Medical genetics: a marker for Stevens-Johnson syndrome.

abstract：:Infertility resulting from a severe defect in sperm production affects 2% of men worldwide. Of these men with azoospermia, the absence of sperm in semen, one in eight carry de novo deletions for a specific region of the Y chromosome. A candidate gene for the Y-chromosome azoospermia factor (AZF) has been identified an...

journal_title：Nature

authors： Eberhart CG,Maines JZ,Wasserman SA

更新日期：1996-06-27 00:00:00

abstract：:The intracellular free Ca2+ ([Ca2+]i) regulates the K+ conductance (GK) of the many types of cell membrane. The Ca2+ influx during an action potential activates this [Ca2+]i-linked GK in most neurones. In caffeine-treated sympathetic ganglion cells, however, Ca2+ released from an intracellular Ca2+ reservoir site anal...

journal_title：Nature

authors： Morita K,Koketsu K,Kuba K

更新日期：1980-01-10 00:00:00

abstract：:The limited ranges of the wild progenitors of many of the primary European domestic species point to their origins further east in Anatolia or the fertile crescent. The wild ox (Bos primigenius), however, ranged widely and it is unknown whether it was domesticated within Europe as one feature of a local contribution t...

journal_title：Nature

authors： Troy CS,MacHugh DE,Bailey JF,Magee DA,Loftus RT,Cunningham P,Chamberlain AT,Sykes BC,Bradley DG

更新日期：2001-04-26 00:00:00

abstract：:Schistosoma japonicum is a parasitic flatworm that causes human schistosomiasis, which is a significant cause of morbidity in China and the Philippines. Here we present a draft genomic sequence for the worm. The genome provides a global insight into the molecular architecture and host interaction of this complex metaz...

journal_title：Nature

authors： Schistosoma japonicum Genome Sequencing and Functional Analysis Consortium.

更新日期：2009-07-16 00:00:00

abstract：:The origin of cooperation is a central challenge to our understanding of evolution. The fact that microbial interactions can be manipulated in ways that animal interactions cannot has led to a growing interest in microbial models of cooperation and competition. For the budding yeast Saccharomyces cerevisiae to grow on...

journal_title：Nature

authors： Gore J,Youk H,van Oudenaarden A

更新日期：2009-05-14 00:00:00

abstract：:The growth of plants depends on continuous function of the meristems. Shoot meristems are responsible for all the post-embryonic aerial organs, such as leaves, stems and flowers. It has been assumed that the phytohormone cytokinin has a positive role in shoot meristem function. A severe reduction in the size of merist...

journal_title：Nature

authors： Kurakawa T,Ueda N,Maekawa M,Kobayashi K,Kojima M,Nagato Y,Sakakibara H,Kyozuka J

更新日期：2007-02-08 00:00:00

abstract：:alpha-Neurotoxins bind to cholinergic receptor, block transmission, and induce sprouting of retinal terminals in the toad tectum. New connections retain an orderliness that suggests a selective affinity between presynaptic terminals. The results suggest that postsynaptic cells exert a control, associated with receptor...

journal_title：Nature

authors： Freeman JA

更新日期：1977-09-15 00:00:00

abstract：:Organic photovoltaic cells are now approaching commercially viable efficiencies, particularly for applications that make use of their unique potential for flexibility and semitransparency1-3. However, their reliability remains a major concern, as even the most stable devices reported so far degrade within only a few y...

journal_title：Nature

authors： Burlingame Q,Huang X,Liu X,Jeong C,Coburn C,Forrest SR

更新日期：2019-09-01 00:00:00

abstract：:Most of what is known about the evolution of deinonychosaurs (that is, the group of theropods most closely related to birds) is based on discoveries from North America and Asia. Except for Unenlagia comahuensis and some fragmentary remains from northern Africa, no other evidence was available on deinonychosaurian dive...

journal_title：Nature

authors： Novas FE,Pol D

更新日期：2005-02-24 00:00:00

abstract：:The development of a eutherian mammal as a male is a consequence of testis formation in the embryo, which is thought to be initiated by a gene on the Y chromosome. In the absence of this gene, ovaries are formed and female characteristics develop. Sex determination therefore hinges on the action of this testis-determi...

journal_title：Nature

authors： Koopman P,Münsterberg A,Capel B,Vivian N,Lovell-Badge R

更新日期：1990-11-29 00:00:00

abstract：:What limits the rate at which sensory information can be transmitted across synaptic connections in the brain? High-frequency signalling is restricted to brief bursts at many central excitatory synapses, whereas graded ribbon-type synapses can sustain release and transmit information at high rates. Here we investigate...

journal_title：Nature

authors： Saviane C,Silver RA

更新日期：2006-02-23 00:00:00

abstract：:The Kyoto Protocol permits countries to meet part of their emission reduction obligations by cutting back on gases other than CO2 (ref. 1). This approach requires a definition of trade-offs among the radiatively active gases. The Intergovernmental Panel on Climate Change has suggested global warming potentials for thi...

journal_title：Nature

authors： Manne AS,Richels RG

更新日期：2001-04-05 00:00:00

abstract：:oop RNA, which is initiated at the po promoter and is 81 nucleotides long, can function as a leader sequence for the lambda immunity establishment transcription, previously believed to originate at a special promoter pre located in the y region. Thus, oop RNA seems to have a dual role, either favouring the lytic cycle...

journal_title：Nature

authors： Honigman A,Hu SL,Chase R,Szybalski W

更新日期：1976-07-08 00:00:00

abstract：:Plant respiration results in an annual flux of carbon dioxide (CO2) to the atmosphere that is six times as large as that due to the emissions from fossil fuel burning, so changes in either will impact future climate. As plant respiration responds positively to temperature, a warming world may result in additional resp...

journal_title：Nature

authors： Reich PB,Sendall KM,Stefanski A,Wei X,Rich RL,Montgomery RA

更新日期：2016-03-31 00:00:00

abstract：:The basolateral amygdala (BLA) has a crucial role in emotional learning irrespective of valence. The BLA projection to the nucleus accumbens (NAc) is thought to modulate cue-triggered motivated behaviours, but our understanding of the interaction between these two brain regions has been limited by the inability to man...

journal_title：Nature

authors： Stuber GD,Sparta DR,Stamatakis AM,van Leeuwen WA,Hardjoprajitno JE,Cho S,Tye KM,Kempadoo KA,Zhang F,Deisseroth K,Bonci A

更新日期：2011-06-29 00:00:00

abstract：:Magnetic interactions and magnetic impurities are destructive to superconductivity in conventional superconductors. By contrast, in some unconventional macroscopic quantum systems (such as superfluid 3He and superconducting UGe2), the superconductivity (or superfluidity) is actually mediated by magnetic interactions. ...

journal_title：Nature

authors： Hudson EW,Lang KM,Madhavan V,Pan SH,Eisaki H,Uchida S,Davis JC

更新日期：2001-06-21 00:00:00

abstract：:The c-Myc oncoprotein promotes proliferation and apoptosis, such that mutations that disable apoptotic programmes often cooperate with MYC during tumorigenesis. Here we report that two common mutant MYC alleles derived from human Burkitt's lymphoma uncouple proliferation from apoptosis and, as a result, are more effec...

journal_title：Nature

authors： Hemann MT,Bric A,Teruya-Feldstein J,Herbst A,Nilsson JA,Cordon-Cardo C,Cleveland JL,Tansey WP,Lowe SW

更新日期：2005-08-11 00:00:00

abstract：:Chameleons are arboral lizards that spot their prey visually and catch it by highly precise shots with their long sticky tongue. They scan their environment by large-amplitude independent saccadic eye movements; once an insect is detected, the head axis is aligned towards the target ('head tracking', both eyes come fo...

journal_title：Nature

authors： Ott M,Schaeffel F

更新日期：1995-02-23 00:00:00

abstract：:Medawar has suggested that the major histocompatibility gene complex (MHC) might be involved in the contact inhibition of movement shown by fibroblasts and epithelia. Contact inhibition of movement is that reaction of cells which stops the movement of one cell over another and thus leads to monolayering and other feat...

journal_title：Nature

authors： Curtis AS,Rooney P

更新日期：1979-09-20 00:00:00

abstract：:Mecsas and colleagues suggest that a deficiency in the chemokine receptor CCR5 in humans is unlikely to confer protection against plague, based on their study of Yersinia pestis infection in Ccr5-deficient mice. They were testing the hypothesis that a mutation in the CCR5 gene, frequently found in Caucasians, may have...

journal_title：Nature

authors： Elvin SJ,Williamson ED,Scott JC,Smith JN,Pérez De Lema G,Chilla S,Clapham P,Pfeffer K,Schlöndorff D,Luckow B

更新日期：2004-07-22 00:00:00

abstract：:Three subfamilies of grasses, the Ehrhartoideae, Panicoideae and Pooideae, provide the bulk of human nutrition and are poised to become major sources of renewable energy. Here we describe the genome sequence of the wild grass Brachypodium distachyon (Brachypodium), which is, to our knowledge, the first member of the P...

journal_title：Nature

authors： International Brachypodium Initiative.

更新日期：2010-02-11 00:00:00

abstract：:The most unique feature of Earth is the existence of life, and the most extraordinary feature of life is its diversity. Approximately 9 million types of plants, animals, protists and fungi inhabit the Earth. So, too, do 7 billion people. Two decades ago, at the first Earth Summit, the vast majority of the world's nati...

journal_title：Nature

authors： Cardinale BJ,Duffy JE,Gonzalez A,Hooper DU,Perrings C,Venail P,Narwani A,Mace GM,Tilman D,Wardle DA,Kinzig AP,Daily GC,Loreau M,Grace JB,Larigauderie A,Srivastava DS,Naeem S

更新日期：2012-06-06 00:00:00

abstract：:Locomotion relies on neural networks called central pattern generators (CPGs) that generate periodic motor commands for rhythmic movements. In vertebrates, the excitatory synaptic drive for inducing the spinal CPG can originate from either supraspinal glutamatergic inputs or from within the spinal cord. Here we identi...

journal_title：Nature

authors： Wyart C,Del Bene F,Warp E,Scott EK,Trauner D,Baier H,Isacoff EY

更新日期：2009-09-17 00:00:00

abstract：:Mammals owe part of their evolutionary success to the harmonious exchanges of information, energy and immunity between females and their offspring. This functional reciprocity is vital for the survival and normal development of infants, and for the inclusive fitness of parents. It is best seen in the intense exchanges...

journal_title：Nature

authors： Schaal B,Coureaud G,Langlois D,Giniès C,Sémon E,Perrier G

更新日期：2003-07-03 00:00:00

abstract：:Protein engineering is being developed for mapping the energetics and pathway of protein folding. From kinetic studies on wild-type and mutant proteins, the sequence and energetics of formation of tertiary interactions of side chains can be mapped and the formation of secondary structure inferred. Here we cross-check ...

journal_title：Nature

authors： Bycroft M,Matouschek A,Kellis JT Jr,Serrano L,Fersht AR

更新日期：1990-08-02 00:00:00

abstract：:During platelet activation there is a major reorganization in the platelet cytoskeleton that accompanies a rapid change in platelet shape. Many of the events associated with activation are attributed to a rise in calcium concentration within the platelet cytoplasm. One direct consequence of the elevated calcium is the...

journal_title：Nature

authors： O'Halloran T,Beckerle MC,Burridge K

更新日期：1985-10-03 00:00:00

abstract：:Therapeutic vaccines derived from carbohydrate antigen-adjuvant combinations are a promising approach for cancer immunotherapy. One of the critical limitations in this area is access to sufficient quantities of tumour-associated carbohydrate antigens and glycoconjugate adjuvants. At present, availability of the comple...

journal_title：Nature

authors： Galonić DP,Gin DY

更新日期：2007-04-26 00:00:00

abstract：:Hunter-Schreger bands (HSB) are seen in teeth that are composed of crossed sets of enamel prisms. They are present in the teeth of man and many other mammals, but absent in most insectivores and multituberculates. It has been suggested that the presence of HSB makes the tooth enamel less likely to split and is associa...

journal_title：Nature

authors： von Koenigswald W,Rensberger JM,Pretzschner HU

更新日期：1987-07-09 00:00:00

abstract：:Normal cellular function requires that organelles be positioned in specific locations. The direction in which molecular motors move organelles is based in part on the polarity of microtubules and actin filaments. However, this alone does not determine the intracellular destination of organelles. For example, the yeast...

journal_title：Nature

authors： Tang F,Kauffman EJ,Novak JL,Nau JJ,Catlett NL,Weisman LS

更新日期：2003-03-06 00:00:00

abstract：:An alphabeta T-cell response depends on the recognition of antigen plus major histocompatibility complex (MHC) proteins by its antigen receptor (TCR). The ability of peripheral alphabeta T cells to recognize MHC is at least partly determined by MHC-dependent thymic selection, by which an immature T cell survives only ...

journal_title：Nature

authors： Scott-Browne JP,White J,Kappler JW,Gapin L,Marrack P

更新日期：2009-04-23 00:00:00