1985-10-01 00:00:00

abstract：:In this study we investigated the ability of the dentate gyrus to independently generate cholinergically induced theta rhythm in vitro. Two different experiments were performed. In Experiment I, new laminar profiles of theta phase, amplitude, and current sources and sinks were constructed. In this experiment a gradual...

journal_title：Brain research bulletin

authors： Kowalczyk T,Gołebiewski H,Konopacki J

更新日期：2009-09-28 00:00:00

abstract：:Accumulating evidence points to the amyloid-β (Aβ) peptide as the culprit in the pathogenesis of Alzheimer's disease (AD). β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1) is a protease that is responsible for initiating Aβ production. Although precise mechanisms that trigger Aβ accumulation remain unc...

journal_title：Brain research bulletin

authors： Ohno M

更新日期：2016-09-01 00:00:00

abstract：:Previous studies reported afferents to LC from the nucleus tractus solitarius (NTS), while more recent anatomic experiments indicate that the area of the nucleus prepositus hypoglossi (PrH), but not the NTS, provides robust innervation of LC. In the present experiments, the contribution of these two dorsomedial medull...

journal_title：Brain research bulletin

authors： Ennis M,Aston-Jones G

更新日期：1989-05-01 00:00:00

abstract：:Endogenous opioids (EO) probably do not modulate endotoxin (LPS)- or interleukin 1 (IL1)-induced fever because naloxone does not prevent its development. Yet, increases in CSF and hypothalamic levels of beta-endorphin have been reported during LPS-and IL1-induced fevers. Since IL1 also reduces the specific binding of ...

journal_title：Brain research bulletin

authors： Ahokas RA,Seydoux J,Llanos-Q J,Mashburn TA Jr,Blatteis CM

更新日期：1985-12-01 00:00:00

abstract：:Bacillus Calmette-Guérin (BCG) is administered to neonates worldwide, but it is still unknown whether this neonatal vaccination affects brain development during early postnatal life, despite the close association of the immune system with the brain. Newborn C57BL/6 mice were injected subcutaneously with BCG or phospha...

journal_title：Brain research bulletin

authors： Yang J,Qi F,Gu H,Zou J,Yang Y,Yuan Q,Yao Z

更新日期：2016-01-01 00:00:00

abstract：:Obesity and consumption of diet rich in fat are known to contribute to the development of Alzheimer's disease (AD) which is a complex and multifactorial neurodegenerative disease and a leading cause of mortality with unmet medical needs. Hypercholesterolemia was discovered to increase neuropathological changes along w...

journal_title：Brain research bulletin

authors： Zameer S,Alam M,Hussain S,Vohora D,Ali J,Najmi AK,Akhtar M

更新日期：2020-08-01 00:00:00

abstract：:The Tac4 gene-derived hemokinin-1 (HK-1) is present in pain-related regions and activates the tachykinin NK1 receptor, but with binding site and signaling pathways different from Substance P (SP). NK1 receptor is involved in nociception, but our earlier data showed that it has no role in chronic neuropathic hyperalges...

journal_title：Brain research bulletin

authors： Hunyady Á,Hajna Z,Gubányi T,Scheich B,Kemény Á,Gaszner B,Borbély É,Helyes Z

更新日期：2019-04-01 00:00:00

abstract：:After spinal cord injury (SCI) of the cat or rat neuronal centres below the level of lesion exhibit plasticity that can be exploited by specific training paradigms. In individuals with complete or incomplete SCI, human spinal locomotor centers can be activated by appropriate afferent input. This includes to facilitate...

journal_title：Brain research bulletin

authors： Dietz V

更新日期：2009-01-15 00:00:00