Effect of liver plasma membrane fluidity on endogenous phospholipase A2 activity.

Abstract:

:Investigations have been carried out on the influence of the phospholipid composition and the physicochemical properties of rat liver plasma membranes on the endogenous activity of membrane-bound phospholipase A2. The membrane phospholipid composition was modified by the incorporation of different phospholipids in the lipid bilayer by the aid of lipid transfer proteins. The results indicate that the endogenous activity of phospholipase A2 in liver plasma membranes depends upon membrane fluidity and not upon the presence of a specific phospholipid in the enzyme's microenvironment.

journal_name

Biochimie

journal_title

Biochimie

authors

Petkova DH,Momchilova-Pankova AB,Koumanov KS

doi

10.1016/0300-9084(87)90153-2

subject

Has Abstract

pub_date

1987-11-01 00:00:00

pages

1251-5

issue

11-12

eissn

0300-9084

issn

1638-6183

pii

0300-9084(87)90153-2

journal_volume

69

pub_type

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