Chemical and behavioural characterization of the rabbit mammary pheromone.

Abstract:

:Mammals owe part of their evolutionary success to the harmonious exchanges of information, energy and immunity between females and their offspring. This functional reciprocity is vital for the survival and normal development of infants, and for the inclusive fitness of parents. It is best seen in the intense exchanges taking place around the mother's offering of, and the infant's quest for, milk. All mammalian females have evolved behavioural and sensory methods of stimulating and guiding their inexperienced newborns to their mammae, whereas newborns have coevolved means to respond to them efficiently. Among these cues, maternal odours have repeatedly been shown to be involved, but the chemical identity and pheromonal nature of these cues have not been definitively characterized until now. Here we focus on the nature of an odour signal emitted by the female rabbit to which newborn pups respond by attraction and oral grasping, and provide a complete chemical and behavioural description of a pheromone of mammary origin in a mammalian species.

journal_name

Nature

journal_title

Nature

authors

Schaal B,Coureaud G,Langlois D,Giniès C,Sémon E,Perrier G

doi

10.1038/nature01739

keywords:

subject

Has Abstract

pub_date

2003-07-03 00:00:00

pages

68-72

issue

6944

eissn

0028-0836

issn

1476-4687

pii

nature01739

journal_volume

424

pub_type

杂志文章

相关文献

NATURE文献大全
  • Transposable genetic elements and plasmid evolution.

    abstract::Transposable elements of DNA that are structurally defined and genetically discrete units seem to have an important role in the evolution of bacterial plasmids. Recombination occurring at the termini of such elements can result in the joining together of unrelated DNA segments that lack extensive nucleotide sequence h...

    journal_title:Nature

    pub_type: 杂志文章,评审

    doi:10.1038/263731a0

    authors: Cohen SN

    更新日期:1976-10-28 00:00:00

  • Cooperation and competition in pathogenic bacteria.

    abstract::Explaining altruistic cooperation is one of the greatest challenges for evolutionary biology. One solution to this problem is if costly cooperative behaviours are directed towards relatives. This idea of kin selection has been hugely influential and applied widely from microorganisms to vertebrates. However, a problem...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature02744

    authors: Griffin AS,West SA,Buckling A

    更新日期:2004-08-26 00:00:00

  • A new orang-utan relative from the Late Miocene of Thailand.

    abstract::The fossil record of the living great apes is poor. New fossils from undocumented areas, particularly the equatorial forested habitats of extant hominoids, are therefore crucial for understanding their origins and evolution. Two main competing hypotheses have been proposed for orang-utan origins: dental similarities s...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature02245

    authors: Chaimanee Y,Suteethorn V,Jintasakul P,Vidthayanon C,Marandat B,Jaeger JJ

    更新日期:2004-01-29 00:00:00

  • Oldest playable musical instruments found at Jiahu early Neolithic site in China.

    abstract::Excavations at the early Neolithic site of Jiahu in Henan Province, China have produced what may be the earliest complete, playable, tightly-dated multinote musical instruments. Jiahu was occupied from 7000 BC to 5700 BC, considerably antedating the well known Peiligang culture. Here we describe six exquisitely made c...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/43865

    authors: Zhang J,Harbottle G,Wang C,Kong Z

    更新日期:1999-09-23 00:00:00

  • The perception of heading during eye movements.

    abstract::When a person walks through a rigid environment while holding eyes and head fixed, the pattern of retinal motion flows radially away from a point, the focus of expansion (Fig. 1a). Under such conditions of translation, heading corresponds to the focus of expansion and people identify it readily. But when making an eye...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/360583a0

    authors: Royden CS,Banks MS,Crowell JA

    更新日期:1992-12-10 00:00:00

  • Beyond the standard model with the LHC.

    abstract::Whether or not the Large Hadron Collider reveals the long-awaited Higgs particle, it is likely to lead to discoveries that add to, or challenge, the standard model of particle physics. Data produced will be pored over for any evidence of supersymmetric partners for the existing denizens of the particle 'zoo' and for t...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature06079

    authors: Ellis J

    更新日期:2007-07-19 00:00:00

  • Neurons derived from radial glial cells establish radial units in neocortex.

    abstract::The neocortex of the adult brain consists of neurons and glia that are generated by precursor cells of the embryonic ventricular zone. In general, glia are generated after neurons during development, but radial glia are an exception to this rule. Radial glia are generated before neurogenesis and guide neuronal migrati...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/35055553

    authors: Noctor SC,Flint AC,Weissman TA,Dammerman RS,Kriegstein AR

    更新日期:2001-02-08 00:00:00

  • Angiogenesis in life, disease and medicine.

    abstract::The growth of blood vessels (a process known as angiogenesis) is essential for organ growth and repair. An imbalance in this process contributes to numerous malignant, inflammatory, ischaemic, infectious and immune disorders. Recently, the first anti-angiogenic agents have been approved for the treatment of cancer and...

    journal_title:Nature

    pub_type: 杂志文章,评审

    doi:10.1038/nature04478

    authors: Carmeliet P

    更新日期:2005-12-15 00:00:00

  • Absolute time-of-arrival measurements of optical pulses from the Crab pulsar.

    abstract::An attempt is made to understand the characteristics of pulsar slowdown in terms of various possible emission mechanisms. Though magnetic-dipole radiation seems to be dominant, the deviations from a pure dipolar decay are large compared with errors in measurement and indicate the presence of more complicated braking m...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/228445a0

    authors: Papaliolios C,Carleton NP,Horowitz P

    更新日期:1970-10-31 00:00:00

  • A monomeric insulin from the porcupine (Hystrix cristata), an Old World hystricomorph.

    abstract::The insulins of New World hystricomorph rodents exhibit many novel amino acid changes in primary structure when compared with other mammalian insulins. These changes give rise to unusual properties (low potency, failure to self-associate) not shared by other naturally-occurring insulins. We report here on the primary ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/286822a0

    authors: Horuk R,Blundell TL,Lazarus NR,Neville RW,Stone D,Wollmer A

    更新日期:1980-08-21 00:00:00

  • Spermiogenesis deficiency and germ-cell apoptosis in CREM-mutant mice.

    abstract::Spermiogenesis is a complex process by which postmeiotic male germ cells differentiate into mature spermatozoa. This process involves remarkable structural and biochemical changes including nuclear DNA compaction and acrosome formation. Transcription activator CREM (cyclic AMP-responsive element modulator) is highly e...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/380159a0

    authors: Nantel F,Monaco L,Foulkes NS,Masquilier D,LeMeur M,Henriksén K,Dierich A,Parvinen M,Sassone-Corsi P

    更新日期:1996-03-14 00:00:00

  • Messenger RNA for the coat protein of tobacco mosaic virus.

    abstract::TMV RNA is not an efficient template for translation of the viral coat protein, in spite of containing nucleotide sequences coding for the protein. Efficient translation requires the prior synthesis within infected cells of a smaller RNA carrying only a portion of the information encoded in the whole genome. ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/260759a0

    authors: Hunter TR,Hunt T,Knowland J,Zimmern D

    更新日期:1976-04-29 00:00:00

  • Antigen-induced B-cell death and elimination during germinal-centre immune responses.

    abstract::During an immune response, hypermutation of immunoglobulin genes in B cells proliferating within germinal centres (GCs) generates variant antibodies that react with higher affinity against either foreign or self antigens. Several experiments suggest that self-reactive B cells may be censored at this stage of the immun...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/375334a0

    authors: Shokat KM,Goodnow CC

    更新日期:1995-05-25 00:00:00

  • Unified response to bilateral hemispheric stimulation by a split-brain patient.

    abstract::Surgical sectioning of the corpus callosum in epileptic patients has provided a unique opportunity to study separately the competence and processing capacities of the two cerebral hemispheres, each of which is able to perceive, think, memorize and learn independently and essentially outside the realm of awareness of t...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/305800a0

    authors: Sergent J

    更新日期:1983-10-27 00:00:00

  • Vaccination against ovine cysticercosis using a defined recombinant antigen.

    abstract::Cysticercosis caused by larval tapeworms is a major public health problem and a cause of substantial economic losses in the farm-animal industries. Taenia ovis in sheep is a particularly important example. Immunity to reinfection with the larvae has a central role in regulating natural transmission of the parasites, a...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/338585a0

    authors: Johnson KS,Harrison GB,Lightowlers MW,O'Hoy KL,Cougle WG,Dempster RP,Lawrence SB,Vinton JG,Heath DD,Rickard MD

    更新日期:1989-04-13 00:00:00

  • Rapid and early export of Phaeocystis antarctica blooms in the Ross Sea, Antarctica.

    abstract::The Southern Ocean is very important for the potential sequestration of carbon dioxide in the oceans and is expected to be vulnerable to changes in carbon export forced by anthropogenic climate warming. Annual phytoplankton blooms in seasonal ice zones are highly productive and are thought to contribute significantly ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/35007061

    authors: DiTullio GR,Grebmeier JM,Arrigo KR,Lizotte MP,Robinson DH,Leventer A,Barry JP,VanWoert ML,Dunbar RB

    更新日期:2000-04-06 00:00:00

  • Electrophoretic movement and localisation of acetylcholine receptors in the embryonic muscle cell membrane.

    abstract::A steady electric field of 30 mV across a single embryonic muscle cell produces accumulation of acetylcholine receptors toward one pole of the cell within 1 h. The movement is electrophoretic in nature and the accumulation results in the formation of stable, metabolically independent receptor aggregates. ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/275031a0

    authors: Orida N,Poo MM

    更新日期:1978-09-07 00:00:00

  • Laser-plasma acceleration of quasi-monoenergetic protons from microstructured targets.

    abstract::Particle acceleration based on high intensity laser systems (a process known as laser-plasma acceleration) has achieved high quality particle beams that compare favourably with conventional acceleration techniques in terms of emittance, brightness and pulse duration. A long-term difficulty associated with laser-plasma...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature04492

    authors: Schwoerer H,Pfotenhauer S,Jäckel O,Amthor KU,Liesfeld B,Ziegler W,Sauerbrey R,Ledingham KW,Esirkepov T

    更新日期:2006-01-26 00:00:00

  • Specific dephosphorylation of membrane proteins in Rous sarcoma virus-transformed chick embryo fibroblasts.

    abstract::Chick embryo fibroblasts (CEF) infected with avian sarcoma virus become rapidly transformed as a result of expression of the viral src gene in the form of a single polypeptide of molecular weight 60,000 (pp60src) with protein kinase activity and suggested preferential association with the plasma membrane. Studies with...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/287241a0

    authors: Witt DP,Gordon JA

    更新日期:1980-09-18 00:00:00

  • Coral mucus functions as an energy carrier and particle trap in the reef ecosystem.

    abstract::Zooxanthellae, endosymbiotic algae of reef-building corals, substantially contribute to the high gross primary production of coral reefs, but corals exude up to half of the carbon assimilated by their zooxanthellae as mucus. Here we show that released coral mucus efficiently traps organic matter from the water column ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature02344

    authors: Wild C,Huettel M,Klueter A,Kremb SG,Rasheed MY,Jørgensen BB

    更新日期:2004-03-04 00:00:00

  • The Mg-chelatase H subunit is an abscisic acid receptor.

    abstract::Abscisic acid (ABA) is a vital phytohormone that regulates mainly stomatal aperture and seed development, but ABA receptors involved in these processes have yet to be determined. We previously identified from broad bean an ABA-binding protein (ABAR) potentially involved in stomatal signalling, the gene for which encod...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature05176

    authors: Shen YY,Wang XF,Wu FQ,Du SY,Cao Z,Shang Y,Wang XL,Peng CC,Yu XC,Zhu SY,Fan RC,Xu YH,Zhang DP

    更新日期:2006-10-19 00:00:00

  • Immunisation against heterologous type II collagen induces arthritis in mice.

    abstract::The induction of polyarthritis in rats by intradermal immunisation with homologous or heterologous type II collagen incomplete or incomplete Freund's adjuvant was reported recently by Trentham et al. We have now produced a similar disease in certain strains of mice. ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/283666a0

    authors: Courtenay JS,Dallman MJ,Dayan AD,Martin A,Mosedale B

    更新日期:1980-02-14 00:00:00

  • Tobacco smoking and somatic mutations in human bronchial epithelium.

    abstract::Tobacco smoking causes lung cancer1-3, a process that is driven by more than 60 carcinogens in cigarette smoke that directly damage and mutate DNA4,5. The profound effects of tobacco on the genome of lung cancer cells are well-documented6-10, but equivalent data for normal bronchial cells are lacking. Here we sequence...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/s41586-020-1961-1

    authors: Yoshida K,Gowers KHC,Lee-Six H,Chandrasekharan DP,Coorens T,Maughan EF,Beal K,Menzies A,Millar FR,Anderson E,Clarke SE,Pennycuick A,Thakrar RM,Butler CR,Kakiuchi N,Hirano T,Hynds RE,Stratton MR,Martincorena I,Janes

    更新日期:2020-02-01 00:00:00

  • Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism.

    abstract::Tissue-resident memory T (TRM) cells persist indefinitely in epithelial barrier tissues and protect the host against pathogens. However, the biological pathways that enable the long-term survival of TRM cells are obscure. Here we show that mouse CD8+ TRM cells generated by viral infection of the skin differentially ex...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature21379

    authors: Pan Y,Tian T,Park CO,Lofftus SY,Mei S,Liu X,Luo C,O'Malley JT,Gehad A,Teague JE,Divito SJ,Fuhlbrigge R,Puigserver P,Krueger JG,Hotamisligil GS,Clark RA,Kupper TS

    更新日期:2017-03-09 00:00:00

  • The C5a chemoattractant receptor mediates mucosal defence to infection.

    abstract::A family of G-protein-coupled chemoattractant receptors is known to mediate the transport and activation of neutrophils and macrophages This family includes receptors for chemokines, such as interleukin-8, bacterial formylated peptides, platelet-activating factor, leukotriene B4, and the complement anaphylatoxins. The...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/383086a0

    authors: Höpken UE,Lu B,Gerard NP,Gerard C

    更新日期:1996-09-05 00:00:00

  • HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product.

    abstract::Apart from the retroviral gag, pol and env the HIV genome contains the F (3' orf) gene which encodes a polypeptide of 206 amino acids which is myristylated at the N-terminal and whose function is unknown. We have expressed the F gene in Escherichia coli and from a recombinant vaccinia virus, VVTGfHIV. The F-protein pr...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/330266a0

    authors: Guy B,Kieny MP,Riviere Y,Le Peuch C,Dott K,Girard M,Montagnier L,Lecocq JP

    更新日期:1987-11-19 00:00:00

  • Folding at the speed limit.

    abstract::Many small proteins seem to fold by a simple process explicable by conventional chemical kinetics and transition-state theory. This assumes an instant equilibrium between reactants and a high-energy activated state. In reality, equilibration occurs on timescales dependent on the molecules involved, below which such an...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature01609

    authors: Yang WY,Gruebele M

    更新日期:2003-05-08 00:00:00

  • Ultraviolet emissions from the magnetic footprints of Io, Ganymede and Europa on Jupiter.

    abstract::Io leaves a magnetic footprint on Jupiter's upper atmosphere that appears as a spot of ultraviolet emission that remains fixed underneath Io as Jupiter rotates. The specific physical mechanisms responsible for generating those emissions are not well understood, but in general the spot seems to arise because of an elec...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/415997a

    authors: Clarke JT,Ajello J,Ballester G,Ben Jaffel L,Connerney J,Gérard JC,Gladstone GR,Grodent D,Pryor W,Trauger J,Waite JH Jr

    更新日期:2002-02-28 00:00:00

  • Location of a delta-subunit region determining ion transport through the acetylcholine receptor channel.

    abstract::The combination of complementary DNA expression and single-channel current analysis provides a powerful tool for studying the structure-function relationship of the nicotinic acetylcholine receptor (AChR) (refs 1-5). We have previously shown that AChR channels consisting of subunits from different species, expressed i...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/324670a0

    authors: Imoto K,Methfessel C,Sakmann B,Mishina M,Mori Y,Konno T,Fukuda K,Kurasaki M,Bujo H,Fujita Y

    更新日期:1986-12-18 00:00:00

  • Extensive variation of human immunodeficiency virus type-1 in vivo.

    abstract::Genotypic variation among independent isolates of human immunodeficiency virus type-1 (HIV-1) is well known, but its molecular basis and biological consequences are poorly understood. We examined the genesis of molecular variation in HIV-1 by sequential virus isolations from two chronically infected individuals and an...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/334440a0

    authors: Saag MS,Hahn BH,Gibbons J,Li Y,Parks ES,Parks WP,Shaw GM

    更新日期:1988-08-04 00:00:00