Different patterns of motor activity induce differential plastic changes in pyramidal neurons in the motor cortex of rats: A Golgi study.

Abstract:

:Rehabilitation is a process which favors recovery after brain damage involving motor systems, and neural plasticity is the only real resource the brain has for inducing neurobiological events in order to bring about re-adaptation. Rats were placed on a treadmill and made to walk, in different groups, at different velocities and with varying degrees of inclination. Plastic changes in the spines of the apical and basal dendrites of fifth-layer pyramidal neurons in the motor cortices of the rats were detected after study with the Golgi method. Numbers of dendritic spines increased in the three experimental groups, and thin, mushroom, stubby, wide, and branched spines increased or decreased in proportion depending on the motor demands made of each group. Along with the numerical increase of spines, the present findings provide evidence that dendritic spines' geometrical plasticity is involved in the differential performance of motor activity.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Vázquez-Hernández N,González-Tapia DC,Martínez-Torres NI,González-Tapia D,González-Burgos I

doi

10.1016/j.neulet.2017.07.040

subject

Has Abstract

pub_date

2017-09-14 00:00:00

pages

27-31

eissn

0304-3940

issn

1872-7972

pii

S0304-3940(17)30612-2

journal_volume

657

pub_type

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