Abstract：
:Three Plasmodium falciparum serine repeat antigen (SERA) protein peptides were studied by NMR and structure calculations being done in 70:30 water:trifluoroethanol solution. Peptide 22834 was shown to be immunogenic and protective against malaria in Aotus monkeys, whilst native peptide 6737 and its analogue 14096 did not present protection against the disease in these monkeys. Results showed a relationship between these peptides' secondary structure and their function as immunogen against malaria.
journal_name
Biochimiejournal_title
Biochimieauthors
Cubillos M,Alba MP,Bermúdez A,Trujillo M,Patarroyo MEdoi
10.1016/s0300-9084(03)00136-6keywords:
subject
Has Abstractpub_date
2003-07-01 00:00:00pages
651-7issue
7eissn
0300-9084issn
1638-6183pii
S0300908403001366journal_volume
85pub_type
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