Abstract:
:Lecithin is a major structural component of biological membranes. Because of their amphipathic nature, lecithin and related phospholipids tend to aggregate as bilayer structures in which the hydrophilic head groups are orientated towards the surface and the hydrophobic hydrocarbon chains towards the interior. A detailed knowledge of the three-dimensional structure of lecithins will aid in the understanding of their role in membrane structure and function, but is still lacking. To this end we have now crystallised and solved the molecular structure of 1,2-dimyristoyl-sn-glycero-3-phosphorylcholine (DMPC), a lecithin species in the naturally occurring configuration. This compound crystallises from a water-containing solution, with two water molecules (5% w/w) of hydration.
journal_name
Naturejournal_title
Natureauthors
Pearson RH,Pascher Idoi
10.1038/281499a0subject
Has Abstractpub_date
1979-10-11 00:00:00pages
499-501issue
5731eissn
0028-0836issn
1476-4687journal_volume
281pub_type
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