A new orang-utan relative from the Late Miocene of Thailand.

abstract：:The rapid development of the silk glands of Bombyx mori during the last larval instar shows two phases. During the first 4 days, in both the middle and posterior parts of the silk glands, the ribosomal machinery is assembled and the synthesis of housekeeping proteins starts. During the second phase (the last 4 days), ...

journal_title：Nature

authors： Hentzen D,Chevallier A,Garel JP

更新日期：1981-03-19 00:00:00

abstract：:Analogous to the progression of events in the opiate receptor-enkaphalin area, the first reports that benzodiazepines have selective and specific high-affinity binding sites in brain have stimulated a search for the endogenous 'ligand' or substance that might normally act at these sites. Braestrup and co-workers have ...

journal_title：Nature

authors： Tenen SS,Hirsch JD

更新日期：1980-12-11 00:00:00

abstract：:Aerobic methanotrophic bacteria consume methane as it diffuses away from methanogenic zones of soil and sediment. They act as a biofilter to reduce methane emissions to the atmosphere, and they are therefore targets in strategies to combat global climate change. No cultured methanotroph grows optimally below pH 5, but...

journal_title：Nature

authors： Dunfield PF,Yuryev A,Senin P,Smirnova AV,Stott MB,Hou S,Ly B,Saw JH,Zhou Z,Ren Y,Wang J,Mountain BW,Crowe MA,Weatherby TM,Bodelier PL,Liesack W,Feng L,Wang L,Alam M

更新日期：2007-12-06 00:00:00

abstract：:Recognition of self-antigen-derived epitopes presented by major histocompatibility complex class II (MHC II) molecules on thymic epithelial cells (TECs) is critical for the generation of a functional and self-tolerant CD4 T-cell repertoire. Whereas haematopoietic antigen-presenting cells generate MHC-II-peptide comple...

journal_title：Nature

authors： Nedjic J,Aichinger M,Emmerich J,Mizushima N,Klein L

更新日期：2008-09-18 00:00:00

abstract：:The loose material--regolith--on the surfaces of asteroids is thought to represent ballistically emplaced ejecta from impacts but the identification of source craters and the detailed study of the regolith modification have been hampered by the limited spatial resolution and area coverage of the few asteroids imaged b...

journal_title：Nature

authors： Thomas PC,Veverka J,Robinson MS,Murchie S

更新日期：2001-09-27 00:00:00

abstract：:The wavefunction is the complex distribution used to completely describe a quantum system, and is central to quantum theory. But despite its fundamental role, it is typically introduced as an abstract element of the theory with no explicit definition. Rather, physicists come to a working understanding of the wavefunct...

journal_title：Nature

authors： Lundeen JS,Sutherland B,Patel A,Stewart C,Bamber C

更新日期：2011-06-08 00:00:00

abstract：:Mammalian circadian clocks consist of complex integrated feedback loops that cannot be elucidated without comprehensive measurement of system dynamics and determination of network structures. To dissect such a complicated system, we took a systems-biological approach based on genomic, molecular and cell biological tec...

journal_title：Nature

authors： Ueda HR,Chen W,Adachi A,Wakamatsu H,Hayashi S,Takasugi T,Nagano M,Nakahama K,Suzuki Y,Sugano S,Iino M,Shigeyoshi Y,Hashimoto S

更新日期：2002-08-01 00:00:00

abstract：:Understanding the capacity of natural populations to adapt to their local environment is a central topic in evolutionary biology. Phenotypic differences between populations may have a genetic basis, but showing that they reflect different adaptive optima requires the quantification of both gene flow and selection. Goo...

journal_title：Nature

authors： Postma E,van Noordwijk AJ

更新日期：2005-01-06 00:00:00

abstract：:Homeostasis is a biological principle for regulation of essential physiological parameters within a set range. Behavioural responses due to deviation from homeostasis are critical for survival, but motivational processes engaged by physiological need states are incompletely understood. We examined motivational charact...

journal_title：Nature

authors： Betley JN,Xu S,Cao ZFH,Gong R,Magnus CJ,Yu Y,Sternson SM

更新日期：2015-05-14 00:00:00

abstract：:The upper temperature at which a living system can exist is limited by the hydrolytic breakdown rate of its chemical constituents. The peptide bonds of proteins, the phosphodiester and N-glycosyl bonds in RNA and DNA, and the pyrophosphate and N-glycosyl bonds in nucleotides such as ATP and NAD are among the more impo...

journal_title：Nature

authors： White RH

更新日期：1984-08-02 00:00:00

abstract：:Splicing of the Tetrahymena ribosomal intron was first studied by Cech et al., who subsequently demonstrated that the intron RNA catalyses its own excision from a primary transcript to yield mature ribosomal RNA. This intron shares several short conserved sequences and a common secondary structure with several other i...

journal_title：Nature

authors： Szostak JW

更新日期：1986-07-03 00:00:00

abstract：:Defining the functional relationships between proteins is critical for understanding virtually all aspects of cell biology. Large-scale identification of protein complexes has provided one important step towards this goal; however, even knowledge of the stoichiometry, affinity and lifetime of every protein-protein int...

journal_title：Nature

authors： Collins SR,Miller KM,Maas NL,Roguev A,Fillingham J,Chu CS,Schuldiner M,Gebbia M,Recht J,Shales M,Ding H,Xu H,Han J,Ingvarsdottir K,Cheng B,Andrews B,Boone C,Berger SL,Hieter P,Zhang Z,Brown GW,Ingles CJ,Emili

更新日期：2007-04-12 00:00:00

abstract：:We are in the enviable position of having two distinct drafts of the human genome sequence. Although gaps, errors, redundancy and incomplete annotation mean that individually each falls short of the ideal, many of these problems can be assessed by comparison. Here we present some comparative analyses of these drafts. ...

journal_title：Nature

authors： Aach J,Bulyk ML,Church GM,Comander J,Derti A,Shendure J

更新日期：2001-02-15 00:00:00

abstract：:Nerve growth factor (NGF) activity was not detected by bioassay in irides killed immediately after excision but NGF appeared within 24 h in living irides placed in culture or grafted to a host eye. Furthermore, sensory and, although less effective, sympathetic denervation of irides in situ led within 10 days to the ap...

journal_title：Nature

authors： Ebendal T,Olson L,Seiger A,Hedlund KO

更新日期：1980-07-03 00:00:00

abstract：:Serious concerns have been raised about the ecological effects of industrialized fishing, spurring a United Nations resolution on restoring fisheries and marine ecosystems to healthy levels. However, a prerequisite for restoration is a general understanding of the composition and abundance of unexploited fish communit...

journal_title：Nature

authors： Myers RA,Worm B

更新日期：2003-05-15 00:00:00

abstract：:The Haldane model on a honeycomb lattice is a paradigmatic example of a Hamiltonian featuring topologically distinct phases of matter. It describes a mechanism through which a quantum Hall effect can appear as an intrinsic property of a band structure, rather than being caused by an external magnetic field. Although p...

journal_title：Nature

authors： Jotzu G,Messer M,Desbuquois R,Lebrat M,Uehlinger T,Greif D,Esslinger T

更新日期：2014-11-13 00:00:00

abstract：:Temperature is a primary driver of the distribution of biodiversity as well as of ecosystem boundaries. Declining temperature with increasing elevation in montane systems has long been recognized as a major factor shaping plant community biodiversity, metabolic processes, and ecosystem dynamics. Elevational gradients,...

journal_title：Nature

authors： Mayor JR,Sanders NJ,Classen AT,Bardgett RD,Clément JC,Fajardo A,Lavorel S,Sundqvist MK,Bahn M,Chisholm C,Cieraad E,Gedalof Z,Grigulis K,Kudo G,Oberski DL,Wardle DA

更新日期：2017-02-02 00:00:00

abstract：:Steroid hormone receptors are a class of cell-specific trans-acting transcription regulatory factors whose activity is controlled by specific binding of the hormone. The hormone-receptor complex appears to associate with promoter/enhancer elements of specific target genes, resulting in activation of transcription (see...

journal_title：Nature

authors： Green S,Chambon P

更新日期：1987-01-01 00:00:00

abstract：:Transformation of the well-studied maize transposable elements into other plant species should enable transposon tagging methodology to be used for the isolation of interesting genes in the heterologous host. Here we describe the isolation of a transposon-tagged male sterile mutant in Arabidopsis thaliana using the ma...

journal_title：Nature

authors： Aarts MG,Dirkse WG,Stiekema WJ,Pereira A

更新日期：1993-06-24 00:00:00

abstract：:Electric-field-induced charge separation (polarization) is the most fundamental manifestation of the interaction of light with matter and a phenomenon of great technological relevance. Nonlinear optical polarization produces coherent radiation in spectral ranges inaccessible by lasers and constitutes the key to ultima...

journal_title：Nature

authors： Sommer A,Bothschafter EM,Sato SA,Jakubeit C,Latka T,Razskazovskaya O,Fattahi H,Jobst M,Schweinberger W,Shirvanyan V,Yakovlev VS,Kienberger R,Yabana K,Karpowicz N,Schultze M,Krausz F

更新日期：2016-06-02 00:00:00

abstract：:Lecithin is a major structural component of biological membranes. Because of their amphipathic nature, lecithin and related phospholipids tend to aggregate as bilayer structures in which the hydrophilic head groups are orientated towards the surface and the hydrophobic hydrocarbon chains towards the interior. A detail...

journal_title：Nature

authors： Pearson RH,Pascher I

更新日期：1979-10-11 00:00:00

abstract：:Interleukin-2 (IL-2) has a key role in the antigen-specific clonal growth of T lymphocytes, by virtue of its interaction with a specific cell-surface receptor (IL-2R). The growth signal seems to be delivered by IL-2 bound to the high-affinity, but not the low-affinity, receptor. Genes encoding IL-2 and its receptor (t...

journal_title：Nature

authors： Hatakeyama M,Minamoto S,Uchiyama T,Hardy RR,Yamada G,Taniguchi T

更新日期：1985-12-05 00:00:00

abstract：:Interactions of CD4 with the class II major histocompatibility complex (MHC) are crucial during thymic ontogeny and subsequently for helper and cytotoxic functions of CD4+CD8- T lymphocytes. CD4 is the receptor for the T-lymphotropic human immunodeficiency virus and binds its envelope glycoprotein, gp120. The residues...

journal_title：Nature

authors： Clayton LK,Sieh M,Pious DA,Reinherz EL

更新日期：1989-06-15 00:00:00

abstract：: ...

journal_title：Nature

authors： Masood E

更新日期：2018-11-01 00:00:00

abstract：:The nature and length scales of charge screening in complex oxides are fundamental to a wide range of systems, spanning ceramic voltage-dependent resistors (varistors), oxide tunnel junctions and charge ordering in mixed-valence compounds. There are wide variations in the degree of charge disproportionation, length sc...

journal_title：Nature

authors： Ohtomo A,Muller DA,Grazul JL,Hwang HY

更新日期：2002-09-26 00:00:00

abstract：:Mammal-like reptiles of the order Therapsida document the emergence of mammals from more primitive synapsids and are of unique zoological and palaeontological interest on that account. Therapsids, first appearing in the Early Permian, were thought to become extinct in the Middle Jurassic, soon after the Late Triassic ...

journal_title：Nature

authors： Fox RC,Youzwyshyn GP,Krause DW

更新日期：1992-07-16 00:00:00

abstract：:Peptidoglycan (PG), an essential structure in the cell walls of the vast majority of bacteria, is critical for division and maintaining cell shape and hydrostatic pressure. Bacteria comprising the Chlamydiales were thought to be one of the few exceptions. Chlamydia harbour genes for PG biosynthesis and exhibit suscept...

journal_title：Nature

authors： Liechti GW,Kuru E,Hall E,Kalinda A,Brun YV,VanNieuwenhze M,Maurelli AT

更新日期：2014-02-27 00:00:00

abstract：:Oxygen, one of the most abundant elements on Earth, often forms an undesired interstitial impurity or ceramic phase (such as an oxide particle) in metallic materials. Even when it adds strength, oxygen doping renders metals brittle1-3. Here we show that oxygen can take the form of ordered oxygen complexes, a state in ...

journal_title：Nature

authors： Lei Z,Liu X,Wu Y,Wang H,Jiang S,Wang S,Hui X,Wu Y,Gault B,Kontis P,Raabe D,Gu L,Zhang Q,Chen H,Wang H,Liu J,An K,Zeng Q,Nieh TG,Lu Z

更新日期：2018-11-01 00:00:00

abstract：:Many proteins are expressed in distinct embryonic and adult forms. However, in most cases we do not know why the embryonic form of proteins is required. This question can be readily addressed for the acetylcholine receptor (AChR) because developmentally specified modifications of this ligand-gated ion channel can be d...

journal_title：Nature

authors： Jaramillo F,Vicini S,Schuetze SM

更新日期：1988-09-01 00:00:00

abstract：:Very large collisions in the asteroid belt could lead temporarily to a substantial increase in the rate of impacts of meteorites on Earth. Orbital simulations predict that fragments from such events may arrive considerably faster than the typical transit times of meteorites falling today, because in some large impacts...

journal_title：Nature

authors： Heck PR,Schmitz B,Baur H,Halliday AN,Wieler R

更新日期：2004-07-15 00:00:00