Abstract:
:The co-existence of viruses and organisms for millions of years has influenced the evolution of both. Various viral strategies to enter a host and take over the control of cells to produce virus progeny have developed. Several antiviral (immune) responses have also been developed. The apoptotic death program is a conserved feature of eukaryotic cells. In multicellular organisms the binding and engulfment of apoptotic material is considered to be the end stage of the apoptotic process. Because of its importance, it seems probable that viruses have targeted this ancient removal system to suppress immune responses and to establish or maintain infection. The possibility that the hepatitis B virus has evolved such a mechanism, termed "viral apoptotic-like mimicry", is presented here.
journal_name
Trends Immunoljournal_title
Trends in immunologyauthors
Vanlandschoot P,Leroux-Roels Gdoi
10.1016/s1471-4906(03)00026-7keywords:
subject
Has Abstractpub_date
2003-03-01 00:00:00pages
144-7issue
3eissn
1471-4906issn
1471-4981pii
S1471490603000267journal_volume
24pub_type
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pub_type: 传,历史文章,杂志文章,评审
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