A rapid presentation event-related functional magnetic resonance imaging study of response inhibition in macaque monkeys.

abstract：:To assess the significance of the association between apolipoprotein E (APOE) epsilon 4 allele and amyloid beta-peptide (A-beta) deposits in the brain, we performed APOE-genotyping and measured the density of A-beta deposits, neuritic plaques and neurofibrillary tangles in 27 cases from the Charles Foix clinico-pathol...

journal_title：Neuroscience letters

authors： Berr C,Hauw JJ,Delaère P,Duyckaerts C,Amouyel P

更新日期：1994-09-12 00:00:00

abstract：:Rehabilitation is a process which favors recovery after brain damage involving motor systems, and neural plasticity is the only real resource the brain has for inducing neurobiological events in order to bring about re-adaptation. Rats were placed on a treadmill and made to walk, in different groups, at different velo...

journal_title：Neuroscience letters

authors： Vázquez-Hernández N,González-Tapia DC,Martínez-Torres NI,González-Tapia D,González-Burgos I

更新日期：2017-09-14 00:00:00

abstract：:Quantitative receptor autoradiography was used to study dopamine (DA) receptors in dorsal striatum and its projection regions in brains from individuals dying with Huntington's disease (HD) and controls. Heterogeneous loss of both D1 and D2 receptors was present in the striatum of early and late stage HD brains. The d...

journal_title：Neuroscience letters

authors： Richfield EK,O'Brien CF,Eskin T,Shoulson I

更新日期：1991-10-28 00:00:00

abstract：:Pineal concentrations of 5-methoxytryptamine, 5-methoxytryptophol, 5-methoxyindole acetic acid and melatonin were determined using high performance liquid chromatography following administration of different monoamine oxidase (MAO) inhibitors (clorgyline, pargyline and deprenyl) to golden hamsters. Plasma concentratio...

journal_title：Neuroscience letters

authors： Raynaud F,Pévet P

更新日期：1991-02-25 00:00:00

abstract：:Attention deficit hyperactivity disorder (ADHD) is a developmental disorder characterized by inattentiveness, motor hyperactivity and impulsivity. According to neuroimaging data, the neural substrate underlying ADHD seems to involve fronto-striatal circuits and the cerebellum. However, there are important discrepancie...

journal_title：Neuroscience letters

authors： Carmona S,Vilarroya O,Bielsa A,Trèmols V,Soliva JC,Rovira M,Tomàs J,Raheb C,Gispert JD,Batlle S,Bulbena A

更新日期：2005-12-02 00:00:00

abstract：:It is known that over-exercise or forced running interrupts the regular ovulatory (estrous) cycle in female mammals, including women. The serotonin content of the brain changes under stress conditions. In this experiment, radiofrequency lesions were made in the dorsal (DRL) or median (MRL) raphe nuclei of the midbrain...

journal_title：Neuroscience letters

authors： Shimizu H,Yamanouchi K

更新日期：2011-05-20 00:00:00

abstract：:Genetic factors have been reported to contribute to the liability of suicide. We aimed to investigate functional polymorphisms in eight genes (serotonin transporter, SLC6A4; receptors, 5HTR1A, 1B, 5HTR2A; Tryptophan Hydroxylase, TPH1, TPH2; Monoamine Oxidase, MAOA and G Protein Subunit Beta 3, GNB3) to investigate the...

journal_title：Neuroscience letters

authors： Pompili M,Gentile G,Scassellati C,Bonvicini C,Innamorati M,Erbuto D,Montebovi F,Ducci G,Forte A,De Pisa E,Ferracuti S,Serafini G,De Luca V,Amore M,Simmaco M,Girardi P

更新日期：2017-08-24 00:00:00

abstract：:We compared the modulation of GABA (gamma-aminobutyric acid)-activated currents by benzodiazepines in recombinant GABAA receptors containing either one of two alpha subunits, alpha 1 or alpha 6. Lüddens et al. (Nature, 346 (1990) 648-651) have previously demonstrated that the alpha 6 subunit is part of a cerebellar re...

journal_title：Neuroscience letters

authors： Kleingoor C,Ewert M,von Blankenfeld G,Seeburg PH,Kettenmann H

更新日期：1991-09-16 00:00:00

abstract：:Vlgr1 (very large G-protein coupled receptor 1) knockout mice against hybrid backgrounds of the 129/Ola and C57BL/6 mouse strains show hearing deficit and high susceptibility to audiogenic seizures. The present study examined how hearing impairment and susceptibility to audiogenic seizures in Vlgr1-deficient mice chan...

journal_title：Neuroscience letters

authors： Yagi H,Noguchi Y,Kitamura K,Sato M

更新日期：2009-09-18 00:00:00

abstract：:Interhemispheric coherence for 19 channel EEG activity collected over a three year period from 184 men and women who relaxed in a quiet, darkened chamber showed significant increased coherence between caudal temporal regions for the 11 Hz frequency band during increased (>∼8 nT) global geomagnetic activity at the time...

journal_title：Neuroscience letters

authors： Saroka KS,Caswell JM,Lapointe A,Persinger MA

更新日期：2014-02-07 00:00:00

abstract：:GABAergic modulation of enkephalin, substance P and glutamic acid decarboxylase (GAD67) gene expression and the alterations induced by dopamine receptor blockade were studied in the rat striatum. Following subchronic treatment with the GABA-A agonist muscimol, the GABA-B agonist baclofen or the GABA transaminase inhib...

journal_title：Neuroscience letters

authors： Jolkkonen J,Jenner P,Marsden CD

更新日期：1994-10-24 00:00:00

abstract：:Alzheimer's disease (AD) is characterized by amyloid plaques, neuritic degenerations, disturbed glutamatergic neurotransmission and a peculiar inflammatory response. Diffuse plaques develop into neuritic plaques when neurites undergo degeneration in the plaque area. Hyperphosphorylation of tau proteins is a major step...

journal_title：Neuroscience letters

authors： Hüll M,Eistetter J,Fiebich BL,Bauer J

更新日期：1999-02-12 00:00:00

abstract：:The ergoline derivatives, nicergoline (NIC) or dihydroergocristine (DHE) were administered at various doses (0.1, 0.5 and 1 mg/kg) to aged male rats subjected to labyrinth unilateral lesion (LBX). The nystagmus rate appeared to be lower in animals treated with DHE or NIC 1mg/kg than in saline-injected rats, when obser...

journal_title：Neuroscience letters

authors： Rampello L,Drago F

更新日期：1999-05-28 00:00:00

abstract：:Aquaporin-1 (AQP1) is a water channel expressed in the choroid plexus and participates in forming cerebrospinal fluid. Interestingly, reactive astrocytes also express AQP1 in the central nervous system under some pathological conditions. On the other hand, 3-nitropropionic acid (3NP) is a mitochondrial toxin that caus...

journal_title：Neuroscience letters

authors： Hoshi A,Tsunoda A,Yamamoto T,Tada M,Kakita A,Ugawa Y

更新日期：2016-07-28 00:00:00

abstract：:Down syndrome is the most common genetic cause of intellectual disability and occurs due to the trisomy of human chromosome 21. Adolescent and adult brains from humans with Down syndrome exhibit various neurological phenotypes including a reduction in the size of the corpus callosum, hippocampal commissure and anterio...

journal_title：Neuroscience letters

authors： Jain S,Watts CA,Chung WCJ,Welshhans K

更新日期：2020-01-01 00:00:00

abstract：:Sex differences in basal extracellular striatal dopamine concentrations in gonadectomized male and female rats have been reported previously. In the current experiment, estrous cycle-dependent variation, sex differences and the effect of gonadectomy on extracellular striatal dopamine concentrations were determined usi...

journal_title：Neuroscience letters

authors： Xiao L,Becker JB

更新日期：1994-10-24 00:00:00

abstract：:It has long been known that primary neurons in the brain and spinal cord exhibit very distinctive dendritic structures. However, it remains unclear whether dendritic processing for signal propagation and channel activation over dendrites is a function of the cell type-specific dendritic structure. By applying an exten...

journal_title：Neuroscience letters

authors： Kim H,Heckman CJ

更新日期：2015-11-16 00:00:00

abstract：:Our previous genetic and proteomic studies demonstrated that dynamin 1 is significantly associated with nicotine dependence (ND) in human smokers and its expression is highly modulated by nicotine in the brains of animals. To provide further molecular evidence for the involvement of dynamin 1 in the etiology of ND, we...

journal_title：Neuroscience letters

authors： Xu Q,Li MD

更新日期：2011-02-11 00:00:00

abstract：:[3H]Glibenclamide, a potent ATP-sensitive K+ channel blocker, is a specific ligand for the identification of the sulfonylureas receptors which are closely related to ATP-sensitive K+ channels. In order to determine the pre- or postsynaptic localization of these receptors in the rat hippocampus, we studied the effects ...

journal_title：Neuroscience letters

authors： Tremblay E,Zini S,Ben-Ari Y

更新日期：1991-06-10 00:00:00

abstract：:Loss of ovarian function, such as occurs with menopause in human beings and ovariectomy in rodents, results in weight gain. Using multiple-time regression analysis, a sensitive technique for quantifying blood-to-brain transport of peptides and polypeptides, we found that mice ovariectomized for at least 5 weeks had ma...

journal_title：Neuroscience letters

authors： Kastin AJ,Akerstrom V,Maness LM

更新日期：2001-09-07 00:00:00

abstract：:In fetal and adult human brains, calbindin immunoreactivity (CB-ir) of neostriatal neuropil showed inhomogeneous pattern. A mosaic of CB-ir neuropil patches matching the acetylcholinesterase (AChE)-reactive patches and most of the encapsulated cell-dense islands was distributed in a lighter stained background matrix. ...

journal_title：Neuroscience letters

authors： Letinić K,Kostović I

更新日期：1996-12-20 00:00:00

abstract：:In the present experiment we compared differences in extracellular norepinephrine levels in vivo within the olfactory bulb of intact and castrated male rats following infusion of the norepinephrine transport inhibitors, nisoxetine and tomoxetine. With this approach it was possible to assess whether dynamic changes in ...

journal_title：Neuroscience letters

authors： Shang Y,Dluzen DE

更新日期：2002-08-09 00:00:00

abstract：:We examined the effects of ibotenic acid induced unilateral lesion of the nucleus basalis magnocellularis (nBM) on carbachol- and serotonin-stimulated phosphoinositide (PI) breakdown in miniprisms obtained from rat fronto-parietal cortex 1 week following the lesion. Lesion-side muscarinic and serotoninergic receptor r...

journal_title：Neuroscience letters

authors： Erfurth A,Holmes TC

更新日期：1995-06-23 00:00:00

abstract：:In freshly dissociated viable cells of early postnatal mouse cerebellum, O1 antigen-positive oligodendrocytes have been eliminated by complement dependent immunocytolysis. Before seeding residual cells in culture, O4 antigen-positive cells were immunolabeled by O4 antibody which had been directly conjugated with rhoda...

journal_title：Neuroscience letters

authors： Sommer I,Schachner M

更新日期：1982-04-16 00:00:00

abstract：:Chronic exposure of cultured canine cerebral vascular smooth muscle cells to ethanol (10-400 mM) for 1-5 days resulted in significant concentration-dependent elevation in resting intracellular free calcium ([Ca2+]i) levels. Preincubation of these cultured vascular cells with inhibitors of protein kinase C (PKC), staur...

journal_title：Neuroscience letters

authors： Zheng T,Li W,Zhang A,Altura BT,Altura BM

更新日期：1998-01-30 00:00:00

abstract：:Postoperative cognitive dysfunction (POCD) is a common disorder of cognitive functions in aged patients following anesthesia and surgery. α7-nicotinic acetylcholine receptors (α7-nAChR) plays a regulatory role in cognitive processes and is involved in cognitive deficits. This study aims to observe the effect of electr...

journal_title：Neuroscience letters

authors： Liu PR,Zhou Y,Zhang Y,Diao S

更新日期：2017-10-17 00:00:00

abstract：:Effects of intrathecally (i.t.) administered R-phenylisopropyl adenosine (R-PIA), an adenosine A1 receptor agonist, on presumed pain behaviour were assessed in a rat model of chronic central pain. Spinal cord injury was induced photochemically via laser irradiation of the spinal cord after intravenous injection of ery...

journal_title：Neuroscience letters

authors： Sjölund KF,von Heijne M,Hao JX,Xu XJ,Sollevi A,Wiesenfeld-Hallin Z

更新日期：1998-02-27 00:00:00

abstract：:Wild-type neuronal calcium-binding protein VILIP (visinin-like protein), and a myristoylation mutant of VILIP which lacks the consensus sequence for N-terminal myristoylation, have been stably transfected in PC12 cells. Immunocytochemical studies of VILIP-transfected PC12 cells have revealed the wild-type VILIP is str...

journal_title：Neuroscience letters

authors： Spilker C,Gundelfinger ED,Braunewell KH

更新日期：1997-04-04 00:00:00

abstract：:We investigated microvascular damage in areas with magnetic resonance imaging (MRI)-defined apparent diffusion coefficient reduction (ADC-R) in a rat model of thromboembolic occlusion of the middle cerebral artery. Rats received either intracarotid recombinant tissue plasminogen activator (rt-PA) or saline. Microvascu...

journal_title：Neuroscience letters

authors： Vosko MR,Busch E,Burggraf D,Bültemeier G,Hamann GF

更新日期：2003-12-26 00:00:00

abstract：:Postural control strategies are frequently assessed through posturography on a firm surface. Their motor efficiency is related to the coordination between center-of-gravity (CG) and center-of-pressure (CP) movements, which results from long-term training. However, when standing on a seesaw favoring pitching body motio...

journal_title：Neuroscience letters

authors： Rougier PR,Mathias M,Tanzi A

更新日期：2011-01-20 00:00:00